scholarly journals The Gibco™ CTS™ Rotea™ system story—a case study of industry-academia collaboration

Gene Therapy ◽  
2021 ◽  
Author(s):  
Anqi Li ◽  
David James ◽  
Rebecca Lim
Keyword(s):  
Value Chain ◽  
Academic Research ◽  
Manufacturing Cell ◽  
The World ◽  
Thermo Fisher Scientific ◽  
Origin Story ◽  
International Sales ◽  
Processing Device ◽  
Fisher Scientific

AbstractThe Gibco™ CTS™ Rotea™ Counterflow Centrifugation System is an automated cell processing device developed for manufacturing cell therapy products. The developer (Scinogy Pty Ltd) collaborated with Thermo Fisher Scientific to successfully launch the product in late 2020, completing product development from concept to international sales in <3years. This article describes the origin story of the Rotea system and how a chance meeting between a co-inventor of the Rotea system and an academic cell biologist took the invention from a garage workshop to the world stage. We describe the contribution of academic research to the innovation value chain and importance of academic institutions being industry-ready to support such collaborations.

scholarly journals Differential Expression of Inflammation-Related Genes in Down Syndrome Patients with or without Periodontal Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
M. Baus-Domínguez ◽  
R. Gómez-Díaz ◽  
D. Torres-Lagares ◽  
J. R. Corcuera-Flores ◽  
J. C. Ruiz-Villandiego ◽  
...  
Keyword(s):  
Gene Expression ◽  
Down Syndrome ◽  
Periodontal Disease ◽  
Differential Expression ◽  
Clinical Feature ◽  
Related Gene ◽  
Thermo Fisher Scientific ◽  
Oral Inflammation ◽  
Fisher Scientific

Aim. Aware that Down Syndrome patients present among their clinical characteristics impaired immunity, the aim of this study is to identify the statistically significant differences in inflammation-related gene expression by comparing Down Syndrome patients with Periodontal Disease (DS+PD+) with Down Syndrome patients without Periodontal Disease (DS+PD-), and their relationship with periodontitis as a chronic oral inflammatory clinical feature. Materials and Methods. Case study and controls on eleven Down Syndrome patients (DS+PD+ vs. DS+PD-). RNA was extracted from peripheral blood using a Qiagen PAXgene Blood miRNA Kit when performing an oral examination. A search for candidate genes (92 selected) was undertaken on the total genes obtained using a Scientific GeneChip® Scanner 3000 (Thermo Fisher Scientific) and Clariom S solutions for human, mouse, and rat chips, with more than 20,000 genes annotated for measuring expression levels. Results. Of the 92 inflammation-related genes taken initially, four genes showed a differential expression across both groups with a p value of <0.05 from the data obtained using RNA processing of the patient sample. Said genes were TNFSF13B (p=0.0448), ITGB2 (p=0.0033), ANXA3 (p=0.0479), and ANXA5 (p=0.016). Conclusions. There are differences in inflammation-related gene expression in Down Syndrome patients when comparing patients who present a state of chronic oral inflammation with patients with negative rates of periodontal disease.

3D technology in fashion: from concept to consumer

2018 ◽  
Vol 22 (2) ◽  
pp. 240-251 ◽  
Author(s):  
Veronica Arribas ◽  
José A. Alfaro
Keyword(s):  
Value Chain ◽  
Digital Technology ◽  
Academic Research ◽  
Digital Culture ◽  
Fashion Industry ◽  
3D Technology ◽  
Content Type ◽  
Haute Couture ◽  
3D Software

Purpose The purpose of this paper is to show how 3D digital technology can bring value to the fashion industry by analysing the specific benefits it offers along the value chain. Additionally, the authors show some of the challenges ahead identified for both software and fashion firms. Design/methodology/approach The authors present by means of a case study the experience of an haute couture designer who used 3D digital technology – in collaboration with a recognised 3D software company – for developing his first luxury footwear collection. Findings The enhancement of creativity and a better communication with suppliers are just some of the benefits identified in the case study from the use of 3D digital technology. In addition, challenges such as the development of a digital culture or the need for technology simplification are drawn from the case. Practical implications Apart from the benefits and challenges drawn from the case study, which can be useful to practitioners in this industry, the authors also identify the collaboration through which the experience took place as an interesting practice to implement as a previous step of a digital transformation strategy. Originality/value Despite the growing interest the fashion industry is showing in the use of new digital technologies, academic research on this topic is still scarce. Therefore, the case study presented in this paper adds value to the literature showing how 3D technology can help fashion from concept to consumer.

Status and prospects for the libraries of academic research institutes (as the case study of SB RAS Novosibirsk Scientific Center libraries). Part 1

2021 ◽  
pp. 43-57
Author(s):  
O. L. Lavrik ◽  
I. G. Yudina ◽  
T. A. Kalyuzhnaya
Keyword(s):  
Academic Libraries ◽  
Information Source ◽  
Academic Research ◽  
Data Repository ◽  
Survey Questionnaire ◽  
Scientific Center ◽  
Academic Administration ◽  
Research Institutes ◽  
The World

The role and tasks of academic libraries are changing due to external factors, and among them is the atrophy of their function as the only information source. The authors analyze the survey of the Novosibirsk Scientific Center’s libraries related to the relevant services provided by academic libraries. The study goal is to determine the balance of traditional and innovated tasks being accomplished by the libraries. The idea of the survey was conceived in 2019 before the pandemic. In Part One, the authors describe the methods and methodology of their study. The key method is the survey questionnaire. The findings are analyzed and the conclusions are presented: to solve new problems (like establishing and maintaining the systems for monitoring researchers’ publication activity, maintenance of institutional data repository, preparation of reviews and analytical surveys, advocating institutes through social media, users support on copyright and plagiarism, consulting on grant selection and application), academic administration bring the expertise of librarians, or establish new structures; however, the librarians are insufficiently engaged in solving the new tasks of science support. The authors suggest that their findings reflect the activities of academic libraries, however after the pandemic, the situation may change with the world.

Excavating Repositories: Academic Research Projects Using Archaeological Collections

2019 ◽  
Vol 7 (3) ◽  
pp. 247-257 ◽  
Author(s):  
Paola A. Schiappacasse
Keyword(s):  
Puerto Rico ◽  
Academic Research ◽  
Direct Result ◽  
Government Agencies ◽  
Research Projects ◽  
World Archaeological ◽  
Archaeological Collections ◽  
The World ◽  
Beneficial Approach

ABSTRACTAround the world, archaeological collections are curated in museums, universities, foundations, government agencies, and other organizations. Some are carefully documented and readily accessible, while others are languishing in substandard conditions as a direct result of the curation crisis. This article highlights the value of collection-based research. It encourages the mutually beneficial approach of training students in both collection preservation and collection-based research and demonstrates other ways to obtain data for research projects, aside from excavation. Using my collections-based research carried out in Puerto Rico and the continental United States as a case study, I draw attention to the valuable information that can be derived from acquisition and accession documents and offer ways to incorporate new datasets. This allows for more accurate narratives of collections’ historiographies.

scholarly journals Patent Data for Comparative Study: Case study of Top Aspirants in Bioinformatics Industry

2018 ◽  
Vol 6 (1) ◽  
pp. 33-39
Author(s):  
Neha Mago ◽  
Nishad Deshpande
Keyword(s):  
Comparative Study ◽  
Research Areas ◽  
Genomics And Proteomics ◽  
Major Player ◽  
Innovation And Technology ◽  
Thermo Fisher Scientific ◽  
Study Case ◽  
The Comparative Study ◽  
Fisher Scientific

Innovation and technology are considered as a subject of success and achievement to the firm. The comparative study represents an essential procedure to identify the innovation and technological capabilities of major players involved in the bioinformatics related inventions. The aim of the research is to map out the top firms and identify their strategically important technologies. In view of this, the comparative analysis of major firms in bioinformatics industry is carried out using patent information. Herein the top three assignees are considered and based on this further analysis is performed. The top companies’ trend suggests that Thermo Fisher Scientific Inc. is the major player in bioinformatics research. Thus, we have tried to develop an overview on their patenting trend and important concerned areas of research. Also, our results indicate that the application of computational tools is being utilized for most of the research areas like the study of genomics and proteomics, sequence categorization and their structural prediction.

scholarly journals An assessment of the expansion strategy followed by Avianca Airlines: Period 2008-2012

2017 ◽  
Vol 7 (1) ◽  
pp. 80
Author(s):  
Mauricio Emboaba Moreira
Keyword(s):  
Analytical Model ◽  
Academic Research ◽  
Analytical Framework ◽  
Expansion Process ◽  
Expansion Strategy ◽  
Mother Country ◽  
Wide Range ◽  
The World ◽  
Expansion Strategies

Purpose: This article aims to apply to the case of Avianca Airlines the Analytical Model for the Assessment of Airline Expansion Strategies developed by Moreira (2014) in order to explain the rationale of the expansion strategy followed by this airline and indicate other possible expansion strategies. Design/methodology/approach: This article is a case study in the sense that it aims to arrive to broad generalizations based on the collected evidences, focusing on one of the most traditional airlines in the world. This article is a positivist case study, based in the positivist understanding; because it is supported by objective facts of the situation which are informed by the researcher’s interpretive understanding according to it is recommended for this type of study.Findings: The application of the Analytical Model for the Assessment of Airline Expansion Strategies above referred was successful, considering that the model was able to explain a wide range of complex aspects of the Avianca’s development. Thus, being one of the oldest airlines in continued operation in the world, the expansion process of this airline is connected to many political, sociological and economic facets - ie., its general environment - of its mother country, Colombia. The analytical model offered the opportunity to explore these issues in a detailed manner, adding a broader comprehension of this airline that goes beyond its operating and economic analysis.Originality/value: They reside on the fact that this is the first time that this analytical model is applied to study extensively an actual situation. Besides, airlines in Latin America have not been widely covered by the academia and this is an opportunity to begin to fill this gap. Furthermore, the referred analytical model is applicable to organizations or firms that operate in other industries if the proper adjustments are made.Implications: The implications for the academic research are to understand that the reasons for the success or failure of an airline in an expansion process may be explained by the suitability between the expansion strategy followed by this airline, its business model, its operating environment and its general environment. Moreover, this article demonstrates that the analysis of the suitability of the expansion strategy followed by a specific airline may be made in the light of a solidly founded analytical framework.

Culture and the plasticity of perception

2020 ◽  
Vol 43 ◽  
Author(s):  
Michael Lifshitz ◽  
T. M. Luhrmann
Keyword(s):  
Cultural Context ◽  
Sensory Experience ◽  
Cultural Learning ◽  
The World

Abstract Culture shapes our basic sensory experience of the world. This is particularly striking in the study of religion and psychosis, where we and others have shown that cultural context determines both the structure and content of hallucination-like events. The cultural shaping of hallucinations may provide a rich case-study for linking cultural learning with emerging prediction-based models of perception.

HIPEREMESIS GRAVIDARUM PADA IBU HAMIL DI KLINIK BIDAN SUPRIYATI SRIBIT BERBAH SLEMAN

2019 ◽  
Vol 14 (1) ◽  
pp. 51
Author(s):  
Pramukti Dian Setianingrum ◽  
Farah Irmania Tsani
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Unwanted Pregnancy ◽  
The Body ◽  
Nausea And Vomiting ◽  
Daily Activities ◽  
World Health ◽  
The World

Backgroud: The World Health Organization (WHO) explained that the number of Hyperemesis Gravidarum cases reached 12.5% of the total number of pregnancies in the world and the results of the Demographic Survey conducted in 2007, stated that 26% of women with live births experienced complications. The results of the observations conducted at the Midwife Supriyati Clinic found that pregnant women with hyperemesis gravidarum, with a comparison of 10 pregnant women who examined their contents there were about 4 pregnant women who complained of excessive nausea and vomiting. Objective: to determine the hyperemesis Gravidarum of pregnant mother in clinic. Methods: This study used Qualitative research methods by using a case study approach (Case Study.) Result: The description of excessive nausea of vomiting in women with Hipermemsis Gravidarum is continuous nausea and vomiting more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the body weight decreases and interferes with daily activities days The factors that influence the occurrence of Hyperemesis Gravidarum are Hormonal, Diet, Unwanted Pregnancy, and psychology, primigravida does not affect the occurrence of Hyperemesis Gravidarum. Conclusion: Mothers who experience Hyperemesis Gravidarum feel nausea vomiting continuously more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the weight decreases and interferes with daily activities, it is because there are several factors, namely, hormonal actors, diet, unwanted pregnancy, and psychology.

Motivating Growth in Low-tech Manufacturing Industries

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Naomi HERTZ
Keyword(s):  
Value Chain ◽  
Field Research ◽  
Sustainable Competitive Advantage ◽  
Manufacturing Plants ◽  
Footwear Industry ◽  
Technological Platform ◽  
Qualitative Methodologies ◽  
Developed World ◽  
Depth Interviews

Intensive manual labor enterprises in the developed world face challenges competing with products imported from countries where manufacturing costs are low. This reduces the volume of domestic production and leads to rapid loss of knowledge and experience in production processes. This study focuses on the Israeli footwear industry as a case study. Qualitative methodologies were applied, including in-depth interviews and field observations. A literature review on previous research, and contemporary trends was conducted. The field research examines challenges along the value chain in small factories. It finds that mass production paradigms impose a decentralized process between designers and manufacturers and therefore do not leverage local potential into a sustainable competitive advantage for small factories. The proposed solution is a digital and technological platform for small manufacturing plants. The platform mediates and designs the connections between production, technology, and design and enables the creation of a joint R&D system.

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