P277 Evaluation of body composition measures in cystic fibrosis: moving beyond body mass index for assessing nutritional status

2020 ◽  
Vol 19 ◽  
pp. S134
Author(s):  
D. Sills ◽  
M. Mitchell-Whyte ◽  
J. Dewar ◽  
H. Barr
Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 292
Author(s):  
Romana Suša ◽  
Vojislav Ćupurdija ◽  
Ljiljana Novković ◽  
Miloš Ratinac ◽  
Slobodan Janković ◽  
...  

Background and Objectives: This paper aims to show whether obstructive sleep apnea (OSA) severity increases the level of systemic inflammation markers regardless of body mass index (BMI) and body composition. Materials and Methods: In total, 128 patients with OSA were included in the study. Examinees were divided into two groups: one with mild OSA (apnea–hypopnea index (AHI) < 15) and one with moderate and severe OSA (AHI ≥ 15). Nutritional status was assessed using body mass index, body composition by dual X-ray absorptiometry. Systemic inflammation was assessed on the basis of plasma concentrations of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and serum level of C-reactive protein (CRP). Results: We found elevated mean values of the evaluated systemic inflammation markers (CRP, TNF-α, IL-6) in a group with AHI ≥ 15, although there was no statistical significance. Our research found a significant positive correlation with BMI (r = 0.633, p < 0.001), as well as with body fat percentage (r = 0.450, p = 0.024) and serum CRP values. Significant correlation was found between the plasma IL-6 concentration and body fat percentage (FM%) (r = 0.579, p = 0.003) and lean body mass (r = −0.501, p = 0.013). Multivariate regression analysis did not show any independent predictor (parameters of OSA, nutritional status, body composition) of the systemic inflammation markers. Conclusions: Neither one tested parameter (nutritional status and body composition) of the severity of OSA was identified as an independent prognostic factor for the severity of systemic inflammation in patients with OSA.


2021 ◽  
Vol 1 (5) ◽  
pp. 57-69
Author(s):  
I. Sokolov ◽  
O. I. Simonova ◽  
E. A. Roslavtseva ◽  
V. P. Chernevich ◽  
A. V. Vinokurova ◽  
...  

The pulmonary function which determines the prognosis of the disease in patients with cystic fibrosis (CF) depends directly on their nutritional status. Normal body mass index (BMI) for a given age/sex of the patient is considered to correspond with normal nutritional status. However, it is known that in CF patients only lean body mass (musculoskeletal and visceral) correlates directly with lung function. Bioimpedansometry, as the he method for assessing body composition in children with cystic fibrosis is actual, informative and available in pediatric practice. Body composition indicators can be used in these patients not only for diagnostic and prognostic purposes, but also for monitoring the course of the disease in a particular patient and correction of nutrition.The estimation of body composition with bioimpedance method in children with CF, carried out in this study, shows that in children with normal and even low BMI, the percentage of lean body mass is low, which requires measures to increase muscle/bone mass, the strength of the respiratory muscles especially, both by correcting the protein component of the diet, and by increasing physical / sports activity, in addition to compulsory respiratory physiotherapy.


2021 ◽  
Vol 8 ◽  
pp. 237437352110082
Author(s):  
Ioanna Loukou ◽  
Maria Moustaki ◽  
Argyri Petrocheilou ◽  
Ioanna Zarkada ◽  
Konstantinos Douros

During the first wave of the coronavirus pandemic in 2020, Greece adopted strict lockdown measures. We aimed to investigate the effects of lockdown and the resultant changes in the standard of care, on the lung function and somatic growth of cystic fibrosis (CF) patients. We analyzed data on body mass index and lung function of 103 CF patients 5.0- to 23.0-years-old before and after the lockdown period. Body mass index did not change significantly, but there was a significant improvement in lung function after the end of the lockdown period.


2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Pushpa Lata Tigga ◽  
Jaydip Sen

Introduction. Undernutrition continues to be a major public health problem throughout the developing world, particularly in sub-Saharan Africa and Asia including India. Limited studies suggest associations between maternal body mass index (BMI) and child nutritional status. The present study aims to determine the relationship between maternal BMI and children nutritional status. Methods. The study was conducted among 246 mothers who had given birth to single children (n=246) and belonged to the Proto-Australoid population of North Bengal, India. The anthropometric measurements of height and weight were recorded following standard procedures. Overall body composition was evaluated using BMI. Result. The results showed that overall mean BMI among mothers was 20.63±2.53 kg/m2, while those among boys and girls were 15.19±1.62 kg/m2 and 14.86±1.37 kg/m2 (p<0.001), respectively. The BMI of mothers were significantly and highly correlated with HAZ (0.709) and BMIZ (0.748) (p<0.001) of children. These are indicative of a strong genetic component between maternal and child anthropometry. Conclusion. The results indicate significant associations between mothers’ and children’s nutritional status. Assessments of body composition and nutritional status using BMI, especially among mothers and their children, are recommended.


2015 ◽  
Vol 28 (4) ◽  
pp. 359-369 ◽  
Author(s):  
Carina de Sousa SANTOS ◽  
Thais STEEMBURGO

Objective To examine the association between nutritional status and dietary factors in children and adolescents with cystic fibrosis that are carriers of delta F508 mutation. Methods Cross-sectional study of cystic fibrosis children and adolescents. Nutritional status (body mass index percentile) and dietary intake (3-day diet records presented as a percentage of estimated energy requirement) were assessed. Results Thirty six patients (median of 8.6; interquartile range 6.8-12.5 years; 50% male). The Poisson regression analysis showed that the carriers for delta F508 mutation had 60% lower prevalence ratio of body mass index ≥25° (PR=0.4; 95%IC=0.2-0.8) and 90% lower prevalence ratio (PR=0.1; confidence interval 95%IC=0.02-0.3) of ≥150% of estimated energy requirement when compared with non-delta F508 mutation carriers. The model was adjusted for lung function, estimated energy requirement, and body mass index. Conclusion Carriers for delta F508 mutation showed lower body mass index percentile and lower daily caloric consumption when compared with patients without this mutation.


2020 ◽  
pp. 1-26
Author(s):  
Jéssica Cumpian Silva ◽  
Ana Elisa Madalena Rinaldi ◽  
Francisco de Assis Guedes Vasconcelos ◽  
Maria Alice Altenburg Assis ◽  
Camila Medeiros Mazzeti ◽  
...  

ABSTRACT Objective: Our study aimed to describe body phenotypes (BP) estimated by multivariate analysis and their association with body mass. Design: Body phenotypes were defined based on demographic variables, anthropometric data (body mass, height, skinfolds and circumferences), body composition (phase angle measured by bioelectrical impedance analysis), biochemical parameters (triglycerides, glucose, total cholesterol ratio/Low Density Lipoproteins (LDL), haemoglobin and sexual maturation (pubic hair and breasts or gonads). Analysis of variance (ANOVA) was performed to verify the differences between skin colour and the stages of pubertal development, body phenotypes, body composition, anthropometric, and biochemical variables. Setting: Cities of São Paulo-SP, Piracicaba-SP and Florianópolis-SC from Brazil and the United States. Participants: 9269 adolescents aged between 10 to 15 years old. Results: The composition of BP was similar in all surveys, which are: BP1 was composed by skinfolds, body mass and circumferences variables; BP2 by pubic hair, breast in girls or gonad in boys, height and age; BP3 by cholesterol, triglycerides and glucose; and BP4 by phase angle, haemoglobin and glucose (negative loading). There was a strong correlation (r = 0.9, p <0.001) between BP1 and body mass index. Conclusion: We highlighted independence observed between biochemical parameters, anthropometry, body composition and sexual maturation. BP may support the calculation of scores for diagnosis of obesity based on anthropometric variables and overcome ambiguity in the isolated use of body mass index.


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