Research Methodologic Issues in Evaluating Behavioral Disturbances of Dementia

1996 ◽  
Vol 8 (S2) ◽  
pp. 149-150 ◽  
Author(s):  
Sanford I. Finkel
Keyword(s):  
Quality Of Life ◽  
Behavioral Problems ◽  
Neuropsychiatric Symptoms ◽  
Healthcare Providers ◽  
Case Description ◽  
Behavioral Disturbances ◽  
Policy Makers ◽  
Societal Costs ◽  
Intrinsic Component

Behavioral disturbances of dementia have been noted by early researchers in the field, including Esquirol (1838) and Alzheimer in his seminal case description (1907). Increasingly, family members, healthcare providers, and policy makers are realizing that neuropsychiatric symptoms and behavioral problems are an intrinsic component of Alzheimer's disease and result in caregiver psychopathology, early institutionalization, substantial societal costs, and detriment in the quality of life for the patient and caregivers.

Depression, Anxiety, and Sleep Disturbances

1997 ◽  
Vol 8 (S3) ◽  
pp. 415-418 ◽  
Author(s):  
Burton V. Reifler
Keyword(s):  
Quality Of Life ◽  
Family Member ◽  
Behavioral Problems ◽  
Sleep Disturbances ◽  
Current Knowledge ◽  
Behavioral Disturbances ◽  
Appropriate Treatment ◽  
Considerable Impact

Of the numerous behavioral disturbances identified in patients with dementia, depression, anxiety, and sleep disturbances can have a considerable impact on the quality of life of both the patient and the caregiver, particularly if the caregiver is a family member. Our task as clinicians is to identify the most appropriate treatment based on current knowledge of these behavioral problems.

scholarly journals Neuropsychiatric Symptom Clusters and Quality of Life Among Patients With Stroke

2019 ◽  
Vol 42 (2) ◽  
pp. 1-11
Author(s):  
Vachira Posai ◽  
Ploenta Pipatsombat ◽  
Pramote Thangkratok
Keyword(s):  
Quality Of Life ◽  
Behavioral Problems ◽  
Neuropsychiatric Symptoms ◽  
Clinical Information ◽  
Average Frequency ◽  
Neuropsychiatric Symptom ◽  
Symptom Clusters ◽  
Mood Disturbance ◽  
Quality Of Life Scale

Background: There are relatively few reports of neuropsychiatric symptom clusters which affect the quality of life in patients with stroke.Objective: To study neuropsychiatric symptom clusters and the relationship between neuropsychiatric symptom clusters and quality of life among patients with stroke.Methods: This descriptive study conducted in 140 patients with stroke at Sanpasithiprasong Hospital, Ubon Ratchathani, Thailand; they were selected purposively. Data were collected through patient general and clinical information, the neuropsychiatric symptoms assessment, and the 12-item stroke-specific quality of life scale conducted from September 2018 to January 2019. Results: The results illustrated that 12 neuropsychiatric symptoms of patients with stroke embraced 3 symptom clusters were psychosis clusters, behavioral problems clusters, and mood disturbance clusters. (average frequency = 1.58, 2.37, 2.49; and average severity = 2.08, 2.73, 2.82, respectively). Among 3 symptom clusters, psychosis (r = 0.289; P < .01), behavioral problems (r = 0.719; P < .01), and mood disturbance (r = 0.716; P < .01) clusters were statistically significantly associated with all aspects of quality of life.Conclusions: This study showed that neuropsychiatric symptom, especially behavioral problems and mood disturbance clusters were correlated with quality of life among patients with stroke.

scholarly journals The International/Canadian Hereditary Angioedema Guideline

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Stephen Betschel ◽  
Jacquie Badiou ◽  
Karen Binkley ◽  
Rozita Borici-Mazi ◽  
Jacques Hébert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hereditary Angioedema ◽  
Primary Care Physicians ◽  
Healthcare Providers ◽  
Upper Airway ◽  
Self Administration ◽  
Policy Makers ◽  
Individualized Care ◽  
Related Quality

AbstractThis is an update to the 2014 Canadian Hereditary Angioedema Guideline with an expanded scope to include the management of hereditary angioedema (HAE) patients worldwide. It is a collaboration of Canadian and international HAE experts and patient groups led by the Canadian Hereditary Angioedema Network. The objective of this guideline is to provide evidence-based recommendations, using the GRADE system, for the management of patients with HAE. This includes the treatment of attacks, short-term prophylaxis, long-term prophylaxis, and recommendations for self-administration, individualized therapy, quality of life, and comprehensive care. New to the 2019 version of this guideline are sections covering the diagnosis and recommended therapies for acute treatment in HAE patients with normal C1-INH, as well as sections on pregnant and paediatric patients, patient associations and an HAE registry. Hereditary angioedema results in random and often unpredictable attacks of painful swelling typically affecting the extremities, bowel mucosa, genitals, face and upper airway. Attacks are associated with significant functional impairment, decreased health-related quality of life, and mortality in the case of laryngeal attacks. Caring for patients with HAE can be challenging due to the complexity of this disease. The care of patients with HAE in Canada, as in many countries, continues to be neither optimal nor uniform. It lags behind some other countries where there are more organized models for HAE management, and greater availability of additional licensed therapeutic options. It is anticipated that providing this guideline to caregivers, policy makers, patients, and advocates will not only optimize the management of HAE, but also promote the importance of individualized care. The primary target users of this guideline are healthcare providers who are managing patients with HAE. Other healthcare providers who may use this guideline are emergency and intensive care physicians, primary care physicians, gastroenterologists, dentists, otolaryngologists, paediatricians, and gynaecologists who will encounter patients with HAE and need to be aware of this condition. Hospital administrators, insurers and policy makers may also find this guideline helpful.

Nursing Home Research From Investigators' Perspective

1997 ◽  
Vol 8 (S3) ◽  
pp. 371-373
Author(s):  
Sanford I. Finkel ◽  
John Lyons
Keyword(s):  
Quality Of Life ◽  
Nursing Home ◽  
Nursing Homes ◽  
Family Caregivers ◽  
Behavioral Problems ◽  
Negative Effects ◽  
Behavioral Disturbances ◽  
Behaviorally Disturbed

The negative effects of behavioral disturbances of dementia on the quality of life of both the patient and caregiver have been recognized for some time. For family caregivers, behavioral problems increase stress and may lead to institutionalization of the patient. In nursing homes, professional caregivers may have difficulty managing behaviorally disturbed patients and avoid interactions with them.

scholarly journals Non-Pharmacologic Interventions for Caregivers of People With Dementia in Latin America: A Review

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 275-276
Author(s):  
Jose Aravena ◽  
Jean Gajardo ◽  
Laura Gitlin
Keyword(s):  
Quality Of Life ◽  
Latin America ◽  
Depressive Symptoms ◽  
Latin American ◽  
Randomized Clinical Trials ◽  
Social Inequalities ◽  
Neuropsychiatric Symptoms ◽  
People With Dementia ◽  
Person With Dementia

Abstract In a scenario of increasing longevity and social inequalities, Latin-America is an important contributor to the worldwide dementia burden. Caregivers’ health is fundamental to maintain the person with dementia quality of life. However, caregiving is a culturally sensible role that requires tailored solutions. The aim is to synthesize the evidence about non-pharmacologic interventions targeted to caregivers of people with dementia in Latin-American contexts. A comprehensive review of interventions in caregivers and persons with dementia in Latin-American countries was conducted using MEDLINE, Embase, PsycINFO, and Scopus with studies published until January 27th, 2020. Randomized clinical trials of non-pharmacologic interventions targeted to caregivers of people with dementia or dyads where included. Qualitative synthesis of the evidence was presented and analyzed. Overall, 9 pilot RCT were included for the final analysis (6 Brazil, 1 Colombia, 1 Mexico, 1 Perú). The biggest study recruited 69 caregivers and the smallest 13 dyads, with follow-up range of 3-6 months. 5 control groups received at least some other non-standard care type of intervention. 8 were targeted exclusively to caregivers (4 group intervention, 3 individual, and 1 combined) and 1 multicomponent intervention. Most frequent measured outcomes were caregiver’s burden, anxiety, depressive symptoms, and quality of life, and person with dementia neuropsychiatric symptoms. Individual interventions report better results in caregiver parameters such as burden and depressive symptoms and person with dementia neuropsychiatric symptoms. Group interventions presented mixed results. Nevertheless, the quality of evidence was low. There is a critical need to study interventions for caregivers in Latin-American contexts.

The societal costs and quality of life of patients suffering from bipolar disorder in the Netherlands

2004 ◽  
Vol 110 (5) ◽  
pp. 383-392 ◽  
Author(s):  
L. Hakkaart-van Roijen ◽  
M. B. Hoeijenbos ◽  
E. J. Regeer ◽  
M. ten Have ◽  
W. A. Nolen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bipolar Disorder ◽  
The Netherlands ◽  
Societal Costs

Neuropsychiatric symptoms, seizure severity, employment, and quality of life of Jordanians with epilepsy

2013 ◽  
Vol 27 (1) ◽  
pp. 272-275 ◽  
Author(s):  
H. Hamid ◽  
A.S. Kasasbeh ◽  
M.J. Suleiman ◽  
X. Cong ◽  
H. Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neuropsychiatric Symptoms ◽  
Seizure Severity

scholarly journals Assessment of neuropsychiatric symptoms in dementia: Toward improving accuracy

2013 ◽  
Vol 7 (3) ◽  
pp. 244-251 ◽  
Author(s):  
Florindo Stella
Keyword(s):  
Rating Scale ◽  
High Reliability ◽  
Neuropsychiatric Symptoms ◽  
Clinical Approach ◽  
Behavioral Disturbances ◽  
Versatile Tool ◽  
Clinician Rating ◽  
Improving Accuracy ◽  
Elderly Caregivers

ABSTRACT The issue of this article concerned the discussion about tools frequently used tools for assessing neuropsychiatric symptoms of patients with dementia, particularly Alzheimer's disease. The aims were to discuss the main tools for evaluating behavioral disturbances, and particularly the accuracy of the Neuropsychiatric Inventory - Clinician Rating Scale (NPI-C). The clinical approach to and diagnosis of neuropsychiatric syndromes in dementia require suitable accuracy. Advances in the recognition and early accurate diagnosis of psychopathological symptoms help guide appropriate pharmacological and non-pharmacological interventions. In addition, recommended standardized and validated measurements contribute to both scientific research and clinical practice. Emotional distress, caregiver burden, and cognitive impairment often experienced by elderly caregivers, may affect the quality of caregiver reports. The clinician rating approach helps attenuate these misinterpretations. In this scenario, the NPI-C is a promising and versatile tool for assessing neuropsychiatric syndromes in dementia, offering good accuracy and high reliability, mainly based on the diagnostic impression of the clinician. This tool can provide both strategies: a comprehensive assessment of neuropsychiatric symptoms in dementia or the investigation of specific psychopathological syndromes such as agitation, depression, anxiety, apathy, sleep disorders, and aberrant motor disorders, among others.

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