Bioactive comparison of main components from unripe fruits of Rubus chingii Hu and identification of the effective component

2015 ◽  
Vol 6 (7) ◽  
pp. 2205-2214 ◽  
Author(s):  
Tian-Tian Zhang ◽  
Li Yang ◽  
Jian-Guo Jiang

Dried and unripe fruit of Rubus chingii Hu, known as “Fu-pen-zi” in Chinese, has been used as a food and tonic in China for a long time.

2019 ◽  
Vol 67 (25) ◽  
pp. 7025-7039 ◽  
Author(s):  
Yue Chen ◽  
Zhongqin Chen ◽  
Qingwen Guo ◽  
Xudong Gao ◽  
Qiqi Ma ◽  
...  

2020 ◽  
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pp. 126964 ◽  
Author(s):  
Yue Chen ◽  
Leilei Xu ◽  
Yajie Wang ◽  
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...  

MedChemComm ◽  
2017 ◽  
Vol 8 (8) ◽  
pp. 1673-1680 ◽  
Author(s):  
Tian-Tian Zhang ◽  
Ya-Jun Liu ◽  
Li Yang ◽  
Jian-Guo Jiang ◽  
Jing-Wen Zhao ◽  
...  

Rubus chingii Hu, namely “Fu-pen-zi” in Chinese, has been used as a functional food in China for a long time.


2020 ◽  
Vol 1 (1) ◽  
pp. 19-23
Author(s):  
Diah Willis L ◽  
Thomas Priyasmanu ◽  
Wahyu Panji A ◽  
D. H. Praswanto ◽  
E. Y. Setyawan

Development in the current development sector has grown rapidly, in this development we can see a good potential to be developed, namely the development of bricks with good quality compared to using red bricks which production takes a long time. Batako is an alternative that can be used in the construction of a building, because currently the price of red brick is quite high because the production cost is quite expensive. Besides, the price of firewood used for cooking red brick is getting difficult. Meanwhile, the demand for brick gradually increased because brick was one of the main components in building construction. So it needs to be developed in making brick blocks because the time is relatively short in the drying process. Therefore the community service team made a brick making machine with a vibration system for compaction and a faster production process in brick making using a machine that has been made, so that it can increase partner income, who previously produced 120 pieces with a manual system using a machine that could produce 500 pieces of brick per day.


2019 ◽  
Vol 27 (2) ◽  
pp. 117-127
Author(s):  
Yulia M Andriyanova ◽  
Irina V Sergeeva ◽  
Yulia M Mokhonko ◽  
Natalia N Gusakova

The influence of recreation being a set of measures to restore health and recreation, on the main components of forest phytocenoses in specially protected natural territories of the Tatishchevsky district of the Saratov region has been studied for the first time. These phytocenoses have been intensively used for tourism for a long time. The intensity and visits activity of protected areas has been determined; the recreational capacity of territorial objects has been studied. The degree of forest landscapes has been revealed in specially protected natural territories. The findings allow predicting the future state of the natural resources of the Saratov region and can be taken into account when assessing their optimal use.


2021 ◽  
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Author(s):  
Zhen Chen ◽  
Jingyong Jiang ◽  
Xiaobai Li ◽  
Yiwen Xie ◽  
Zexin Jin ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1911
Author(s):  
Jiang Wan ◽  
Xiao-Juan Wang ◽  
Nan Guo ◽  
Xi-Ying Wu ◽  
Juan Xiong ◽  
...  

During a phytochemical investigation of the unripe fruits of Rubus chingii Hu (i.e., Fructus Rubi, a traditional Chinese medicine named “Fu-Pen-Zi”), a number of highly oxygenated terpenoids were isolated and characterized. These included nine ursane-type (1, 2, and 4–10), five oleanane-type (3, 11–14), and six cucurbitane-type (15–20) triterpenoids, together with five ent-kaurane-type diterpenoids (21–25). Among them, (4R,5R,8R,9R,10R,14S,17S,18S,19R,20R)-2,19α,23-trihydroxy-3-oxo-urs-1,12-dien-28-oic acid (rubusacid A, 1), (2R*,4S*,5R*,8R*,9R*,10R*,14S*,17S*, 18S*,19R*,20R*)-2α,19α,24-trihydroxy-3-oxo-urs-12-en-28-oic acid (rubusacid B, 2), (5R,8R,9R,10R, 14S,17R,18S,19S)-2,19α-dihydroxy-olean-1,12-dien-28-oic acid (rubusacid C, 3), and (3S,5S,8S,9R, 10S,13R,16R)-3α,16α,17-trihydroxy-ent-kaur-2-one (rubusone, 21) were previously undescribed. Their chemical structures and absolute configurations were elucidated on the basis of spectroscopic data and electronic circular dichroism (ECD) analyses. Compounds 1 and 3 are rare naturally occurring pentacyclic triterpenoids featuring a special α,β-unsaturated keto-enol (diosphenol) unit in ring A. Cucurbitacin B (15), cucurbitacin D (16), and 3α,16α,20(R),25-tetrahydroxy-cucurbita-5,23- dien-2,11,22-trione (17) were found to have remarkable inhibitory effects against NF-κB, with IC50 values of 0.08, 0.61, and 1.60 μM, respectively.


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