PCN2 THE FREQUENCY OF OCCURRENCE OF SECONDARY MALIGNANT TUMORS EVOLVING ON THE FIELD OF PRIMARY BREAST CANCER IN THE FEMALE POPULATION OF HUNGARY BETWEEN 2003 AND 2007

Accessory breast tissue (ABT) is found in approximately 2%–6% of the female population and are subject to most of the physiological and pathological changes that occur in pectoral breast. Primary breast cancer occurring in ABT is a rare occurrence and a second primary breast cancer occurring in an accessory breast has never been reported. We report the case of a 60-year-old woman with a history of mastectomy for left breast cancer 5 years prior to presentation, who presented with an enlarging right axilla mass found to be a second primary breast cancer in an accessory tissue on biopsy. Many physicians are unfamiliar with the clinical presentation of accessory breast cancer due to the rarity of the condition and this ultimately results in delayed diagnosis and advanced disease at presentation. It is therefore prudent that physicians have a high index of suspicion when patients present with axillary masses.

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THE MORBIDITY OF MAMMARY GLAND CANCER OF FEMALE POPULATION OF THE SIBERIAN FEDERAL DISTRICT

Health Care of the Russian Federation ◽

10.18821/0044-197x-2017-61-3-123-128 ◽

2019 ◽

Vol 61 (3) ◽

pp. 123-128

Author(s):

Irina N. Odintsova ◽

L. F. Pisareva ◽

O. A. Ananina ◽

E. V. Panferova

Keyword(s):

Breast Cancer ◽

Mammary Gland ◽

Birth Rate ◽

Malignant Tumors ◽

Divorce Rate ◽

Federal District ◽

Demographic Characteristics ◽

Siberian Federal District ◽

Female Population ◽

Mammary Gland Cancer

The breast cancer is one of main localizations among malignant tumors in women of the Siberian Federal District. In the structure of morbidity it holds first place with such percentage as 20.4% and index of morbidity makes up to 51.2 per 100 000 of female population. The territories with increased and decreased risk are established. The features of prevalence of disease in a certain degree are conditioned by differences in demographic characteristics of populations. The indices of life-span, birth-rate in fertile age and divorce rate effect the level of morbidity of breast cancer in population.

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Breast sarcomas: Is now the time to change our mind?

Journal of Clinical Oncology ◽

10.1200/jco.2009.27.15_suppl.e21524 ◽

2009 ◽

Vol 27 (15_suppl) ◽

pp. e21524-e21524

Author(s):

I. Galaychuk

Keyword(s):

Breast Cancer ◽

Malignant Disease ◽

Malignant Tumors ◽

Breast Cancer Incidence ◽

Morphological Type ◽

Female Population ◽

Breast Sarcoma ◽

Malignant Breast ◽

Statistical Finding ◽

Breast Malignancies

e21524 Background: Primary breast sarcoma usually was considered a rare malignant disease [Adem et al., 2004]. The aim of this study is to show the incidence of breast sarcoma in the region with female population of about 600,000. Methods: Retrospective comparative analysis of breast sarcoma and breast cancer incidence in female of Ternopil region for 2000 - 2008. Descriptive statistical method was used. Results: The total of 101 cases of breast sarcoma was diagnosed in female of 39 - 76 years of age. Every year about 11 (6–18) primary breast sarcomas and 256 (233–279) patients with primary breast cancer were detected. The incidence rate of breast sarcoma was 1.14 per 100,000 women in 2000, 2.94 (in 2001), 1.48 (2002), 0.99 (2003), 2.16 (2004), 1.67 (2005), 2.53 (2006), 2.03 (2007) and 1.87/100,000 in 2008. The incidence of breast cancer was ranged from 37.3 to 46.4 per 100,000 of female population. Breast sarcoma consisted of 2.5% of the breast malignancies in 2000, 6.5% (in 2001), 3.3% (2002), 2.6% (2003), 5.4% (2004), 4.1% (2005), 5.9% (2006), 4.4% (2007) and 4.7% in 2008. Pathohistologic examination revealed angiosarcoma in 92.1% of cases. Thus, our findings are significantly different than data of other authors: f.e., the incidence of primary breast sarcoma is at 45 new cases per 10 million women [Confavreux et al., 2003], or 17 new cases per million women [Moore and Kinne, 1996], and breast sarcoma accounting for 0.0006% of breast malignancies which were diagnosed in 1910–2000 [Adem, 2004]. Taking into account all historical and recent data we can suggest beginning of biological changing in correlation between breast malignant tumors–carcinoma and sarcoma. Conclusions: Our statistical finding shows that incidence of breast sarcoma is 1.87 (0.99–2.94) per of 100,000 female population, and now sarcomas consist of 4.4% (2.5–6.5%) of all malignant breast tumors. Angiosarcoma is a most common (92.1%) morphological type of breast sarcomas. No significant financial relationships to disclose.

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Prognostic analysis of epidemiological indicators of the breast cancer among women in the Udmurt Republic

Kazan medical journal ◽

10.17816/kmj2019-975 ◽

2019 ◽

Vol 100 (6) ◽

Author(s):

S V Batov ◽

V M Napol'skikh ◽

N A Svirin ◽

I V Tchurakov ◽

I I Batova ◽

...

Keyword(s):

Breast Cancer ◽

Russian Federation ◽

Malignant Tumors ◽

Breast Cancer Incidence ◽

Female Population ◽

Prognostic Analysis ◽

Udmurt Republic ◽

The Russian Federation ◽

The Republic ◽

The Moment

Aim. To study a number of epidemiological indicators of a breast cancer in the Udmurt Republic for their assessment and prediction of dynamics. Methods. A retrospective analysis of data on a breast cancer of the population cancer register of the Udmurt Republic was performed in comparison with the corresponding statistics in the Russian Federation in 2017. For assessment of the received results the software BIOSTAT 4.3 was used. The forecast of epidemiological intensive indicators was calculated by methods of linear and polynomial trends. Results. The ratio of breast cancer (17.8% in 2017) among the female population of the Republic was the highest among all malignant tumors. In 2017 the crude indicator of breast cancer morbidity equaled 69.80 per 100 000, and standardized one 40.50 per 100 000. The standardized indicator of breast cancer incidence in Udmurtia was one of the lowest in Russia (77th rank place among 85 territorial entities). Crude mortality rate was 19.10 per 100 000, and standardized one 10.00 per 100 000 (82nd rank place in the Russian Federation). The ratio of the patients actively revealed (among registered numbre) was 45.8% (the average Russian value, 38.7%). Early diagnostics of tumor was carried out in 71.6% of patients, stage 1 of the disease was revealed in 34.3% of cases (in the Russian Federation average data, 69.9% and 26.0%, respectively). Forecasting till 2022 shows a trend of further growth of detectability of malignant tumors of breast at early stages among female population in the Udmurt Republic. Lethality of patients during the first year from the moment of diagnosis was 5.4% (the average Russian indicator, 6.0%). Conclusion. Morbidity and mortality rates of breast cancer in the Udmurt Republic in 2017 were lower than the average Russian indicators, and the statistical analysis does not show a negative trend till 2022.

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Analysis of the Incidence of the Female Population Omsk Region with Breast Cancer for Ten Years of (2003 - 2012)

Epidemiology and Vaccinal Prevention ◽

10.31631/2073-3046-2016-15-1-34-38 ◽

2016 ◽

Vol 15 (1) ◽

pp. 34-38

Author(s):

N. G. Shirlina ◽

V. L. Stasenko ◽

V. A. Shirinsky

Keyword(s):

Breast Cancer ◽

Rural Areas ◽

Malignant Tumors ◽

Breast Cancer Incidence ◽

Incidence Rates ◽

Female Population ◽

Regional Center ◽

Urban And Rural Residents ◽

Epidemiological Characteristics ◽

Cancer Incidence Rates

The paper presents the epidemiological characteristics of diseases of the female population of the Omsk region of breast cancer (BC) from 2003 to 2012, Determined the dynamics of morbidity. A comparative analysis of breast cancer incidence rates in urban and rural residents of the area. In the structure of malignant tumors of the female population of the Omsk region the proportion of breast cancer was 23.3% and was lower than the national average (20.0%). In rural areas, compared with the regional center had higher growth rates of incidence of breast cancer (1.5-fold).

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CLINICAL CHARACTERISTICS OF HER2-POSITIVE BREAST CANCER

Problems in oncology ◽

10.37469/0507-3758-2017-63-4-657-659 ◽

2017 ◽

Vol 63 (4) ◽

pp. 657-659

Author(s):

Gulya Miryusupova ◽

G. Khakimov ◽

N. Shayusupov

Keyword(s):

Breast Cancer ◽

Malignant Tumors ◽

Locally Advanced ◽

Immunohistochemical Analysis ◽

Average Level ◽

Her2 Positive ◽

Female Population ◽

Luminal B ◽

The Republic ◽

Positive Breast Cancer

Breast cancer ranks the first place in the structure of morbidity and mortality from malignant tumors of the female population of the Republic of Uzbekistan. According to data of 598 patients with breast cancer biological features of HER2/ neu-positive breast cancer were studied in 109 (18.2 %) cases/ In addition in 31 cases the immunohistochemical analysis on HER2/neu was established as “+2”, the FISH-test was not conducted. Among patients with HER2/neu-overexpressing breast cancer the patients of the indigenous ethnos (Uzbeks) were 54 %. In general among patients with HER2/neu-positive breast cancer the prevalence of locally advanced forms of the disease was noted. Luminal B with HER2/neu-overexpression (45 %) - the average age of patients was 50.4 ± 13.2 years, the average level of Ki67 was 37.8 % ; HER2/neu-overexpress-ing breast cancer (55 %) - the average age of patients was 51.3 ± 9.2 years, the average level of Ki67 was 47.1 %.

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BREAST CANCER METASTASIS IN THE STOMACH: WHEN THE GASTRECTOMY IS INDICATED ?

ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) ◽

10.1590/0102-6720201600020005 ◽

2016 ◽

Vol 29 (2) ◽

pp. 86-89 ◽

Cited By ~ 1

Author(s):

Marcus Vinicius Rozo RODRIGUES ◽

Valdir TERCIOTI-JUNIOR ◽

Luiz Roberto LOPES ◽

João de Souza COELHO-NETO ◽

Nelson Adami ANDREOLLO

Keyword(s):

Breast Cancer ◽

Primary Tumor ◽

Primary Breast Cancer ◽

Cancer Metastasis ◽

Statistical Significance ◽

Case Series ◽

Malignant Neoplasm ◽

Breast Cancer Metastasis ◽

Gastric Metastasis ◽

Female Population

ABSTRACT Background: Breast cancer is the most common malignant neoplasm in the female population. However, stomach is a rare site for metastasis, and can show up many years after initial diagnosis and treatment of the primary tumor. Aim: Analyze a case series of this tumor and propose measures that can diagnose it with more precocity. Methods: Were analyzed 12 patients with secondary gastric tumors. Immunohistochemistry has demonstrated that primary tumor was breast cancer. We retrieved information of age, histological type, interval between diagnosis of the primary breast cancer and its metastases, immunohistochemistry results, treatment and survival. Results: The mean age was 71.3 years (ranging 40-86). Ten cases had already been underwent mastectomy in the moment of the diagnosis of gastric metastasis. Two patients had diagnosis of both primary and secondary tumors concomitantly. At average, diagnosis of gastric metastasis was seven years after diagnosis of primary breast cancer (ranging 0-13). Besides, nine cases had also metastases in other organs, being bones the most affected ones. Immunohistochemistry of the metastases has shown positivity for CK7 antibody in 83.34%, estrogen receptor in 91.67%, progesterone receptor in 66.67% and AE1AE3 antibody in 75%, considering all 12 cases. Moreover, CK20 was absent significantly (66.67%). The positivity of BRST2 marker did not present statistical significance (41.67%). Eight cases were treated with chemotherapy associated or not with hormonal blockade. Surgical treatment of gastric metastasis was performed in four cases: three of them with total gastrectomy and one with distal gastrectomy. Follow-up has shown a mean survival of 14.58 months after diagnosis of metastasis, with only two patients still alive. Conclusion: Patients with a history of breast cancer presenting endoscopic diagnosis of gastric cancer it is necessary to consider the possibility of gastric metastasis of breast cancer. The confirmation is by immunohistochemistry and gastrectomy should be oriented in the absence of other secondary involvement and control of the primary lesion.

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