Still young at heart: Negative age-related information motivates distancing from same-aged people.

2012 ◽  
Vol 27 (1) ◽  
pp. 173-180 ◽  
Author(s):  
David Weiss ◽  
Alexandra M. Freund
2021 ◽  
Vol 8 ◽  
Author(s):  
Lidia Cobos-Palacios ◽  
Jaime Sanz-Cánovas ◽  
Mónica Muñoz-Ubeda ◽  
María Dolores Lopez-Carmona ◽  
Luis Miguel Perez-Belmonte ◽  
...  

Atherosclerotic cardiovascular diseases (ASCVD) are the leading cause of death worldwide. High levels of total cholesterol—and of low-density lipoprotein cholesterol in particular—are one of the main risk factors associated with ASCVD. Statins are first-line treatment for hypercholesterolemia and have been proven to reduce major vascular events in adults with and without underlying ASCVD. Findings in the literature show that statins reduce coronary and cerebrovascular morbidity and mortality in middle-aged people, but their benefits in older adults are not as well-established, especially in primary prevention. Furthermore, many particularities must be considered regarding their use in old subjects, such as age-related changes in pharmacokinetics and pharmacodynamics, comorbidities, polypharmacy, and frailty, which decrease the safety and efficacy of statins in this population. Myopathy and a possible higher risk of falling along with cognitive decline are classic concerns for physicians when considering statin use in the very old. Additionally, some studies suggest that the relative risk for coronary events and cardiovascular mortality associated with high levels of cholesterol decreases after age 70, making the role of statins unclear. On the other hand, ASCVD are one of the most important causes of disability in old subjects, so cardiovascular prevention is of particular interest in this population in order to preserve functional status. This review aims to gather the current available evidence on the efficacy and safety of statin use in very old patients in both primary and secondary prevention.


Author(s):  
Jean E. Fox

Advanced Traveler Information Systems (ATIS) are in-vehicle computer systems that provide travel-related information (e.g., navigation assistance) to automobile drivers. ATIS has great potential to help drivers save time and money by leading them to their destination efficiently. However, there are great concerns that ATIS may interfere with driving performance. This study looked at the effects of ATIS use and the driver's age on driving performance in a high-fidelity driving simulator. The results indicate that ATIS use led to degraded driving performance in several measures. However, in some cases, the effects depended on age. Older drivers tended to be more cautious, while younger drivers tended to be more careless. These results suggest that ATIS systems and training materials may need to address the age-related differences in ATIS use and driving performance.


2020 ◽  
Author(s):  
Ryan C Moore ◽  
Angela Y Lee ◽  
Jeffrey T Hancock ◽  
Meghan C Halley ◽  
Eleni Linos

BACKGROUND As COVID-19 poses different levels of threat to people of different ages, health communication regarding prevention measures such as social distancing and isolation may be strengthened by understanding the unique experiences of various age groups. OBJECTIVE The aim of this study was to examine how people of different ages (1) experienced the impact of the COVID-19 pandemic and (2) their respective rates and reasons for compliance or noncompliance with social distancing and isolation health guidance. METHODS We fielded a survey on social media early in the pandemic to examine the emotional impact of COVID-19 and individuals’ rates and reasons for noncompliance with public health guidance, using computational and content analytic methods of linguistic analysis. RESULTS A total of 17,287 participants were surveyed. The majority (n=13,183, 76.3%) were from the United States. Younger (18-31 years), middle-aged (32-44 years and 45-64 years), and older (≥65 years) individuals significantly varied in how they described the impact of COVID-19 on their lives, including their emotional experience, self-focused attention, and topical concerns. Younger individuals were more emotionally negative and self-focused, while middle-aged people were other-focused and concerned with family. The oldest and most at-risk group was most concerned with health-related terms but were lower in anxiety (use of fewer anxiety-related terms) and higher in the use of emotionally positive terms than the other less at-risk age groups. While all groups discussed topics such as acquiring essential supplies, they differentially experienced the impact of school closures and limited social interactions. We also found relatively high rates of noncompliance with COVID-19 prevention measures, such as social distancing and self-isolation, with younger people being more likely to be noncompliant than older people (<i>P</i>&lt;.001). Among the 43.1% (n=7456) of respondents who did not fully comply with health orders, people differed substantially in the reasons they gave for noncompliance. The most common reason for noncompliance was not being able to afford to miss work (n=4273, 57.3%). While work obligations proved challenging for participants across ages, younger people struggled more to find adequate space to self-isolate and manage their mental and physical health; middle-aged people had more concerns regarding childcare; and older people perceived themselves as being able to take sufficient precautions. CONCLUSIONS Analysis of natural language can provide insight into rapidly developing public health challenges like the COVID-19 pandemic, uncovering individual differences in emotional experiences and health-related behaviors. In this case, our analyses revealed significant differences between different age groups in feelings about and responses to public health orders aimed to mitigate the spread of COVID-19. To improve public compliance with health orders as the pandemic continues, health communication strategies could be made more effective by being tailored to these age-related differences.


Author(s):  
Антонина Владимировна Алексеева ◽  
Анатолий Яковлевич Рыжов ◽  
Данила Игоревич Игнатьев

Исследованы антропометрические показатели и параметры состава тела у лиц среднего возраста. Установлено, что некоторые калиперометрические показатели испытывают различие у мужчин и женщин. Калиперометрические показатели величины кожных покровов спины, медиальной и латеральной поверхностей бедер характеризуются тесными положительными корреляциями. Anthropometric indicators and parameters of body composition in middle-aged people were studied. It is established that some caliperometric indicators experience a difference in men and women. Caliperometric indicators of the size of the skin of the back, medial and lateral surfaces of the thighs are characterized by close positive correlations.


2015 ◽  
Vol 37 (4) ◽  
pp. 1513-1526 ◽  
Author(s):  
Lianjun Pan ◽  
Jiehua Ma ◽  
Feng Pan ◽  
Dan Zhao ◽  
Jianping Gao

Background/Aims: Erectile dysfunction (ED) in aged people remains a topic of interest to andrological physicians. Long non-coding RNAs (lncRNAs), which form the largest group of non-coding RNAs, have been shown to regulate various biological processes. The function of lncRNAs in age-related erectile dysfunction (A-ED) pathogenesis remains poorly understood. Methods: This study aims to assess the differential expression profiles of mRNAs and lncRNAs between A-ED and normal control (NC) samples. Using a second-generation lncRNA microarray, we detected a total of 8,744 lncRNAs and 13,585 coding transcripts. Results: We identified 608 up-regulated and 406 down-regulated lncRNAs in A-ED compared with NC samples, by setting a filter of fold-change >2.0. Gene Ontology and pathway analysis revealed that a muscle contraction disorder induced by abnormal ion channels might play a critical role in the pathogenesis of A-ED. Conclusion: Our results show significantly altered expression profiles of lncRNAs and mRNAs between A-ED and NC. This study may provide information for further research on A-ED and may be helpful for finding a new therapeutic target for A-ED.


2013 ◽  
Vol 28 (4) ◽  
pp. 1140-1146 ◽  
Author(s):  
David Weiss ◽  
Kai Sassenberg ◽  
Alexandra M. Freund

2021 ◽  
Author(s):  
Gholam Abbas Roustaei ◽  
Fatemeh Shomali ◽  
Hemmat Gholinia ◽  
Maral Farzin ◽  
Seyed Ahmad Rasoulinejad

Cataract is a multifactorial ocular disease, resulting in turbidity or opacity of the lens of the eyes, which leads to blindness or reduction of visuality. The different environmental, socio-economical, and lifestyle factors indicate as risk factors of age-related cataracts. The aim of this study was the evaluation of daily activity, dietary regimen, residence location and etc., as risk factors of age-related cataracts. In this census, a crosssectional study was performed on 353 patients with age-related cataract underwent surgery, who referred to Rouhani Hospital in Babol, Iran from 2018 to 2019, and 343 healthy individuals. The lifestyle-related information was collected from all individuals via the designed questionnaire. Our results showed that there were significant correlations between the birth/residence in the village (comparing to city, P<0.001), abnormal sleeping time (P<0.001), daily activity (and being outdoor, P<0.001), and use of solid oil (P<0.001) with increasing in age-related cataracts. Furthermore, the use of antioxidant-containing fruits significantly reduces the risk of age-related cataracts. Our results established that lifestyle clearly has a golden impact on age-related cataracts. The reduction in daily activity, normal sleeping time, and more use of antioxidant-containing dietary regimen play a preventive role in age-related cataracts.


2020 ◽  
Vol 2 ◽  
pp. 1-1
Author(s):  
Lina Dönni ◽  
Susanne Bleisch ◽  
Rainer Roth ◽  
Mario Pozza ◽  
Daria Hollenstein ◽  
...  

Abstract. Most of the western countries currently experience a demographic change. It is essential catching this structural change with all its socio-spatial and life-specific dimensions and make it visible in a generally understandable way.The atlas of the aging society 2.0, based on a first version launched in 2017, aims to visualize age-related information in an interactive web application that supports not only the content but also engages the users, is accessible to a broad audience, offers opportunities for different stakeholders and levels of interest, and can accommodate a high range of data as well as future updates.As in the initial version, the atlas of aging society 2.0 operates with a novel concept called the story-network principle which connects briefly introduced visualizations such that a braid of age-related information develops. Like conventional atlases, the dimensions of information are divided into different topic areas. Each topic comprises several stories consisting of multiple information cards. Various connecting lines link the cards together and integrate all of them into an informational network. Storylines connect cards in a directional order such that their information covers a particular aspect of a topic. Related-card lines link cards that have similar content but do not belong to the same story, while recommended-card lines prevent users from dead ends by connecting story ending cards with different story starting cards. The user decides at any time whether he/she wants to follow a storyline through a whole topic aspect or if he/she interrupts the story and navigates into other topics to explore further information.The story-network is visibly displayed on the web application’s landing page and follows the reverse conclusion from Tobler's first law of geography. The similarity in the content of information cards reflects their spatial position in the network. The information cards are displayed as nodes. The appearance of the edges explains the type of connection between the nodes. To immerse oneself in the informational network of the atlas of aging society 2.0, different options are available. It is possible to navigate directly from the story-network view on the landing page to a specific card by a single click on the representative node. To give the user an idea of what information is hidden behind the nodes, the title of the nodes can be displayed in the story network view using an on-touch function. The topic-entry option is ideal for users who search for specific information. Therefore, an interactive and hierarchically organized bubble plot was created. When hovered, the bubble plot first divides into topic-area bubbles. On a second level, these are divided into individual stories, from which the user can choose. A third option is the usage of the coincidence-button, leading the user to a random card.Each card includes a visualization, a descriptive text, and some additional information compromised in the metadata. The visualizations follow a uniform visual language, by using a constant colour concept and an overarching design language. The graphical representations use the D3.js and DC.js JavaScript libraries. One aim of the atlas of aging society 2.0 was to make visualizations more interactive by working with hover- and click-functions and by the implementation of interactive dashboards. The ability to interact with selected visualizations intends to motivate users to explore and display data according to their interests.The atlas of aging society 2.0 is currently optimized for tablets while a desktop version is in progress. In this version, there are many new exciting subject areas and contents, which can be explored. The use of the story-network principle as implemented in this project is also conceivable for other applications due to its linking and ordering properties and its easy scalability.


2022 ◽  
Vol 15 ◽  
Author(s):  
Claudio de’Sperati ◽  
Marco Granato ◽  
Michela Moretti

Perception and action are tightly coupled. However, there is still little recognition of how individual motor constraints impact perception in everyday life. Here we asked whether and how the motor slowing that accompanies aging influences the sense of visual speed. Ninety-four participants aged between 18 and 90 judged the natural speed of video clips reproducing real human or physical motion (SoS, Sense-of-Speed adjustment task). They also performed a finger tapping task and a visual search task, which estimated their motor speed and visuospatial attention speed, respectively. Remarkably, aged people judged videos to be too slow (speed underestimation), as compared to younger people: the Point of Subjective Equality (PSE), which estimated the speed bias in the SoS task, was +4% in young adults (&lt;40), +12% in old adults (40–70) and +16% in elders. On average, PSE increased with age at a rate of 0.2% per year, with perceptual precision, adjustment rate, and completion time progressively worsening. Crucially, low motor speed, but not low attentional speed, turned out to be the key predictor of video speed underestimation. These findings suggest the existence of a counterintuitive compensatory coupling between action and perception in judging dynamic scenes, an effect that becomes particularly germane during aging.


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