scholarly journals Role of fibre and fruit in the Mediterranean diet to protect against myocardial infarction: a case–control study in Spain

2002 ◽  
Vol 56 (8) ◽  
pp. 715-722 ◽  
Author(s):  
MA Martínez-González ◽  
E Fernández-Jarne ◽  
E Martínez-Losa ◽  
M Prado-Santamaría ◽  
C Brugarolas-Brufau ◽  
...  
2014 ◽  
Vol 18 (4) ◽  
pp. 713-720 ◽  
Author(s):  
Federica Turati ◽  
Claudio Pelucchi ◽  
Carlotta Galeone ◽  
Delphine Praud ◽  
Alessandra Tavani ◽  
...  

AbstractObjectiveTo add epidemiological data on the association of adherence to the Mediterranean diet with non-fatal acute myocardial infarction (AMI) in a Southern European population.DesignHospital-based case–control study. Conformity to the traditional Mediterranean diet was assessed through a score (i.e. the Mediterranean diet score, MDS) based on nine dietary components (high consumption of vegetables, legumes, fruit and nuts, cereals, and fish and seafood; high ratio of monounsaturated to saturated lipids; low consumption of dairy and meat; and moderate alcohol consumption). The score ranged between 0 (lowest adherence) and 9 (highest adherence). The association of the MDS, or its components, with the risk of AMI was evaluated through multiple logistic regression models, controlling for potential confounding variables.SettingThe study was conducted in the greater Milan area (Italy) between 1995 and 2003.SubjectsSeven hundred and sixty patients with a first episode of non-fatal AMI and 682 controls.ResultsHigh consumption of vegetables and legumes were inversely associated with non-fatal AMI risk. As compared with MDS<4, the OR of non-fatal AMI were 0·85 (95 % CI 0·65, 1·12) for MDS of 4–5 and 0·55 (95 % CI 0·40, 0·75) for MDS≥6, with a trend in risk (P<0·01). Results were consistent in strata of selected risk factors and an apparently stronger association emerged for individuals with a lower BMI.ConclusionsThe Mediterranean diet is inversely associated with the risk of non-fatal AMI in this Southern European population.


Nutrition ◽  
2019 ◽  
Vol 65 ◽  
pp. 185-190 ◽  
Author(s):  
Paola Scarano ◽  
Marco Magnoni ◽  
Vittoria Vergani ◽  
Martina Berteotti ◽  
Nicole Cristell ◽  
...  

2014 ◽  
Vol 66 (5) ◽  
pp. 810-817 ◽  
Author(s):  
Niki Mourouti ◽  
Meropi D. Kontogianni ◽  
Christos Papavagelis ◽  
Petrini Plytzanopoulou ◽  
Tonia Vassilakou ◽  
...  

2021 ◽  
Vol 27 (6) ◽  
pp. 587-594
Author(s):  
Ulas Akbulut ◽  
Ishak Isik ◽  
Atike Atalay ◽  
Ismail Topal

Background: Functional constipation is often seen in children, affecting quality of life and imposing a considerable burden on health care services. The Mediterranean diet is associated with a lower risk of functional gastrointestinal disorders. Aims: This study aimed to evaluate the relationship between functional constipation and adherence to the Mediterranean diet in Turkish children aged 6–18 years. Methods: In this case–control study, 221 children with functional constipation (cases) were selected from a paediatric gastroenterology clinic between May 2018 and September 2019, and 230 children without constipation (controls) were randomly selected from those attending a well-child check-up. Cases and controls were matched on sex, age and socioeconomic characteristics. Compliance with the Mediterranean diet was assessed using the KIDMED index score. Multivariable logistic regression analysis was used to analyses the data. Results: KIDMED index scores in cases and controls were 4.0 (SD = 2.5) and 6.3 (SD = 2.4), respectively (P < 0.001). Odds ratios for functional constipation were 0.23 (95% confidence interval (CI): 0.13–0.38) for KIDMED index score 4–7 and 0.05 (95% CI: 0.03–0.11) for score ≥ 8 compared with the lowest category (score ≤ 3; P < 0.001). A negative correlation was observed between age and adherence to the Mediterranean diet. Conclusion: Good adherence to the Mediterranean diet was associated with a lower risk of functional constipation, and adherence to the Mediterranean diet decreased with age. Education on nutrition and health is warranted to help maintain and improve the health of young people in Turkey.


1999 ◽  
Vol 82 (07) ◽  
pp. 14-18 ◽  
Author(s):  
Francesco Zito ◽  
Augusto Di Castelnuovo ◽  
Andria D’Orazio ◽  
Riccardo Negrini ◽  
Domenico De Lucia ◽  
...  

SummaryThe contribution of Helicobacter pylori (HP) infection to the risk of myocardial infarction was evaluated. The role of fibrinogen and its genetic control as a possibile mechanism by which HP may influence myocardial infarction risk was explored in this context. A case-control study was performed in 101 patients with myocardial infarction and in 101 controls.HP infection was associated with an increased risk of myocardial infarction independently for confounding variables (OR 4.1, CI95: 1.8-9.4). HP infection was significantly associated with higher levels of fibrinogen, both in cases and in controls. Furthermore, there was an additive effect of HP infection and B2 allele of BclI fibrinogen poly-morphism in increasing fibrinogen levels. HP infection showed a stronger effect on the risk of myocardial infarction in B2 allele carriers (OR 7.6, CI95: 1.8-31.6) as compared to subjects carrying the B1B1 genotype (OR 3.3, CI95: 1.2-9.2).We showed that a previous HP infection is a risk factor for myocardial infarction. An increase in fibrinogen levels is a possible mechanism by which HP may act. Concomitant conditions, like a genetic predisposition in increasing fibrinogen levels, seem to further increase the effect of HP on myocardial infarction risk.


2011 ◽  
Vol 162 (4) ◽  
pp. 717-724 ◽  
Author(s):  
Christina-Maria Kastorini ◽  
Haralampos J. Milionis ◽  
Aggeliki Ioannidi ◽  
Kallirroi Kalantzi ◽  
Vassilios Nikolaou ◽  
...  

2003 ◽  
Vol 89 (5) ◽  
pp. 673-678 ◽  
Author(s):  
J. M. Martin-Moreno ◽  
L. Gorgojo ◽  
R. A. Riemersma ◽  
J. Gomez-Aracen ◽  
J. D. Kark ◽  
...  

Zn is an essential mineral. The role of Zn in atherosclerosis is not clear. Epidemiological studies, which have reported contradictory results, are limited by the use of serum Zn levels as a marker of intake. We assessed the association of toenail Zn, which integrates dietary Zn intake over 3 to 12 months, with the risk of a first myocardial infarction. Toenail Zn concentrations were determined by neutron activation analysis in the European multi-centre case–control study on antioxidants, myocardial infarction and breast cancer. This multi-centre case–control study included 684 cases and 724 controls from eight European countries and Israel. Toenail Zn levels of controls (adjusted for age and study centre) were positively associated with age, α-tocopherol and Se, but not with additional dietary variables or with classical risk factors for CHD. Average toenail Zn was 106·0 mg/kg in cases (95 % CI 103·1, 108·9) and 107·5 mg/kg in controls (95 % CI 104·5, 110·7). After controlling for cardiovascular risk factors and for centre, the adjusted odds ratios of myocardial infarction for quintiles 2–5 of toenail Zn with respect to the first quintile were 0·97 (95 % CI 0·59, 1·58), 1·15 (95 % CI 0·72, 1·85), 0·91 (95 % CI 0·56, 1·50), and 0·85 (95 % CI 0·52, 1·39). ThePfor trend was 0·45. In conclusion toenail Zn levels (reflecting long-term dietary intake) were not significantly associated with acute myocardial infarction.


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