The effect of family psychoeducational interventions on patients with depression

2011 ◽  
Vol 26 (S2) ◽  
pp. 2209-2209 ◽  
Author(s):  
A. Fiorillo ◽  
C. Malangone ◽  
V. Del Vecchio ◽  
C. De Rosa ◽  
M. Luciano ◽  
...  

While the efficacy of family psychoeducational interventions in the treatment of schizophrenia is now well documented, few data are available on its efficacy in major depression. This study aimed to verify the effectiveness of a family psychoeducational intervention according to the Falloon model on patients’ clinical status, social functioning and lifestyle and on relatives’ burden and social network.The study was coordinated by the Department of Psychiatry of the University of Naples SUN and carried out in 7 Italian mental health centres. In each centre, 8 patients with major depression and their relatives were recruited if they fulfilled the following criteria: a) diagnosis of unipolar major depression according to the DSM-IV; b) aged between 18 and 65 years; c) in charge to the local mental health centre for at least 6 months; d) at least one depressive episode in the last two years; e) living with at least one relative aged between 18 and 70 years.Recruited families have been randomly allocated to the experimental group, which received the psychoducational intervention for 6 months, or to the control group, which received the treatment as usual plus an informative brief intervention.22 families have been treated with the experimental intervention and 22 with the control one. At the end of the intervention, patients’ clinical status and life-style significantly improved in the treated group, as well as family objective burden and social contacts.Family psychoeducational intervention are useful in reducing personal and family difficulties caused by depression and in improving patients’ lifestyles.

Author(s):  
Tânia Morgado ◽  
Luís Loureiro ◽  
Maria Antónia Rebelo Botelho ◽  
Maria Isabel Marques ◽  
José Ramón Martínez-Riera ◽  
...  

Adolescence is a critical life phase for mental health and anxiety an emerging challenge for adolescents. Psychoeducational interventions to promote mental health literacy (MHL) on anxiety in adolescents are needed. This study aimed to test the primary outcome of a future full-scale trial: improvement of adolescents’ anxiety MHL components on recognition, prevention strategies, and self-help strategies. A sample of 38 adolescents, 24 (63.2%) females and 14 (36.8%) males, with an average age of 14.50 years (SD = 0.89) participated in this study. Each class was allocated to the intervention group (IG, n = 21) or the waiting list control group (WLCG, n = 17) with single-blinded randomization. MHL was assessed using the QuALiSMental. The ProLiSMental psychoeducational intervention consists of four or eight weekly sessions of 90 or 45 min for adolescents, using different active pedagogical methods and techniques. There also are initial and final sessions with adolescents, legal guardians, and teachers. There was a significant improvement with a small to relatively strong effect size in many dimensions of anxiety MHL components. This study suggests the progression to the full-scale trial and values the important role of mental health and psychiatric nurses in the adolescents’ empowerment for MHL in schools.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zsofia P. Cohen ◽  
Kelly T. Cosgrove ◽  
Elisabeth Akeman ◽  
Sara Coffey ◽  
Kent Teague ◽  
...  

Abstract Background Early life stress (ELS) has been linked to poor mental and physical health outcomes in adolescence and adulthood. Mindfulness reduces symptoms of depression and anxiety and improves cognitive and social outcomes in both youth and adults. However, little is known whether mindfulness can mitigate against the adverse neurobiological and psychological effects of ELS. This study aimed to examine the feasibility of conducting a group mindfulness intervention in adolescents with ELS and provide preliminary indication of potential effects on stress-related biomarkers and mental health symptoms. Methods Forty adolescents were randomized to receive either eight sessions of Mindfulness-Based Stress Reduction for Teens in group format (MBSR-T; n = 21) or Treatment as Usual Control group (CTRL; n = 17). Outcomes were assessed at baseline and follow-up and included measures associated with neurobiological functioning (immune and endocrine biomarkers) and self-reported mental health (depressive) symptoms. Linear mixed effects models were used to assess the effects of group and time on these outcome measures. Results Sixteen of the 21 adolescents completed the intervention, attending an average of 6.5 sessions. The model examining cortisol responses to stress induction revealed medium effects trending toward significance (Cohen’s d = .56) for anticipatory cortisol levels in the MBSR-T relative to CTRL groups. No significant effects were found in models examining C-reactive protein or interleukin 6 inflammatory markers. The model examining depressive symptoms revealed a medium effect for symptom reduction (Cohen’s d = .69) in the MBSR-T relative to CTRL groups. Conclusions This study demonstrated feasibility of conducting a group-based MBSR-T intervention for adolescents with ELS. There was some evidence for efficacy on a symptom level with potential subtle changes on a biological level. Future larger studies are needed to determine the efficacy of group-based mindfulness interventions in this population. Trial registration Identifier #NCT03633903, registered 16/08/2018.


2020 ◽  
Author(s):  
Justus Tönnies ◽  
Mechthild Hartmann ◽  
Michel Wensing ◽  
Joachim Szecsenyi ◽  
Frank Peters-Klimm ◽  
...  

BACKGROUND Most people suffering from depression and anxiety disorders are solely treated by their primary care physician. Access to specialized mental health care is impeded by patients’ comorbidity and immobility in ageing societies and long waiting times on the providers’ end. Video-based integrated care models may leverage limited resources more efficiently and provide timely specialized care in the primary care environment the patient is already familiar with. OBJECTIVE In an individually randomized controlled trial we aimed to evaluate the feasibility of mental health specialist video consultations with primary care patients with depression and/or anxiety disorder. METHODS Participants were recruited by their primary care physicians during regular practice visits. Eligible patients were required to experience at least moderate symptoms of depression and/or anxiety disorder. Patients were randomized in two groups receiving either treatment as usual as provided by their general practitioner or up to five video consultations conducted by a mental health specialist. Video consultations focused on (1) systematic diagnosis plus proactive monitoring using validated clinical rating scales, (2) the establishment of an effective working alliance and (3) a stepped-care algorithm within integrated care adjusting treatments based on clinical outcomes. Feasibility outcomes were recruitment, rate of loss to follow-up, acceptability of treatment and attendance at sessions. Effectiveness outcomes included depression (PHQ-9), anxiety (GAD-7), burden of specific somatic complaints (Somatic Symptom Disorder-B Criteria Scale, SSD-12), recovery (Recovery Assessment Scale, RAS-G), and perception of chronic illness care (Patient Assessment of Chronic Illness Care, PACIC–Short Form) – which were measured at baseline and 16 weeks post-allocation by assessors blinded to group allocation. RESULTS Fifty patients with depression and/or anxiety disorder were randomized, 23 to the intervention group and 27 to the treatment-as-usual group. The recruitment yield (number randomized per number screened) and consent rate (number randomized per number eligible) were 50/73 (68.5%) and 50/58 (86.2%), respectively. Concerning acceptability, 20 (87.0%) of the 23 in the intervention group completed the intervention. Of 108 planned video consultations, 102 (94.4%) were delivered. Follow-up rates were 95.7% and 85.2% for the intervention and the control group, respectively. Change from baseline scores at post-measurement for the “No Domination by Symptoms” domain of recovery (RAS-G) were somewhat higher for the intervention group compared to the control group (Mann-Whitney U-Test: rank-biserial r = 0.19 [-0.09; 0.46], P = .18). We did not detect any notable differences between the intervention group and the control group for the other effectiveness outcomes. We did not observe any serious adverse events related to the trial. CONCLUSIONS The intervention and study procedures are feasible for patients, primary care practice staff, and mental health specialists. A sufficiently powered pragmatic trial on mental health specialist video consultations should be conducted to investigate effectiveness in routine care. CLINICALTRIAL German Clinical Trials Register (registration no. DRKS00015812).


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Hongyan Xu ◽  
Qiao Teng ◽  
Yan Zeng ◽  
Chunping Tian ◽  
Bowen Yang ◽  
...  

Objectives. Systemic lupus erythematosus (SLE) is a complex and relapsing autoimmune disease and worsens the quality of life (QOL) of patients by affecting their physical and psychological status. The effectiveness of psychoeducational interventions on patients with active SLE was investigated. Methods. Eight-five patients with active SLE were randomly assigned to an observation group or a control group; patients in the observation group received psychoeducational interventions. The following variables were evaluated within a week after admission, 3 and 6 months after psychoeducational intervention: the World Health Organization Quality of Life Instrument- (WHOQOL-) BREF scores, the Medical Outcomes Study Short Form 36 (SF-36) scores, the Beck Depression Inventory, and Spielberger’s State-Trait Anxiety Inventory (STAI). Results. We found that scores of all four domains of the WHOQOL-BREF scale were remarkably increased 3 months after psychoeducational intervention in the intervention group and significantly higher than the control group ( P < 0.05 ); 6 months after psychoeducational intervention, psychological and social domain scores of the WHOQOL-BREF scale were remarkably higher in the intervention group than those in the control group, while other scores of three domains were not. PF, RP, BP, GH, RE, and MH scores of the SF-36 scale were remarkably increased 3 months after psychoeducational intervention in the intervention group rather than VT and SF, while all scores of subscales were notably higher in the intervention group than those in the control group ( P < 0.05 ). Six months after psychoeducational intervention, PF, RP, BP, GH, and RE scores of the SF-36 scale were remarkably higher in the intervention group than those in the control group, while VT, SF, and MH scores were not. Three months after psychoeducational intervention, the levels of depression and anxiety of SLE patients were reduced and significantly lower than those in the control group ( P < 0.05 ). Six months after psychoeducational intervention, the level of depression was still reduced, while the level of anxiety was not. Compared with the control group, the levels of depression and anxiety of SLE patients were remarkably declined in the observation group 6 months after psychoeducational intervention ( P < 0.05 ). Conclusion. These data suggest psychoeducational interventions can significantly improve and maintain the QOL of patients with active SLE.


1996 ◽  
Vol 84 (4) ◽  
pp. 629-633 ◽  
Author(s):  
Roberto A. Suastegui Roman ◽  
José Luis Soto-Hernández ◽  
Julio Sotelo

✓ In a prospective open study, 15 patients with hydrocephalus secondary to cysticercosis who required insertion of a ventriculoperitoneal (VP) shunt were treated with 50 mg of prednisone given orally three times a week. Treatment began in the 1st postoperative week, with isoniazid and pyridoxine administered daily as antituberculous chemoprophylaxis. The drug regimen was continued with close follow up for 24 months. Clinical status, Karnofsky performance status (KPS) scores, and postoperative course in the prednisone-treated group were compared with 30 control patients with hydrocephalus due to cysticercosis. The control patients were matched by age and sex, underwent surgical shunting in the same period, and were followed routinely by the neurosurgery staff. Lumbar cerebrospinal fluid (CSF) was studied at 2, 16, and 32 weeks postoperatively in the prednisone group. At 24-month follow up two (13%) of 15 patients in the prednisone group and 18 (60%) of 30 patients in the control group required surgical shunt revisions for symptomatic shunt obstruction (p = 0.002). Follow-up studies of CSF performed at 32 weeks in the prednisone group revealed improvement of abnormal values with statistically significant differences for glucose (p < 0.02). Serial imaging studies in the prednisone group revealed persistence of cysticercal cysts with no change in size. Mean initial KPS scores were similar in both groups. At the end of the follow-up period, the mean KPS score was significantly higher in the prednisone group (p = 0.003). Prednisone and chemoprophylactic drugs were well tolerated. These results suggest that in selected patients with hydrocephalus secondary to cysticercosis, intermittent long-term prednisone therapy after VP shunting may reduce shunt malfunction and improve the functional status of the patients.


2010 ◽  
Vol 13 (3) ◽  
pp. 167-173
Author(s):  
Hapsah Hapsah ◽  
Achir Yani S. Hamid ◽  
Herni Susanti

AbstrakPerempuan paruh baya mengalami banyak perubahan psikososial yang dapat mempengaruhi perkembangannya sehingga diperlukan upaya promotif untuk meningkatkan derajat kesehatannya. Penelitian quasi experimental dengan pendekatan prepost test with control group ini ditujukan untuk mengidentifikasi pengaruh terapi kelompok terapeutik (TKT) terhadap perkembangan generativitas perempuan paruh baya di Kabupaten Pinrang. Hasil penelitian terhadap 34 orang kelompok intervensi dan 36 orang kelompok kontrol (melalui purposive sampling) menunjukkan peningkatan generativitas secara bermakna (p= 0,000, α= 0,05) pada kelompok intervensi dan peningkatan secara tidak bermakna pada kelompok kontrol (p= 0,410, α= 0,05) sebelum dan sesudah dilakukan TKT. Terapi kelompok terapeutik ini direkomendasikan untuk dikembangkan sebagai bentuk pelayanan kesehatan jiwa bagi perempuan paruh baya. AbstractMiddle age women generally experience many phsycosocial changes that can influence their developments, hence they need promoted actions to improve their health quality. This experimental quasi research using pre-post test with control group aims to identify an influence of therapeutic group therapy on the generativity development of middle age women in Pinrang Regency. The results showed that generativity development are significantly higher (p= 0,000, α= 0,05) on treated group (n=34) compared to control group (n=36) which did not show significant improvement (p= 0,410, α= 0,05) before and after intervention. This therapeutic group treatment was recommended to be developed as one way to promote mental health for middle age women.


2021 ◽  
Author(s):  
Zsofia Cohen ◽  
Kelly Cosgrove ◽  
Elisabeth Akeman ◽  
Sara Coffey ◽  
Kent Teague ◽  
...  

Abstract Background: Early life stress (ELS) has been linked to poor mental and physical health outcomes in adolescence and adulthood. Mindfulness reduces symptoms of depression and anxiety and improves cognitive and social outcomes in both youth and adults. However, little is known whether mindfulness can mitigate against the adverse neurobiological and psychological effects of ELS. This study aimed to examine the feasibility of conducting a group mindfulness intervention in adolescents with ELS and provide preliminary indication of potential effects on stress-related biomarkers and mental health symptoms.Methods: Forty adolescents were randomized to receive either eight sessions of Mindfulness- Based Stress Reduction for Teens in group format (MBSR-T; n = 21) or Treatment as Usual Control group (CTRL; n = 17). Outcomes were assessed at baseline and follow-up and included measures associated with neurobiological functioning (immune and endocrine biomarkers) and self-reported mental health (depressive) symptoms. Linear mixed effects models were used to assess the effects of group and time on these outcome measures.Results: Sixteen of the 21 adolescents completed the intervention, attending an average of 6.5 sessions. The model examining cortisol responses to stress induction revealed medium effects trending toward significance (Cohen’s d = .56) for anticipatory cortisol levels in the MBSR-T relative to CTRL groups. No significant effects were found in models examining C-reactive protein or interleukin 6 inflammatory markers. The model examining depressive symptoms revealed a medium effect for symptom reduction (Cohen’s d = .69) in the MBSR-T relative to CTRL groups. Conclusions: This study demonstrated feasibility of conducting a group-based MBSR intervention for adolescents with ELS. There was some evidence for efficacy on a symptom level 73 with potential subtle changes on a biological level. Future larger studies are needed to determine 74 the efficacy of group-based mindfulness interventions in this population.Trial Registration: www.ClinicalTrials.gov, identifier #NCT03633903, registered 16/08/2018.


2011 ◽  
Vol 198 (5) ◽  
pp. 385-390 ◽  
Author(s):  
Kae Shimazu ◽  
Shinji Shimodera ◽  
Yoshio Mino ◽  
Atsushi Nishida ◽  
Naoto Kamimura ◽  
...  

BackgroundThe value of family psychoeducation for schizophrenia has been well established, and indications for its use have recently expanded to include bipolar affective disorder. However, no study to date has adequately examined its use in depression.AimsTo examine family psychoeducation in the maintenance treatment of depression and to investigate the influence of the family's expressed emotion (EE) on its effectiveness.MethodOf 103 patients diagnosed with major depression and their primary family members, 57 pairs provided written informed consent. The pairs were randomly allocated to the intervention (n = 25) or control (n = 32). One family in the intervention group and two in the control group withdrew their consent after randomisation. The intervention group underwent four psychoeducation sessions consisting of didactic lectures about depression and group problem-solving focusing on how to cope in high-EE situations. Patients did not attend these sessions. Patients in both the intervention and control groups received treatment as usual. The families' EE levels were evaluated through Five-Minute Speech Samples. The primary outcome was relapse.ResultsTime to relapse was statistically significantly longer in the psychoeducation group than in the control group (Kaplan–Meier survival analysis, P = 0.002). The relapse rates up to the 9-month follow-up were 8% and 50% respectively (risk ratio 0.17, 95% CI 0.04–0.66; number needed to treat 2.4, 95% CI 1.6–4.9). In Cox proportional hazard analysis, baseline EE did not moderate the effectiveness of the intervention.ConclusionsFamily psychoeducation is effective in the prevention of relapse in adult patients with major depression.


2018 ◽  
Vol 10 (1) ◽  
pp. 58-67 ◽  
Author(s):  
Charles R Jonassaint ◽  
Chaeryon Kang ◽  
Kemar V Prussien ◽  
Janet Yarboi ◽  
Maureen S Sanger ◽  
...  

Abstract Sickle cell disease (SCD) is a severe hemoglobinopathy characterized by acute and chronic pain. Sufferers of the disease, most of whom are underrepresented minorities, are at increased risk for mental health disorders. The purpose of this study is to test the acceptability and implementation of a computerized cognitive behavioral therapy (cCBT) intervention, Beating the Blues, to improve depression, anxiety, and pain in patients with SCD. Adults with SCD and significant symptoms of depression (Patient Health Questionnaire [PHQ-9] score ≥ 10) or anxiety (Generalized Anxiety Disorder Scale [GAD-7] score ≥ 10) were eligible to participate and be randomized to either receive eight sessions of cCBT with care coach support or treatment as usual. Participants reported daily pain and mood symptoms using a mobile diary app. Depression, anxiety, and pain symptoms were assessed at 1, 3, and 6 months. Thirty patients were enrolled: 18 to cCBT, and 12 to control. The cCBT intervention was feasible to implement in clinical settings and acceptable to participants. Patients in the cCBT arm reported a marginally greater decrease in depression at 6 months (−3.82, SE = 1.30) than those in the control group (−0.50, SE = 1.60; p = .06). There were no significant effects of treatment on anxiety; however, cCBT was associated with improved daily pain reported via a mobile diary app (p = .014). cCBT, delivered via mobile device, is a feasible strategy to provide mental health care to adults living with SCD. cCBT was acceptable to the target population; was able to be implemented in real-world, nonideal conditions; and has the potential to improve patient-reported outcomes.


2010 ◽  
Vol 57 (6) ◽  
pp. 596-603 ◽  
Author(s):  
Andrea Fiorillo ◽  
Mariano Bassi ◽  
Giovanni de Girolamo ◽  
Francesco Catapano ◽  
Fabio Romeo

Background: The opinions of relatives of patients with schizophrenia about this disorder can influence its course and outcome. Aims: In 2003, the Italian Psychiatric Association promoted a study on family psychoeducational intervention to explore its effectiveness in improving relatives’ opinions and beliefs about schizophrenia. Methods: In each of the 10 Italian mental health centres, 30 patients with schizophrenia and 30 key relatives were randomly recruited to receive the experimental intervention or the standard care. The experimental intervention consisted of 12 manual-based informative sessions on schizophrenia. Each relative filled in the self-reported questionnaire on family opinions about schizophrenia. Results: The treated sample included 107 patients and 112 relatives; the control group consisted of 105 patients and 118 relatives. In both groups, stress, traumas, heredity and family difficulties were most frequently mentioned as causing the disorder. Relatives’ opinions about patients’ civil rights and social competence, in particular the right to get married, to have children and to vote, improved and the belief that patients with schizophrenia are unpredictable decreased at the end of the intervention. Conclusions: These results confirm that relatives of patients with schizophrenia should receive psychoeducational interventions, particularly in Italy where family involvement in schizophrenia care is particularly frequent.


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