A multi-functional drug delivery system based on polyphenols for efficient tumor inhibition and metastasis prevention

2020 ◽  
Vol 8 (2) ◽  
pp. 702-711 ◽  
Author(s):  
Si Chen ◽  
Jin-Xuan Fan ◽  
Di-Wei Zheng ◽  
Fan Liu ◽  
Xuan Zeng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Treatment ◽  
Tumor Inhibition ◽  
Integrated Therapy

A multi-functional drug delivery system EINP@DOX, which integrated therapy, imaging and anti-metastatic functions, was constructed to realize a systematic tumor treatment.

scholarly journals Dual-modal imaging and excellent anticancer efficiency of cisplatin and doxorubicin loaded NaGdF4:Yb3+/Er3+ nanoparticles

RSC Advances ◽  
2018 ◽  
Vol 8 (39) ◽  
pp. 22216-22225 ◽  
Author(s):  
Zhiyang Zhang ◽  
Jiayi Sheng ◽  
Miaomiao Zhang ◽  
Xiaoyan Ma ◽  
Zhirong Geng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Inhibition

The drug delivery system NaGdF4–CDDP–DOX showed best tumor inhibition capacity both in vitro and in vivo.

scholarly journals Improving Tumoral Acidic pH-Responsive Drug Efficiency Based on GO@Au Nanocomposite

2020 ◽  
Author(s):  
Mingqing Tang ◽  
Pengliang Xin ◽  
Hongjun Lin ◽  
Huangen Li
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Tumor Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Infrared Light ◽  
Tumor Inhibition ◽  
Release Drug

Abstract Background: to accurately deliver drugs to the lesion site and realize its timed and quantitative release is the focus of tumor therapy. In this paper, a tumor targeted near-infrared light controlled release drug delivery system integrating hyperthermia and chemotherapy was successfully constructed by combining tumor hyperthermia and chemotherapy. Results: by hydrothermal method, Au nanoparticles were firstly loaded onto the GO surface to obtain GO@Au nanocomposites, then PEG was loaded onto the GO@Au by pH sensitive hydrazone bond to obtain GO@Au-PEG, and DOX is finally loaded onto the GO surface via π-π stacking. The target controlled release drug delivery system showed good tumor targeting property, can be the efficient transfer of drug to the tumor cells, and the tumor cells in near-infrared light control of DOX release. In vivo tumor inhibition experiments in mice, the targeted drug delivery system showed obvious tumor inhibition characteristics and had good effects of hyperthermia and chemotherapy. Conclusions: therefore, this tumor targeted near-infrared controlled release drug delivery system has great potential in tumor therapy.

Multicompartmentalized vesosomes containing DOX loaded liposomes and 5FU loaded liposomes for synergistic tumor treatment

2019 ◽  
Vol 43 (12) ◽  
pp. 4895-4899 ◽  
Author(s):  
Xunan Zhang ◽  
Wei Zong ◽  
Jialiang Wang ◽  
Mingdong Dong ◽  
Wenlong Cheng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Treatment ◽  
Cancer Treatments

A multicompartmentalized vesosome drug delivery system was developed for enhanced cancer treatments.

Multifunctional zinc-based hollow nanoplatforms as a smart pH-responsive drug delivery system to enhance in vivo tumor-inhibition efficacy

2018 ◽  
Vol 139 ◽  
pp. 172-180 ◽  
Author(s):  
Jinghai Yang ◽  
Fei Gao ◽  
Donglai Han ◽  
Lili Yang ◽  
Xiangwang Kong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Responsive ◽  
Tumor Inhibition

Hexosomes based on cholesterol and phosphatidylcholine: a new drug delivery system for curcumin release

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
AR Bilia ◽  
G Capecchi ◽  
MC Salvatici ◽  
B Isacchi ◽  
MC Bergonzi
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
New Drug

Evaluation of transdermal drug-delivery system of capsaicin

2017 ◽  
Author(s):  
A Uzunovic ◽  
S Pilipovic ◽  
A Sapcanin ◽  
Z Ademovic
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Transdermal Drug Delivery ◽  
Transdermal Drug Delivery System
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