Cilia Microtubule Deformation: A Preliminary Report
Various hypotheses for the mechanism of ciliar motility either purport or oppose the concept of microtubule contraction. Recent literature supporting the Sliding Microtubule Model has established that microtubule doublets move relative to one another during the process of bending. Satir (1968) concluded that there is no change of length in the doublets during bending of cilia. He based his conclusion upon: (1) circular relationships and (2) a two dimensional configuration of the microtubules. Accuracy of the circular relationships is dependent upon how close the approximation is to the true curvilinear relationship expressed by a ciliutn. Cross sectional rotation during bending may limit the validity of two dimensional analysis. This communication is a preliminary report on a new, three dimensional approach for determining the deformational characteristics of elongation or shortening of microtubules as they may be expressed in cilia.