The role of polygalacturonase, PGIP and pectin oligomers in fungal infection

Author(s):  
F. Cervone ◽  
G. De Lorenzo ◽  
B. Aracri ◽  
D. Bellincampi ◽  
C. Caprari ◽  
...  
Keyword(s):  
2014 ◽  
Vol 31 (4) ◽  
pp. 189-193
Author(s):  
T Islam ◽  
SA Azad ◽  
ME Karim ◽  
L Khondker ◽  
K Rahman

A cross sectional study carried out with patients having suspected paranasal sinus (PNS) mass during January 2009 to October 2010 to evaluate the fungal diseases in PNS by computed tomographic(CT) image and comparison of the findings of this modality with histopathological result. Among the total 76 patients, the mean age of the patients was 35.95 ± 18.24 and common complaints of the patients were nasal obstruction (73.7%) and maximum 53.9% patients had PNS mass in maxillary sinuses. Out of all cases 10 were diagnosed as having fungal infection/mass by CT scan and confirmed by histopathological evaluation. Two cases were diagnosed as having fungal infection/mass by CT scan but not confirmed by histopathological findings. Of 64 cases of other than fungal infection/mass, which were diagnosed by CT scan, six were confirmed as having fungal infection/mass and 58 were other than having fungal infection/mass by histopathology. Sensitivity of CT scan to diagnose fungal infection/mass was 62.5%, specificity 96.7%, positive predictive value 83.3%, negative predictive value 90.6% and accuracy 89.5%. CT scan of the fungal diseases in paranasal sinus provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology. DOI: http://dx.doi.org/10.3329/jbcps.v31i4.21002 J Bangladesh Coll Phys Surg 2013; 31: 189-193


2021 ◽  
Vol 8 (4) ◽  
pp. 207-213
Author(s):  
Himanshi Narang ◽  
Amit Patil

The COVID-19 pandemic, which originated from Wuhan, China, has rapidly spread worldwide, including India. As India grappled with the second wave, COVID-triggered fungal infection has suddenly risen tremendously, raising a sense of panic in the country. The fungal infection in COVID-19 includes Mucormycosis and Aspergillosis, as common fungal infections primarily affecting rhino-orbital structures. Many research papers have published postmortem findings in autopsies conducted on COVID-19 decedents, thereby helping to understand this contagious disease's pathogenesis. But, with the arrival of COVID-triggered fungal infection, which is a crucial invasive disease responsible for fatality, very few research papers have commented on the postmortem findings of invasive fungal infections affecting the rhino-orbital and craniocerebral structures in COVID-19 deaths. Therefore, the role of invasive fungal infection due to COVID-19 illness must be established in the causation of deaths in COVID-19 patients. This review research deals with autopsy dissection techniques and possible postmortem findings of invasive fungal infections involving the nasal and paranasal sinuses and orbital structures in COVID-19 deaths. The findings of fungal infection affecting nasal and paranasal systems may not differ in live patients and in a deceased; however, it is essential that correct interpretation of the postmortem findings aided by pre-or post-autopsy investigations is necessary to establish the role of covid triggered fungal infection in such deaths.


2021 ◽  
Vol 27 (1) ◽  
pp. 9-11 ◽  
Author(s):  
Timothy M. Rawson ◽  
Richard C. Wilson ◽  
Alison Holmes
Keyword(s):  

Author(s):  
Prajwal Kumar ◽  
Swati Goyal ◽  
Prashanth Prabhu

Background and Aim: A rare fungal infection, mucormycosis, has become more common in patients recovering from COVID in its second wave in India. The proximity and easy access to the middle ear through the Eustachian tube from paranasal sinuses alarms the need for early detec­tion of middle ear involvement. Hence, the study was carried out to determine the influence of mucormycosis on Immittance and otoacoustic emissions. Methods: eleven rhino orbital mucormycosis patients aged 40-60 years participated in the study. Middle ear evaluation was carried out with the help of Immittance and otoacoustic emissi­ons. Results: It was found that 4/11 (36.36%) parti­cipants had abnormal Immittance and absent oto­acoustic emissions, indicating middle ear dys­function. 3/4 participants had middle ear dys­function in the ear ipsilateral to the side of the infection. Conclusion: The study results reveal a rare cha­nce of middle ear involvement in mucormycosis patients, which calls for the crucial role of the audiologist in the early detection of middle ear dysfunction. Keywords: Mucormycosis; immittance; otoacoustic emissions


2016 ◽  
Vol 10 (3) ◽  
pp. 243
Author(s):  
SaharF Youssif ◽  
AshrafZ Mohamed ◽  
AhmadM Moharrm ◽  
MahaK Ghanem ◽  
HodaA Makhlouf ◽  
...  

2019 ◽  
Vol 104 (8) ◽  
pp. 1036-1036 ◽  
Author(s):  
Tarika Thareja ◽  
Regis Kowalski ◽  
Roheena Kamyar ◽  
Deepinder Dhaliwal ◽  
Bennie H Jeng ◽  
...  

Fungal infection after corneal transplantation is a rare, yet potentially devastating, postoperative complication and has become a growing concern for the transplant surgeon and eye banking community. The Eye Bank Association of America (EBAA) has reported an increasing trend in the rate of postkeratoplasty fungal infections and a reversal in the previously documented predominance of bacterial over fungal infections. Additionally, several studies have confirmed a high correlation between positive corneoscleral donor rim fungal cultures and postoperative infections. Optisol GS (Bausch & Lomb, Irvine, California, USA), the most extensively used corneal storage solution in US eye banks, does not currently contain any antifungal supplementation. Although large randomised control trials evaluating the efficacy and safety of routine antifungal supplementation to corneal storage solution are lacking, several investigative studies have assessed the role of antifungal agents in reducing fungal contamination of donor corneas without causing undue corneal toxicity. This review will present the current epidemiology of postkeratoplasty fungal infections and evidence for obtaining routine fungal rim cultures and antifungal supplementation of storage solution.


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