Pectin-based films and coatings with plant extracts as natural preservatives: A systematic review

The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients’ adherence to reducing food and caloric intake. The aim of this systematic review was to assess efficacy and safety of the most commonly used bioactive phytochemicals with appetite/hunger-suppressing and/or satiety/fullness-increasing properties. To be eligible, studies needed to have included at least 10 patients per group aged 18 years or older with no serious health problems except for overweight or obesity. Of those studies, 32 met the inclusion criteria, in which 27 different plants were tested alone or as a combination, regarding their efficacy in suppressing appetite/hunger and/or increasing satiety/fullness. The plant extracts most tested were derived from Camellia sinensis (green tea), Capsicum annuum, and Coffea species. None of the plant extracts tested in several trials showed a consistent positive treatment effect. Furthermore, only a few adverse events were reported, but none serious. The findings revealed mostly inconclusive evidence that the tested bioactive phytochemicals are effective in suppressing appetite/hunger and/or increasing satiety/fullness. More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.

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Applicability of Plant Extracts in Preclinical Studies of Melanoma: A Systematic Review

Mediators of Inflammation ◽

10.1155/2018/6797924 ◽

2018 ◽

Vol 2018 ◽

pp. 1-28 ◽

Cited By ~ 9

Author(s):

Kamylla Rafaella Sena Albuquerque ◽

Nívea Maria Pacheco ◽

Thalia del Rosario Loyo Casao ◽

Fabiana Cristina Silveira Alves de Melo ◽

Rômulo Dias Novaes ◽

...

Keyword(s):

Systematic Review ◽

Plant Extracts ◽

Statistical Tests ◽

Preclinical Studies ◽

Murine Models ◽

Bias Analysis ◽

Aggressive Form ◽

Cell Cycle Modulation ◽

Search Filters ◽

Melanoma Treatment

Melanoma is the most aggressive form of skin cancer and arises from melanocyte gene mutation. This disease is multifactorial, but its main cause is the excessive exposure to ultraviolet radiation. Currently, available chemotherapy has shown little expressive results, which may justify the high use of natural products to treat this cancer. We performed a systematic review to compile the results of studies carried out in murine models and investigated the effect of plant extracts on melanoma treatment. Papers were selected in MEDLINE/Pubmed and Scopus according to the PRISM statement. Search filters were developed using three parameters: plant extract, melanoma, and animal model. The 35 identified studies were all submitted to the criteria described in the ARRIVE guidelines. The different extracts showed antiangiogenic, antimetastatic, antioxidant, and anti-inflammatory activity, and also proved to be effective in cell cycle modulation and apoptosis evasion. Bias analysis evidenced the absence of standardized experimental designs, as well as failures in statistical tests and in the presentation of results. The analysis of the studies suggests that the use of plant extracts is effective for the treatment of melanoma in murine models.

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Botanical biopesticides: research and development trends, a focus on the Annonaceae family

Revista Colombiana de Ciencias Hortícolas ◽

10.17584/rcch.2019v13i3.9489 ◽

2019 ◽

Vol 13 (3) ◽

pp. 371-383

Author(s):

Ana Isabel Giraldo-Rivera ◽

Gloria-Edith Guerrero-Alvarez

Keyword(s):

Public Health ◽

Systematic Review ◽

Research And Development ◽

Plant Extracts ◽

Subsequent Development ◽

Review Of The Literature ◽

Development Trends ◽

Market Trends ◽

Pesticide Regulation ◽

Botanical Extracts

This document analyzed research and development trends related to chemical, biological and economical biopesticides based on plant extracts, with emphasis on the Annonaceae family. A systematic review of the literature between 1947 and 2018 was done with an advance search equation in a specialized data base. This paper contains the development of plant bio pesticides, their modes of action, the more prominent families according to their bioactivity and the secondary metabolites that exert control over pests that are significant in agriculture and public health. The dynamics of publications, at the national and international levels, were identified, along with the countries that lead research, patents assigned in the last 20 years, market trends and bio pesticide regulation. The reviewed research is relevant to bioprospecting plant extracts with potential insecticidal activity and to the subsequent development of biocides using botanical extracts; the Annonaceae family is promising.

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USE OF NATURAL PRESERVATIVES IN SEAFOOD: PLANT EXTRACTS, EDIBLE FILM AND COATING

Journal of Food and Health Science ◽

10.3153/jfhs15004 ◽

2015 ◽

Cited By ~ 3

Author(s):

Nuray Erkan

Keyword(s):

Plant Extracts ◽

Edible Film ◽

Natural Preservatives

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Hepato-Protective Effect from Natural Compounds, Biological Products and Medicinal Plant Extracts on Antitubercular Drug-Induced Liver Injuries: A Systematic Review

10.35248/2167-0412.19.8.339 ◽

2019 ◽

Vol 08 (05) ◽

Author(s):

Oscar Abelardo Ramírez-Marroquín ◽

María Adelina Jiménez-Arellanes

Keyword(s):

Systematic Review ◽

Medicinal Plant ◽

Protective Effect ◽

Plant Extracts ◽

Natural Compounds ◽

Antitubercular Drug ◽

Drug Induced ◽

Biological Products ◽

Liver Injuries ◽

Medicinal Plant Extracts

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Plant Extracts in the Bone Repair Process: A Systematic Review

Mediators of Inflammation ◽

10.1155/2019/1296153 ◽

2019 ◽

Vol 2019 ◽

pp. 1-22 ◽

Cited By ~ 1

Author(s):

Lyvia Lopes Miranda ◽

Vanessa de Paula Guimarães-Lopes ◽

Luciana Schulthais Altoé ◽

Mariáurea Matias Sarandy ◽

Fabiana Cristina Silveira Alves Melo ◽

...

Keyword(s):

Systematic Review ◽

Animal Models ◽

Plant Extracts ◽

Bone Repair ◽

Bone Matrix ◽

Bone Lesion ◽

Public Health Problem ◽

Fracture Repair ◽

Bone Lesions ◽

Anti Inflammatory

Bone lesions are an important public health problem, with high socioeconomic costs. Bone tissue repair is coordinated by an inflammatory dynamic process mediated by osteoprogenitor cells of the periosteum and endosteum, responsible for the formation of a new bone matrix. Studies using antioxidant products from plants for bone lesion treatment have been growing worldwide. We developed a systematic review to compile the results of works with animal models investigating the anti-inflammatory activity of plant extracts in the treatment of bone lesions and analyze the methodological quality of the studies on this subject. Studies were selected in the PubMed/MEDLINE, Scopus, and Web of Science databases according to the PRISMA statement. The research filters were constructed using three parameters: animal model, bone repair, and plant extracts. 31 full-text articles were recovered from 10 countries. Phytochemical prospecting was reported in 15 studies (48.39%). The most common secondary metabolites were flavonoids, cited in 32.26% studies (n=10). Essential criteria to in vivo animal studies were frequently underreported, suggesting publication bias. The animals treated with plant extracts presented positive results in the osteoblastic proliferation, and consequently, this treatment accelerated osteogenic differentiation and bone callus formation, as well as bone fracture repair. Possibly, these results are associated with antioxidant, regenerative, and anti-inflammatory power of the extracts. The absence or incomplete characterization of the animal models, treatment protocols, and phytochemical and toxicity analyses impairs the internal validity of the evidence, making it difficult to determine the effectiveness and safety of plant-derived products in bone repair.

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Applicability of Isolates and Fractions of Plant Extracts in Murine Models in Type II Diabetes: A Systematic Review

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2016/3537163 ◽

2016 ◽

Vol 2016 ◽

pp. 1-25 ◽

Cited By ~ 1

Author(s):

Gabriela Diniz Pinto Coelho ◽

Vanessa Soares Martins ◽

Laura Vieira do Amaral ◽

Rômulo Dias Novaes ◽

Mariáurea Matias Sarandy ◽

...

Keyword(s):

Systematic Review ◽

Plant Extracts ◽

Type Ii Diabetes ◽

Study Groups ◽

Type Ii Diabetes Mellitus ◽

Type Ii ◽

Glucose Levels ◽

Animal Data ◽

Plasma Insulin Levels ◽

Clinical Conditions

Type II diabetes mellitus is one of the most common public health problems worldwide. Its increasing prevalence in several countries and the difficult metabolic control of individuals with the disease justify studying strategies for primary prevention. The population has sought alternative and cheaper ways to treat the disease, including the use of plants considered medicinal by the population. In this study, we carried out a systematic review on the applicability of isolates and fractions of plant extracts in animal models in type II diabetes. A literature search was performed in MEDLINE/PubMed and Scopus databases. Studies using other experimental animals (horses, rabbits, and monkeys) and humans as well as articles in Chinese, German, and Russian were excluded. We assessed the quality of the studies included by using the criteria described in the ARRIVE guidelines. In general, the animals that received fractions or isolates presented reduced blood glucose levels, normalization of body weight and plasma insulin levels, and reduced total triglycerides and cholesterol. In addition, we observed wide variation among the analyzed parameters, which hindered comparison between the studies found. In further studies, standardized reports and experimental design would help to establish comparable study groups and advance the overall knowledge, thus facilitating translatability from animal data to human clinical conditions.

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Biocidal Potential of Plants Extracts Against Wood-Degrading Microbes and Their In-Vitro Application on Wood: As Promising Wood Natural Preservatives

10.21203/rs.3.rs-138701/v1 ◽

2021 ◽

Author(s):

Amina Ifthkar ◽

Faiza Jabeen ◽

Saima Mirza ◽

Afshan Abbas ◽

Tahira Younis ◽

...

Keyword(s):

Plant Extracts ◽

Ethanol Extract ◽

Wood Protection ◽

Whole Plant ◽

Increasing Demand ◽

Decaying Wood ◽

Natural Preservatives ◽

Fungal Deterioration ◽

Microbial Attack

Abstract Background: Besides the increasing demand of wooden articles, there is a burning issue of microbial attack which affects the aesthetics of wood. Thus it is a current concern to protect the wooden articles from both fungal and bacterial attack by using toxin free preservatives. Results: Powder of Calotropis procera (leaves), Curcuma zedoaria (rhizome) and Swertia chirata (whole plant) was extracted with solvents like methanol, ethanol and chloroform and then the qualitative phytochemical screening was carried out, which exhibited the presence of different secondary metabolites. These extracts were also evaluated against wood degrading microbes (Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Aspergillus flavus and Aspergillus niger) isolated from decaying wood. Our study demonstrated that the ethanol extract of S. chairata showed highest bactericidal potential against E.coli (19.0mm) and A. flavus (19.33mm). This study also revealed that S. chirata exhibited strongest biocidal spectrum of action followed by C. procera and C. zedaira. It was observed that laminated veneer treated with ethanol extract of S. chirata showed strong bactericidal potential against E.coli (82.67mm). On the other hand Syzygium cumini wood treated with ethanol extract of C. zedoaria exhibited high antibacterial potential against P. aeruginosa (58.0mm). The active plant extracts showed MIC's ranged from 3.6 to 6.0 mg/ml and MBC/MFC of 4.8 and 8.4 mg/ml. Conclusion: The results demonstrated the potential effects of selected plant extracts as a natural preservative that can protect wood from bacterial and fungal deterioration. The extracts can be applied to prevent furniture deterioration and raw wood protection.

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