Sino-nasal assessment questionnaire: a specific outcome measure for rhinosinusitis, but what is the range in the asymptomatic population?

2006 ◽  
Vol 121 (7) ◽  
pp. 650-652
Author(s):  
F Younis ◽  
S Duvvi ◽  
T Walker ◽  
B Nirmal Kumar
Keyword(s):  
Outcome Measure ◽  
Healthy Adult ◽  
Normal Population ◽  
Adult Population ◽  
Sinus Surgery ◽  
Asymptomatic Group ◽  
Symptom Scores ◽  
Specific Outcome ◽  
The Difference ◽  
Assessment Questionnaire

The sino-nasal assessment questionnaire is a system used for scoring the symptoms of chronic rhinosinusitis. However, the range of scores for this questionnaire in the healthy adult population is unknown. We aimed to establish this by recruiting 100 healthy volunteers and comparing their sino-nasal assessment questionnaire scores with those of 100 individuals who had undergone sinus surgery for rhinosinusitis. The difference in mean scores in the symptomatic group (44.62) and the asymptomatic group (8.46) was statistically significant. However, there was substantial overlap between the scores of the two groups. Factors such as age, gender and smoking did not have a statistically significant impact on the eventual score in the asymptomatic group. We believe that symptom scores can only be used effectively when the range in the asymptomatic population is known. This is so that disease severity can be gauged in the context of the normal population and post-operative improvements can be forecast.

scholarly journals The range of the Oxford Shoulder Score in the asymptomatic population: a marker for post-operative improvement

2011 ◽  
Vol 93 (8) ◽  
pp. 629-633 ◽  
Author(s):  
F Younis ◽  
J Sultan ◽  
S Dix ◽  
PJ Hughes
Keyword(s):  
Normal Population ◽  
Adult Population ◽  
Asymptomatic Group ◽  
Oxford Shoulder Score ◽  
Asymptomatic Volunteers ◽  
Symptom Scores ◽  
Asymptomatic Adult ◽  
The Difference ◽  
Asymptomatic Individuals ◽  
Shoulder Score

INTRODUCTION The Oxford Shoulder Score (OSS) is a validated scoring system used to assess the degree of pain and disability caused by shoulder pathology. To date there is no knowledge of the range of the OSS in the healthy adult population. This study aimed to establish the range in asymptomatic individuals. METHODS The OSS of 100 asymptomatic volunteers was compared with the pre-operative OSS of 100 symptomatic individuals who had had elective shoulder surgery performed at the Royal Preston Hospital. RESULTS The difference in mean scores in the operated group (36.7) and the asymptomatic group (15.3) was statistically significant (p<0.0001). There was, however, a substantial overlap between the scores of the two groups (operated group range: 19–55, asymptomatic group range: 12–47). Factors such as age, sex, body mass index, co-morbidities and smoking did not have a statistically significant impact on the eventual score in the asymptomatic group. CONCLUSIONS This study has established the range of OSS in the asymptomatic adult population. Symptom scores can only be used effectively when the range in the asymptomatic population is known. This is so that disease severity can be gauged in the context of the normal population and post-operative improvements can be forecast more accurately.

scholarly journals The Prevalence and Effect of Asthma on Adults with Chronic Rhinosinusitis

2007 ◽  
Vol 86 (7) ◽  
pp. 409-411 ◽  
Author(s):  
Melanie W. Seybt ◽  
Kevin C. McMains ◽  
Stilianos E. Kountakis
Keyword(s):  
Chronic Rhinosinusitis ◽  
Nasal Congestion ◽  
Adult Population ◽  
Tertiary Care ◽  
Sinus Surgery ◽  
Postnasal Drip ◽  
Asthma Patients ◽  
General Adult Population ◽  
Tertiary Care Institution ◽  
The Difference

We conducted a retrospective review of 145 consecutively presenting adults treated for chronic rhinosinusitis (CRS) in a tertiary care institution. Our goals were to determine (1) the prevalence of asthma in these patients, (2) the prevalence of specific CRS symptoms in both asthmatic and nonasthmatic patients, and (3) the frequency of surgical treatment for CRS in patients with and without asthma. We found that asthma was present in 23.4% of CRS patients, a much higher rate than the 5% prevalence of asthma in the general adult population. Patients with asthma had a significantly higher prevalence of nasal polyps (47 vs. 22%; p = 0.004), olfactory dysfunction (26 vs. 6%; p = 0.001), and nasal congestion (85 vs. 60%; p = 0.027) than did those without asthma. Patients without asthma had a significantly higher prevalence of headache (72 vs. 53%; p = 0.037) and rhinorrhea (58 vs. 38%; p = 0.047). The prevalence of postnasal drip and environmental allergies in the two groups was similar. Although the difference between the proportions of patients with and without asthma who required primary sinus surgery was not statistically significant (76 vs. 64%; p = 0.175), patients with asthma did require significantly more revision sinus procedures overall (mean: 2.9 vs. 1.5; p = 0.003).

The 6-min walk test: responses in healthy Canadians aged 45 to 85 years

2011 ◽  
Vol 36 (5) ◽  
pp. 643-649 ◽  
Author(s):  
Kylie Hill ◽  
Lisa M. Wickerson ◽  
Lynda J. Woon ◽  
Afshin Heidar Abady ◽  
Tom J. Overend ◽  
...  
Keyword(s):  
Outcome Measure ◽  
Healthy Adult ◽  
Adult Population ◽  
Gas Analysis ◽  
Walk Test ◽  
Walk Distance ◽  
Main Outcome Measure ◽  
The Third ◽  
Cardiorespiratory Responses ◽  
Analysis System

We sought to describe responses to the 6-min walk test (6MWT) in healthy Canadian adults in order to facilitate interpretation of its results in patient populations. Seventy-seven healthy Canadians aged 45 to 85 years (65 ± 11 years, 40 females) completed this study. During a single visit, three 6MWTs were undertaken. The main outcome measure was 6-min walk distance (6MWD). Age, gender, height, and weight were recorded. In 61 (79%) participants, cardiorespiratory variables were collected during the third 6MWT using a calibrated portable gas analysis system. The 6MWD increased between the first and second test (615 ± 96 to 639 ± 98 m; p < 0.001) with no further improvement on the third test (638 ± 99 m; p = 0.945). The best 6MWD from the first 2 tests was 640 ± 99 m (range 416 to 880 m). A greater 6MWD was achieved by males compared with females (672 ± 94 vs. 611 ± 93 m; p = 0.005). The following equation accounted for 49% of the variance in 6MWD: 6MWD = 970.7 + (–5.5 × age) + (56.3 × gender), where females = 0, males = 1. The 6MWT elicited large cardiorespiratory responses with minimal symptoms. The rate of oxygen uptake measured at test-end was associated with the 6MWD (r = 0.802; p < 0.001). These data allow the 6MWD achieved in Canadian adults to be expressed as a percentage of the predicted value and provide researchers and clinicians with values for the expected cardiorespiratory responses in a healthy adult population for the purpose of comparison with patient populations.

Discrepancies between echocardiographic measurements of left ventricular mass in a healthy adult population

1999 ◽  
Vol 97 (3) ◽  
pp. 377-383 ◽  
Author(s):  
Jenny A. DEAGUE ◽  
Catherine M. WILSON ◽  
Leeanne E. GRIGG ◽  
Stephen B. HARRAP
Keyword(s):  
Healthy Adult ◽  
Adult Population ◽  
Statistical Test ◽  
Left Ventricular ◽  
Altman Analysis ◽  
Cardiovascular Morbidity And Mortality ◽  
Lv Mass ◽  
Heart Size ◽  
The Difference ◽  
American Society

Increased left ventricular (LV) mass is associated with increased cardiovascular morbidity and mortality. LV mass is commonly estimated from echocardiography according to the Penn or ASE (American Society of Echocardiography) conventions. No formal statistical test of agreement between these methods has been published. Therefore we compared M-mode echocardiographic LV mass estimates by the Penn and ASE methods in a normal adult population. M-mode echocardiographic tracings were obtained in 169 healthy volunteers and used to calculate LV mass using the Penn and ASE methods. Median values of the estimates were similar [Penn, 126 g (interquartile range 96–170 g); ASE, 129 g (105–164 g); P = 0.08] and were highly intercorrelated (r = 0.98, P < 0.0001). However, the Bland–Altman analysis of agreement revealed significant inconsistencies between Penn and ASE LV mass values. The difference between Penn and ASE values was correlated significantly with heart size (P < 0.0001), such that, for small hearts, the Penn LV mass was lower than the ASE LV mass; in contrast, for large hearts, Penn estimates were greater than ASE values. In the upper 5% of the LV mass distribution, the median value for the Penn LV mass index was 132.4 g/m2, compared with 116.5 g/m2 for ASE values (2P = 0.017). Thus the two most common methods of echocardiographic estimation of LV mass differ significantly at the upper and lower ends of the heart size distribution. These results have important implications for both cardiac research and clinical evaluation.

Sleep Habits and Sleep Patterns in Healthy Adult Population in Chennai

2012 ◽  
Vol 3 (5) ◽  
pp. 507-508
Author(s):  
Dr. M. Ganesh Dr. M. Ganesh ◽  
◽  
Dr.S.A.Sridevi Dr.S.A.Sridevi ◽  
Dr. T.Janagan Dr. T.Janagan
Keyword(s):  
Healthy Adult ◽  
Adult Population ◽  
Sleep Patterns ◽  
Sleep Habits

scholarly journals Validation of the German version of the Family Reported Outcome Measure (FROM-16) to assess the impact of disease on the partner or family member

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Susanne A. Elsner ◽  
Sam S. Salek ◽  
Andrew Y. Finlay ◽  
Anna Hagemeier ◽  
Catherine J. Bottomley ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Family Member ◽  
Internal Consistency ◽  
Outcome Measure ◽  
Test Validity ◽  
Family Members ◽  
German Version ◽  
The Family ◽  
The Difference ◽  
The Impact

Abstract Background The Family Reported Outcome Measure (FROM-16) assesses the impact of a patient’s chronic illness on the quality of life (QoL) of the patient’s partner or family members. The aim of the study was to translate, explore the structure of and validate the FROM-16. Methods The questionnaire was translated from English into German (forward, backward, four independent translators). Six interviews with family members were conducted to confirm the questionnaire for linguistic, conceptual, semantic and experiential equivalence and its practicability. The final German translation was tested for internal consistency, reproducibility and test validity. Criterion validity was tested by correlating the scores of the FROM-16 and the Global Health Scale (GHS). Principal component analysis, factor analysis, and confirmatory factor analysis was used to assess the questionnaire’s structure and its domains. Reliability and reproducibility were tested computing the intraclass correlation coefficient (ICC) using one sample t-test for testing the hypothesis that the difference between the scores was not different from zero. Results Overall, 83 family members (61% female, median age: 61 years) completed the questionnaire at two different times (mean interval: 22 days). Internal consistency was good for the FROM-16 scores (Cronbach’s α for total score = 0.86). In those with stable GHS, the ICC for the total score was 0.87 and the difference was not different from zero (p = 0.262) indicating reproducible results. A bi-factor model with a general factor including all items, and two sub-factors comprising the items from the original 2-factor construct had the best fit. Conclusions The German FROM-16 has good reliability, test validity and practicability. It can be considered as an appropriate and generic tool to measure QoL of a patient’s partner or family member. Due to the presence of several cross-loadings we do not recommend the reporting of the scores of the two domains proposed for the original version of FROM-16 when using the German version. Thus, in reporting the results emphasis should be put on the total score. Trial registration: Retrospectively registered: DRKS00021070.

Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population

2008 ◽  
Vol 19 (1) ◽  
pp. 46-50 ◽  
Author(s):  
M. Sundaram ◽  
J. Mohanakrishnan ◽  
K.G. Murugavel ◽  
E.M. Shankar ◽  
S. Solomon ◽  
...  
Keyword(s):  
Healthy Adult ◽  
Adult Population ◽  
Reference Intervals ◽  
Ethnic Variation ◽  
South Indian
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