scholarly journals ON SIMON NELSON PATTEN’S PROGRESSIVISM: A NOTE

Author(s):  
Luca Fiorito ◽  
Massimiliano Vatiero

This article is an attempt to offer an assessment of the main coordinates of Simon Nelson Patten’s views on democracy and biological determinism. This will allow us to better delineate the differences—as well as the affinities—between Patten and the core of progressives discussed by Thomas C. Leonard in a series of path-breaking contributions, culminating in his Illiberal Reformers: Race, Eugenics, and American Economics in the Progressive Era. It is our contention that even within the persisting intricacies, ambiguities, and contradictions of Patten’s expository style, it is possible to trace a shift in some aspects of his ideas—a gradual evolution that makes his peculiar brand of progressivism different from that of his most “illiberal” counterparts.

2020 ◽  
Author(s):  
Luca Fiorito ◽  
Massimiliano Vatiero

This note is an attempt to offer a somewhat more comprehensive assessment of Patten’s views on individual rights, poverty and social efficiency, as well his ideas on eugenics, biological determinism, and immigration. This will allow us to better delineate the differences—as well as the affinities—between Patten and the core of progressives recently discussed by Thomas C. Leonard in his acclaimed Illiberal Reformers. It is our contention that even within the persisting intricacies, ambiguities and contradictions of Patten’s expository style it is possible to trace a shift in some aspects of his ideas—a gradual evolution which makes his peculiar brand of progressivism different from that of his most “illiberal” counterparts.


Author(s):  
Robyn Archer

Dragan Klaić’s faith in festivals as a uniting cultural force seems to have had much in common with the altruistic beginnings of the Edinburgh Festival. While it is true that post-war Edinburgh desperately needed new economic drivers, there is no reason to doubt the founders’ desires for a cultural framework that might help to pull Europe together again. Klaić’s desire was to deconstruct the silos of national identity and construct in their place platforms on which the differences in language and practice could be better understood and shared. While Melina Mercuri’s desires for better understanding between the different cultures of Europe resulted in many positive collaborations and much-needed sources of mobility for artists through the European Capital of Culture programme, the programme has also bred a kind of necessary civic bragging that I doubt Klaić would have found productive. This account of international arts festivals in Australia is less one of bragging (though that too has had its place) and more one of early ignorance, gradual evolution and a happy present. International arts festivals in Australia were first built entirely on the Edinburgh model. When first Perth in Western Australia, and then Adelaide in South Australia, cloned that model to their relatively isolated cities, the core desire was to bring ‘culture’ to those cities. Not that Perth and Adelaide lacked artists and performances, but those who had been to Edinburgh felt that Australian audiences were rarely exposed to the ‘best’ of culture. The significantly named Elizabethan Theatre Trust and entrepreneurs such as Ken Brodziak, already toured international shows and artists: I myself was taken by our science teacher, along with a few fellow students, to see Vivien Leigh play Portia in The Merchant of Venice, in 1962.


2021 ◽  
pp. 147892992110318
Author(s):  
Matthew Flinders

Robert Putman’s The Upswing (written with Shaylyn Romney Garrett) provides a powerful meta-analysis of American social, political, economic and cultural change throughout the twentieth century. What this analysis reveals is the existence of an almost perfect arc of social progress which begins from a low position around the Gilded Age at the beginning of the twentieth century and then climbs across all variables until reaching a highpoint around 1960. The Progressive Era, Putnam argues, engineered an ‘upswing’ against inequality, polarisation, social disarray and a culture of self-centredness. Since then, however, the data suggest that a severe downswing has occurred which explains the existence of deep divisions and polarised politics in the United States. Putnam’s core argument is simple: The United States has pulled itself out of a trough before and it can do it again. In a post-Trump context, this argument could hardly be more welcome which may explain the rave reviews this book has generally received. Nevertheless, the core weakness of The Upswing is that it arguably tells us far more about how the United States ‘came together a century ago’ but far less about how it ‘can do it again’ in the future.


Cells ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 1675 ◽  
Author(s):  
Oleg V. Bylino ◽  
Airat N. Ibragimov ◽  
Yulii V. Shidlovskii

The genomes of all organisms abound with various cis-regulatory elements, which control gene activity. Transcriptional enhancers are a key group of such elements in eukaryotes and are DNA regions that form physical contacts with gene promoters and precisely orchestrate gene expression programs. Here, we follow gradual evolution of this regulatory system and discuss its features in different organisms. In eubacteria, an enhancer-like element is often a single regulatory element, is usually proximal to the core promoter, and is occupied by one or a few activators. Activation of gene expression in archaea is accompanied by the recruitment of an activator to several enhancer-like sites in the upstream promoter region. In eukaryotes, activation of expression is accompanied by the recruitment of activators to multiple enhancers, which may be distant from the core promoter, and the activators act through coactivators. The role of the general DNA architecture in transcription control increases in evolution. As a whole, it can be seen that enhancers of multicellular eukaryotes evolved from the corresponding prototypic enhancer-like regulatory elements with the gradually increasing genome size of organisms.


2017 ◽  
Vol 41 (1) ◽  
pp. 112-135 ◽  
Author(s):  
Anna Stetsenko

Research on disrupting inequality in education can benefit from situating it within the debates on varying and often conflicting meanings of equality and its perils and promises. Especially in the wake of achievement testing and resurgent biological determinism, researchers continue to equivocate between commitment to the idea that all humans are equal in their core capacities versus the tendency to attribute developmental outcomes to differences in “natural” inborn talents and endowments. This chapter examines contemporary research and theorizing to address the tenet of fundamental equality to counter biological determinism laden with mythic racial, gender, and other types of unproven assumptions and biases. Drawing on a wide range of emerging positions and evidence across neurosciences, epigenetics, developmental systems perspective, and cultural-historical framework, the core argument is that all persons have infinite potential—incalculable in advance, unlimited, and not predefined in terms of any putatively inborn “endowments.” This potential is realized in the course of activity-dependent generation of open-ended, dynamic, and situated developmental processes that are critically reliant upon sociocultural supports, tools, mediations, and access to requisite resources, especially through education. An educational policy along these lines would be centrally premised on the imperative to remedy the effects of discrimination and marginalization.


2019 ◽  
Vol 42 ◽  
Author(s):  
Guido Gainotti

Abstract The target article carefully describes the memory system, centered on the temporal lobe that builds specific memory traces. It does not, however, mention the laterality effects that exist within this system. This commentary briefly surveys evidence showing that clear asymmetries exist within the temporal lobe structures subserving the core system and that the right temporal structures mainly underpin face familiarity feelings.


Author(s):  
T. Kanetaka ◽  
M. Cho ◽  
S. Kawamura ◽  
T. Sado ◽  
K. Hara

The authors have investigated the dissolution process of human cholesterol gallstones using a scanning electron microscope(SEM). This study was carried out by comparing control gallstones incubated in beagle bile with gallstones obtained from patients who were treated with chenodeoxycholic acid(CDCA).The cholesterol gallstones for this study were obtained from 14 patients. Three control patients were treated without CDCA and eleven patients were treated with CDCA 300-600 mg/day for periods ranging from four to twenty five months. It was confirmed through chemical analysis that these gallstones contained more than 80% cholesterol in both the outer surface and the core.The specimen were obtained from the outer surface and the core of the gallstones. Each specimen was attached to alminum sheet and coated with carbon to 100Å thickness. The SEM observation was made by Hitachi S-550 with 20 kV acceleration voltage and with 60-20, 000X magnification.


Author(s):  
M. Locke ◽  
J. T. McMahon

The fat body of insects has always been compared functionally to the liver of vertebrates. Both synthesize and store glycogen and lipid and are concerned with the formation of blood proteins. The comparison becomes even more apt with the discovery of microbodies and the localization of urate oxidase and catalase in insect fat body.The microbodies are oval to spherical bodies about 1μ across with a depression and dense core on one side. The core is made of coiled tubules together with dense material close to the depressed membrane. The tubules may appear loose or densely packed but always intertwined like liquid crystals, never straight as in solid crystals (Fig. 1). When fat body is reacted with diaminobenzidine free base and H2O2 at pH 9.0 to determine the distribution of catalase, electron microscopy shows the enzyme in the matrix of the microbodies (Fig. 2). The reaction is abolished by 3-amino-1, 2, 4-triazole, a competitive inhibitor of catalase. The fat body is the only tissue which consistantly reacts positively for urate oxidase. The reaction product is sharply localized in granules of about the same size and distribution as the microbodies. The reaction is inhibited by 2, 6, 8-trichloropurine, a competitive inhibitor of urate oxidase.


Author(s):  
P.P.K. Smith

Grains of pigeonite, a calcium-poor silicate mineral of the pyroxene group, from the Whin Sill dolerite have been ion-thinned and examined by TEM. The pigeonite is strongly zoned chemically from the composition Wo8En64FS28 in the core to Wo13En34FS53 at the rim. Two phase transformations have occurred during the cooling of this pigeonite:- exsolution of augite, a more calcic pyroxene, and inversion of the pigeonite from the high- temperature C face-centred form to the low-temperature primitive form, with the formation of antiphase boundaries (APB's). Different sequences of these exsolution and inversion reactions, together with different nucleation mechanisms of the augite, have created three distinct microstructures depending on the position in the grain.In the core of the grains small platelets of augite about 0.02μm thick have farmed parallel to the (001) plane (Fig. 1). These are thought to have exsolved by homogeneous nucleation. Subsequently the inversion of the pigeonite has led to the creation of APB's.


Author(s):  
Philip D. Lunger ◽  
H. Fred Clark

In the course of fine structure studies of spontaneous “C-type” particle production in a viper (Vipera russelli) spleen cell line, designated VSW, virus particles were frequently observed within mitochondria. The latter were usually enlarged or swollen, compared to virus-free mitochondria, and displayed a considerable degree of cristae disorganization.Intramitochondrial viruses measure 90 to 100 mμ in diameter, and consist of a nucleoid or core region of varying density and measuring approximately 45 mμ in diameter. Nucleoid density variation is presumed to reflect varying degrees of condensation, and hence maturation stages. The core region is surrounded by a less-dense outer zone presumably representing viral capsid.Particles are usually situated in peripheral regions of the mitochondrion. In most instances they appear to be lodged between loosely apposed inner and outer mitochondrial membranes.


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