scholarly journals Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

2016 ◽  
Vol 115 (5) ◽  
pp. 624-631 ◽  
Author(s):  
Nikhil K Khankari ◽  
◽  
Harvey J Murff ◽  
Chenjie Zeng ◽  
Wanqing Wen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Polyunsaturated Fatty Acids ◽  
Prostate Cancer Risk ◽  
Mendelian Randomisation

scholarly journals A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1647
Author(s):  
Karin Yurko-Mauro ◽  
Mary Van Elswyk ◽  
Lynn Teo
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Polyunsaturated Fatty Acids ◽  
Scoping Review ◽  
Genetic Variants ◽  
Prostate Cancer Risk ◽  
Lymphocytic Leukemia ◽  
Omega 3 ◽  
Long Chain

This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast cancer (n = 2), gastric cancer (n = 1), exocrine pancreatic cancer (n = 1), chronic lymphocytic leukemia (n = 1), prostate cancer (n = 7) and colorectal cancer (n = 6). An additional 13 studies that focused on fish intake or at-risk populations were summarized to increase readers’ understanding of the topic based on this review, DHA and EPA interact with certain genetic variants to decrease breast, colorectal and prostate cancer risk, although data was limited and identified polymorphisms were heterogeneous. The evidence to date demonstrates that omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) may decrease cancer risk by affecting genetic variants of inflammatory pathways, oxidative stress and tumor apoptosis. Collectively, data supports the notion that once a genetic variant is identified, the benefits of a targeted, personalized therapeutic regimen that includes DHA and/or EPA should be considered.

scholarly journals O6-2.5 Alcohol and prostate cancer risk: a mendelian randomisation approach

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A60-A60
Author(s):  
L. Zuccolo ◽  
S. Lewis ◽  
F. Hamdy ◽  
D. Neal ◽  
J. Donovan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Mendelian Randomisation

scholarly journals Circulating Fatty Acids and Prostate Cancer Risk: Individual Participant Meta-Analysis of Prospective Studies

2014 ◽  
Vol 106 (9) ◽  
Author(s):  
Francesca L. Crowe ◽  
Paul N. Appleby ◽  
Ruth C. Travis ◽  
Matt Barnett ◽  
Theodore M. Brasky ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Prostate Cancer Risk ◽  
Individual Participant

scholarly journals Circulating fatty acids and prostate cancer risk in a nested case‐control study: The Multiethnic Cohort

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Song‐Yi Park ◽  
Lynne R. Wilkens ◽  
Susanne M. Henning ◽  
Brian E. Henderson ◽  
Laurence N. Kolonel
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Case Control Study ◽  
Prostate Cancer Risk ◽  
Case Control ◽  
Multiethnic Cohort ◽  
Nested Case Control ◽  
Control Study

scholarly journals Effect Modification by Time Since Blood Draw on the Association Between Circulating Fatty Acids and Prostate Cancer Risk

2016 ◽  
Vol 108 (11) ◽  
pp. djw141 ◽  
Author(s):  
Meng Yang ◽  
Howard D. Sesso ◽  
Graham A. Colditz ◽  
Jing Ma ◽  
Meir J. Stampfer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Effect Modification ◽  
Blood Draw

scholarly journals Plasma Phospholipid Fatty Acids and Prostate Cancer Risk in the SELECT Trial

2013 ◽  
Vol 105 (15) ◽  
pp. 1132-1141 ◽  
Author(s):  
Theodore M. Brasky ◽  
Amy K. Darke ◽  
Xiaoling Song ◽  
Catherine M. Tangen ◽  
Phyllis J. Goodman ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Plasma Phospholipid ◽  
Phospholipid Fatty Acids ◽  
Select Trial
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