Characteristics of prevalence in peripheral arterial disease and correlative risk factors and comorbidities among female natural population in China

VASA ◽  
2010 ◽  
Vol 39 (4) ◽  
pp. 305-311 ◽  
Author(s):  
Wang ◽  
Xu ◽  
Li ◽  
Wei ◽  
Zhao ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Natural Population ◽  
Smoking Habit ◽  
Arterial Disease ◽  
Lipid Disorders ◽  
History Of ◽  
Peripheral Arterial

Background: To investigate the prevalence of peripheral arterial disease (PAD) and correlating risk factors and comorbidities in a natural female population in China, and to study the characteristics of atherosclerotic disease in females. Patients and methods: Natural population from communities in several cities and districts including Beijing, Shanghai, Changsha, Guangdong, Inner Mongolia, and Xinjiang in China were investigated as study subjects through cluster multistage and random sampling. Ankle-brachial index (ABI) was measured among participants in the communities by trained investigators and correlative information and clinical data were collected. PAD was defined as an ABI ≤ 0.9 in either leg. Results: 21 152 eligible participants were included in the survey. The prevalence in males and females was 2.52 % and 3.66 %, the standardized prevalence was 1.84 % and 4.31 % respectively, and the prevalence in females was higher than that in males (p < 0.01). The prevalence in females obviously increased (p < 0.01) with increasing age. More female participants with PAD were over 69 years old compared with those without PAD (18.8 % vs. 10.0 %, p = 0.000) and more frequently have a smoking habit (11.1 % vs. 2.5 %, p = 0.000), lipid disorders (34.8 % vs. 29.2 %, p = 0.047), diabetes mellitus (14.8 % vs. 8.6 %, p = 0.000), coronary heart disease (16.9 % vs. 10.0 %, p = 0.000) and a history of stroke (6.8 % vs. 2.3 %, p = 0.000). Using multiple logistic regression analysis, older age (> 69 years old, OR: 1.60, 95 % CI: 1.11 - 2.29), a smoking habit (OR: 5.98, 95 % CI: 3.88 - 9.21), comorbidities of lipid disorders (OR: 1.45, 95 % CI: 1.10 - 1.91), diabetes mellitus (OR: 1.46, 95 % CI: 1.02 - 2.11), coronary heart disease (OR: 1.50, 95 % CI: 1.02 - 2.19)and a history of stroke (OR: 1.71, 95 % CI: 1.01 - 2.91) were correlated with the prevalence of PAD in females in China. Only 0.8 % of female patients with PAD had been diagnosed previously. Conclusions: The data suggest that the prevalence of PAD in a female natural population in China is higher than that in males. Many conventional risk factors and comorbidities were correlated with the high prevalence of PAD in females. But only very few female patients with PAD were diagnosed. Thus, more measures should be taken to diagnose, prevent and control PAD in females in China.

scholarly journals Faktor Risiko Terjadinya Penyakit Jantung Koroner pada Pasien di Unit Rawat Jalan Rumah Sakit Panti Rapih Yogyakarta

2020 ◽  
Vol 1 (1) ◽  
pp. 21-30
Author(s):  
Deviana Widayanti ◽  
Chatarina Setya Widyastuti
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Family History ◽  
Disease Risk ◽  
Sampling Technique ◽  
Excess Body Weight ◽  
History Of ◽  
Lack Of Exercise

Background: Coronary Heart Disease (CHD) Is a condition when the arteries that supply blood to the heart wall experience hardening and narrowing. It is estimated that 30% of coronary heart disease causes death worldwide. Objective: This study aims to determine the risk factors for CHD in Panti Rapih Hospital. Methods: This descriptive study aims to determine the risk factors for CHD in outpatients at Panti Rapih Hospital. The population is patients who have been diagnosed with coronary heart disease and the sample was taken by 50 respondents with non-random accidental sampling technique. This research take the data use questionnaire and make univariat analysis. Results: Risk factors for CHD are a number of factors that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight42% and lack of exercise 38%. Conclusion: Risk factors for CHD that cannot be changed: family history of 42%, age = 40 years 95% in men and 95% age = 65 years in women. Factors that can be changed are: Smoking 78%, history of hypertension 68%, history of diabetes mellitus 28%, dyslipidemic 90%, excess body weight 42% and lack of exercise 38%.     Keywords: coronary heart disease, risk factors

scholarly journals A study of prevalence of peripheral arterial disease in type 2 diabetes mellitus using ankle-brachial index and its correlation with coronary artery disease and its risk factors

2019 ◽  
Vol 7 (5) ◽  
pp. 1776
Author(s):  
R. K. Sharma ◽  
Pashaura S. Sandhu ◽  
Ajay Chhabra ◽  
Jagbir Singh ◽  
Rajat Kharbanda
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
History Of ◽  
Peripheral Arterial

Background: Peripheral arterial disease (PAD) is one of the macrovascular complications of type 2 diabetes mellitus (T2DM). There is significant difference in the reported prevalence of PAD and its associated risk factors between Indian and Western studies. The purpose of this study was to examine the PAD complicating T2DM, in particular the influence of PAD on the risk of CAD.Methods: Randomly selected 100 T2DM patients presented to Guru Nanak Dev hospital were included. In addition to a detailed history and physical examination, anthropometric parameters like body mass index was measured. CAD in patients was diagnosed by a history of angina, ECG changes, any past history of CAD or any treatment taken for CAD. Ankle brachial index (ABI) was measured. Data was collected systematically and analyzed according to the standard statistical methods.Results: The prevalence of PAD was 15%. CAD was present in 31%. PAD was found to be significantly correlated with age, duration of diabetes, smoking, systolic blood pressure, diastolic blood pressure, prevalence of BMI >25 kg/m2, HbA1c and serum HDL ≤40 mg%. Old age, high HbA1c level, and dyslipidaemia were found to be significant independent predictors of CAD.Conclusions: Using ABI authors found evidence of PAD in 15% patients of T2DM. The prevalence of CAD was higher in patients with PAD. So, there is definite and strong correlation between PAD and CAD. Thus, the early diagnosis of PAD should alert the clinician to a high probability of underlying CAD.

scholarly journals GAMBARAN PROFIL LIPID PADA PASIEN PENYAKIT JANTUNG KORONER

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Desire Sutrisno ◽  
Agnes L. Panda ◽  
Jeffrey Ongkowijaya
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Uric Acid ◽  
Heart Disease ◽  
Disease Risk ◽  
Smoking History ◽  
Statin Group ◽  
History Of ◽  
Chd Risk Factors

Abstract: Coronary Heart Disease is a heart disease caused by the narrowing of the coronary arteries, which then disturbs the flow of blood to the myocardium. The result of SKRT done by the Health Department Republic of Indonesia showed that deaths due to CHD kept increasing throughout the years, and this had made CHD as the first most common cause of death. This study aimed to find out about the overview of lipid profile in coronary heart disease patients who had consumed statin and who had not. This was a descriptive method, based on the secondary data that were attained directly from patients in CVBC and Irina F Cardiology Department Prof. Dr. R.D. Kandou Hospital. The population in this study were patients with coronary heart disease recorded in medical records inn December 2014 and met the inclusion criteria. The results showed that male CHD patients who consumed statin were 64.7% and non-statin 75.0%; the 36-45 age group and >55 were most commonly found in statins group (35.3%), and age of 36-45 (33.3%) in non-statin group. Smoking history in statin group and non-statin were 52.9% and 62.5%; history of hypertension in statin group and non-statin were 76.5% and 62.5%; history of diabetes mellitus in statin group and non-statin group are 11.8% and 33.3%; familial history of heart disease in statin group and non-statin group were 70.6% and 54.2%; the increase total cholesterol in statin group and non-statin group were 52.9% and 54.2%; the increase of triglycerides in statin group and non-statin groups were 0% and 8,3%; the increase in LDL cholesterol in statin group and non-statin group were 29.4% and 25.0%; the decrease of HDL in statin group and non-statin group were 0% and 25.0%; suffered dyslipidemia in statin group and non-statin are 52.9% and 62.5%, high non-HDL level in statin group and non-statin group were 52.9% and 58.3%; history of uric acid in statin group and non-statin group were 64.7% and 62.5%; type of CHD most commonly found in statin group ATS wre 70.6% and non-statin group NSTEMI 45.8%. Based on the results of this study, the CHD risk factors such as smoking, hypertension, family history of heart disease, dyslipidemia, non-HDL levels, uric acid affected the incidence of CHD more than the diabetes mellitus risk factor.Keywords: coronary heart disease, risk factors, lipid profileAbstrak:Penyakit jantung koroner adalah penyakit jantung yang disebabkan oleh adanya penyempitan pada arteri koronaria, sehingga aliran darah ke otot jantung menjadi terganggu. Hasil survei kesehatan rumah tangga (SKRT) departemen kesehatan Republik Indonesia menunjukkan bahwa dari tahun ke tahun kematian yang disebabkan Penyakit Jantung Koroner makin meningkat dan saat ini menduduki urutan pertama. Penelitian ini bertujuan untuk mengetahui gambaran profil lipid pada pasien penyakit jantung koroner yang telah menggunakan obat statin dan belum menggunakan obat statin. Metode yang digunakan bersifat deskriptif berdasarkan data sekunder yang didapatkan secara langsung pada pasien yang berada di CVBC dan irina F Jantung RSUP Prof. Dr. R.D.Kandou. Populasi pada penelitian ini yaitu penderita Penyakit Jantung Koroner yang tercatat di rekam medik pada 420Sutrisno, Panda, Ongkowijaya: Gambaran profil lipid...bulan Desember 2014 dan memenuhi kriteria inklusi. Penelitian ini menunjukan bahwa pasien PJK berjenis kelamin laki-laki pengguna statin sebesar 64,7% dan non-statin 75,0%. Pada kelompok statin terbanyak umur 36-45 dan 56 ke-atas serta non-statin pada umur 36-45. Riwayat merokok pada pengguna statin dan non-statin sebesar 52,9% dan 62,5%. Riwayat hipertensi pada pengguna statin dan non-statin sebesar 76,5% dan 62,5%. Pasien PJK yang memiliki riwayat diabetes mellitus pada pengguna statin dan non-statin sebesar 11,8% dan 33,3%, yang memiliki riwayat penyakit jantung dalam keluarga pada pengguna statin dan non statin sebesar 70,6% dan 54,2%, peningkatan kolesterol total pada pengguna statin dan non-statin sebesar 52,9% dan 54,2%, peningkatan trigliserida pada pengguna statin dan non-statin sebesar 0% dan 8,3%, peningkatan kolesterol LDL pada pengguna statin dan non-statin sebesar 29,4% dan 25,0%, penurunan HDL pada pengguna statin dan non-statin sebesar 0% dan 25,0%, yang menderita dislipidemia pada pengguna statin dan non-statin sebesar52,9% dan 62,5%, kadar non-HDL yang tinggi pada pengguna statin dan non-statin sebesar 52,9% dan 58,3%, riwayat asam urat pada pengguna statin dan non-statin sebesar 64,7% dan 62,5%. Jenis PJK terbanyak pada pengguna statin ATS sebesar 70,6% dan non-statin NSTEMI sebesar 45,8%. Kesimpulan dalam penelitian ini yaitu faktor resiko seperti merokok, hipertensi, riwayat penyakit jantung dalam keluarga, dislipidemia, kadar non-HDL, asam urat lebih mempengaruhi terjadinya PJK dibandingkan dengan faktor resiko diabetes melitus.Kata kunci: penyakit jantung koroner, faktor risiko, profil lipid

scholarly journals Lack of association between peroxisome proliferator-activated receptor-gamma-2 gene variants and the occurrence of coronary heart disease in patients with diabetes mellitus

2002 ◽  
pp. 545-551 ◽  
Author(s):  
M Bluher ◽  
T Klemm ◽  
T Gerike ◽  
H Krankenberg ◽  
G Schuler ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Multiple Logistic Regression Analysis ◽  
Peroxisome Proliferator ◽  
Haemoglobin A1c ◽  
Peroxisome Proliferator Activated Receptor ◽  
Patients With Diabetes ◽  
Reduced Risk

OBJECTIVE: Recent evidence indicates that peroxisome proliferator-activated receptor-gamma (PPARgamma) is expressed at high levels in foam cells of atherosclerotic lesions, that PPARgamma agonists may directly modulate vessel wall function and that mutations in the PPARgamma-2 gene are associated with a reduced risk of coronary artery disease. METHODS: We investigated whether known variants in the PPARgamma-2 gene are associated with the occurrence of coronary heart disease (CHD) in 365 patients with type 2 diabetes, prospectively characterised for the presence or absence of CHD. The Pro115Gln, Pro12Ala, Pro467Leu, Val290Met mutations and two polymorphisms C478T and C161T of the PPARgamma-2 gene were examined using PCR, denaturing gradient gel electrophoresis and direct sequencing. RESULTS: The distribution of the Pro12Ala, Ala12Ala, C161T and T161T variants was not significantly different between patients with and without CHD, independent of the gender. The Pro12Ala (P=0.011) and the Ala12Ala (P=0.006) variant were associated with a higher body mass index (BMI) compared with the Pro12Pro genotype. A multiple logistic regression analysis introducing the typical risk factors for CHD (age, sex, hypertension, smoking, BMI >26 kg/m2, elevated low density lipoprotein cholesterol and haemoglobin A1c >7%) identified age >60, male gender, hypertension and a higher BMI, but not the PPARgamma-2 variants, as significant risk factors for CHD in our study groups. CONCLUSION: The PPARgamma-2 genotype was not associated with an increased or reduced risk of the occurrence of CHD and can therefore not be regarded as an independent risk factor for CHD in patients with diabetes mellitus.

Clinical factors and mortality rates for non-traumatic upper extremity amputations

2021 ◽  
pp. 175319342110427
Author(s):  
Yong-Zheng Jonathan Ting ◽  
An-Sen Tan ◽  
Chi-Peng Timothy Lai ◽  
Mala Satku
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Lower Extremity ◽  
Upper Extremity ◽  
Significant Risk ◽  
Arterial Disease ◽  
Mortality Rates ◽  
Level Of Evidence ◽  
Peripheral Arterial ◽  
Extremity Amputation

Non-traumatic upper extremity amputations are an increasing concern with the rising prevalence of diabetes mellitus. To ascertain the risk factors and mortality rates for these amputations, the demographic information, amputation history, comorbidities and clinical outcomes of 140 patients who underwent non-traumatic upper extremity amputations between 1 January 2004 and 31 October 2017 were studied. Correlations were assessed using Cochran-Armitage chi-squared tests, odds ratios and multivariate binomial logistic regression as appropriate. Diabetes mellitus, coronary artery disease, end-stage renal failure, peripheral arterial disease and prior lower extremity amputation were significant risk factors for multiple upper extremity amputations. One-year, 2-year and 5-year mortality rates were 12%, 15% and 38%, respectively, following first upper extremity amputation. The risk factors for upper extremity amputations correspond with those for lower extremity amputations, comprising mainly diabetes mellitus and its related comorbidities. The mortality rates for non-traumatic upper extremity amputations highlight their significant burden on patients. Level of evidence: III

scholarly journals Analisis Survival Penyakit Jantung Koroner Berulang

2018 ◽  
Vol 6 (1) ◽  
pp. 43
Author(s):  
Fidya Panorama Damayanti ◽  
Arief Wibowo
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Survival Data ◽  
Recurrent Event ◽  
Observational Research ◽  
Research Approach ◽  
Hypertension Status ◽  
Cox Regression Analysis

Survival analysis is one of data analysis the result showing certain times had happened. Cox regression analysis is one of the most powerful and commonly used for analyzing survival data since the result of this method showing nearly similar result to parametric model. This study aim is to determine case of recurrent Coronary Heart Disease risk factors, and to know how many survival in day of recurrent Coronary Heart Disease based on the risk factors at RS Islam Surabaya in 2015 – 2016. Measurement in research subjects was conducted in the medical record. This research using observational research approach. Subjects were 63 Coronary Heart Disease inpatients in RS Islam Surabaya. Measurement was conducted to obtain information of examined variables. Independent variables were data sensor status, survival time (measured in day), sex, age, hypertension, hyperlipidemia, and diabetes mellitus. This analysis showing the occurrence time average of recurrent CHDs in Coronary Heart Disease patients in general is 614 days. Rate of reccurence had similar risks for all age groups, gender, hypertension, hyperlipidemia, and diabetes mellitus. CHD patients with hypertension status have risk of 9.291 times greater than no hypertension status. This research can be used by RS Islam Surabaya to gave Communication, Information, and Education to the patient and their relatives especially for patient with hypertension status to have continuous check-up in order not to get another recurrent event of CHD in the near future.

scholarly journals Prevalence of peripheral arterial disease and associated factors in people with type 2 diabetes

2021 ◽  
Vol 34 ◽  
Author(s):  
Pedro José da Silva Filho ◽  
Elaine Cristina Martinez Teodoro ◽  
Elaine Cristina Alves Pereira ◽  
Vania Cristina dos Reis Miranda
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Physical Inactivity ◽  
Associated Factors ◽  
Family Health ◽  
Arterial Disease ◽  
The Family ◽  
Peripheral Arterial

Abstract Introduction: The high rate of diabetes mellitus index (DM), along with the increase in cardiovascular compromise that DM favors, and the scarcity of epidemiological data regarding the prevalence of peripheral arterial disease (PAD) in this population, make it important to study risk factors associated with the development of PAD in the population with type 2 diabetes mellitus (DM2). Objective: To estimate the prevalence of PAD together with the associated factors in a sample of patients with DM2, treated in the Family Health Strategies (FHS) program, in the municipality of Pindamonhangaba, SP. Methods: Quantitative research in a cross-sectional study of 38 individuals who were diagnosed with DM2, between 40 and 77 years old, selected by convenience sampling and treated in the family health program in two different districts of the municipality. The method consisted of the evaluation of personal and anthropometric data, anamnesis and physical examination including the ankle-brachial index (ABI). Results: PAD was present in 21.1% (95%CI: 16.9 to 25.8) of the investigated population. Risk factors observed were age range of 51 to 69 years (75%), overweight (50%), systemic arterial hypertension (SAH) (100%), smoking (62.5%) and physical inactivity (87.5%). Conclusion: The prevalence of PAD was more than a fifth of those diagnosed with DM2, and the most prevalent associated risk factors were SAH, physical inactivity, smoking and overweight with and without PAD.

Sign in / Sign up

Export Citation Format

Share Document