scholarly journals Editorial: Systematic reviews reveal a need for more, better data to inform antimicrobial stewardship practices in animal agriculture

2019 ◽  
Vol 20 (2) ◽  
pp. 103-105
Author(s):  
Jan M. Sargeant ◽  
Annette M. O'Connor ◽  
Charlotte B. Winder

AbstractThis editorial summarizes the key observations from a special issue of Animal Health Research Reviews comprising 14 articles related to the efficacy of antimicrobial and non-antimicrobial approaches to reduce disease in beef, dairy cattle, swine, and broiler chickens. The articles used evidence-based methods, including scoping reviews, systematic reviews, meta-analyses, and network meta-analyses. Despite finding evidence of efficacy for some of the interventions examined, across the body of research, there was a lack of replication and inconsistency in outcomes among the included trials, and concerns related to completeness of reporting and trial design and execution. There is an urgent need for more and better data to inform antimicrobial stewardship practices in animal agriculture.

2021 ◽  
Author(s):  
Rossella Martarelli ◽  
Georgia Casanova ◽  
Giovanni Lamura

Abstract BackgroundPopulation ageing, constantly on the increase in all countries worldwide, has long been the object of scientific research from several perspectives, including multi and interdisciplinary approaches. This scoping review aims to investigate the socio-economic consequences of older people’s poor health on their own economic conditions and those of their families. This study aims to: a) map the main concepts that characterise the body of literature pertaining to this issue; b) identify conceptual gaps or unexplored research areas to be addressed; c) delve into the ways of arguing about the difficulties that affect a large number of families with older members to care for, especially with regard to the concept of socio-economic deprivation, which in our perspective includes both material and social deprivation (e.g. in the form of loneliness experienced as a consequence of health disorders). This protocol fulfils the purpose of clarifying the stages and methods of the study and listing the techniques used.MethodsThis article is being drafted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses for Protocols 2015 (PRISMA-P 2015). The rationale behind the study and its stages are aligned with the guidelines of Lockwood et al. (2019) and the recommendations of Munn et al. (2018): Each stage links up with the next, according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (the 2020 PRISMA Statement), while the reporting phase refers to the Joanna Briggs Institute (JBI) checklist. The search process is being performed by means of databases such as PubMed, Scopus and Web of Science. The latest version of MAXQDA will be used for analyzing all data.Discussion We aim to highlight and connect the most useful insights addressed to stakeholders and policymakers and, most of all, the ones valuable to social innovation. Nevertheless, it is necessary for us to remark that, despite the prevalence of the English language, most research articles are written and published in other languages. Therefore, they are excluded from the search process.Systematic review registration Open Science Framework (OSF), https://osf.io/xq58z Registration DOI: 10.17605/OSF.IO/XQ58Z


2021 ◽  
Vol 37 (5) ◽  
pp. 421-434
Author(s):  
Susana Pereira Costa ◽  
◽  
Inês Lopes Antunes ◽  
Ana Margarida Gomes ◽  
Cláudia Ho ◽  
...  

Objetivos: Resumir as informações publicadas acerca dos problemas de coagulação em adultos com SARS-CoV-2, incluindo características, fisiopatologia, diagnóstico e resposta ao uso profilático ou terapêutico de anticoagulantes ou antiagregantes plaquetários. Métodos: Realizada uma revisão abrangente, de acordo com as guidelines Joanna Briggs Institute Guidelines on Scoping Reviews e Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review guidelines (PRISMA-ScR). Efetuada pesquisa nas bases de dados MEDLINE®, SciELO® e Web of Science® entre 1 e 2 de maio de 2020. A seleção dos artigos foi dividida em etapas sequenciais considerando: título, resumo e artigo integral. Em cada etapa os artigos foram aceites ou rejeitados tendo em conta os critérios de inclusão e exclusão. Foi feito o mapeamento dos dados e a evidência relevante foi sumarizada. Resultados: Após seleção obtiveram-se 106 artigos. Destes, 36 correspondiam a cartas, 28 a estudos originais, 25 a revisões e 14 a relatos de caso; uma meta-análise, um comentário e um consenso também foram incluídos. Os resultados mostraram associação entre COVID-19 e complicações trombóticas, embora com diferentes tipos de eventos e taxas de frequência. A tríade inflamação, disfunção endotelial e coagulopatia parecem estar subjacentes às alterações fisiopatológicas. As técnicas laboratoriais e de imagem podem ser úteis para uma intervenção adequada. A profilaxia com anticoagulantes parentéricos, preferencialmente heparina de baixo peso molecular (HBPM) em dose intermédia, entre as comummente utilizadas para profilaxia ou tratamento, está indicada em pacientes hospitalizados, especialmente com doença grave. Deve ser mantida por um período variável após a alta, dependendo do doente. A anticoagulação terapêutica parece não diferir de outras situações previamente conhecidas. Conclusões: Várias incertezas persistem na abordagem dos problemas da coagulação em pacientes com infeção por SARS-CoV-2. As informações existentes dizem respeito principalmente ao contexto hospitalar e têm origem em fontes pouco robustas. Assim, são necessários ensaios clínicos aleatorizados e controlados para sustentar as decisões clínicas em todos os estadios.


Medwave ◽  
2021 ◽  
Vol 21 (02) ◽  
pp. e8144-e8144
Author(s):  
Catalina Verdejo ◽  
Luis Tapia-Benavente ◽  
Bastián Schuller-Martínez ◽  
Laura Vergara-Merino ◽  
Manuel Vargas-Peirano ◽  
...  

The increasing amount of evidence has caused an increasing amount of literature reviews. There are different types of reviews —systematic reviews are the best known—, and every type of review has different purposes. The scoping review is a recent model that aims to answer broad questions and identify and expose the available evidence for a broader question, using a rigorous and reproducible method. In the last two decades, researchers have discussed the most appropriate method to carry out scoping reviews, and recently the “Preferred Reporting Items for Systematic Reviews and Meta-Analyses’ for scoping reviews (PRISMA-ScR) reporting guideline was published. This is the fifth article of a methodological collaborative series of narrative reviews about general topics on biostatistics and clinical epidemiology. This review aims to describe what scoping reviews are, identify their objectives, differentiate them from other types of reviews, and provide considerations on how to carry them out.


Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4015
Author(s):  
Sohei Satoi

This special issue, “Surgical Treatment of Pancreatic Ductal Adenocarcinoma” contains 13 articles (five original articles, five reviews, and three systematic reviews/meta-analyses) authored by international leaders and surgeons who treat patients with pancreatic ductal adenocarcinoma (PDAC) [...]


2022 ◽  
Vol 9 ◽  
Author(s):  
Rodolfo Castro ◽  
Marcelo Ribeiro-Alves ◽  
Cátia Oliveira ◽  
Carmen Phang Romero ◽  
Hugo Perazzo ◽  
...  

Background: Lifestyle Medicine (LM) aims to address six main behavioral domains: diet/nutrition, substance use (SU), physical activity (PA), social relationships, stress management, and sleep. Digital Health Interventions (DHIs) have been used to improve these domains. However, there is no consensus on how to measure lifestyle and its intermediate outcomes aside from measuring each behavior separately. We aimed to describe (1) the most frequent lifestyle domains addressed by DHIs, (2) the most frequent outcomes used to measure lifestyle changes, and (3) the most frequent DHI delivery methods.Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-ScR) Extension for Scoping Reviews. A literature search was conducted using MEDLINE, Cochrane Library, EMBASE, and Web of Science for publications since 2010. We included systematic reviews and meta-analyses of clinical trials using DHI to promote health, behavioral, or lifestyle change.Results: Overall, 954 records were identified, and 72 systematic reviews were included. Of those, 35 conducted meta-analyses, 58 addressed diet/nutrition, and 60 focused on PA. Only one systematic review evaluated all six lifestyle domains simultaneously; 1 systematic review evaluated five lifestyle domains; 5 systematic reviews evaluated 4 lifestyle domains; 14 systematic reviews evaluated 3 lifestyle domains; and the remaining 52 systematic reviews evaluated only one or two domains. The most frequently evaluated domains were diet/nutrition and PA. The most frequent DHI delivery methods were smartphone apps and websites.Discussion: The concept of lifestyle is still unclear and fragmented, making it hard to evaluate the complex interconnections of unhealthy behaviors, and their impact on health. Clarifying this concept, refining its operationalization, and defining the reporting guidelines should be considered as the current research priorities. DHIs have the potential to improve lifestyle at primary, secondary, and tertiary levels of prevention—but most of them are targeting clinical populations. Although important advances have been made to evaluate DHIs, some of their characteristics, such as the rate at which they become obsolete, will require innovative research designs to evaluate long-term outcomes in health.


Author(s):  
Andreia Mesquita ◽  
Diana Santos ◽  
Vítor Raposo

Enquadramento: a implementação da gestão do conhecimento nas organizações hospitalares é considerada um elemento essencial de uma boa governação, que permite dar resposta aos desafios que surgem diariamente com maior facilidade, efetividade e eficiência. Contudo, existem inúmeros fatores influenciadores da implementação deste conceito de interesse nas organizações hospitalares, sendo pertinente identificá-los. Objetivo: mapear os fatores que influenciam a implementação da gestão do conhecimento no contexto hospitalar pelos clínicos e pelos gestores em saúde. Metodologia: scoping review realizada segundo: Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Foi realizada uma pesquisa em bases de dados científicas sem restrição ao espaço temporal e nos idiomas português, inglês e espanhol. O processo de seleção de estudos, extração de dados e síntese da informação foi concretizado apenas por um autor. Resultados: através dos quatro estudos incluídos nesta revisão, foi possível identificar 16 fatores influenciadores da implementação da gestão do conhecimento em contexto hospitalar pelos clínicos e gestores em saúde. Conclusão: o mapeamento dos fatores influenciadores permite o desenvolvimento de estratégias organizacionais para potenciar ou colmatar os mesmos, tendo em vista ganhos em saúde e uma boa governação hospitalar. Também serão necessários mais estudos primários, essencialmente em contexto português


PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0119892 ◽  
Author(s):  
Christian B. van der Pol ◽  
Matthew D. F. McInnes ◽  
William Petrcich ◽  
Adam S. Tunis ◽  
Ramez Hanna

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e036937
Author(s):  
Amanda M Midboe ◽  
Caroline Gray ◽  
Hannah Cheng ◽  
Leonore Okwara ◽  
Randall C Gale

IntroductionVulnerable populations face significant challenges in navigating the care continuum, ranging from diagnosis of illness to linkage and retention in healthcare. Understanding how best to move individuals within these vulnerable populations across the care continuum is critical to improving their health. A large body of literature has focused on evaluation of implementation of various health-focused interventions in this population. However, we do not fully understand the unique challenges to implementing healthcare interventions for vulnerable populations. This study aims to examine the literature describing implementation of health service interventions among vulnerable populations to identify how implementations using the Consolidated Framework for Implementation Research are adapted. Findings from this review will be useful to implementation scientists to identify gaps in evidence and for adapting similar interventions in unique settings.Methods and analysisThis study protocol outlines a scoping review of the peer-reviewed and grey literature, using established approaches delineated in Arksey and O'Malley’s scoping review framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews Checklist. Search strategies will be developed and refined by a medical librarian in collaboration with the research team. Searches will be conducted in electronic databases (CINAHL, Cochrane, PsychINFO, PubMed, Social Services Abstracts, Web of Science, Google and Google Scholar) and limited to studies published between 1 August 2009 and 1 June 2020. Additionally, hand searches will be conducted in three relevant journals—Implementation Science, Systematic Reviews and BMJ Open. English-language studies and reports meeting inclusion criteria will be screened independently by two reviewers and the final list will be abstracted and charted in duplicate.Ethics and disseminationThis is a review of the literature; ethics approval is not indicated. We will disseminate findings from this study in peer-reviewed journals as well as presentations to relevant stakeholders and conferences.


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