Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation

Hepatic Steatosis ◽

Receptor Agonist ◽

Nuclear Translocation ◽

Related Factor ◽

Nuclear Factor ◽

Glucagon Like Peptide ◽

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

Diabetes ◽

10.2337/db09-0685 ◽

2009 ◽

Vol 58 (12) ◽

pp. 2851-2862 ◽

Cited By ~ 144

Author(s):

Daniel A. Cunha ◽

Laurence Ladrière ◽

Fernanda Ortis ◽

Mariana Igoillo-Esteve ◽

Esteban N. Gurzov ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Β Cells ◽

Pancreatic Β Cells ◽

Glucagon Like Peptide ◽

Molecular and ultrastructure study of endoplasmic reticulum stress in hepatic steatosis: role of hepatocyte nuclear factor 4α and inflammatory mediators

Histochemistry and Cell Biology ◽

10.1007/s00418-019-01823-2 ◽

2019 ◽

Vol 153 (1) ◽

pp. 49-62 ◽

Cited By ~ 3

Author(s):

Salwa M. Abo El-khair ◽

Fatma M. Ghoneim ◽

Dalia A. Shabaan ◽

Ayman Z. Elsamanoudy

Keyword(s):

Endoplasmic Reticulum ◽

Hepatic Steatosis ◽

Inflammatory Mediators ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Ultrastructure Study ◽

Hepatocyte Nuclear Factor 4Α

Faculty Opinions recommendation of Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732648152.793573478 ◽

2020 ◽

Author(s):

Michael Briggs

Keyword(s):

Endoplasmic Reticulum ◽

Inflammatory Response ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Induced Apoptosis

Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2020.115036 ◽

2020 ◽

Vol 399 ◽

pp. 115036 ◽

Cited By ~ 3

Author(s):

Kyung Hwan Jegal ◽

Eun Ok Kim ◽

Jae Kwang Kim ◽

Sang Mi Park ◽

Dae Hwa Jung ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Related Factor ◽

Nuclear Factor

Glucagon-like peptide-1 preserves non-alcoholic fatty liver disease through inhibition of the endoplasmic reticulum stress-associated pathway

Hepatology Research ◽

10.1111/hepr.12551 ◽

2015 ◽

Vol 46 (4) ◽

pp. 343-353 ◽

Cited By ~ 25

Author(s):

Na Ao ◽

Jing Yang ◽

Xiaochen Wang ◽

Jian Du

Keyword(s):

Endoplasmic Reticulum ◽

Liver Disease ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Alcoholic Fatty Liver ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Alcoholic Fatty Liver Disease

Glucagon-like peptide-1 attenuates endoplasmic reticulum stress–induced apoptosis in H9c2 cardiomyocytes during hypoxia/reoxygenation through the GLP-1R/PI3K/Akt pathways

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/s00210-019-01625-2 ◽

2019 ◽

Vol 392 (6) ◽

pp. 715-722 ◽

Cited By ~ 1

Author(s):

Gaopeng Guan ◽

Jun Zhang ◽

Shengyuan Liu ◽

Wenyin Huang ◽

Ying Gong ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

H9c2 Cardiomyocytes ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1 ◽

Induced Apoptosis ◽

Hypoxia Reoxygenation

Glucagon-like Peptide-1 Receptor Agonist Liraglutide Inhibits Endothelin-1 in Endothelial Cell by Repressing Nuclear Factor-Kappa B Activation

Cardiovascular Drugs and Therapy ◽

10.1007/s10557-013-6463-z ◽

2013 ◽

Vol 27 (5) ◽

pp. 371-380 ◽

Cited By ~ 51

Author(s):

Yao Dai ◽

Jawahar L. Mehta ◽

Mingwei Chen

Keyword(s):

Endothelial Cell ◽

Receptor Agonist ◽

Nuclear Factor Kappa B ◽

Nuclear Factor ◽

Endothelin 1 ◽

Nuclear Factor Kappa ◽

Glucagon Like Peptide ◽

Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice

Molecular Metabolism ◽

10.1016/j.molmet.2017.09.001 ◽

2017 ◽

Vol 6 (11) ◽

pp. 1360-1370 ◽

Cited By ~ 21

Author(s):

Hani Jouihan ◽

Sarah Will ◽

Silvia Guionaud ◽

Michelle L. Boland ◽

Stephanie Oldham ◽

...

Keyword(s):

Hepatic Steatosis ◽

Receptor Agonist ◽

Obeticholic Acid ◽

Glucagon Like Peptide ◽

Glucagon-like peptide-1 production in the GLUTag cell line is impaired by free fatty acids via endoplasmic reticulum stress

Metabolism ◽

10.1016/j.metabol.2014.02.012 ◽

2014 ◽

Vol 63 (6) ◽

pp. 800-811 ◽

Cited By ~ 29

Author(s):

Hiroto Hayashi ◽

Ren Yamada ◽

Siddhartha Shankar Das ◽

Taiki Sato ◽

Aki Takahashi ◽

...

Keyword(s):

Fatty Acids ◽

Endoplasmic Reticulum ◽

Free Fatty Acids ◽

Cell Line ◽

Glucagon Like Peptide ◽

Cyclic AMP-mediated pleiotropic effects of glucagon-like peptide-1 receptor activation. Focus on “Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a”

AJP Cell Physiology ◽

10.1152/ajpcell.00419.2012 ◽

2013 ◽

Vol 304 (6) ◽

pp. C505-C507 ◽

Cited By ~ 6

Author(s):

Yumei Ye ◽

Yochai Birnbaum

Keyword(s):

Endoplasmic Reticulum ◽

Cyclic Amp ◽

High Glucose ◽

Receptor Activation ◽

Pleiotropic Effects ◽

Cardiomyocyte Apoptosis ◽

Glucagon Like Peptide ◽