Sex differences in fitness and selection for centric fusions between sex-chromosomes and autosomes
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SUMMARYA model of centric fusions between the X or Y chromosome and an autosome carrying a selected locus is studied. It is assumed that fusions are not associated with any fitness effects, and that all chromosomes disjoin regularly from their homologues. It is shown that a necessary condition for the fusion to be favoured is that there is a selectively maintained sex difference in allele frequencies at the selected locus. If this condition is satisfied, the initial rate of increase of a rare Y-autosome fusion is about three times that of an X-autosome fusion, with the same parameter values. Computer calculations of the final equilibrium states reached by populations containing such fusions were done.
2017 ◽
2003 ◽
Vol 19
(2)
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pp. 117-123
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2020 ◽
Vol 17
(6)
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pp. 1902
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2014 ◽
Vol 2014
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pp. 1-9
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