Moving toward a neuroplasticity view of bilingualism, executive control, and aging

ABSTRACTNormal aging is an inevitable race between increasing knowledge and decreasing cognitive capacity. Crucial to understanding and promoting successful aging is determining which of these factors dominates for particular neurocognitive functions. Here, we focus on the human capacity for language, for which healthy older adults are simultaneously advantaged and disadvantaged. In recent years, a more hopeful view of cognitive aging has emerged from work suggesting that age-related declines in executive control functions are buffered by life-long bilingualism. In this paper, we selectively review what is currently known and unknown about bilingualism, executive control, and aging. Our ultimate goal is to advance the views that these issues should be reframed as a specific instance of neuroplasticity more generally and, in particular, that researchers should embrace the individual variability among bilinguals by adopting experimental and statistical approaches that respect the complexity of the questions addressed. In what follows, we set out the theoretical assumptions and empirical support of the bilingual advantages perspective, review what we know about language, cognitive control, and aging generally, and then highlight several of the relatively few studies that have investigated bilingual language processing in older adults, either on their own or in comparison with monolingual older adults. We conclude with several recommendations for how the field ought to proceed to achieve a more multifactorial view of bilingualism that emphasizes the notion of neuroplasticity over that of simple bilingual versus monolingual group comparisons.

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Strategies and cognitive reserve to preserve lexical production in aging

GeroScience ◽

10.1007/s11357-021-00367-5 ◽

2021 ◽

Author(s):

Monica Baciu ◽

Sonja Banjac ◽

Elise Roger ◽

Célise Haldin ◽

Marcela Perrone-Bertolotti ◽

...

Keyword(s):

Older Adults ◽

Cognitive Aging ◽

Individual Variability ◽

Future Research ◽

Aging Effects ◽

Main Hypothesis ◽

Compensatory Strategies ◽

Age Related ◽

Complementary Domain

AbstractIn the absence of any neuropsychiatric condition, older adults may show declining performance in several cognitive processes and among them, in retrieving and producing words, reflected in slower responses and even reduced accuracy compared to younger adults. To overcome this difficulty, healthy older adults implement compensatory strategies, which are the focus of this paper. We provide a review of mainstream findings on deficient mechanisms and possible neurocognitive strategies used by older adults to overcome the deleterious effects of age on lexical production. Moreover, we present findings on genetic and lifestyle factors that might either be protective or risk factors of cognitive impairment in advanced age. We propose that “aging-modulating factors” (AMF) can be modified, offering prevention opportunities against aging effects. Based on our review and this proposition, we introduce an integrative neurocognitive model of mechanisms and compensatory strategies for lexical production in older adults (entitled Lexical Access and Retrieval in Aging, LARA). The main hypothesis defended in LARA is that cognitive aging evolves heterogeneously and involves complementary domain-general and domain-specific mechanisms, with substantial inter-individual variability, reflected at behavioral, cognitive, and brain levels. Furthermore, we argue that the ability to compensate for the effect of cognitive aging depends on the amount of reserve specific to each individual which is, in turn, modulated by the AMF. Our conclusion is that a variety of mechanisms and compensatory strategies coexist in the same individual to oppose the effect of age. The role of reserve is pivotal for a successful coping with age-related changes and future research should continue to explore the modulating role of AMF.

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Successful Aging

10.2310/psych.13074 ◽

2017 ◽

Author(s):

Dilip Jeste ◽

Jeanne Maglione

Keyword(s):

Older Adults ◽

Cognitive Aging ◽

Successful Aging ◽

Healthy Aging ◽

Biological Aging ◽

Medical Illness ◽

Key Words Aging ◽

Age Related ◽

Different Populations ◽

Multiple Domains

The number of older adults in our society is increasing rapidly. Aging is complex and may occur at varying rates across multiple domains, including biological aging, cognitive aging, and emotional aging. Age-related medical conditions are now among the leading causes of morbidity and mortality among older adults, making healthy aging a major public health priority. Successful aging encompasses more than longevity, medical health, or freedom from disability. It can be viewed as a multidimensional construct including minimization of disability and medical illness combined with maximization of physical, cognitive, emotional, and social functioning. We review the current literature regarding successful aging. We also discuss strategies to improve the likelihood of successful aging and several key advances, such as definitions of successful aging in different populations, neuroplasticity of aging, wisdom as an empirical construct, the concept of a good (or successful) death, and the development of age-friendly communities. This review contains 3 figures, 5 tables, and 53 references. Key words: aging, elderly, older adult, successful aging, successful aging interventions

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Disturbance of attention network functions in Chinese healthy older adults: an intra-individual perspective

International Psychogeriatrics ◽

10.1017/s1041610215001556 ◽

2015 ◽

Vol 28 (2) ◽

pp. 291-301 ◽

Cited By ~ 9

Author(s):

Hanna Lu ◽

Ada W. T. Fung ◽

Sandra S. M. Chan ◽

Linda C. W. Lam

Keyword(s):

Older Adults ◽

Executive Control ◽

Age Groups ◽

Individual Variability ◽

Healthy Ageing ◽

Executive Attention ◽

Attention Network ◽

Chinese Older Adults ◽

Healthy Older Adults ◽

Age Related

ABSTRACTBackground:Intra-individual variability (IIV) and the change of attentional functions have been reported to be susceptible to both healthy ageing and pathological ageing. The current study aimed to evaluate the IIV of attention and the age-related effect on alerting, orienting, and executive control in cognitively healthy older adults.Method:We evaluated 145 Chinese older adults (age range of 65–80 years, mean age of 72.41 years) with a comprehensive neuropsychological battery and the Attention network test (ANT). A two-step strategy of analytical methods was used: Firstly, the IIV of older adults was evaluated by the intraindividual coefficient of variation of reaction time (ICV-RT). The correlation between ICV-RT and age was used to evaluate the necessity of subgrouping. Further, the comparisons of ANT performance among three age groups were performed with processing speed adjusted.Results:Person's correlation revealed significant positive correlations between age and IIV (r = 0.185, p = 0.032), age and executive control (r = 0.253, p = 0.003). Furthermore, one-way ANOVA comparisons among three age groups revealed a significant age-related disturbance on executive control (F = 4.55, p = 0.01), in which oldest group (group with age >75 years) showed less efficient executive control than young-old (group with age 65–70 years) (Conventional score, p = 0.012; Ratio score, p = 0.020).Conclusion:Advancing age has an effect on both IIV and executive attention in cognitively healthy older adults, suggesting that the disturbance of executive attention is a sensitive indicator to reflect healthy ageing. Its significance to predict further deterioration should be carefully evaluated with prospective studies.

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Activity Engagement in Cognitive Aging: A Review of the Evidence

Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders ◽

10.1044/nnsld23.1.35 ◽

2013 ◽

Vol 23 (1) ◽

pp. 1-12 ◽

Cited By ~ 2

Author(s):

Yvonne Rogalski ◽

Muriel Quintana

Keyword(s):

Older Adults ◽

Cognitive Decline ◽

Cognitive Aging ◽

Social Activity ◽

Current Evidence ◽

Omega 3 ◽

Neuroprotective Effects ◽

Activity Engagement ◽

Age Related ◽

Age Related Cognitive Decline

The population of older adults is rapidly increasing, as is the number and type of products and interventions proposed to prevent or reduce the risk of age-related cognitive decline. Advocacy and prevention are part of the American Speech-Language-Hearing Association’s (ASHA’s) scope of practice documents, and speech-language pathologists must have basic awareness of the evidence contributing to healthy cognitive aging. In this article, we provide a brief overview outlining the evidence on activity engagement and its effects on cognition in older adults. We explore the current evidence around the activities of eating and drinking with a discussion on the potential benefits of omega-3 fatty acids, polyphenols, alcohol, and coffee. We investigate the evidence on the hypothesized neuroprotective effects of social activity, the evidence on computerized cognitive training, and the emerging behavioral and neuroimaging evidence on physical activity. We conclude that actively aging using a combination of several strategies may be our best line of defense against cognitive decline.

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Internet Navigation Skills for Financial Management: Associations with Age, Neurocognitive Performance, and Functional Capacity

10.31234/osf.io/q46r8 ◽

2020 ◽

Author(s):

Samina Rahman ◽

Victoria Kordovski ◽

Savanna Tierney ◽

Steven Paul Woods

Keyword(s):

Older Adults ◽

Functional Capacity ◽

Financial Management ◽

Internet Banking ◽

Online Banking ◽

Neurocognitive Performance ◽

Younger Adults ◽

Neurocognitive Functions ◽

Age Related ◽

Use Factors

Objective: Online banking is becoming increasingly common among older adults, whomay experience difficulties effectively navigating this instrumental technology. Thisstudy examined age effects on a performance-based Internet banking task and itsassociation with neurocognitive ability and functional capacity in older and youngeradults. Method: Thirty-five older adults and 50 younger adults completed anexperimenter-controlled online banking measure in which they independentlyperformed a series of naturalistic financial tasks (e.g., account transfers, bill paying).Participants also completed a standardized battery of neuropsychological tests andmeasures of functional capacity. Results: Older adults were markedly slower and lessaccurate in completing the Internet-based banking task, which was not confounded byother demographic, mood, or computer use factors. Higher scores on measures ofneurocognition and financial functional capacity were both strongly associated withhigher Internet-based banking task accuracy scores and quicker completion times inthe older, but not the younger adults. Conclusions: Findings suggest that older adultsexperience difficultly quickly and accurately navigating online banking platforms, whichmay be partly related to age-related declines in neurocognitive functions and basicfinancial capacity. Future studies might examine whether neurocognitive approaches toremediation and compensation can be used to improve online banking capacity inolder adults.

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Resting‐State EEG Microstates Parallel Age‐Related Differences in Allocentric Spatial Working Memory Performance

Brain Topography ◽

10.1007/s10548-021-00835-3 ◽

2021 ◽

Author(s):

Adeline Jabès ◽

Giuliana Klencklen ◽

Paolo Ruggeri ◽

Christoph M. Michel ◽

Pamela Banta Lavenex ◽

...

Keyword(s):

Older Adults ◽

Working Memory ◽

Resting State ◽

Cognitive Aging ◽

Temporal Dynamics ◽

Spatial Working Memory ◽

Brain Activity ◽

Memory Performance ◽

Brain Regions ◽

Age Related

AbstractAlterations of resting-state EEG microstates have been associated with various neurological disorders and behavioral states. Interestingly, age-related differences in EEG microstate organization have also been reported, and it has been suggested that resting-state EEG activity may predict cognitive capacities in healthy individuals across the lifespan. In this exploratory study, we performed a microstate analysis of resting-state brain activity and tested allocentric spatial working memory performance in healthy adult individuals: twenty 25–30-year-olds and twenty-five 64–75-year-olds. We found a lower spatial working memory performance in older adults, as well as age-related differences in the five EEG microstate maps A, B, C, C′ and D, but especially in microstate maps C and C′. These two maps have been linked to neuronal activity in the frontal and parietal brain regions which are associated with working memory and attention, cognitive functions that have been shown to be sensitive to aging. Older adults exhibited lower global explained variance and occurrence of maps C and C′. Moreover, although there was a higher probability to transition from any map towards maps C, C′ and D in young and older adults, this probability was lower in older adults. Finally, although age-related differences in resting-state EEG microstates paralleled differences in allocentric spatial working memory performance, we found no evidence that any individual or combination of resting-state EEG microstate parameter(s) could reliably predict individual spatial working memory performance. Whether the temporal dynamics of EEG microstates may be used to assess healthy cognitive aging from resting-state brain activity requires further investigation.

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Gene Expression Profile in Different Age Groups and Its Association with Cognitive Function in Healthy Malay Adults in Malaysia

Cells ◽

10.3390/cells10071611 ◽

2021 ◽

Vol 10 (7) ◽

pp. 1611

Author(s):

Nur Fathiah Abdul Abdul Sani ◽

Ahmad Imran Zaydi Amir Amir Hamzah ◽

Zulzikry Hafiz Abu Abu Bakar ◽

Yasmin Anum Mohd Mohd Yusof ◽

Suzana Makpol ◽

...

Keyword(s):

Gene Expression ◽

Cognitive Decline ◽

Cognitive Aging ◽

Successful Aging ◽

Expression Patterns ◽

Age Groups ◽

Genetic Network ◽

Cross Sectional ◽

Age Related ◽

Age Related Cognitive Decline

The mechanism of cognitive aging at the molecular level is complex and not well understood. Growing evidence suggests that cognitive differences might also be caused by ethnicity. Thus, this study aims to determine the gene expression changes associated with age-related cognitive decline among Malay adults in Malaysia. A cross-sectional study was conducted on 160 healthy Malay subjects, aged between 28 and 79, and recruited around Selangor and Klang Valley, Malaysia. Gene expression analysis was performed using a HumanHT-12v4.0 Expression BeadChip microarray kit. The top 20 differentially expressed genes at p < 0.05 and fold change (FC) = 1.2 showed that PAFAH1B3, HIST1H1E, KCNA3, TM7SF2, RGS1, and TGFBRAP1 were regulated with increased age. The gene set analysis suggests that the Malay adult’s susceptibility to developing age-related cognitive decline might be due to the changes in gene expression patterns associated with inflammation, signal transduction, and metabolic pathway in the genetic network. It may, perhaps, have important implications for finding a biomarker for cognitive decline and offer molecular targets to achieve successful aging, mainly in the Malay population in Malaysia.

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Older Adults’ Recalled Memorable Messages about Aging and Their Associations with Successful Aging

Human Communication Research ◽

10.1093/hcr/hqz011 ◽

2019 ◽

Vol 45 (4) ◽

pp. 474-507 ◽

Cited By ~ 3

Author(s):

Quinten S Bernhold ◽

Howard Giles

Keyword(s):

Older Adults ◽

Successful Aging ◽

Hope Theory ◽

Memorable Messages ◽

Subjective State ◽

Age Related ◽

Dispositional Hope ◽

The Right ◽

Memorable Message

Abstract Using the Communicative Ecology Model of Successful Aging (CEMSA), this study examined how one’s own age-related communication and memorable message characteristics indirectly predict successful aging, via aging efficacy. Older adults with higher dispositional hope recalled memorable messages as (a) higher in positivity, (b) higher in efficacy, and (c) more likely to contain a theme of aging not being important or being a subjective state that can be overcome with the right mindset. Older adults were classified as engaged, bantering, or disengaged agers, based on their own age-related communication. Uniquely for CEMSA’s development and the blended role of hope theory within it, memorable message efficacy indirectly predicted greater successful aging, via heightened aging efficacy.

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Bilingual experience and executive control over the adult lifespan: The role of biological sex

Bilingualism Language and Cognition ◽

10.1017/s1366728918000317 ◽

2018 ◽

Vol 22 (04) ◽

pp. 733-751 ◽

Cited By ~ 1

Author(s):

SIVANIYA SUBRAMANIAPILLAI ◽

MARIA NATASHA RAJAH ◽

STAMATOULA PASVANIS ◽

DEBRA TITONE

Keyword(s):

Executive Control ◽

Cognitive Aging ◽

Wisconsin Card Sort Test ◽

Adult Women ◽

Language Experience ◽

Card Sort ◽

Adult Lifespan ◽

Biological Sex ◽

Age Related ◽

Improved Performance

We investigated whether bilingual language experience over the lifespan impacts women and men in a manner that differentially buffers against age-related declines in executive control. To this end, we investigated whether executive control performance in a lifespan sample of adult women and men were differentially impacted by individual differences in bilingual language experience, assessed using an unspeeded measure of executive control: the Wisconsin Card Sort Test. The results suggested that women showed both the greatest degree of age-related decline across WCST measures, and a greater likelihood than men to express improved performance as a function of increased bilingual experience. We consider implications of this finding for advancing our understanding of the relation between bilingualism and cognition, and also the effects of biological sex on cognitive aging.

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Episodic Future Thinking and Cognitive Aging

Oxford Research Encyclopedia of Psychology ◽

10.1093/acrefore/9780190236557.013.380 ◽

2018 ◽

Cited By ~ 1

Author(s):

Daniel L. Schacter ◽

Aleea L. Devitt ◽

Donna Rose Addis

Keyword(s):

Older Adults ◽

Problem Solving ◽

Episodic Memory ◽

Prospective Memory ◽

Cognitive Aging ◽

Episodic Future Thinking ◽

Future Thinking ◽

Age Related ◽

Prosocial Intentions ◽

Age Related Changes

Episodic future thinking refers to the ability to imagine or simulate experiences that might occur in an individual’s personal future. It has been known for decades that cognitive aging is associated with declines in episodic memory, and recent research has documented correlated age-related declines in episodic future thinking. Previous research has considered both cognitive and neural mechanisms that are responsible for age-related changes in episodic future thinking, as well as effects of aging on the functions served by episodic future thinking. Studies concerned with mechanism indicate that multiple cognitive mechanisms contribute to changes in episodic future thinking during aging, including episodic memory retrieval, narrative style, and executive processes. Recent studies using an episodic specificity induction—brief training in recollecting episodic details of a recent experience—have proven useful in separating the contributions of episodic retrieval from other non-episodic processes during future thinking tasks in both old and young adults. Neuroimaging studies provide preliminary evidence of a role for age-related changes in default and executive brain networks in episodic future thinking and autobiographical planning. Studies concerned with function have examined age-related effects on the link between episodic future thinking and a variety of processes, including everyday problem-solving, prospective memory, prosocial intentions, and intertemporal choice/delay discounting. The general finding in these studies is for age-related reductions, consistent with the work on mechanisms that consistently reveals reduced episodic detail in older adults when they imagine future events. However, several studies have revealed that episodic simulation nonetheless confers some benefits for tasks tapping adaptive functions in older adults, such as problem-solving, prospective memory, and prosocial intentions, even though age-related deficits on these tasks are not eliminated or reduced by episodic future thinking.

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