N-acetylcysteine or trolox derivative mitigate the toxic effects of methanol on the antioxidant system of rat brain

Toxicology ◽  
2000 ◽  
Vol 156 (1) ◽  
pp. 47-55 ◽  
Author(s):  
R Farbiszewski
2018 ◽  
Vol 12 (3) ◽  
pp. 248-255
Author(s):  
K. V. Sarieva ◽  
A. Y. Lyanguzov ◽  
I. I. Zorina ◽  
O. V. Galkina ◽  
O. V. Vetrovoy

1982 ◽  
Vol 51 (1) ◽  
pp. 53-64 ◽  
Author(s):  
Antti Zitting ◽  
Grażyna Szumańska ◽  
Juha Nickels ◽  
Heikki Savolainen

Author(s):  
N. Mamadalieva ◽  
M. Mustafakulov ◽  
T. Saatov

The work was to study the effect of nerve growth factor (NGF) on the parameters of the antioxidant system in the rat brain. From the submandibular salivary glands of male mice, we isolated and purified fractions with nerve growth activity. We study the effect of NGF on the parameters of the antioxidant system – catalase, superoxide dismutase (SOD), and malon dialdehyde (MDA). It was found that the activity of catalase increases at a concentration of NGF of 5 μg, with a further growth of concentration of NGF a decrease in the activity of the enzyme was observed. SOD activity tends to increase at NGF concentrations of 5 and 25 μg. The decrease in the content of MDA is pronounced with the introduction of various concentrations of NGF. Thus, the activity of antioxidant enzymes tends to be restored in the presence of NGF. Neuroprotectors can exhibit therapeutic efficacy of antioxidants in neurodegenerative diseases and ischemic brain damage.


2012 ◽  
Vol 8 (6) ◽  
pp. 555-560 ◽  
Author(s):  
Mehmet Ugur Cevik ◽  
Abdullah Acar ◽  
Halis Tanriverdi ◽  
Sefer Varol ◽  
Adalet Arikanoglu ◽  
...  

1992 ◽  
Vol 29 (5) ◽  
pp. 699-701 ◽  
Author(s):  
A.S. Perumal ◽  
V.B. Gopal ◽  
W.K. Tordzro ◽  
T.B. Cooper ◽  
J.L. Cadet

Sign in / Sign up

Export Citation Format

Share Document