scholarly journals Bio-multifunctional noncovalent porphyrin functionalized carbon-based nanocomposite

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Navid Rabiee ◽  
Mojtaba Bagherzadeh ◽  
Amir Mohammad Ghadiri ◽  
Yousef Fatahi ◽  
Nafiseh Baheiraei ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Genetic Material ◽  
Hydroxyl Groups ◽  
Multiwalled Carbon ◽  
One Pot ◽  
Potential Donor ◽  
Hek 293 ◽  
Surface Hydroxyl ◽  
Suitable Space

AbstractHerein, in a one-pot method, the reduced graphene oxide layers with the assistance of multiwalled carbon nanotubes were decorated to provide a suitable space for the in situ growth of CoNi2S4, and the porphyrins were incorporated into the layers as well to increase the sensitivity of the prepared nanostructure. The prepared nanocomposite can establish π–π interactions between the genetic material and on the surface of porphyrin rings. Also, hydrogen bonds between genetic domains and the porphyrin’ nitrogen and the surface hydroxyl groups are probable. Furthermore, the potential donor–acceptor relationship between the d7 transition metal, cobalt, and the genetic material provides a suitable way to increase the interaction and gene loading , and transfections. The reason for this phenomenon was optimized to increase the EGFP by up to 17.9%. Furthermore, the sensing ability of the nanocomposite towards H2O2 was investigated. In this regard, the limit of detection of the H2O2 obtained 10 µM. Also, the in situ biosensing ability in the HEK-293 and PC12 cell lines was evaluated by the addition of PMA. The nanocomposite showed the ability to detect the released H2O2 after adding the minimum amount of 120 ng/mL of the PMA.

scholarly journals Porphyrin Molecules Decorated on Metal–Organic Frameworks for Multi-Functional Biomedical Applications

Biomolecules ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1714
Author(s):  
Navid Rabiee ◽  
Mohammad Rabiee ◽  
Soheil Sojdeh ◽  
Yousef Fatahi ◽  
Rassoul Dinarvand ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Limit Of Detection ◽  
Metal Organic Frameworks ◽  
Protein Structures ◽  
Cellular Protein ◽  
Hydroxyl Groups ◽  
One Pot ◽  
Hydrogen Bond Formation ◽  
Surface Hydroxyl ◽  
Metal Organic

Metal–organic frameworks (MOFs) have been widely used as porous nanomaterials for different applications ranging from industrial to biomedicals. An unpredictable one-pot method is introduced to synthesize NH2-MIL-53 assisted by high-gravity in a greener media for the first time. Then, porphyrins were deployed to adorn the surface of MOF to increase the sensitivity of the prepared nanocomposite to the genetic materials and in-situ cellular protein structures. The hydrogen bond formation between genetic domains and the porphyrin’ nitrogen as well as the surface hydroxyl groups is equally probable and could be considered a milestone in chemical physics and physical chemistry for biomedical applications. In this context, the role of incorporating different forms of porphyrins, their relationship with the final surface morphology, and their drug/gene loading efficiency were investigated to provide a predictable pattern in regard to the previous works. The conceptual phenomenon was optimized to increase the interactions between the biomolecules and the substrate by reaching the limit of detection to 10 pM for the Anti-cas9 protein, 20 pM for the single-stranded DNA (ssDNA), below 10 pM for the single guide RNA (sgRNA) and also around 10 nM for recombinant SARS-CoV-2 spike antigen. Also, the MTT assay showed acceptable relative cell viability of more than 85% in most cases, even by increasing the dose of the prepared nanostructures.

Dynamic Effects in CO Adsorption on Ru/ZSM-5. Part I: Oxidative Disruption of Ru

1992 ◽  
Vol 46 (8) ◽  
pp. 1279-1287 ◽  
Author(s):  
J. Y. Shen ◽  
A. Sayari ◽  
S. Kaliaguine
Keyword(s):  
Diffuse Reflectance ◽  
Direct Evidence ◽  
Co Adsorption ◽  
Hydroxyl Groups ◽  
Surface Hydroxyl ◽  
Surface Hydroxyl Groups ◽  
Diffuse Reflectance Infrared Spectroscopy ◽  
Adsorption Of Co ◽  
Diffuse Reflectance Infrared

In situ diffuse reflectance infrared spectroscopy of CO adsorption on reduced Ru/ZSM-5 reveals that, under appropriate conditions, in addition to the linearly adsorbed CO on metallic Ru particles (at 2045 ± 10 cm−1), two multicarbonyls involving oxidized Ru can be generated. These multicarbonyl species are characterized by IR doublets at 2080 and 2138 cm−1 and at 2086 and 2150 cm−1, respectively. Direct evidence for the consumption of both types of the ZSM-5 surface hydroxyl groups (silanol and Brønsted) during the oxidative adsorption of CO has been obtained. Each of these two OH types is believed to be associated with one of the multicarbonyl species.

In situ spectroscopic studies on vapor phase catalytic decomposition of dimethyl oxalate

2017 ◽  
Vol 19 (11) ◽  
pp. 8034-8045 ◽  
Author(s):  
Shweta Hegde ◽  
Kalsang Tharpa ◽  
Satyanarayana Reddy Akuri ◽  
Rakesh K. ◽  
Ajay Kumar ◽  
...  
Keyword(s):  
Vapor Phase ◽  
Catalytic Decomposition ◽  
Spectroscopic Studies ◽  
Hydroxyl Groups ◽  
Spectroscopic Measurements ◽  
Surface Hydroxyl ◽  
Dimethyl Oxalate ◽  
Catalytic Materials ◽  
Surface Hydroxyl Groups

Dimethyl oxalate (DMO) decomposition was investigated on various catalytic materials. In situ spectroscopic measurements revealed that DMO decomposition is observed more on acidic surfaces and is dependent on the presence of surface hydroxyl groups.

Sulfonated multiwalled carbon nanotubes (MWCNTs) as a new, efficient, and recyclable heterogeneous nanocatalyst for the synthesis of amines

2012 ◽  
Vol 90 (8) ◽  
pp. 701-707 ◽  
Author(s):  
M. M. Doroodmand ◽  
S. Sobhani ◽  
A. Ashoori
Keyword(s):  
Carbon Nanotubes ◽  
Multiwalled Carbon Nanotubes ◽  
Chemical Vapor ◽  
Catalytic Amount ◽  
Multiwalled Carbon ◽  
One Pot ◽  
Heterogeneous Nanocatalyst ◽  
Aldehydes And Ketones ◽  
Simple Filtration

Sulfonated multiwalled carbon nanotubes (MWCNTs) were synthesized by chemical vapor deposition (CVD) as a new and facile one-pot method using acetylene (as the CNT precursor), thiophene (as the sulfur precursor), and ferrocene (for in situ liberation of metal nanoparticles as the CNT nanocatalyst). A low catalytic amount of the resulting sulfonated MWCNTs with a turnover number (TON) up to 980 and a turnover frequency (TOF) up to 11 160 h–1 was utilized as a new and recyclable heterogeneous nanocatalyst for the efficient one-pot synthesis of various amines (secondary and tertiary) by direct reductive amination of aldehydes and ketones using NaBH4. The catalyst was easily isolated from the reaction mixture by simple filtration and reused at least five times without significant degradation in activity.

Hydroxyl-rich nanoporous carbon nanosheets synthesized by a one-pot method and their application in the in situ preparation of well-dispersed Ag nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (116) ◽  
pp. 96062-96066 ◽  
Author(s):  
Xiaodi Guo ◽  
Gaili Liu ◽  
Shuang Yue ◽  
Jing He ◽  
Lianying Wang
Keyword(s):  
Ag Nanoparticles ◽  
High Surface ◽  
High Surface Area ◽  
Nanoporous Carbon ◽  
Hydroxyl Groups ◽  
Ag Nps ◽  
One Pot ◽  
Carbon Nanosheets ◽  
In Situ Preparation

Nanoporous carbon nanosheets (CNSs) with high surface area have been synthesized by pyrolysis of organic–inorganic precursor. The CNSs with rich hydroxyl groups display remarkable reactivity and capability for in situ loading ultrafine Ag NPs.

HYPERBRANCHED ALIPHATIC POLYESTER MODIFIED ACTIVATED CARBON PARTICLES WITH HOMOGENIZED SURFACE GROUPS

2007 ◽  
Vol 14 (06) ◽  
pp. 1025-1032 ◽  
Author(s):  
PENG LIU ◽  
LIUXUE ZHANG
Keyword(s):  
Activated Carbon ◽  
Photoelectron Spectroscopy ◽  
Active Sites ◽  
Hydroxyl Groups ◽  
Surface Groups ◽  
Aliphatic Polyester ◽  
One Pot ◽  
Surface Hydroxyl ◽  
Carbon Particles ◽  
Activated Carbon Particles

The hyperbranched aliphatic polyester grafted activated carbon (HAPE-AC), was successfully prepared by the simple "one-pot" method. The surface functional groups of commercial activated carbon particles were homogenized to hydroxyl groups by being oxidized with nitric acid and then reduced with lithium tetrahydroaluminate ( LiAlH 4) at first. Secondly, the surface hydroxyl groups were used as the active sites for the solution polycondensation of the AB2 monomer, 2, 2-bis(hydroxymethyl)propionic acid (bis-MPA), with the catalysis of p-toluenesulfonic acid (p-TSA). The homogenization of the surface groups of the activated carbon particles and the graft polymerization of the hyperbranched aliphatic polyester were investigated by X-ray photoelectron spectroscopy (XPS) technique. The products were also characterized with Fourier transform infrared (FT-IR) and scanning electron microscope (SEM). The competitive adsorption properties of the products toward the heavy metal ions ( Cu (II), Hg (II), Zn (II), and Cd (II)) also proved the translations of the surface groups.

Indium Bromide-catalyzed Unprecedented Hydrogenolysis: A Novel One-Pot Synthesis of Per-O-Acetylated β-carboxymethyl O and S-glycosides

2020 ◽  
Vol 24 (8) ◽  
pp. 900-908
Author(s):  
Ram Naresh Yadav ◽  
Amrendra K Singh ◽  
Bimal Banik
Keyword(s):  
Asymmetric Synthesis ◽  
Chiral Auxiliary ◽  
Bioactive Molecules ◽  
One Pot ◽  
Enantiomerically Pure ◽  
Stereoselective Glycosylation ◽  
One Pot Synthesis ◽  
Wide Range

Numerous O (oxa)- and S (thia)-glycosyl esters and their analogous glycosyl acids have been accomplished through stereoselective glycosylation of various peracetylated bromo sugar with benzyl glycolate using InBr3 as a glycosyl promotor followed by in situ hydrogenolysis of resulting glycosyl ester. A tandem glycosylating and hydrogenolytic activity of InBr3 has been successfully investigated in a one-pot procedure. The resulting synthetically valuable and virtually unexplored class of β-CMGL (glycosyl acids) could serve as an excellent potential chiral auxiliary in the asymmetric synthesis of a wide range of enantiomerically pure medicinally prevalent β-lactams and other bioactive molecules of diverse medicinal interest.

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