scholarly journals Effect of dietary alpine butter rich in conjugated linoleic acid on milk fat composition of lactating sows

2008 ◽  
Vol 100 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Alexandra Schmid ◽  
Marius Collomb ◽  
Giuseppe Bee ◽  
Ulrich Bütikofer ◽  
Daniel Wechsler ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Growth Performance ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Control Diet ◽  
Milk Fat Depression ◽  
Lactating Sows ◽  
Fat Composition ◽  
Cla Isomers ◽  
Dietary Treatments

Multiparous sows (n 17) were included in a controlled cross-over-study in order to investigate the influence of a natural source of conjugated linoleic acid (CLA) (alpine butter) on the milk fatty acid composition of lactating sows (as an animal model for lactating women) and on the growth performance of their progeny. The usual fat source of a standard lactation diet was replaced by either CLA-rich alpine butter or margarine (control diet). Compared with the margarine diet, feeding the alpine butter-supplemented diet increased (P < 0·001) the CLA concentration in the milk fat (742·3 (sd 272·0) v. 107·7 (sd 34·7) mg/100 g fat). Eleven of fourteen CLA isomers were higher (P ≤ 0·004) in milk fat after feeding the alpine butter-supplemented diet but the transfer was not proportional. The milk fat concentration of the sow milk and the level of SFA, MUFA and PUFA were not (P>0·05) affected. Growth performance of the progeny was similar for both dietary treatments. In summary, the findings show that adding alpine butter to the diet does not provoke a milk fat depression and does not alter the composition of total SFA, MUFA and PUFA in sow milk but increases its CLA concentration.

scholarly journals Conjugated linoleic acid enhanced the immune function in broiler chicks

2005 ◽  
Vol 94 (5) ◽  
pp. 746-752 ◽  
Author(s):  
Haijun Zhang ◽  
Yuming Guo ◽  
Jianmin Yuan
Keyword(s):  
Linoleic Acid ◽  
Growth Performance ◽  
Conjugated Linoleic Acid ◽  
Antibody Production ◽  
Peripheral Blood ◽  
Lysozyme Activity ◽  
Control Group ◽  
Prostaglandin E ◽  
Broiler Chicks ◽  
Dietary Treatments

This study was undertaken to investigate the growth performance and immune responses of broiler chicks fed diets supplemented with conjugated linoleic acid (CLA). Two hundred and forty day-old Arbor Acre male broiler chicks were randomly allotted into four dietary treatments with different inclusion levels of CLA (0, 2·5, 5·0 or 10·0g pure CLA/kg) for 6 weeks. Growth performance, lysozyme activity, peripheral blood mononuclear cell (PBMC) proliferation, prostaglandin E2 (PGE2) synthesis and antibody production were investigated. There were no significant differences in growth performance among treatments (P>0·05). Chicks fed 10·0g CLA/kg diet produced 40% and 49% more lysozyme activity in serum and spleen than the control group at 21d of age (P<0·05). Dietary CLA enhanced the PBMC proliferation in response to concanavalin A at the age of 21 and 42d (P<0·05). Systemic and peripheral blood lymphocytic synthesis of PGE2 in chicks fed 10·0g CLA/kg diet was significantly decreased by 57% and 42% compared to chicks fed control diet (P<0·05). Antibody production to sheep red blood cell and bovine serum albumin were elevated in either 2·5 or 10·0g CLA/kg dietary treatments (P<0·05). The results indicated dietary CLA could enhance the immune response in broiler chicks, but did not alter the growth performance.

scholarly journals Kinetics of trans-10, cis-12-conjugated linoleic acid transfer to plasma and milk following an abomasal bolus in lactating dairy cows

2018 ◽  
Vol 120 (3) ◽  
pp. 259-268 ◽  
Author(s):  
Natalie L. Urrutia ◽  
Monica Toledo ◽  
Michel Baldin ◽  
Jennifer L. Ford ◽  
Michael H. Green ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Milk Fat Depression ◽  
Bolus Infusion ◽  
Bioactive Fatty Acids ◽  
Post Infusion ◽  
Kinetics Of ◽  
Transfer To Milk

AbstractTrans-10, cis-12-conjugated linoleic acid (CLA) is a potent bioactive fatty acids (FA) that causes milk fat depression in lactating animals. FA are transferred to milk directly through chylomicrons and indirectly by recycling through other tissues. The objective of this study was to characterise the kinetics of trans-10, cis-12 CLA transfer to plasma and milk after a single bolus infusion. Five multiparous mid-lactation cows received a single abomasal bolus infusion of an enriched CLA mixture providing 15 g of trans-10, cis-12 CLA and 15 g of cis-9, trans-11 CLA over a 30-min period. Plasma concentration of trans-10, cis-12 and cis-9, trans-11 CLA peaked 2 h post-bolus, reaching 0·29 and 0·38 % of total plasma FA, respectively, and returned to pre-bolus values at 72 h post-infusion. Milk trans-10, cis-12 CLA yield and concentration peaked 14 h post-bolus (0·25 g/h) and was not detectable in milk after 86 h. Total apparent transfer of trans-10, cis-12 CLA to milk was 41 %, with 73 % transferred to milk through the direct pool (chylomicrons) and the remaining 27 % transferred through the indirect pool (tissue recycling). Compartmental modelling revealed the existence of a transient unavailable pool of trans-10, cis-12 CLA in extravascular tissues represented primarily by the mammary gland, which slowly exchanges with an available pool for secretion in milk fat and transfer to milk. In conclusion, trans-10, cis-12 CLA is predominantly transferred to milk through the direct pathway; however, how this CLA isomer is processed within the mammary gland requires further investigation.

scholarly journals Milk fat responses to butterfat infusion during conjugated linoleic acid-induced milk fat depression in lactating dairy cows

2013 ◽  
Vol 96 (4) ◽  
pp. 2387-2399 ◽  
Author(s):  
D. Vyas ◽  
U. Moallem ◽  
B.B. Teter ◽  
A.R.K. Fardin-Kia ◽  
R.A. Erdman
Keyword(s):  
Linoleic Acid ◽  
Dairy Cows ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Milk Fat Depression ◽  
Lactating Dairy Cows

scholarly journals Conjugated linoleic acid-induced milk fat depression in lactating ewes is accompanied by reduced expression of mammary genes involved in lipid synthesis

2013 ◽  
Vol 96 (6) ◽  
pp. 3825-3834 ◽  
Author(s):  
M. Hussein ◽  
K.H. Harvatine ◽  
W.M.P.B. Weerasinghe ◽  
L.A. Sinclair ◽  
D.E. Bauman
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Lipid Synthesis ◽  
Milk Fat Depression

The effect of Ala293Val single nucleotide polymorphism in the stearoyl-CoA desaturase gene on conjugated linoleic acid concentration in milk fat of dairy cows

2010 ◽  
Vol 90 (4) ◽  
pp. 575-584 ◽  
Author(s):  
L.A. Clark ◽  
J.M. Thomson ◽  
S.S. Moore ◽  
M. Oba
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Linoleic Acid ◽  
Dairy Cows ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Control Diet ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Desaturation Index ◽  
Stearoyl Coa Desaturase

The objectives of this study were to determine the effects of the Ala293Val single nucleotide polymorphism in stearoyl-CoA desaturase (SCD) on the concentration of cis-9, trans-11 conjugated linoleic acid (CLA) in milk fat of dairy cows, and to identify a phenotypic indicator of cows with a greater genetic capability to produce CLA that is not affected by dietary lipid content. In Study 1, 12 cows, four of each Ala293Val SCD genotype, were fed either a control or an oil-supplemented diet in a cross-over design to examine effects of diet, genotype and their interaction. The CLA concentration in milk fat was greater for cows fed the oil-supplemented (4.4%) vs. the control diet (0.6%), but was not affected by the Ala293Val SCD genotype. In Study 2, the Ala293Val SCD genotype of 215 dairy cows at a commercial dairy did not affect milk yield, composition, or CLA concentration in milk fat. However, in both studies, C14:1 desaturation index was greater for the AA genotype compared with the others. The Ala293Val SCD genotype may not affect CLA production although the SCD Ala293 allele is associated with a higher C14:1 desaturation index possibly because effects of the SCD genotype vary depending on fatty acid chain length or origin.

The effect of dietary linola oil on CLA and other fatty acids in bovine milk

2008 ◽  
Vol 88 (2) ◽  
pp. 321-324
Author(s):  
L. Doepel ◽  
G. P. Toronchuk ◽  
J. R. E. Crowe
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Milk Fat ◽  
Dry Matter ◽  
Bovine Milk ◽  
Pork Lard ◽  
Milk Component ◽  
Fat Composition ◽  
Pork Fat ◽  
Dietary Treatments

To evaluate the effects of fat source on milk fat composition and milk conjugated linoleic acid (CLA) concentration, cows were fed diets that were high in either C18:2 or C18:0. Twenty-two Holstein cows were blocked by parity and milk production and randomly assigned within block to one of two dietary treatments containing either 3% pork fat (LARD) or 3% linola oil (OIL) on a dry matter (DM) basis. The diets were fed for 21 d. Feed intake and milk and milk component yields were unaffected by treatment, whereas milk fat percent was decreased with the linola oil treatment. The cis-9, trans-11 CLA concentration of milk from cows fed linola oil was significantly higher than from cows fed pork lard. Key words: CLA, fatty acids, linola oil, milk

Conjugated linoleic acid (CLA) effects on pups growth, milk composition and lipogenic enzymes in lactating rats

2007 ◽  
Vol 74 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Amanda Aparecida Hayashi ◽  
Sérgio Raposo de Medeiros ◽  
Marina Hojaij Carvalho ◽  
Dante Pazzanese Duarte Lanna
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Milk Fat ◽  
Fatty Acid Synthase ◽  
De Novo ◽  
Post Partum ◽  
Control Diet ◽  
Lipid Synthesis ◽  
Biological Properties

Conjugated linoleic acid (CLA) has a range of biological properties, including effects on lipid metabolism, milk and body composition in animals. This study investigated the effects of dietary CLA on lactating rats and development of the suckling pups. Dams were fed either a control diet or the same diet supplemented with 25 g/kg of a fat supplement containing 540 g CLA/kg (final concentration of 13·5 g CLA/kg diet) from parturition to the 15th day post-partum. The CLA mixture used in this study contained the following isomers (per 100 g): cis-9, trans-11 (24 g); cis-10, trans-12 (35 g); cis-8, trans-10 (15 g); cis-11, trans-13 (17 g) and others (9 g). On d 15 post partum, CLA supplementation reduced milk fat content by 33% and pup growth by 21%. The milk fatty acid profile, with decreased content of short and medium chain acids, suggests CLA inhibition was more pronounced for de novo lipid synthesis. Consistent with these results, activities of fatty acid synthase, glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase were reduced by CLA treatment in the mammary gland and liver. In contrast, the activity of NADP-malate dehydrogenase was unchanged.

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