Childhood trauma, dissociation in patients with fibromyalgia and rheumatoid arthritis

2011 ◽  
Vol 26 (S2) ◽  
pp. 382-382
Author(s):  
O. Kilic ◽  
O. Taycan ◽  
C. Aksoy Poyraz ◽  
T.C. Erol ◽  
O. Tecer ◽  
...  

IntroductionThe contribution of childhood trauma and dissociation to the unknown pathophysiology of fibromyalgia has been the subject of considerable debate.ObjectivesTo assess and compare the relationship of childhood trauma and somatoform dissociation between patients with fibromyalgia and rheumatoid arthritis both of which are characterized by chronic pain and disability.AimsEarly life and prolonged trauma may affect brain modulatory circuitry of pain and emotions. The findings of relationship between traumatic events, dissociation and fibromyalgia can lead to a better understanding of the etiology and suggest new treatment modalities.MethodsThirty-one patients with fibromyalgia and 19 patients with rheumatoid arthritis were enrolled in the study. All participants were asked to fill in the Childhood Trauma Questionnaire, Somatoform Dissociation Questionnaire and Dissociation Questionnaire.ResultsPhysical neglect score was higher in fibromyalgia group than rheumatoid arthritis group (p < 0.05) although there was no significant difference between two groups in other subscores of childhood trauma and the rest of the dissociation scores. Total trauma scores were positively correlated with dissociation scores in fibromyalgia group whereas this correlation was not seen in rheumatoid group.ConclusionsAmong childhood trauma types, physical neglect seems to have a more important role in fibromyalgia than rheumatoid arthritis. Fibromyalgia may be related to early life stress or prolonged trauma, affecting brain modulatory circuitry of pain and emotions in genetically susceptible individuals.

Author(s):  
Xue Dong ◽  
Fang Su ◽  
JiaYu Du ◽  
Yahua Hu ◽  
ZhengHong Wang

Objective Parents’ labor migration has resulted in a great quantity of Left Behind Adolescents (LBA) in China. This study aims to examine if childhood trauma and internet addiction does predict depression on LBA in comparison to Non-Left Behind Adolescents (NLBA) in China. Methods Participants in the study includes a sample of 1890 adolescents aged 12 to 27, including 102 LBA and 1399 NLBA in China. All participants completed the self-report questionnaires, Childhood Trauma Questionnaire (CTQ-28), Internet Addiction Test (IAT), and the Beck Depression Inventory (BDI). Results There was a significant difference in IAT and CTQ between LBA and NLBA (P < 0.05). The frequent childhood trauma type was physical neglect (48%), followed by emotional neglect (32.3%). Males reported higher levels of emotional and physical abuse and physical neglect than female counterparts in LBA. The prevalence of depression (23.5%) and internet addiction (29.4%) were higher among LBA than NLBA. There were no significant differences in depression (p > 0.05). There were positive correlations between CTQ (except emotional neglect), BDI, and IAT. Multiple linear regressions indicated that emotional abuse and neglect, internet addiction, and poor academic performance were significant predictors for depression among LBA. Conclusion Childhood trauma and internet addiction were directly related to symptoms of depression in LBA, There is an urgent need for targeted interventions for LBA to prevent negative mental health outcomes.


2021 ◽  
Author(s):  
Chuanyue Wang ◽  
Zhen Mao ◽  
Feng Li ◽  
Fan He ◽  
Fang Dong ◽  
...  

Abstract Objectives: This study is aimed to examine the potential association between childhood trauma (CT) and personality traits among unaffected first-degree relatives (FDR, children or siblings of patients) of patients with major depressive disorder (MDD). Methods: The study consists of three groups: total 85 patients with MDD, 35 FDRs and 89 healthy control individuals (HC). The Childhood Trauma Questionnaire (CTQ) was used to assess childhood trauma and the Eysenck Personality Questionnaire used to assess personality traits. Results: By comparison made in personality traits, MDD patients exhibits some significant disparities to FDR and HC (p<0.05 for extraversion, neuroticism and psychoticism). Nevertheless, no significant difference was found between HC and FDR. In FDR group, patients with CT scored noticeably higher for neuroticism (N) compared with those without CT (F=3.246, p=0.046). CT was associated with N, psychoticism (P) and Lie (L), and it was associated with N more closely (r=0.290-0.452, p<0.05 for all). Significantly positive correlations were found between N and sexual abuse (SA), emotional neglect (EN), physical neglect (PN), and CTQ total (r=0.344-0.452, p<0.05); P and CTQ (r=0.336, p<0.05); and significant negative correlations between L and EN, CTQ (r=-0.446-0.375, p<0.05). EN contributed to a probability of N, P (R2=0.155-0.214, F=6.066-9.010, p=0.005-0.019) as well as a probability of L (R2=0.199, F=8.211, p=0.007). Conclusion: CT was associated with N, P and L, with a closer relation to N in unaffected FDR. Besides, the type of CT, the most relevant to N, was discovered to be EN. Thus, FDR of MDD who experienced CT should be prioritized. Key words: childhood trauma; personality; major depressive disorder; first-degree relatives


2021 ◽  
Vol 12 ◽  
Author(s):  
Artjom Frick ◽  
Isabel Thinnes ◽  
Stefan G. Hofmann ◽  
Sabine Windmann ◽  
Ulrich Stangier

Reduced social functioning in depression has been explained by different factors. Reduced social connectedness and prosocial motivation may contribute to interpersonal difficulties, particularly in chronic depression. In the present study, we tested whether social connectedness and prosocial motivation are reduced in chronic depression. Forty-seven patients with persistent depression and 49 healthy controls matched for age and gender completed the Inclusion of the Other in the Self Scale (IOS), the Compassionate Love Scale (CLS), the Beck Depression Inventory-II, and the Childhood Trauma Questionnaire. A Multivariate analysis of variance (MANOVA) with IOS and CLS as dependent variables revealed a highly significant difference between both groups. The IOS and the CLS-subscale Close Others were lower in persistent depression, whereas there was no difference in the CLS-subscale Strangers/Humanity. IOS and CLS-Close Others showed significant negative correlations with depressive symptoms. Connectedness to family members as measured by the IOS was negatively correlated with childhood trauma in patients with chronic depression. The results indicate that compassion and perceived social connection are reduced in depressed patients toward close others, but not to others in general. Implications for the treatment of depression are discussed.


2017 ◽  
Vol 41 (S1) ◽  
pp. s852-s853
Author(s):  
G. Teksin Unal ◽  
O. Sahmelikoglu Onur ◽  
C. Karsidag ◽  
M.G. Teksin Bakir

IntroductionSexual dysfunction (SD) is defined as the deterioration of sexual response cycles caused by anatomic, physiologic or psychologic reasons.ObjectivesWe believe that SD is closely related to self-esteem and childhood trauma (CT).AimIn this study, the level of self-esteem and CT in patients diagnosed with SD vs. controls are aimed to be compared. In addition, relationship between complaints of SD self-esteem and CT variable subgroups are planned to be investigated.MethodTwenty-four patients visited Prof. Dr. Mazhar Osman Psychiatric Hospital with matching defined criteria and 24 control counterparts statistically matching were taken sociodemographic data form, Rosenberg Self-esteem Scale (RSS) and Childhood Trauma Questionnaire (CTQ-28) was applied.ResultsCTQ-28 averages and RSS variables which are sensitivity to criticism, depressive mood, psychosomatic symptoms, feeling threatened in interpersonal relationships, degree to participate in discussions, relationship with father were higher in patients with SD (P < 0.05). Considering the relationship between complaints of SD and CTQ-28 subscales, physical abuse, emotional abuse, physical neglect, emotional neglect averages of patients were observed significantly different rooted by genitopelvic pain/penetration disorder and premature ejaculation and in emotional neglect by premature ejaculation and low libido combination (P < 0.05).ConclusionsIn literature, there are many studies that show CT leads to SD and several studies state that self-esteem is affected in patients with SD [1]. CT must be considered and determined in the goal of treatment of SD.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2016 ◽  
Vol 33 (S1) ◽  
pp. s241-s241
Author(s):  
A. Arous ◽  
R. Trabelsi ◽  
J. Mrizak ◽  
A. Aissa ◽  
H. Ben Ammar ◽  
...  

IntroductionEmpathy, which refers to the ability to understand and share the thoughts and feelings of others, has emerged as an important topic in the field of social neuroscience. It is one of the most understudied dimensions of social cognition in schizophrenia (SCZ).ObjectivesTo investigate the relationship between cognitive and affective empathy and CT in SCZ.MethodsFifty-eight outpatients with stable SCZ completed the Childhood Trauma Questionnaire retrospectively assessing five types of childhood trauma (emotional, physical and sexual abuse, and emotional and physical neglect). They also completed the Questionnaire of Cognitive and Affective Empathy (QCAE) comprising five subscales intended to assess cognitive and affective components of empathy.ResultsPatients with a history of sexual abuse better emotion contagion scores (P = 0.048) which means that develop more easily self-oriented emotional state matching the affective states of others. Patients with a history of emotional neglect or/and in denial of CT had higher scores in perspective taking score (P = 0.017). Perspective taking assesses the extent to which respondents can take another's perspective or see things from another's point-of-view.ConclusionsInvestigating psychosocial mechanisms, specifically the role of CT, underlying the development of empathic capacities is important since empathy can represent a treatment-target.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2018 ◽  
Vol 30 (3) ◽  
pp. 971-980 ◽  
Author(s):  
Michael Deuschle ◽  
Ferdinand Hendlmeier ◽  
Stephanie Witt ◽  
Marcella Rietschel ◽  
Maria Gilles ◽  
...  

AbstractThe prenatal environment shapes the offspring's phenotype; moreover, transgenerational stress and stress during pregnancy may play a role. Brain-derived neurotrophic factor (BDNF) and glucocorticoids influence neurodevelopment during pregnancy, and there is evidence that BDNF in amniotic fluid is mainly of fetal origin, while the source of glucocorticoids is maternal. We tested the hypothesis that maternal early life stress, psychiatric diagnoses, anxiety, perceived stress, and socioeconomic status influence BDNF and glucocorticoid concentrations in amniotic fluid in the second trimester. We studied 79 pregnant women who underwent amniocentesis in the early second trimester and analyzed BDNF, cortisol, and cortisone concentrations in amniotic fluid. The endocrine data were related to maternal early life adversities (Childhood Trauma Questionaire), perceived stress (Perceived Stress Scale), anxiety, socioeconomic status (family income), and the presence of psychiatric diseases. We found BDNF in amniotic fluid to be positively related to maternal early adversity (Childhood Trauma Questionaire). Low family income (socioeconomic status) was related to high amniotic fluid glucocorticoid concentrations. Neither glucocorticoid concentrations nor hydroxy steroid dehydrogenase (HSD2) activity could be related to BDNF concentrations in amniotic fluid. Early maternal adverse events may be reflected in the fetal BDNF regulation, and it should be tested whether this relates to differences in neurodevelopment.


2016 ◽  
Vol 33 (S1) ◽  
pp. S372-S372 ◽  
Author(s):  
J. Mrizak ◽  
A. Arous ◽  
R. Trabelsi ◽  
A. Aissa ◽  
H. Ben Ammar ◽  
...  

IntroductionThe impairment of facial emotion recognition (FER) among patients with schizophrenia (SCZ) is a significant feature of the illness. Childhood trauma (CT) is reported with a high prevalence in SCZ and is considered one of its risk factors.ObjectivesTo investigate the relationship between FER and CT in SCZ.MethodsFifty-eight outpatients with stable SCZ completed the Childhood Trauma Questionnaire retrospectively assessing five types of childhood trauma (emotional, physical and sexual abuse, and emotional and physical neglect). They also completed a newly developed and validated FER task constructed from photographs of the face of a famous Tunisian actress and evaluating the ability to correctly identify Ekman's six basic facial emotions (happiness, sadness, anger, disgust, fear and surprise).ResultsPatients with higher scores of CT performed significantly worse in FER task. Our results suggest that the presence of sexual abuse is specifically correlated to a poor identification of anger (P = 0.02) and disgust (P = 0.03) while the presence of emotional abuse and physical neglect are correlated to a poor identification of happiness and sadness.ConclusionsCT may represent one of the causes of the FER deficits in schizophrenia. Further studies are necessary to confirm the link between specific kinds of childhood trauma and deficits in the recognition of discrete emotions.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2021 ◽  
Author(s):  
Hongwei Zhang ◽  
Ziqi Liu ◽  
Hui Zheng ◽  
Ting Xu ◽  
Lin Liu ◽  
...  

Abstract Background: Early life stress induces long-lasting changes in adulthood, such as psychiatric and metabolism abnormality. The prevalence of childhood emotional abuse in clinical obese subjects remains unclear.Method: A set of questionnaires, including the Childhood Trauma Questionnaire (CTQ), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and Eating Disorder Inventory (EDI) was sent out. Clinical data from 37 obese subjects (Age: 29.65±5.35, Body Mass Index (BMI): 37.59±6.34) and 37 healthy subjects with normal body weight (Age: 31.35±10.84, BMI: 22.16±3.69) came into the investigation. Multiple mediation analysis was performed with BMI as the outcome variable, childhood trauma as the predictive variable. Depression, anxiety, and bulimia as the mediating variables.Result: Obese group reported higher childhood emotional abuse (t=2.157, p=0.034), worse mood state (anxiety: t=5.466, p<0.001; depression: t=2.220, p=0.030), and increased bulimia (t=3.400, p=0.001), when compared to healthy group. Childhood emotional abuse was positively associated with BMI (β = 1.312, 95% CI = 0.482−2.141). Anxiety and bulimia showed multiple mediating roles in the relationship of childhood emotional abuse and obesity (indirect effect = 0.739, 95% CI = 0.261−1.608), accounting for 56.33% of the total effect.Conclusion: Childhood emotional abuse may contribute to adulthood obesity, potentially mediated by anxiety and bulimia.


2019 ◽  
Vol 12 (1) ◽  
pp. 30-40
Author(s):  
Eglantina Dervishi ◽  
Elisabeta Mujaj ◽  
Silva Ibrahimi

The aim of this study was the exploration of early traumatic experiences related to emotional abuse, physical abuse, sexual abuse, emotional and physical neglect, as well as the connection of the dimensions of these early traumatic experiences with the experiencing of depressive symptoms in adulthood. A sample of 331 University students in Tirana, 60 males (N = 60) or 18.1% and 271 females (N = 271) or 81.9% completed the online Beck Inventory for Depression (BDI), and the Childhood Trauma Questionnaire-Short Form (CTQ-SF). The minimum age of the youth participating in the study was 18 years and the maximum age was 32 years, with an average of 20 years (M = 20.07) and the standard deviation (SD = 1.5). Descriptive, correlational and linear regression analysis were used for data processing through the SPSS 22. The study confirmed the connection between early traumatic experiences and the appearance of depressive symptoms in adulthood (r(329) = .333, p < .001). Among the dimensions of early traumatic experiences, it seems that a stronger connection with the occurrence of depressive symptoms relates to the size of emotional trauma. The size of child sexual trauma is connected to feelings of punishment and suicidal thoughts in adulthood. Early traumatic experiences seem to have a significant impact on how adults express themselves and choose to interact with their environment. Coping with problems of mental health and depression today can be closely related to the early traumatic experiences of juveniles and adults.


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