Body Mass Index and Impaired Fasting Blood Glucose as Predictive Factors of Efficacy in Cetuximab-Based Colorectal Cancer Treatment

Background: Obesity is one of the most important modifiable risk factors in the pathogenesis of lifestyle diseases like atherosclerosis, hypertension and type 2 diabetes mellitus. Overweight or obese adolescents are at an increased risk of developing diabetes and hypertension in future. A study was done to determine the relationship between body mass index and fasting blood glucose among students of a tertiary care teaching hospital. Materials and methods: A cross sectional analytical study was carried out among all medical students in a tertiary care teaching hospital in Kerala who consented to participate after obtaining approval from Institutional Research and Ethics Committee. The study tools used were standardized weighing machine, stadiometer, Accu-check glucometer and strips, disposable needles and pre-designed questionnaire. Results: Among the 254 study participants, 67% were females. The prevalence of impaired fasting glucose is 18.11% in the study population. No significant correlation was found between fasting blood glucose and body mass index. There was an increase in median FBS as the BMI increases, though not statistically significant (p=0.08). In the linear regression model, the statistic R2 explains that 7.9% of the variability in fasting blood glucose is explained by body mass index. Conclusion: The prevalence of prediabetes among the study participants was very high and it was higher among those who were overweight. The need of the hour is to identify the high-risk group in the community right from the young age and initiate trials or intervention studies to prevent or delay the onset of diabetes.

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The Effect of Body Mass Index on Fasting Blood Glucose and Development of Diabetes Mellitus After Initiation of Extended-Release Niacin

Metabolic Syndrome and Related Disorders ◽

10.1089/met.2009.0074 ◽

2010 ◽

Vol 8 (1) ◽

pp. 79-84 ◽

Cited By ~ 5

Author(s):

Ardelle Libby ◽

Joy Meier ◽

Julio Lopez ◽

Arthur L.M. Swislocki ◽

David Siegel

Keyword(s):

Diabetes Mellitus ◽

Body Mass Index ◽

Blood Glucose ◽

Body Mass ◽

Extended Release ◽

Fasting Blood Glucose

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Body Mass Index, Waist Circumference, Body Fat, Fasting Blood Glucose in a Sample of Moroccan Adolescents Aged 11–17 Years

Journal of Nutrition and Metabolism ◽

10.1155/2012/510458 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 11

Author(s):

Slimane Mehdad ◽

Abdeslam Hamrani ◽

Khalid El Kari ◽

Asmaa El Hamdouchi ◽

Amina Barakat ◽

...

Keyword(s):

Body Mass Index ◽

Blood Glucose ◽

Waist Circumference ◽

Body Mass ◽

Body Fat ◽

Significant Relationship ◽

Weight Status ◽

Fasting Blood Glucose ◽

Normal Weight ◽

Screening Tools

Objectives. The study aimed to assess the relationship between body fat and each of body mass index (BMI) and waist circumference (WC), and to test the effectiveness of fat mass (FM), percent of body fat (PBF), BMI, and WC in predicting high levels of fasting blood glucose (FBG).Methods. A total of 167 adolescents aged 11–17 years were recruited from Rabat region. BMI and WC were determined using standard equipments. FM and PBF were derived from isotope dilution technique. FBG was determined by the hexokinase method.Results. Regardless of the weight status, BMI showed a strong positive correlation with FM and PBF in both genders. WC was significantly correlated with FM in boys and girls, and with PBF in different groups of girls and boys of the study sample. However, there was no significant relationship between WC and PBF in normal weight and overweight-obese groups of boys. FBG was highly correlated with FM and PBF in girls of the study sample and in overweight-obese girls. Similar significant relationship between FBG and both BMI and WC was observed in overweight-obese girls, while there was no significant association between FBG and other variables in boys and normal-weight girls.Conclusion. BMI and WC were closely associated with FM and PBF, respectively. However, the degree of these associations depends on gender and weight status. BMI may provide a better proxy estimate of overall adiposity than WC; nevertheless, both of them would appear to be a reasonable surrogate for FM and PBF as screening tools to identify adolescents at risk of developing excess body fat and high level of FBG.

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High-density lipoprotein cholesterol levels increase with age, body mass index, blood pressure and fasting blood glucose in a rural Uygur population in China

Journal of Hypertension ◽

10.1097/01.hjh.0000187254.12375.b6 ◽

2005 ◽

Vol 23 (11) ◽

pp. 1985-1989 ◽

Cited By ~ 5

Author(s):

Weili Yan ◽

Dongfeng Gu ◽

Xiaoyan Yang ◽

Jun Wu ◽

Ling Kang ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Blood Glucose ◽

High Density Lipoprotein ◽

Body Mass ◽

High Density Lipoprotein Cholesterol ◽

Fasting Blood Glucose ◽

Density Lipoprotein ◽

Cholesterol Levels ◽

Uygur Population

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GAMBARAN KADAR GLUKOSA DARAH PUASA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI ANGKATAN 2011 DENGAN INDEKS MASSA TUBUH ≥ 23 kg/m2

Jurnal e-Biomedik ◽

10.35790/ebm.1.1.2013.4362 ◽

2013 ◽

Vol 1 (1) ◽

Author(s):

Gracia Rorong ◽

Stefana Kaligis ◽

Diana Purwanto

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Blood Glucose ◽

Blood Glucose Level ◽

Body Mass ◽

Glucose Level ◽

Fasting Blood Glucose ◽

Fasting Blood Glucose Level ◽

Cross Sectional ◽

Purposive Sampling

Abstract: Glucose is a main compound that has important role in preparation and development of energy in human body. Blood glucose level is the amount of glucose in the blood. One of the factors that affects blood glucose level is body weight. Body weight is affected by several factors, such as aged, gender, and physical activities. Overweight may cause insulin resistance, results in increasing of the blood glucose level. This study aimed to describe the fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2. Research method used for this study was cross sectional descriptive survey with purposive sampling method. From 26 respondents, 12 overweight (BMI ≥23 kg/m2) respondents (46,15%) had average fasting blood glucose level 85,4 mg/dL and 14 obese (BMI ≥25 kg/m2) respondents (53,85%) had average fasting blood glucose level 86 mg/dL. Conclusion: the description of fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2 is at normal level (80-100 mg/dL). Keywords: BMI ≥23 kg/m2, Fasting blood glucose, students year 2011 Abstrak: Glukosa merupakan suatu molekul utama yang berperan penting dalam penyediaan dan pembentukan energi di dalam tubuh. Kadar glukosa darah adalah jumlah kandungan glukosa dalam darah. Salah satu faktor yang mempengaruhi kadar glukosa darah adalah berat badan. Berat badan dipengaruhi oleh beberapa faktor, antara lain usia, jenis kelamin, dan aktivitas fisik. Kelebihan berat badan dapat menyebabkan resistensi insulin sehingga kadar glukosa dalam darah meningkat. Peningkatan kadar glukosa darah merupakan salah satu penanda sindroma metabolik. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 dengan Indeks Massa Tubuh (IMT) ≥23 kg/m2. Jenis penelitian berupa penelitian survey deskriptif cross sectional dengan metode purposive sampling. Sampel penelitian sebanyak 26 orang responden. Hasil penelitian ini didapatkan 12 orang responden (46,15%) yang overweight (IMT ≥23 kg/m2) memiliki rata-rata kadar glukosa darah puasa 85,4 mg/dL dan 14 orang responden (53,85%) yang obesitas (IMT ≥25 kg/m2) memilki rata-rata kadar glukosa darah puasa 86 mg/dL. Simpulan: semua responden mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 memiliki kadar glukosa darah puasa normal (80-100 mg/dL). Kata Kunci: Glukosa darah puasa, IMT ≥23 kg/m2, mahasiswa angkatan 2011

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