Multicompartmentalized vesosomes containing DOX loaded liposomes and 5FU loaded liposomes for synergistic tumor treatment

2019 ◽  
Vol 43 (12) ◽  
pp. 4895-4899 ◽  
Author(s):  
Xunan Zhang ◽  
Wei Zong ◽  
Jialiang Wang ◽  
Mingdong Dong ◽  
Wenlong Cheng ◽  
...  

A multicompartmentalized vesosome drug delivery system was developed for enhanced cancer treatments.

2021 ◽  
Vol 11 ◽  
pp. e00685
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Youssef Khayati ◽  
Ibrahim Sbai El Otmani

2020 ◽  
Vol 8 (2) ◽  
pp. 702-711 ◽  
Author(s):  
Si Chen ◽  
Jin-Xuan Fan ◽  
Di-Wei Zheng ◽  
Fan Liu ◽  
Xuan Zeng ◽  
...  

A multi-functional drug delivery system EINP@DOX, which integrated therapy, imaging and anti-metastatic functions, was constructed to realize a systematic tumor treatment.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Weiwei Mu ◽  
Qihui Chu ◽  
Yongjun Liu ◽  
Na Zhang

AbstractAlthough notable progress has been made on novel cancer treatments, the overall survival rate and therapeutic effects are still unsatisfactory for cancer patients. Chemoimmunotherapy, combining chemotherapeutics and immunotherapeutic drugs, has emerged as a promising approach for cancer treatment, with the advantages of cooperating two kinds of treatment mechanism, reducing the dosage of the drug and enhancing therapeutic effect. Moreover, nano-based drug delivery system (NDDS) was applied to encapsulate chemotherapeutic agents and exhibited outstanding properties such as targeted delivery, tumor microenvironment response and site-specific release. Several nanocarriers have been approved in clinical cancer chemotherapy and showed significant improvement in therapeutic efficiency compared with traditional formulations, such as liposomes (Doxil®, Lipusu®), nanoparticles (Abraxane®) and micelles (Genexol-PM®). The applications of NDDS to chemoimmunotherapy would be a powerful strategy for future cancer treatment, which could greatly enhance the therapeutic efficacy, reduce the side effects and optimize the clinical outcomes of cancer patients. Herein, the current approaches of cancer immunotherapy and chemoimmunotherapy were discussed, and recent advances of NDDS applied for chemoimmunotherapy were further reviewed.


Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
AR Bilia ◽  
G Capecchi ◽  
MC Salvatici ◽  
B Isacchi ◽  
MC Bergonzi

2017 ◽  
Author(s):  
A Uzunovic ◽  
S Pilipovic ◽  
A Sapcanin ◽  
Z Ademovic

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