scholarly journals Antimicrobial activity of nano-sized silver colloids stabilized by nitrogen-containing polymers: the key influence of the polymer capping

RSC Advances ◽  
2018 ◽  
Vol 8 (20) ◽  
pp. 10873-10882 ◽  
Author(s):  
Carin C. S. Batista ◽  
Lindomar J. C. Albuquerque ◽  
Iris de Araujo ◽  
Brunno L. Albuquerque ◽  
Fernanda D. da Silva ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Polymer Coating ◽  
Chemical Nature ◽  
Silver Colloids ◽  
Kinetic Release ◽  
Polymer Capping ◽  
Polymer Stabilized

The antimicrobial activity of silver colloids depends on Ag+kinetic release that is governed by the chemical nature of the polymer coating in polymer-stabilized assemblies.

The Chemistry Of Antibiofilm Phytocompounds.

2020 ◽  
Vol 20 ◽  
Author(s):  
Dibyajit Lahiri ◽  
Moupriya Nag ◽  
Sayantani Garai ◽  
Rina Rani Ray
Keyword(s):  
Antimicrobial Activity ◽  
Antibiotic Resistance ◽  
Antibiotic Therapy ◽  
Antimicrobial Agents ◽  
Chemical Nature ◽  
Rapid Development ◽  
Wide Spread ◽  
Chronic Infections ◽  
Therapeutic Uses

: Phytocompounds are long known for their therapeutic uses due to their competence as antimicrobial agents. The antimicrobial activity of these bioactive compounds manifests their ability as an antibiofilm agent and is thereby proved to be competent to treat the wide spread of biofilm-associated chronic infections. Rapid development of antibiotic resistance in bacteria has made the treatment of these infections almost impossible by conventional antibiotic therapy, which forced in the switch over to the use of phytocompounds. The present overview deals with the classification of the huge array of phytocompounds according to their chemical nature, detection of their target pathogen, and elucidation of their mode of action.

Microfluidic-assisted synthesis of uniform polymer-stabilized silver colloids

2021 ◽  
Vol 618 ◽  
pp. 126438
Author(s):  
Carin C.S. Batista ◽  
Alessandro Jäger ◽  
Brunno L. Albuquerque ◽  
Ewa Pavlova ◽  
Petr Stepánek ◽  
...  
Keyword(s):  
Silver Colloids ◽  
Polymer Stabilized

scholarly journals 1217. Predicting the Efficacy of an Antimicrobial Surface Coating Utilizing X-Ray Fluorescence Spectroscopy (XRF)

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S437-S438
Author(s):  
Parham Asgari ◽  
Jie Fang ◽  
Val Price ◽  
Don DeClue ◽  
Gavri Grossman ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Stainless Steel ◽  
Fluorescence Spectroscopy ◽  
Polymer Coating ◽  
Test Organism ◽  
Polymer Coatings ◽  
Antimicrobial Efficacy ◽  
X Ray ◽  
Durable Polymer ◽  
The Relationship

Abstract Background Contaminated surfaces are a critical risk factor for transmitting infectious disease. Current disinfection products provide short-term antimicrobial action; however, these surfaces can be re-contaminated within hours after cleaning. To address this limitation, long-lasting antimicrobial polymer coatings have been developed as an adjunct to traditional disinfecting and cleaning protocols. Due to the micro-scale thickness and transparency of the coating, confirmation of its presence on surfaces is difficult with conventional methods; therefore, this study explores a novel approach to measuring durable polymer coatings on stainless steel coupons to validate their presence and relative antimicrobial activity. Methods In this study, we utilized a hand-held X-ray fluorescence spectroscopy (XRF) analyzer to quantitatively evaluate the amount of antimicrobial polymer coating deposited on stainless steel test surfaces. Stainless steel surfaces with amounts of coating ranging from 0.12 to 3.60 mg/in.2 were analyzed for their XRF profile using a hand-held spectrometer. Additionally, the relationship between the XRF spectra and antimicrobial activity was evaluated using a modified version of an existing sanitization protocol for hard surfaces using Staphylococcus epidermidis as the test organism. Results Comparison of the amount of antimicrobial polymer coating (in mg) and the XRF values (photon count) revealed a calibration curve with a high degree of linearity (R2 = 0.993) especially for surfaces that had lower mass (Figure 1). In addition, the relationship between XRF values and antimicrobial efficacy also were found to be well-correlated with a logarithmic trend (R2 = 0.9308) (Figure 2). Conclusion The observed trends between coating mass, XRF value and antimicrobial efficacy suggests that these analytical techniques are viable options for determining the presence of invisible antimicrobial polymer coatings. Additionally, laboratory-based calibration curves based on XRF values can be used to predict the level of antimicrobial activity of surfaces that have been treated with polymer coatings. These findings suggest that the use of a hand-held XRF spectrometer can be a rapid and cost-effective method for assessing the presence and efficacy of polymer coatings. Disclosures All authors: No reported disclosures.

scholarly journals Emerging technologies for long-term antimicrobial device coatings: advantages and limitations

2017 ◽  
Vol 242 (8) ◽  
pp. 788-798 ◽  
Author(s):  
Erika L Cyphert ◽  
Horst A von Recum
Keyword(s):  
Antimicrobial Activity ◽  
Polymer Coating ◽  
Intrinsic Properties ◽  
Short Term ◽  
Device Failure ◽  
Advantages And Disadvantages ◽  
The Past ◽  
Drug Eluting ◽  
Implanted Device

Over the past 20 years, the field of antimicrobial medical device coatings has expanded nearly 30-fold with technologies shifting their focus from diffusion-only based (short-term antimicrobial eluting) coatings to long-term antimicrobial eluting and intrinsically antimicrobial functioning materials. A variety of emergent coatings have been developed with the goal of achieving long-term antimicrobial activity in order to mitigate the risk of implanted device failure. Specifically, the coatings can be grouped into two categories: those that use antibiotics in conjunction with a polymer coating and those that rely on the intrinsic properties of the material to kill or repel bacteria that come into contact with the surface. This review covers both long-term drug-eluting and non-eluting coatings and evaluates the inherent advantages and disadvantages of each type while providing an overview of variety applications that the coatings have been utilized in. Impact statement This work provides an overview, with advantages and limitations of the most recently developed antibacterial coating technologies, enabling other researchers in the field to more easily determine which technology is most advantageous for them to further develop and pursue.

Potential of polymer stabilized nano-liposomes to enhance antimicrobial activity of nisin Z against foodborne pathogens

LWT ◽  
2018 ◽  
Vol 96 ◽  
pp. 98-110 ◽  
Author(s):  
Taskeen Niaz ◽  
Saima Shabbir ◽  
Tayyaba Noor ◽  
Abdur Rahman ◽  
Habib Bokhari ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Foodborne Pathogens ◽  
Nisin Z ◽  
Polymer Stabilized

scholarly journals Combined effect of biopriming and polymer coating on chemical constituents of root exudation in chilli (Capsicum annuum L.) cv. K 2 seedlings

2016 ◽  
Vol 8 (4) ◽  
pp. 2141-2154 ◽  
Author(s):  
S. Sathya ◽  
S. Lakshmi ◽  
S. Nakkeeran
Keyword(s):  
Antimicrobial Activity ◽  
Volatile Compounds ◽  
Capsicum Annuum ◽  
Root Exudates ◽  
Polymer Coating ◽  
Chemical Constituents ◽  
Root Exudation ◽  
Hexadecanoic Acid ◽  
Capsicum Annuum L ◽  
Two Stages

A study was carried out to analyze the different volatile compounds in bioprimed chilli (Capsicum annuum L.) seedlings of 15 and 30 day old. A common compound found in two stages of chilli seedlings was hydroxylamine, dimethoxydimethyl silane, hexadecanoic acid, 15-methyl- methyl ester. Majority of the compounds in bacterized seedlings had antimicrobial activity. The results on GCMS analysis revealed that, root exudates collected from 15 and 30 days old bacterized seedlings with B. amyloliquefaciens VB7 and polymer coating released more number of volatile compounds (65 and 20 compounds respectively) than control (5 and 15 compounds respectively). The root exudates of 15 day old seedling released more volatile compounds (65 nos) than 30 days (20 nos) old seedling.

scholarly journals Encapsulation of Essential Oils within a Polymeric Liposomal Formulation for Enhancement of Antimicrobial Efficacy

2010 ◽  
Vol 5 (9) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Sandy F. van Vuuren ◽  
Lisa C. du Toit ◽  
Ashleigh Parry ◽  
Viness Pillay ◽  
Yahya E. Choonara
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oils ◽  
Polymer Coating ◽  
Chitosan Solution ◽  
Antimicrobial Efficacy ◽  
Polymeric Coating ◽  
Limiting Factor ◽  
Layer By Layer ◽  
Positive Effects ◽  
The Stability

Essential oils and their constituents are known to possess antimicrobial activity; however, their inherent volatility is a limiting factor. In order to exploit the antimicrobial efficacy of essential oils, encapsulation within polymeric liposomal systems was undertaken. The liposomes were subsequently polymer-coated in order to further enhance the stability of the formulations. Essential oils distilled from Artemisia Afra, Eucalyptus Globulus and Melaleuca alternifolia were encapsulated into diastearoyl phosphatidylcholine and diastearoyl phosphatidylethanolamine liposomes employing a reverse phase evaporation methodology. A polyelectrolyte coating was then applied via the layer-by-layer self-deposition technique. A batch of the liposomes was polymer-coated with a 0.15%w/v chitosan solution. Using the minimum inhibitory concentration assay, the liposome-encapsulated, unencapsulated and polymer-coated liposome-encapsulated essential oils were compared in order to observe whether the antimicrobial efficacy was improved with encapsulation and polymer coating. Fractional inhibitory concentrations (FICs) were calculated in order to determine the antimicrobial interactions amongst the lipoid components, polymer coating and essential oils (synergistic, additive, indifferent and antagonistic interactions). With the exception of A. afra, microbial growth was inhibited at lower concentrations for the encapsulated formulations in comparison with the non-encapsulated oils. Synergistic to additive interactions were noted for encapsulated E. globulus (ΣFIC values 0.25-0.45) and M. alternifolia (ΣFIC values 0.26-0.52) formulations. The addition of the polymer coating did not enhance antimicrobial activity, but owing to their positive effects on membrane stability, its presence is important as a means of extending the shelf life of these formulations. Additionally, the presence of the polymeric coating availed the essential oil at a slower rate. This investigation is a stepping stone towards the promotion of the antimicrobial use of essential oils. The added benefits are that essential oils not only provide effective antimicrobial efficacy, but also promote a “greener” consumerism. Within liposomes, they will enhance dermato-cosmetic properties and increase the marketing image of the final product.

Synthesis of Phosphoric Polymer Coating Solution with Antimicrobial Activity and Flame Retardant Efficiency

Polymer Korea ◽  
2011 ◽  
Vol 35 (5) ◽  
pp. 431-437
Author(s):  
Sang Kyum Kim ◽  
In Soo Lee ◽  
Sang Hee Seo ◽  
Seong Ho Choi
Keyword(s):  
Antimicrobial Activity ◽  
Flame Retardant ◽  
Polymer Coating ◽  
Coating Solution

scholarly journals In vitro kinetic release study, antimicrobial activity and in vivo toxicity profile of a kojic acid ester-based nanoemulsion for topical application

RSC Advances ◽  
2020 ◽  
Vol 10 (71) ◽  
pp. 43894-43903
Author(s):  
Sharifah Nurfadhlin Afifah Syed Azhar ◽  
Siti Efliza Ashari ◽  
Syahida Ahmad ◽  
Norazlinaliza Salim
Keyword(s):  
Drug Delivery ◽  
Antimicrobial Activity ◽  
Controlled Release ◽  
Topical Application ◽  
Kojic Acid ◽  
Toxicity Profile ◽  
Kinetic Release ◽  
Release Study

Nanoemulsions have emerged as novel vehicles for drug delivery that allow sustained or controlled release for topical application.

Release of Neurosecretion in the Crayfish Sinus Gland

1968 ◽  
Vol 26 ◽  
pp. 150-151
Author(s):  
Richard R. Shivers
Keyword(s):  
Chemical Nature ◽  
Storage Site ◽  
Neurosecretory Granules ◽  
Sinus Gland ◽  
Diameter Class ◽  
Dense Membrane ◽  
Neurohemal Organ ◽  
Dense Vesicles

The sinus gland is a neurohemal organ located in the crayfish eyestalk and represents a storage site for neurohormones prior to their release into the circulation. The sinus gland contains 3 classes of dense, membrane-limited granules: 1) granules measuring less than 1000 Å in diameter, 2) granules measuring 1100-1400 Å in diameter, and 3) granules measuring 1500-2000 Å in diameter. Class 3 granules are the most electron-dense of the granules found in the sinus gland, while class 2 granules are the most abundant. Generally, all granules appear to undergo similar changes during release.Release of neurosecretory granules may be initiated by a preliminary fragmentation of the “parent granule” into smaller, less dense vesicles which measure about 350 Å in diameter (V, Figs. 1-3). A decrease in density of the granules prior to their fragmentation has been observed and may reflect a change in the chemical nature of the granule contents.

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