scholarly journals Hydropower Flushing Events Cause Severe Loss of Macrozoobenthos in Alpine Streams

2019 ◽  
Vol 55 (12) ◽  
pp. 10056-10081 ◽  
Author(s):  
C. Gabbud ◽  
M. Bakker ◽  
M. Clémençon ◽  
S. N. Lane
Keyword(s):  
Severe Loss ◽  
Alpine Streams

Retrieval of fractured Endodontic Instrument under dental operating microscope using ultrasonic tips : A Case Report

2020 ◽  
Vol 11 (3) ◽  
pp. 3316-3321
Author(s):  
Samrudhi Khatod ◽  
Anuja Ikhar ◽  
Pradnya Nikhade ◽  
Manoj chandak
Keyword(s):  
Case Report ◽  
Root Canal ◽  
Fracture Resistance ◽  
Root Canal Treatment ◽  
Operating Microscope ◽  
Severe Loss ◽  
Mechanical Procedure ◽  
Root Dentin ◽  
Fracture Level

A Patient came with the complaint of pain in the lower right back region of the jaw. Root canal treatment was planned. While preparing for the bio-mechanical procedure, the Hand pro taper fractured in the apical third. Iatrogenic occurred as a result of the fracture of the endodontic instrument. Retrieval of the fractured instrument was planned to complete the cleaning and shaping of the canal. The removal of the fractured instrument was planned to be done under the Dental Operating Microscope. The use of an operating microscope enhanced the illumination and the magnification of the instrument. This illumination and magnification helped in the precision of removal. The ultrasonic tip enabled to reach of the fractured instrument in the canal and loosen the dentin around the fractured instrument. It allowed easy retrieval of the fractured instrument. During the retrieval procedure, the fractured instrument was bypassed before the use of the ultrasonic tip. After the removal of the fractured instrument, cleaning and shaping were completed, followed by obturation, definitive restoration, and prosthesis. As the removal of the fractured instrument enabled complete cleaning and shaping, it improved the prognosis of the case. When the endodontic instrument gets fractured, it should be analyzed over the radiograph to assess the fracture level, the anatomy of the root canal, size of the fractured instrument, check accessibility, stage of fracture, etc. If all the above criteria are met with the removal of the instrument only then, replacement should be tried. Otherwise, it may lead to a severe loss of root dentin, decreasing fracture resistance of the root.

Application of Monoterpenoids and their Derivatives for Treatment of Neurodegenerative Disorders

2019 ◽  
Vol 25 (39) ◽  
pp. 5327-5346 ◽  
Author(s):  
Konstantin P. Volcho ◽  
Sergey S. Laev ◽  
Ghulam Md Ashraf ◽  
Gjumrakch Aliev ◽  
Nariman F. Salakhutdinov
Keyword(s):  
Alzheimer’S Disease ◽  
Clinical Trials ◽  
Huntington's Disease ◽  
Neurodegenerative Disorders ◽  
Heterogeneous Group ◽  
Neuroprotective Activity ◽  
Severe Loss ◽  
Neurotrophic Activity ◽  
Full Proof ◽  
Effective Treatments

Neurodegenerative disorders (NDDs) like Alzheimer's disease, Parkinson’s disease and Huntington’s disease are a heterogeneous group of disorders with the progressive and severe loss of neurons. There are no full proof cures for these diseases, and only medicines are available that can alleviate some of the symptoms. Developing effective treatments for the NDDs is a difficult but necessary task. Hence, the investigation of monoterpenoids which modulate targets applicable to many NDDs is highly relevant. Many monoterpenoids have demonstrated promising neuroprotective activity mediated by various systems. It can form the basis for elaboration of agents which will be useful both for the alleviation of symptoms of NDDs and for the treatment of diseases progression and also for prevention of neurodegeneration. The further developments including detections of monoterpenoids and their derivatives with high neuroprotective or neurotrophic activity as well as the results of qualified clinical trials are needed to draw solid conclusions regarding the efficacy of these agents.

Regimes of primary production and their drivers in Alpine streams

2021 ◽  
Author(s):  
Marta Boix Canadell ◽  
Lluís Gómez‐Gener ◽  
Amber J. Ulseth ◽  
Mélanie Clémençon ◽  
Stuart N. Lane ◽  
...  
Keyword(s):  
Primary Production ◽  
Alpine Streams

Longitudinal and seasonal pattern of insect emergence in alpine streams

2005 ◽  
Vol 39 (1) ◽  
pp. 67-78 ◽  
Author(s):  
Leopold Füreder ◽  
Manfred Wallinger ◽  
Rainer Burger
Keyword(s):  
Seasonal Pattern ◽  
Insect Emergence ◽  
Alpine Streams

scholarly journals Predicting Macroinvertebrate Responses to Water Abstraction in Alpine Streams

Water ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2121
Author(s):  
Gabriele Consoli ◽  
Fabio Lepori ◽  
Christopher T. Robinson ◽  
Andreas Bruder
Keyword(s):  
Habitat Model ◽  
Feeding Guilds ◽  
Physical Habitat ◽  
Macroinvertebrate Communities ◽  
Indirect Measure ◽  
Water Abstraction ◽  
Habitat Template ◽  
Hydropower Potential ◽  
Hydraulic Conditions ◽  
Alpine Streams

Exploitation of hydropower potential in alpine areas undermines the ecological integrity of rivers. Damming and water abstraction substantially alter the physical habitat template of rivers, with strong repercussions on aquatic communities and their resources. Tools are needed to predict and manage the consequences of these alterations on the structure and functioning of macroinvertebrate communities and resource availability in alpine streams. We developed habitat preference models for taxa, functional feeding guilds, and organic resources to quantify the effects of discharge alteration on macroinvertebrate communities in two alpine streams. Our physical habitat model related an indirect measure of bottom hydraulic forces (FST hemispheres) to the distribution of macroinvertebrate taxa and their resources. We observed that flow-dependent habitat availability for macroinvertebrate communities generally decreased with increasing water abstraction. We were able to relate these changes to near-bed hydraulic conditions. Our results suggest, however, the existence of upper discharge thresholds delimiting optimal habitat conditions for taxa. In contrast, we found weak effects of near-bed hydraulic conditions on resource distribution. Overall, our findings contribute towards predicting the impacts of water abstraction on macroinvertebrate communities in small alpine streams and the benefits of baseflow restoration.

scholarly journals A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Sonal Nagarkar-Jaiswal ◽  
Pei-Tseng Lee ◽  
Megan E Campbell ◽  
Kuchuan Chen ◽  
Stephanie Anguiano-Zarate ◽  
...  
Keyword(s):  
Null Mutant ◽  
Loss Of Function ◽  
Severe Loss ◽  
New Strategy ◽  
Mutant Phenotypes

Here, we document a collection of ∼7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstrate reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates.

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