scholarly journals X-ray transmission grating spectrometer with CCD detector for laser plasma studies

1991 ◽  
Vol 9 (2) ◽  
pp. 579-591 ◽  
Author(s):  
L. Pína ◽  
H. Fiedorowicz ◽  
M. O. Koshevoi ◽  
A. A. Rupasov ◽  
B. Rus ◽  
...  
Keyword(s):  
Laser Plasma ◽  
Dynamic Range ◽  
High Sensitivity ◽  
Array Detector ◽  
Charge Coupled Device ◽  
X Ray ◽  
Transmission Grating ◽  
Hot Plasma ◽  
Ccd Detector ◽  
Wet Processing

A program is under way to develop methods and instrumentation based on charge-coupled device (CCD) sensors for hot plasma diagnostics. We have developed a new X-ray spectrometer in which a freestanding X-ray transmission grating is coupled to a CCD linear array detector with electronic digitized readout replacing film and its wet processing. This instrument measures time-integrated pulsed X-ray spectra with moderate spectral resolution (δλ ≤ 0.6 nm) over a broad spectral range (0.3–2 keV) with high sensitivity, linearity, and large dynamic range. The performance of the device was tested using laser plasma as the X-ray source.

A combined sinusoidal transmission grating spectrometer and x-ray diode array diagnostics for time-resolved spectral measurements in laser plasma experiments

2019 ◽  
Vol 90 (1) ◽  
pp. 013501 ◽  
Author(s):  
Ze’ev Shpilman ◽  
Gilad Hurvitz ◽  
Liron Danon ◽  
Tomer Shussman ◽  
Yosi Ehrlich ◽  
...  
Keyword(s):  
Laser Plasma ◽  
Diode Array ◽  
Spectral Measurements ◽  
Time Resolved ◽  
X Ray ◽  
Transmission Grating ◽  
Grating Spectrometer

Synchrotron Microtomography of Composites

1988 ◽  
Vol 143 ◽  
Author(s):  
S. R. Stock ◽  
J. H. Kinney ◽  
T. M. Breunig ◽  
U. Bonse ◽  
S. D. Antolovich ◽  
...  
Keyword(s):  
Charge Coupled Device ◽  
High Brightness ◽  
X Ray ◽  
Three Point Bending ◽  
Ccd Detector ◽  
The Matrix ◽  
Dimensional Distribution ◽  
X Ray Computed ◽  
Synchrotron Microtomography

AbstractX-ray computed tomography (CT) uses absorption profiles from many different viewing directions to reconstruct the two-dimensional distribution of x-ray absorptivity within a slice of the sample. The tunability, high brightness and parallelism of synchrotron radiation are critical to high resolution (0.001mm), high contrast (1%) CT or microtomography. In situ study of samples multiple times during the course of an experiment is exciting to consider.Continuous fiber SiC/Al composites were deformed under three-point bending, and the resulting damage and fiber arrangement were revealed with synchrotron microtomography. Several hundred slices of 0.012 mm thickness were recorded simultaneously using 25 key radiation and a phosphor screen/charge coupled device (CCD) detector. Reconstruction was with the filtered back projection method. Low density regions were observed in the matrix in regions of highest stress where cracking is expected.

scholarly journals Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography

Crystals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1579
Author(s):  
Omur Guven ◽  
Mehmet Gul ◽  
Esra Ayan ◽  
J Austin Johnson ◽  
Baris Cakilkaya ◽  
...  
Keyword(s):  
Data Collection ◽  
High Throughput ◽  
Drug Screening ◽  
Dynamic Range ◽  
Drug Repurposing ◽  
Low Noise ◽  
Drug Binding ◽  
Array Detector ◽  
X Ray ◽  
Main Protease

Since early 2020, COVID-19 has grown to affect the lives of billions globally. A worldwide investigation has been ongoing for characterizing the virus and also for finding an effective drug and developing vaccines. As time has been of the essence, a crucial part of this research has been drug repurposing; therefore, confirmation of in silico drug screening studies have been carried out for this purpose. Here we demonstrated the possibility of screening a variety of drugs efficiently by leveraging a high data collection rate of 120 images/second with the new low-noise, high dynamic range ePix10k2M Pixel Array Detector installed at the Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS). The X-ray Free-Electron Laser (XFEL) is used for remote high-throughput data collection for drug repurposing of the main protease (Mpro) of SARS-CoV-2 at ambient temperature with mitigated X-ray radiation damage. We obtained multiple structures soaked with nine drug candidate molecules in two crystal forms. Although our drug binding attempts failed, we successfully established a high-throughput Serial Femtosecond X-ray crystallographic (SFX) data collection protocol.

Local atomic structure analysis around Mg atom doped in GaN by X-ray absorption spectroscopy and spectrum simulations

2021 ◽  
Vol 28 (4) ◽  
Author(s):  
Noritake Isomura ◽  
Yasuji Kimoto
Keyword(s):  
Absorption Spectroscopy ◽  
Density Functional ◽  
High Sensitivity ◽  
High Energy ◽  
High Energy Resolution ◽  
Array Detector ◽  
Superconducting Tunnel Junction ◽  
Substitutional Site ◽  
X Ray ◽  
X Ray Absorption

The identification of the incorporated site of magnesium (Mg) and hydrogen (H) required for p-type formation in gallium nitride (GaN) power devices has been demonstrated by X-ray absorption spectroscopy (XAS). In this study, the fluorescence line of Mg with 3 × 1019 atoms cm−3 was successfully separated from that of Ga using a superconducting tunnel junction array detector with high sensitivity and high energy resolution, and consequently the Mg K-edge XAS spectra of such dilute samples were obtained. The site of Mg atoms incorporated into the GaN lattice was identified as the Ga substitutional site by comparing the experimental XAS spectrum with the simulated spectra calculated by density functional theory. In addition, the presence or absence of H around Mg can be determined through distinctive characteristics expected from the spectrum simulations.

Sample Treatment for TXRF - Requirements and Prospects

1988 ◽  
Vol 32 ◽  
pp. 211-220 ◽  
Author(s):  
Andreas Prange ◽  
Heinrich Schwenke
Keyword(s):  
Water Quality ◽  
Air Pollution ◽  
Dynamic Range ◽  
Water Quality Management ◽  
High Sensitivity ◽  
Total Reflection ◽  
Sample Treatment ◽  
Wide Dynamic Range ◽  
X Ray ◽  
And Performance

Total-reflection X-ray fluorescence spectrometry, abbreviated as TXRF, is known for its high sensitivity down to the low pg-level or sub-ppb level, respectively, and its wide dynamic range of about three to four orders of magnitude (Yoneda and Horiuchi, 1971, Wobrauschek and Aiginger, 1980; Knoth and Schwenke, 1978 and 1980, Aiginger and Wobrausohek, 1985, Michaelis et al., 1985, Prange, 1987). Meanwhile several laboratories have purchased commercially available TXRF spectrometers and have started to report favourable about this technique. Applications have been reported from various disciplines: These are estuarine and marine water quality management and research, air pollution studies, mineralogical investigations, biology and medicine (Prange, 1987, Prange et al, 1985; Prange and Kremling, 1985, Prange et al., 1987, Stöβel and Prange, 1985, Michaelis, 1986, Ketelsen and Knöchel, 1985, Leland et al., 1987, von Bohlen et al., 1987, Junge et al., 1983, Hentschke et al., 1985, Hentschke et al., 1985, Gerwinski and Goetz, 1987, von Bohlen et al., 1987), In spite of its close kinship to conventional EDXRF , TXRF is quite different with respect to operation and performance and provides complementary capabilities.

Application of Imaging Plate for X-Ray Diffractometry

1991 ◽  
Vol 35 (A) ◽  
pp. 407-413 ◽  
Author(s):  
Atsushi Shibata ◽  
Katsunari Sasaki ◽  
Takao Kinefuchi
Keyword(s):  
Structure Analysis ◽  
Dynamic Range ◽  
Imaging System ◽  
High Sensitivity ◽  
Effective Area ◽  
Superior Performance ◽  
Imaging Plate ◽  
X Ray ◽  
X Ray Imaging ◽  
Electric Device

AbstractThe Fuji Imaging Plate (IP) is a 2-dimensional detector in which a latent X-ray image is stored as a distribution of color centers on a photostimulable phosphor (BaFBr:Eu2+) screen. It has a large effective area, wide dynamic range and high sensitivity. Thus it has been widely used not only in medical but also in scientific and industrial fields. Particularly in X-ray structure analysis, mainly of proteins, it has been used extensively and achieved good results.On the other hand, few applications have been reported in the field except for structure analysis, in spite of the superior performance of the IP which will give significant advantages in various measurements which have been done using an X-ray film such as electric device and fiber specimen.Therefore we report here the basic performance of R-AXIS II(Rigaku Automated X-Ray Imaging System II), an IP reader made by Rigaku, and some applications of X-ray diffraction measurements using IP.

Direct Observation of Diffraction Arcs from Nanoscale Precipitates in Steels by Highly Brilliant and Focused Synchrotron Radiation Beam and Imaging Plate

1994 ◽  
Vol 332 ◽  
Author(s):  
Yasuo Takagi ◽  
Yoshitaka Okitsu ◽  
Toshiyasu Ukena
Keyword(s):  
Synchrotron Radiation ◽  
Direct Observation ◽  
Dynamic Range ◽  
High Sensitivity ◽  
Imaging Plate ◽  
Synchrotron Radiation Beam ◽  
Radiation Beam ◽  
X Ray ◽  
The Matrix ◽  
First Time

ABSTRACTDirect observation of diffraction arcs by X-ray from nanoscale precipitates in steels has become possible for the first time by using a highly brilliant and focused synchrotron radiation beam at BL3A of Photon Factory, and also by using an “imaging plate”, a two dimensional X-ray detector which has a wide dynamic range and high sensitivity. For examples, most of the diffraction arcs from ε-Cu precipitates (∼200 Å in diameter and ∼1 at. % in concentration) in Cu-added steels were observed. The method can apply to nondestructive and in-situ observation of creation and growth processes of the precipitates which has close relationships to various physical properties of the matrix steels.

scholarly journals Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography

2021 ◽  
Author(s):  
Omur Guven ◽  
Mehmet Gul ◽  
Esra Ayan ◽  
J. Austin Johnson ◽  
Baris Cakilkaya ◽  
...  
Keyword(s):  
Data Collection ◽  
High Throughput ◽  
Drug Screening ◽  
Dynamic Range ◽  
Drug Repurposing ◽  
Low Noise ◽  
Drug Binding ◽  
Array Detector ◽  
X Ray ◽  
Main Protease

Since early 2020, COVID-19 has grown to affect the lives of billions globally. A worldwide investigation has been ongoing for characterizing the virus and also for finding an effective drug and developing vaccines. As time has been of the essence, a crucial part of this research has been drug repurposing; therefore, confirmation of in-silico drug screening studies have been carried out for this purpose. Here we demonstrated the possibility of screening a variety of drugs efficiently by leveraging a high data collection rate of 120 images/second with the new low-noise, high dynamic range ePix10k2M Pixel Array Detector installed at the Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS). The X-ray Free-Electron Laser (XFEL) is used for remote high-throughput data collection for drug repurposing of the main protease (Mpro) of SARS-CoV-2 at ambient temperature with mitigated X-ray radiation damage. We obtained multiple high-resolution structures soaked with 9 drug candidate molecules in two crystal forms. Although our drug binding attempts failed, we successfully established a high-throughput Serial Femtosecond X-ray crystallographic (SFX) data collection protocol.

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