The Future of Computer Simulations Designed for Classroom Instruction

2013 ◽  
pp. 341-365 ◽  
Author(s):  
S. Khan
Keyword(s):  
Computer Simulations ◽  
Classroom Instruction ◽  
The Future

scholarly journals Topological descriptions of protein folding

2019 ◽  
Vol 116 (19) ◽  
pp. 9360-9369 ◽  
Author(s):  
Erica Flapan ◽  
Adam He ◽  
Helen Wong
Keyword(s):  
Protein Folding ◽  
Crystal Structures ◽  
Computer Simulations ◽  
Haloacid Dehalogenase ◽  
Topological Description ◽  
The Future ◽  
Experimental Approaches ◽  
Knotted Proteins ◽  
Plos Comput Biol ◽  
Fingerprint Data

How knotted proteins fold has remained controversial since the identification of deeply knotted proteins nearly two decades ago. Both computational and experimental approaches have been used to investigate protein knot formation. Motivated by the computer simulations of Bölinger et al. [Bölinger D, et al. (2010) PLoS Comput Biol 6:e1000731] for the folding of the 61-knotted α-haloacid dehalogenase (DehI) protein, we introduce a topological description of knot folding that could describe pathways for the formation of all currently known protein knot types and predicts knot types that might be identified in the future. We analyze fingerprint data from crystal structures of protein knots as evidence that particular protein knots may fold according to specific pathways from our theory. Our results confirm Taylor’s twisted hairpin theory of knot folding for the 31-knotted proteins and the 41-knotted ketol-acid reductoisomerases and present alternative folding mechanisms for the 41-knotted phytochromes and the 52- and 61-knotted proteins.

scholarly journals Changes in Teachers’ Classroom Instruction as a Result of Training in Computer Technology

2015 ◽  
Vol 2 (2) ◽  
pp. 168
Author(s):  
Egoza Wasserman
Keyword(s):  
Computer Technology ◽  
Teaching Methods ◽  
Classroom Instruction ◽  
Computerized Instruction ◽  
Computer Instruction ◽  
Training Course ◽  
Technology Teachers ◽  
Use Of Technology ◽  
The Future ◽  
Search For Information

<p><em>This article presents a study that was carried out two years after teachers completed a training course in computerized instruction, entitled “Intel Education for the Future”. The purpose of the study was to measure the degree to which the teachers internalized the skills taught in the training course, thereby</em><em>,</em><em> assisting them in integrating the use of the computer in the classroom. For this purpose, certain parameters were chosen: the teacher’s method of working in the classroom, the effect of computer instruction on the students and the difficulties encountered upon integrating the computer in the classroom. The research tools were questionnaires and interviews. The main conclusion of the research was that the teachers successfully internalized the skills needed for the use of technology. Teachers are now using the computer to search for information suitable for worksheets and tests and for e-mailing their colleagues. Most of the teachers noted that the most useful tool for their work is the </em><em>o</em><em>ffice program. The teachers pointed out that the use of computers raises the students’ motivation and improves their understanding of the material. They did not report any special difficulties in integrating the computer into their teaching methods. </em></p>

Conclusion

2020 ◽  
pp. 339-348
Author(s):  
Hans-Jörg Schmid
Keyword(s):  
Computer Simulations ◽  
Cognitive Processes ◽  
Final Section ◽  
Future Research ◽  
Linguistic System ◽  
Wide Range ◽  
The Future ◽  
Future Work ◽  
Distinguishing Features

This chapter concludes the book. The distinguishing features of the EC-Model are highlighted, especially those that set it apart from the functionalist usage-based mainstream. An outlook on future work identifies weaknesses of the model that must be redressed in the future and sketches some avenues for future research, e.g. by means of computer simulations. The final section returns to the questions what and where the linguistic system can be found and defines the linguistic system as a multidimensional dynamic contingency space populated by multidimensionally competing co-semiotic potentialities afforded by the interaction of speakers’ usage activities and social and cognitive processes under the influence of a wide range of forces.

Synthetic Biology

1998 ◽  
pp. 46-53 ◽  
Author(s):  
John Sullins
Keyword(s):  
Synthetic Biology ◽  
Computer Simulations ◽  
Artificial Life ◽  
Science And Technology ◽  
Essential Step ◽  
The Future ◽  
Shed Light

This paper uses the theory of technoscience to shed light on the current criticisms against the emerging science of Artificial Life. We see that the science of Artificial Life is criticized for the synthetic nature of its research and its over reliance on computer simulations which is seen to be contrary to the traditional goals and methods of science. However, if we break down the traditional distinctions between science and technology using the theory of technoscience, then we can begin to see that all science has a synthetic nature and reliance on technology. Artificial Life researchers are not heretical practitioners of some pseudoscience; they are just more open about their reliance on technology to help realize their theories and modeling. Understanding that science and technology are not as disparate as was once thought is an essential step in helping us create a more humane technoscience in the future.

International determination of the total motion of the pole

1961 ◽  
Vol 13 ◽  
pp. 29-41
Author(s):  
Wm. Markowitz
Keyword(s):  
Secular Motion ◽  
The Future

A symposium on the future of the International Latitude Service (I. L. S.) is to be held in Helsinki in July 1960. My report for the symposium consists of two parts. Part I, denoded (Mk I) was published [1] earlier in 1960 under the title “Latitude and Longitude, and the Secular Motion of the Pole”. Part II is the present paper, denoded (Mk II).

Status of the Lick Proper Motion Program

1978 ◽  
Vol 48 ◽  
pp. 387-388
Author(s):  
A. R. Klemola
Keyword(s):  
Proper Motion ◽  
The Future

Second-epoch photographs have now been obtained for nearly 850 of the 1246 fields of the proper motion program with centers at declination -20° and northwards. For the sky at 0° and northward only 130 fields remain to be taken in the next year or two. The 270 southern fields with centers at -5° to -20° remain for the future.

Some Structural Features of Metaphase Chromosomes of Mice and Men

1967 ◽  
Vol 25 ◽  
pp. 190-191
Author(s):  
Godfrey C. Hoskins ◽  
Betty B. Hoskins
Keyword(s):  
Electron Microscopy ◽  
Electron Micrographs ◽  
Structural Features ◽  
Metaphase Chromosomes ◽  
The Future ◽  
Of Mice And Men ◽  
Mouse Cells ◽  
Human And Mouse

Metaphase chromosomes from human and mouse cells in vitro are isolated by micrurgy, fixed, and placed on grids for electron microscopy. Interpretations of electron micrographs by current methods indicate the following structural features.Chromosomal spindle fibrils about 200Å thick form fascicles about 600Å thick, wrapped by dense spiraling fibrils (DSF) less than 100Å thick as they near the kinomere. Such a fascicle joins the future daughter kinomere of each metaphase chromatid with those of adjacent non-homologous chromatids to either side. Thus, four fascicles (SF, 1-4) attach to each metaphase kinomere (K). It is thought that fascicles extend from the kinomere poleward, fray out to let chromosomal fibrils act as traction fibrils against polar fibrils, then regroup to join the adjacent kinomere.

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