Beyond the limits of the brain as a physical system

2000 ◽  
Vol 23 (3) ◽  
pp. 405-406
Author(s):  
V. K. Jirsa ◽  
J. A. S. Kelso

Nunez's description of the brain as a medium capable of wave propagation has provided some fundamental insights into its dynamics. This approach soon reaches the descriptive limits of the brain as a physical system, however. We point out some biological constraints which differentiate the brain from physical systems and we elaborate on its consequences for future research.

2021 ◽  
Vol 11 (12) ◽  
pp. 5458
Author(s):  
Sangjun Kim ◽  
Kyung-Joon Park

A cyber-physical system (CPS) is the integration of a physical system into the real world and control applications in a computing system, interacting through a communications network. Network technology connecting physical systems and computing systems enables the simultaneous control of many physical systems and provides intelligent applications for them. However, enhancing connectivity leads to extended attack vectors in which attackers can trespass on the network and launch cyber-physical attacks, remotely disrupting the CPS. Therefore, extensive studies into cyber-physical security are being conducted in various domains, such as physical, network, and computing systems. Moreover, large-scale and complex CPSs make it difficult to analyze and detect cyber-physical attacks, and thus, machine learning (ML) techniques have recently been adopted for cyber-physical security. In this survey, we provide an extensive review of the threats and ML-based security designs for CPSs. First, we present a CPS structure that classifies the functions of the CPS into three layers: the physical system, the network, and software applications. Then, we discuss the taxonomy of cyber-physical attacks on each layer, and in particular, we analyze attacks based on the dynamics of the physical system. We review existing studies on detecting cyber-physical attacks with various ML techniques from the perspectives of the physical system, the network, and the computing system. Furthermore, we discuss future research directions for ML-based cyber-physical security research in the context of real-time constraints, resiliency, and dataset generation to learn about the possible attacks.


J ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 147-153
Author(s):  
Paula Morella ◽  
María Pilar Lambán ◽  
Jesús Antonio Royo ◽  
Juan Carlos Sánchez

Among the new trends in technology that have emerged through the Industry 4.0, Cyber Physical Systems (CPS) and Internet of Things (IoT) are crucial for the real-time data acquisition. This data acquisition, together with its transformation in valuable information, are indispensable for the development of real-time indicators. Moreover, real-time indicators provide companies with a competitive advantage over the competition since they enhance the calculus and speed up the decision-making and failure detection. Our research highlights the advantages of real-time data acquisition for supply chains, developing indicators that would be impossible to achieve with traditional systems, improving the accuracy of the existing ones and enhancing the real-time decision-making. Moreover, it brings out the importance of integrating technologies 4.0 in industry, in this case, CPS and IoT, and establishes the main points for a future research agenda of this topic.


2021 ◽  
Vol 22 (11) ◽  
pp. 6141
Author(s):  
Teodora Larisa Timis ◽  
Ioan Alexandru Florian ◽  
Sergiu Susman ◽  
Ioan Stefan Florian

Aneurysms and vascular malformations of the brain represent an important source of intracranial hemorrhage and subsequent mortality and morbidity. We are only beginning to discern the involvement of microglia, the resident immune cell of the central nervous system, in these pathologies and their outcomes. Recent evidence suggests that activated proinflammatory microglia are implicated in the expansion of brain injury following subarachnoid hemorrhage (SAH) in both the acute and chronic phases, being also a main actor in vasospasm, considerably the most severe complication of SAH. On the other hand, anti-inflammatory microglia may be involved in the resolution of cerebral injury and hemorrhage. These immune cells have also been observed in high numbers in brain arteriovenous malformations (bAVM) and cerebral cavernomas (CCM), although their roles in these lesions are currently incompletely ascertained. The following review aims to shed a light on the most significant findings related to microglia and their roles in intracranial aneurysms and vascular malformations, as well as possibly establish the course for future research.


2021 ◽  
Author(s):  
Hugh McGovern ◽  
Marte Otten

Bayesian processing has become a popular framework by which to understand cognitive processes. However, relatively little has been done to understand how Bayesian processing in the brain can be applied to understanding intergroup cognition. We assess how categorization and evaluation processes unfold based on priors about the ethnic outgroup being perceived. We then consider how the precision of prior knowledge about groups differentially influence perception depending on how the information about that group was learned affects the way in which it is recalled. Finally, we evaluate the mechanisms of how humans learn information about other ethnic groups and assess how the method of learning influences future intergroup perception. We suggest that a predictive processing framework for assessing prejudice could help accounting for seemingly disparate findings on intergroup bias from social neuroscience, social psychology, and evolutionary psychology. Such an integration has important implications for future research on prejudice at the interpersonal, intergroup, and societal levels.


2011 ◽  
Vol 21 (3) ◽  
pp. 88-95 ◽  
Author(s):  
Deryk S. Beal

We are amassing information about the role of the brain in speech production and the potential neural limitations that coincide with developmental stuttering at a fast rate. As such, it is difficult for many clinician-scientists who are interested in the neural correlates of stuttering to stay informed of the current state of the field. In this paper, I aim to inspire clinician-scientists to tackle hypothesis-driven research that is grounded in neurobiological theory. To this end, I will review the neuroanatomical structures, and their functions, which are implicated in speech production and then describe the relevant differences identified in these structures in people who stutter relative to their fluently speaking peers. I will conclude the paper with suggestions on directions of future research to facilitate the evolution of the field of neuroimaging of stuttering.


2019 ◽  
Author(s):  
Michael Elliott

The binding problem refers to the puzzle of how the brain combines objects’ properties such as motion, color, shape, location, sound, etc., from diverse regions of the brain and forms a unified subjective experience. Holographic physical systems, recently discovered darlings of theoretical physics, began with research into black holes but have since evolved into the study of condensed matter systems in the laboratory like superfluids and superconductors. A primary example is the AdS/CFT correspondence. A recent conjecture of this correspondence suggests that holographic systems combine information from across a boundary surface, sort out the simplest description of said information, and, in turn, use it to determine the geometry of spacetime itself in the interior - a kind of geometric hologram. Although we would never tend to think of these two processes as related, in this paper we point out ten similarities between the two and show that holographic systems are the only physical systems that match the subjective and computational characteristics of the binding problem.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Natalie S. Joe ◽  
Christine Hodgdon ◽  
Lianne Kraemer ◽  
Kristin J. Redmond ◽  
Vered Stearns ◽  
...  

AbstractBreast cancer is the most commonly diagnosed cancer in women worldwide. Approximately one-tenth of all patients with advanced breast cancer develop brain metastases resulting in an overall survival rate of fewer than 2 years. The challenges lie in developing new approaches to treat, monitor, and prevent breast cancer brain metastasis (BCBM). This review will provide an overview of BCBM from the integrated perspective of clinicians, researchers, and patient advocates. We will summarize the current management of BCBM, including diagnosis, treatment, and monitoring. We will highlight ongoing translational research for BCBM, including clinical trials and improved detection methods that can become the mainstay for BCBM treatment if they demonstrate efficacy. We will discuss preclinical BCBM research that focuses on the intrinsic properties of breast cancer cells and the influence of the brain microenvironment. Finally, we will spotlight emerging studies and future research needs to improve survival outcomes and preserve the quality of life for patients with BCBM.


2021 ◽  
Vol 82 (3) ◽  
pp. 12-17
Author(s):  
Bohdan Stadnyk ◽  
◽  
Vasyl Yatsuk ◽  
Mykola Mykyjchuk ◽  
Svyatoslav Yatsyshyn ◽  
...  

The analysis of the concept of Open-Science Space is carried out. The existence of ways to achieve reproducibility and traceability of research results performed by a group of worldwide situated Cyber-physical system operators/supervisors is shown. Ways to ensure the efficient operation of Cyber-physical systems as complex technological nondemountable objects with high requirements for metrological characteristics have been studied. To develop the scattered cyberphysical systems, the portable stable-in-time code-controlled measures of physical quantities have been studied. They have to be metrologically confirmed in the laboratory before the delivery to the site of the measuring subsystem for its calibration.


Cloud service provider in cloud environment will provide or provision resource based on demand from the user. The cloud service provider (CSP) will provide resources as and when required or demanded by the user for execution of the job on the cloud environment. The CSP will perform this in a static and dynamic manner. The CSP should also consider various other factors in order to provide the resources to the user, the prime among that will be the Service Level Agreement (SLA), which is normally signed by the user and cloud service provider during the inception phase of service. There are many algorithm which are used in order to allocate resources to the user in cloud environment. The algorithm which is proposed will be used to reduce the amount of energy utilized in performing various job execution in cloud environment. Here the energy utilized for execution of various jobs are taken into account by increasing the number of virtual machines that are used on a single physical host system. There is no thumb rule to calculate the number of virtual machines to be executed on a single host. The same can be derived by calculating the amount of space, speed required along with the time to execute the job on a virtual machine. Based up on this we can derive the number of Virtual machine on a single host system. There can be 10 virtual machines on a single system or even 20 number of virtual machines on single physical system. But if the same is calculated by the equation then the result will be exactly matching with the threshold capacity of the physical system[1]. If more number of physical systems are used to execute fewer virtual machines on each then the amount of energy consumed will be very high. So in order to reduce the energy consumption , the algorithm can be used will not only will help to calculate the number of virtual machines on single physical system , but also will help to reduce the energy as less number of physical systems will be in need[2].


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