scholarly journals Key issues affecting the current status of infectious diseases in Chinese cattle farms and their control through vaccination

Vaccine ◽  
2021 ◽  
Author(s):  
Yingyu Chen ◽  
Yu Wang ◽  
Ian D. Robertson ◽  
Changmin Hu ◽  
Huanchun Chen ◽  
...  
Author(s):  
Sachiko Ogawa ◽  
Yoshinori Takahashi ◽  
Misako Miyazaki

Background: Although interprofessional education (IPE) has come to be considered essential in health and social care education programs, most IPE programs in Japan focus on clinical settings. However, following the 2011 Great East Japan Earthquake, IPE programs are considered essential for community development, especially in disaster-affected areas. To identify key issues for the development of IPE, we aimed to clarify the current status of IPE programs and problems in their implementation using an original questionnaire. Methods and Findings: The targets were 865 undergraduate courses that qualify students to take national registered health/social care examinations. Effective responses were received from 284 targets. Of these 284 respondents, 103 respondents had already implemented an IPE program and 181 respondents had not. Among the 103 respondents who had already implemented an IPE program, we found a tendency to collaborate with partners in clinical settings or in social settings. Furthermore, respondents who had implemented or were planning to implement an IPE program had difficulty with ‘interdisciplinary and/or extramural collaboration’ and ‘educational factors’. Conclusions: These difficulties could be considered barriers to developing effective IPE programs for community-based collaboration between health and social care professionals. Future research should investigate more specific solutions to these problems.


Oncotarget ◽  
2018 ◽  
Vol 9 (29) ◽  
pp. 20891-20907 ◽  
Author(s):  
Stanislaw Schmidt ◽  
Lars Tramsen ◽  
Bushra Rais ◽  
Evelyn Ullrich ◽  
Thomas Lehrnbecher

2011 ◽  
Vol 14 (3) ◽  
pp. 400 ◽  
Author(s):  
Ravindra B Malabadi ◽  
Advaita Ganguly ◽  
Jaime A Teixeira da Silva ◽  
Archana Parashar ◽  
Mavanur R Suresh ◽  
...  

ABSTRACT - This review highlights the advantages and current status of plant-derived vaccine development with special reference to the dengue virus. There are numerous problems involved in dengue vaccine development, and there is no vaccine against all four dengue serotypes. Dengue vaccine development using traditional approaches has not been satisfactory in terms of inducing neutralizing antibodies. Recently, these issues were addressed by showing a very good response to inducing neutralizing antibodies by plant-derived dengue vaccine antigens. This indicates the feasibility of using plant-derived vaccine antigens as a low-cost method to combat dengue and other infectious diseases. The application of new methods and strategies such as dendritic cell targeting in cancer therapy, severe acute respiratory syndrome, tuberculosis, human immune deficiency virus, and malaria might play an important role. These new methods are more efficient than traditional protocols. It is expected that in the near future, plant-derived vaccine antigens or antibodies will play an important role in the control of human infectious diseases. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.


2017 ◽  
Vol 43 (1) ◽  
pp. 42-54
Author(s):  
Insoo Kim ◽  
Kyung-Suk Lee ◽  
Hyo-Cher Kim ◽  
Hye-Seon Chae ◽  
Kyungsu Kim ◽  
...  

2021 ◽  
Vol 2 (6) ◽  
pp. 26-45
Author(s):  
Malith Kumarasinghe ◽  
W. Indralal De Silva ◽  
W. S. M. Goonatilaka

Initiation and continuation of healthy relationships among youth critical for the long-term wellbeing of the youth. Present socio-cultural environment presents numerous pitfalls which inhibit such relationships. Aim of this qualitative investigation was to describe the current status, trends and patterns of love affairs, dating and sexual behaviour among unmarried youth in Sri Lanka. Case studies, key informant interviews and focus group discussions were selected as methods of data collection. Thematic analysis was used. Four themes were generated, namely initiation of love affairs; dating and sexual behaviour, preferences, pattern and places; phycological, physical and sexual issues and violence related to love affairs and dating behaviour; assistance and advice on issues, problems in love affairs, dating and sexual behaviour. One of the key issues identified was lack of reliable person to seek advice for issues related to love affairs, dating and sexual behaviour among youth. Unmarried youth should be desensitized of the norms that inhibit the communication of love affairs, dating, sexuality and reproduction. Furthermore, a mechanism to identify high risk youth groups: those who have multiple love affairs, youth with inadequate knowledge of STIs, youth with casual sex, victims of sexual harassment need be designed and implemented


Pathogens ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 437
Author(s):  
Hinh Ly

Despite major discoveries made in the last few decades about Lassa fever, there are still many unresolved key issues that hamper the development of effective vaccines and therapies against this deadly disease that is endemic in several West African countries. Some of these issues include the lack of a detailed understanding of the viral and participating host factors in completing the virus life cycle, in mediating disease pathogenesis or protection from disease, and in activating or suppressing host innate and cellular immunity against virus infection, as well as of the animal models required for testing vaccines and therapeutics. This Special Issue is devoted to understanding some of these important issues and to exploring the current status of the research and development in combating Lassa fever.


Author(s):  
Svetlana Malkhazova ◽  
Polina Pestina ◽  
Anna Prasolova ◽  
Dmitry Orlov

In Russia, as in other countries, the problem of emerging natural focal infectious diseases (EIDs) became more acute toward the end of the 20th century. However, the situation in Russia is unknown to foreign readers, while the prevention and control of these diseases require international collaboration. The aim of the study is to provide a medical–geographical assessment of the distribution of the main natural focal EIDs in Russia, as well as to present the approaches used in the country to create aggregate maps of risk assessment. To consider its current status, we determined the most important natural focal EIDs for Russia (tick-borne encephalitis, ixodid tick-borne borrelioses, hemorrhagic fever with renal syndrome, Crimean–Congo hemorrhagic fever, West Nile fever, Astrakhan spotted fever, leptospiroses, and tularemia) and analyzed the patterns of their epidemic manifestation. As a result, a working classification of such infections and a series of maps showing the current situation of EID morbidity in Russia were created. To design an aggregated risk map, we developed an original mapping methodology and recalculated the model disease incidence by taking data from administrative units and adjusting them for natural geographical boundaries (biomes) for European Russia, and then evaluated the risk of infection for separate model diseases and for a set of them. The highest risk rates are confined to the northwest regions of European Russia, the Cis-Urals and the Volga region, which are naturally related to forest biomes, as well as to the southern steppe regions of the interfluves between the Volga and the Don, and the foothills of the North Caucasus.


2019 ◽  
Vol 45 (4) ◽  
pp. 239-243 ◽  
Author(s):  
Jane Johnson ◽  
Chris Degeling

Emerging infectious diseases (EIDs) remain a significant and dynamic threat to the health of individuals and the well-being of communities across the globe. Over the last decade, in response to these threats, increasing scientific consensus has mobilised in support of a One Health (OH) approach so that OH is now widely regarded as the most effective way of addressing EID outbreaks and risks. Given the scientific focus on OH, there is growing interest in the philosophical and ethical dimensions of this approach, and a nascent OH literature is developing in the humanities. One of the key issues raised in this literature concerns ethical frameworks and whether OH merits the development of its very own ethical framework. In this paper, we argue that although the OH approach does not demand a new ethical framework (and that advocates of OH can coherently adhere to this approach while deploying existing ethical frameworks), an OH approach does furnish the theoretical resources to support a novel ethical framework, and there are benefits to developing one that may be lost in its absence. We begin by briefly explaining what an OH approach to the threats posed by EIDs entails before outlining two different ways of construing ethical frameworks. We then show that although on one account of ethical frameworks there is no need for OH to generate its own, there may be advantages for its advocates in doing so.


1983 ◽  
Vol 1983 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Donald Mackay ◽  
Peter G. Wells

ABSTRACT Three key issues must be addressed when deciding on the desirability of using chemical dispersants for mitigating the adverse effects of oil spills: (1) how effective a given dosage of dispersant will be on a given oil slick; (2) how the dispersed oil and dispersant diffuse into the water column, dissolve, volatilize, degrade, and interact with suspended and bottom sediments; and (3) what effects the dissolved and particulate oil and dispersant will have on water column and benthic biota. It is essential that the first two areas (physical and chemical studies) relate closely to the third (biological aspects) in order that bioassay exposure (in terms of concentration of dispersant, classes of and individual hydrocarbons, and duration) addressing the toxicity issue be realistic. Here, we review the current status of a research program which addresses these issues. Under the program, attempts are being made to quantify dispersant effectiveness (including consideration of effectiveness testing using the Mackay-Nadeau-Steelman system for oils which have evaporated and/or formed water-in-oil emulsions to various extents), water column diffusion, and partitioning of specific hydrocarbons among water, oil, and suspended sediment as well as into the atmosphere. A procedure is described which has been used to quantify the acute toxicity of dispersants to copepods and which is being extended to apply also to the toxic contributions of dissolved and particulate oil. Hopefully, by assembling quantitative expressions for effectiveness, behavior, and toxicity, those situations in which dispersion is desirable can be better identified.


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