scholarly journals The Impact of Mumps Orchitis on Male Fertility: A Narrative Review of the Literature

2020 ◽  
Vol 20 ◽  
pp. S7
Author(s):  
N. Compton ◽  
S. Croghan ◽  
A. Jain ◽  
L. Scanlon ◽  
C. Kelly ◽  
...  
2017 ◽  
Vol 76 (4) ◽  
pp. 328-350 ◽  
Author(s):  
Daniel Lowrie ◽  
Robin Ray ◽  
David Plummer ◽  
Matthew Yau

This narrative review explores the literature regarding the drama of dying from several academic perspectives. Three key themes were identified including “The impact of blurred boundaries on roles and transitions,” “The orchestration of death and dying through time,” and “Contemporary dying and new machinery of control.” This review reveals the manner in which tightly scripted dying roles serve the needs of the living to a greater extent than those of the dying, by ensuring the depiction of both dying and death as phenomena which have been brought under the control of the living, thereby countering death anxiety. An incongruence between the actual experience of dying and contemporary dying scripts is also highlighted. The authors argue that this incongruence is hidden from the broader societal audience through the maintenance of a dying role that demands serenity and acceptance, thus downplaying or even hiding the actual end-of-life experiences of the dying themselves.


2017 ◽  
Vol 1 (1) ◽  
pp. 158-167 ◽  
Author(s):  
Kristina Staley

Much has been written about the impact of involvement on research and the people involved, but much less is known about the impact on researchers. Based on previous experience of evaluating involvement, I was aware that researchers often report learning something new from involvement. Patients/the public bring 'new' knowledge to researchers, informed by their lived experience and use of services. I therefore carried out a narrative review of the literature to explore in depth what researchers learn from involvement. The findings confirmed that researchers often gain new knowledge and skills through involvement, which can change their priorities, values and attitudes. Therefore, researchers often directly experience the impact of involvement themselves. This learning then changes their practice. It leads them to change the design, delivery and dissemination of their research. Thus, many of the reported outcomes of involvement might be underpinned by what the researchers learnt through the process. Reframing impacts on research as impacts on researchers' learning has implications for practice and for motivating researchers to work with patients and the public. Further research and future evaluations of involvement might usefully explore the links between researchers' learning and outcomes.


Author(s):  
Renata Finelli ◽  
Filomena Mottola ◽  
Ashok Agarwal

Alcohol abuse disorder is a serious condition, implicating more than 15 million people aged 12 years and older in 2019 in the United States. Ethanol (or ethyl alcohol) is mainly oxidized in the liver, resulting in the synthesis of acetaldehyde and acetate, which are toxic and carcinogenic metabolites, as well as in the generation of a reductive cellular environment. Moreover, ethanol can interact with lipids, generating fatty acid ethyl esters and phosphatidylethanol, which interfere with physiological cellular pathways. This narrative review summarizes the impact of excessive alcohol consumption on male fertility by describing its metabolism and how ethanol consumption may induce cellular damage. Furthermore, the impact of alcohol consumption on hormonal regulation, semen quality, and genetic and epigenetic regulations is discussed based on evidence from animal and human studies, focusing on the consequences on the offspring. Finally, the limitations of the current evidence are discussed. Our review highlights the association between chronic alcohol consumption and poor semen quality, mainly due to the development of oxidative stress, as well as its genotoxic impact on hormonal regulation and DNA integrity, affecting the offspring’s health. New landscapes of investigation are proposed for the identification of molecular markers for alcohol-associated infertility, with a focus on advanced OMICS-based approaches applied to the analysis of semen samples.


2016 ◽  
Vol 6 (3) ◽  
pp. 157-172 ◽  
Author(s):  
Bernie Divall ◽  
Helen Spiby ◽  
Julie Roberts ◽  
Denis Walsh

OBJECTIVE: To describe and summarize the current body of evidence on the subject of birth plans to develop a research agenda.METHOD: A narrative review was undertaken to offer a comprehensive overview of themes emerging from previous research in this area.FINDINGS: Thirty-five papers from 33 studies were retrieved and grouped into three main themes: the impact of birth plans on obstetric outcomes, women’s experiences and opinions of completing and using birth plans, and health care professionals’ beliefs about and experiences of the use of birth plans. Key findings relate to beliefs about the benefits and challenges of birth plans, as described by women and health care professionals and the impact of birth plans on a range of obstetric outcomes.CONCLUSION: This review brings together a range of studies around birth plans and synthesizes key themes. Little homogeneity was seen in the studies identified, and a wide variety of care contexts and childbirth philosophies were represented. Findings suggest the need for further research into whether there are ideal circumstances and environments for the completion of birth plans antenatally and whether disparities between expectations described in women’s plans and experiences in labor and birth can be reduced.


Author(s):  
Aggeliki Bistaraki ◽  
Maria Zarokosta ◽  
Theodoros Mariolis Sapsakos ◽  
George Skarpas ◽  
Georgios Nousios ◽  
...  

Author(s):  
Vieri Grandi ◽  
Silvia Alberti Violetti ◽  
Roberta La Selva ◽  
Stefano Cicchelli ◽  
Chiara Delfino ◽  
...  

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