scholarly journals Denaturation of the SARS-CoV-2 spike protein under non-thermal microwave radiation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pooya Afaghi ◽  
Michael Anthony Lapolla ◽  
Khashayar Ghandi
Keyword(s):  
Electromagnetic Field ◽  
Body Temperature ◽  
Microwave Radiation ◽  
Human Body ◽  
Viral Entry ◽  
Thermal Denaturation ◽  
Spike Protein ◽  
Heating Effect ◽  
Bulk Heating ◽  
Human Body Temperature

AbstractSARS-CoV-2, the virus that causes COVID-19, is still a widespread threat to society. The spike protein of this virus facilitates viral entry into the host cell. Here, the denaturation of the S1 subunit of this spike protein by 2.45 GHz electromagnetic radiation was studied quantitatively. The study only pertains to the pure electromagnetic effects by eliminating the bulk heating effect of the microwave radiation in an innovative setup that is capable of controlling the temperature of the sample at any desired intensity of the electromagnetic field. This study was performed at the internal human body temperature, 37 °C, for a relatively short amount of time under a high-power electromagnetic field. The results showed that irradiating the protein with a 700 W, 2.45 GHz electromagnetic field for 2 min can denature the protein to around 95%. In comparison, this is comparable to thermal denaturation at 75 °C for 40 min. Electromagnetic denaturation of the proteins of the virus may open doors to potential therapeutic or sanitation applications.

scholarly journals Temperature dependence of the rigid amorphous fraction of poly(butylene succinate)

RSC Advances ◽  
2021 ◽  
Vol 11 (41) ◽  
pp. 25731-25737
Author(s):  
Maria Cristina Righetti ◽  
Maria Laura Di Lorenzo ◽  
Patrizia Cinelli ◽  
Massimo Gazzano
Keyword(s):  
Body Temperature ◽  
Temperature Dependence ◽  
Human Body ◽  
Room Temperature ◽  
Rigid Amorphous Fraction ◽  
Butylene Succinate ◽  
Amorphous Fraction ◽  
Human Body Temperature ◽  
Rigid Amorphous

At room temperature and at the human body temperature, all the amorphous fraction is mobile in poly(butylene succinate).

scholarly journals Design of Monitoring Tool Heartbeat Rate and Human Body Temperature Based on WEB

2018 ◽  
Vol 164 ◽  
pp. 01017 ◽  
Author(s):  
Jalinas ◽  
Wahyu Kusuma Raharja ◽  
Bobby Putra Emas Wijaya
Keyword(s):  
Heart Rate ◽  
Body Temperature ◽  
Human Body ◽  
Average Error ◽  
Web Pages ◽  
Test Results ◽  
Pulse Sensor ◽  
Measurement Results ◽  
Human Body Temperature ◽  
Error Percentage

The heart is one of the most important organs in the human body. One way to know heart health is to measure the number of heart beats per minute and body temperature also shows health, many heart rate and body temperature devices but can only be accessed offline. This research aims to design a heart rate detector and human body temperature that the measurement results can be accessed via web pages anywhere and anytime. This device can be used by many users by entering different ID numbers. The design consists of input blocks: pulse sensor, DS18B20 sensor and 3x4 keypad button. Process blocks: Arduino Mega 2560 Microcontroller, Ethernet Shield, router and USB modem. And output block: 16x2 LCD and mobile phone or PC to access web page. Based on the test results, this tool successfully measures the heart rate with an average error percentage of 2.702 % when compared with the oxymeter tool. On the measurement of body temperature get the result of the average error percentage of 2.18 %.

scholarly journals Decreasing Human Body Temperature in the United States Since the Industrial Revolution

2019 ◽  
Author(s):  
Myroslava Protsiv ◽  
Catherine Ley ◽  
Joanna Lankester ◽  
Trevor Hastie ◽  
Julie Parsonnet
Keyword(s):  
United States ◽  
Body Temperature ◽  
Human Body ◽  
Industrial Revolution ◽  
The United States ◽  
Human Body Temperature

scholarly journals Design of Fixed-Wing and Multi-Copter Hybrid Drone System for Human Body Temperature Measurement during COVID-19 Pandemic

2021 ◽  
Vol 20 ◽  
pp. 31-39
Author(s):  
Zayed Almheiri ◽  
Rawan Aleid ◽  
Sharul Sham Dol
Keyword(s):  
Body Temperature ◽  
Temperature Measurement ◽  
Human Body ◽  
Equivalent Strain ◽  
Simulation Software ◽  
Operational Conditions ◽  
Drag Forces ◽  
Human Body Temperature ◽  
Body Temperature Measurement ◽  
Lift And Drag

The purpose of this research is to conduct aerodynamics study and design a hybrid drone system of fixed-wing and multi-copter. The mission of this drone is to measure human body temperature during COVID19 pandemic. The specific aim of the drone is to fly and cover larger industrial areas roughly about 50 km2 with longer flying time than the conventional drone, of about 1.5 hours. The applications of the simulation software such as XFLR5 and ANSYS have a big impact in identifying areas that need to be improved for the drone system. XFLR5 software was used to compare the characteristics of different airfoils with highest lift over drag, L/D ratio. Based on the airfoil selection, it was found that NACA 4412 airfoil produces the highest L/D ratio. The detailed geometry of the drone system includes a fuselage length of 1.9 meters and wingspan of 2 meters. Moreover, 10 sheets of solar panels were placed along the wing for sustainable flight operation to cover wider areas of mission. The structural analysis was done on ANSYS to test the elastic stress, equivalent strain, deformation, factor of safety pressure as well as lift and drag forces under various operational conditions and payloads. The landing gear was analyzed for harsh landing. ANSYS Computational Fluid Dynamics (CFD) was utilized to study the aerodynamics of the drone at different parameters such as the velocities and angles of attack during the operation. This design ensures the stability of the drone during the temperature measurement phase. The best thermal-imaging camera for such purpose would be the Vue Pro R 336, 45° radiometric drone thermal camera with a resolution of 640 x 512 pixels. This camera has the advantage of a permanent continuous out focus that give the ability of taking measurements even if there was changing on the altitude or any kind of vibrations.

scholarly journals Global transcriptome analysis of Stenotrophomonas maltophilia in response to growth at human body temperature

2021 ◽  
Vol 7 (7) ◽  
Author(s):  
Prashant P. Patil ◽  
Sanjeet Kumar ◽  
Amandeep Kaur ◽  
Samriti Midha ◽  
Kanika Bansal ◽  
...  
Keyword(s):  
Body Temperature ◽  
Human Body ◽  
Transcriptome Analysis ◽  
Stenotrophomonas Maltophilia ◽  
Type Species ◽  
Human Pathogen ◽  
Content Type ◽  
Link Type ◽  
Human Body Temperature ◽  
Opportunistic Human Pathogen

Stenotrophomonas maltophilia is a typical example of an environmental originated opportunistic human pathogen, which can thrive at different habitats including the human body and can cause a wide range of infections. It must cope with heat stress during transition from the environment to the human body as the physiological temperature of the human body (37 °C) is higher than environmental niches (22–30 °C). Interestingly, S. rhizophila a phylogenetic neighbour of S. maltophilia within genus Stenotrophomonas is unable to grow at 37 °C. Thus, it is crucial to understand how S. maltophilia is adapted to human body temperature, which could suggest its evolution as an opportunistic human pathogen. In this study, we have performed comparative transcriptome analysis of S. maltophilia grown at 28 and 37 °C as temperature representative for environmental niches and the human body, respectively. RNA-Seq analysis revealed several interesting findings showing alterations in gene-expression levels at 28 and 37 °C, which can play an important role during infection. We have observed downregulation of genes involved in cellular motility, energy production and metabolism, replication and repair whereas upregulation of VirB/D4 type IV secretion system, aerotaxis, cation diffusion facilitator family transporter and LacI family transcriptional regulators at 37 °C. Microscopy and plate assays corroborated altered expression of genes involved in motility. The results obtained enhance our understanding of the strategies employed by S. maltophilia during adaptation towards the human body.

scholarly journals Fabrication and Characterization of Wrapped Metal Yarns-based Fabric Temperature Sensors

Polymers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1549
Author(s):  
Qian Yang ◽  
Xi Wang ◽  
Xin Ding ◽  
Qiao Li
Keyword(s):  
Mechanical Properties ◽  
Body Temperature ◽  
Heat Source ◽  
Human Body ◽  
Temperature Sensors ◽  
Temperature Sensitive ◽  
Maximum Strain ◽  
Human Body Temperature ◽  
Fabrication And Characterization

Textile temperature sensors are highly in demanded keep a real-time and accurate track of human body temperature for identification of healthy conditions or clinical diagnosis. Among various materials for textile temperature sensors, temperature-sensitive metal fibers have highest precision. However, those metal fibers are mechanically too weak, and break constantly during the weaving process. To enhance the mechanical strength of the metal fibers, this paper proposes to make wrapped metal fibers using wrapping technology, and characterize the effect of wrapped metal yarns on both mechanical properties and sensing behaviors. The wrapped yarns were woven into fabrics, forming the fabric temperature sensors. Results show that strength and maximum strain of the wrapped yarns are 2.69 and 1.82 times of pure Pt fibers. The response time of fabric temperature sensors using wrapped yarns was observed as 0.78 s and 1.1 s longer compared to that using Pt fibers when front and back sides contacted heat source, respectively. It is recommended that the wrapping method should be implemented for the protection of Pt fibers in fabric temperature sensors.

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