Knowledge Provenance Management System for a Dropwise Additive Manufacturing System for Pharmaceutical Products

2016 ◽  
Vol 55 (36) ◽  
pp. 9676-9686 ◽  
Author(s):  
Elçin Içten ◽  
Girish Joglekar ◽  
Chelsey Wallace ◽  
Kristen Loehr ◽  
Jennifer Sacksteder ◽  
...  
2019 ◽  
Vol 109 (03) ◽  
pp. 179-183
Author(s):  
J. Fischer ◽  
P. Springer ◽  
S. Fulga-Beising ◽  
K. Abu El-Qomsan

Das Fraunhofer IPA forscht an Workflows und Methoden für die Herstellung personalisierter Produkte von der Erfassung persönlicher Daten über die Analyse und Modellierung bis hin zur flexiblen, automatisierten Fertigung der Produkte. Der Beitrag beschreibt einen beispielhaften Anwendungsfall: die Herstellung einer personalisierten Brille. Für die nötige Flexibilität in der Fertigung wurde ein vollständig automatisiertes additives Fertigungssystem entwickelt, das im Applikationszentrum Industrie 4.0 des Fraunhofer IPA und des Instituts für Industrielle Fertigung und Fabrikbetrieb IFF der Universität Stuttgart integriert ist.   Fraunhofer IPA examines workflows and methods for the production of personalized products from the acquisition of personal data, analysis and modelling to the flexible, automated production of the products. This paper exemplifies an application using the production of personalized glasses. For this purpose, a fully automated additive manufacturing system was developed to provide the necessary flexibility in manufacturing.


Author(s):  
Filina I.A. ◽  
Ustinova L.P. ◽  
Fomicheva S.I. ◽  
Varenyk G.V.

The Quality Management System is a universal set of tools that helps to achieve maximum efficiency of any enterprise in all aspects. In order for the Quality Management System in the pharmacy to work effectively for the consumer of pharmaceutical goods, it is necessary to periodically conduct research among the clients of the pharmacy organization. The aim of the work was a comprehensive research among consumers of pharmacy products from the standpoint of the Quality Management System. Normative documents regulating pharmaceutical activities, works of domestic and foreign scientists were adopted as the information base. The questionnaire method was used to tackle the assigned tasks. The objects of the research were the visitors of the pharmacy organizations of the Oryol region. As a result of the study, it was found that efficacy, safety and price are of decisive importance for pharmacy visitors when choosing a drug; the majority of consumers pay attention to the shelf life of a drug when purchasing it (83.0%), however, only 47.0% of respondents attach importance to storage conditions; most pharmacy clients don’t know anything about the list of vital and essential drugs, the minimum range, the international nonproprietary name of the drug; the majority of visitors to pharmacy organizations don’t distinguish between the following concepts: falsified, substandard and counterfeit medicines; some respondents found adverse reactions after taking a drug that weren’t specified in the instructions, some consumers when purchasing drugs faced their defective forms. Thus, on the basis of a comprehensive study carried out among consumers of pharmaceutical products, it can be concluded that it is necessary to develop a system of measures that increase the literacy of the population in the field of the quality of medicines.


2016 ◽  
Vol 73 ◽  
pp. 66-75 ◽  
Author(s):  
Donghong Ding ◽  
Chen Shen ◽  
Zengxi Pan ◽  
Dominic Cuiuri ◽  
Huijun Li ◽  
...  

2011 ◽  
Vol 24 (13) ◽  
pp. 1513-1530 ◽  
Author(s):  
Anderson Marinho ◽  
Leonardo Murta ◽  
Cláudia Werner ◽  
Vanessa Braganholo ◽  
Sérgio Manuel Serra da Cruz ◽  
...  

2018 ◽  
Vol 38 (12) ◽  
pp. 2313-2343 ◽  
Author(s):  
Daniel R. Eyers ◽  
Andrew T. Potter ◽  
Jonathan Gosling ◽  
Mohamed M. Naim

Purpose Flexibility is a fundamental performance objective for manufacturing operations, allowing them to respond to changing requirements in uncertain and competitive global markets. Additive manufacturing machines are often described as “flexible,” but there is no detailed understanding of such flexibility in an operations management context. The purpose of this paper is to examine flexibility from a manufacturing systems perspective, demonstrating the different competencies that can be achieved and the factors that can inhibit these in commercial practice. Design/methodology/approach This study extends existing flexibility theory in the context of an industrial additive manufacturing system through an investigation of 12 case studies, covering a range of sectors, product volumes, and technologies. Drawing upon multiple sources, this research takes a manufacturing systems perspective that recognizes the multitude of different resources that, together with individual industrial additive manufacturing machines, contribute to the satisfaction of demand. Findings The results show that the manufacturing system can achieve seven distinct internal flexibility competencies. This ability was shown to enable six out of seven external flexibility capabilities identified in the literature. Through a categorical assessment the extent to which each competency can be achieved is identified, supported by a detailed explanation of the enablers and inhibitors of flexibility for industrial additive manufacturing systems. Originality/value Additive manufacturing is widely expected to make an important contribution to future manufacturing, yet relevant management research is scant and the flexibility term is often ambiguously used. This research contributes the first detailed examination of flexibility for industrial additive manufacturing systems.


2021 ◽  
Vol 27 (3) ◽  
pp. 636-642
Author(s):  
Qin Qin ◽  
Jigang Huang ◽  
Jin Yao ◽  
Wenxiang Gao

Purpose Scanning projection-based stereolithography (SPSL) is a powerful technology for additive manufacturing with high resolution as well as large building area. However, the surface quality of stitching boundary in an SPSL system has been rarely studied, and no positive settlement was proposed to address the poor stitching quality. This paper aims to propose an approach of multi-pass scanning and a compensation algorithm for multi-pass scanning process to address the issue of poor stitching quality in SPSL systems. Design/methodology/approach The process of multi-pass scanning is realized by scanning regions repeatedly, and the regions can be cured simultaneously because of the very short repeat exposure time and very fast scanning. Then, the poor stitching quality caused by the non-simultaneous curing can be eliminated. Also, a compensation algorithm is designed for multi-pass scanning to reduce the stitching errors. The validity of multi-pass scanning is verified by curing depth test, while the performance of multi-pass scanning as well as proposed compensation algorithm is demonstrated by comparing with that of a previous SPSL system. Findings The results lead to a conclusion that multi-pass scanning with its compensation algorithm is an effective approach to improve the stitching quality of an SPSL system. Practical implications This study can provide advice for researchers to achieve the satisfactory surface finish with SPSL technology. Originality/value The authors proposed a process of multi-pass scanning as well as a compensation algorithm for SPSL additive manufacturing (system to improve the stitching quality, which has rarely been studied in previous work.


Procedia CIRP ◽  
2020 ◽  
Vol 93 ◽  
pp. 32-37 ◽  
Author(s):  
Mandaná Moshiri ◽  
Amal Charles ◽  
Ahmed Elkaseer ◽  
Steffen Scholz ◽  
Sankhya Mohanty ◽  
...  

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