Water-soluble conjugated polymer with near-infrared absorption for synergistic tumor therapy using photothermal and photodynamic activity

2019 ◽  
Vol 55 (59) ◽  
pp. 8615-8618 ◽  
Author(s):  
Sirong Zhou ◽  
Changgang Yang ◽  
Lixia Guo ◽  
Yunxia Wang ◽  
Guofeng Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Infrared Absorption ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Water Soluble ◽  
Nir Light ◽  
Photodynamic Activity

A novel NIR-absorbing and water-soluble conjugated polymer (PTDBD) for single-NIR-light induced synergetic photothermal/photodynamic therapy was developed.

Photoactive conjugated polymer/graphdiyne nanocatalyst for CO2 reduce into CO in living cells for hypoxia tumor treatment

2021 ◽  
Author(s):  
Endong Zhang ◽  
Zicheng Zuo ◽  
Wen Yu ◽  
Hao Zhao ◽  
Shengpeng Xia ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Conjugated Polymer ◽  
Tumor Therapy ◽  
Living Cells ◽  
Tumor Treatment ◽  
Treatment Efficiency ◽  
Therapy Strategy ◽  
Co Gas

Carbon monoxide (CO) gas therapy has grown to be an emerging tumor therapy strategy to avoid low treatment efficiency of photodynamic therapy (PDT) caused by the hypoxia tumor microenvironment. However,...

Biodegradable Nano-photosensitizer with Photoactivatable Singlet Oxygen Generation for Synergistic Phototherapy

2021 ◽  
Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Promising Method ◽  
Normal Cells ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...

Ultralow-intensity near infrared light synchronously activated collaborative chemo/photothermal/photodynamic therapy

2020 ◽  
Vol 8 (2) ◽  
pp. 607-618 ◽  
Author(s):  
Renlu Han ◽  
Keqi Tang ◽  
Yafei Hou ◽  
Jiancheng Yu ◽  
Chenlu Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Nir Light

An ultralow-intensity 808 nm NIR light with 0.25 W cm−2 synchronously activated collaborative Chemo/Photothermal/Photodynamic therapy system was developed.

scholarly journals Single-atom replacement as a general approach towards visible-light/near-infrared heavy-atom-free photosensitizers for photodynamic therapy

2020 ◽  
Vol 11 (26) ◽  
pp. 6701-6708 ◽  
Author(s):  
Juan Tang ◽  
Lushun Wang ◽  
Axel Loredo ◽  
Carson Cole ◽  
Han Xiao
Keyword(s):  
Photodynamic Therapy ◽  
Oxygen Atom ◽  
Visible Light ◽  
Near Infrared ◽  
Heavy Atom ◽  
Single Atom ◽  
General Strategy ◽  
Nir Light ◽  
Fluorescent Molecules

Thio-based photosensitizer: a general strategy for preparing visible/NIR light absorbing heavy-atom-free photosensitizers was developed by performing a simple sulfur-for-oxygen atom substitution within existing fluorescent molecules.

A zwitterionic red-emitting water-soluble conjugated polymer with high resistance to nonspecific binding for two-photon cell imaging and good singlet oxygen production capability

2021 ◽  
Author(s):  
Yan-Qin Huang ◽  
Shan-Shan Jiang ◽  
Li-Xiang Pan ◽  
Rui Zhang ◽  
Kun-Lin Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Conjugated Polymers ◽  
Singlet Oxygen ◽  
High Resistance ◽  
Conjugated Polymer ◽  
Cell Imaging ◽  
Water Soluble ◽  
Oxygen Production ◽  
Nonspecific Binding ◽  
Two Photon

Water-soluble conjugated polymers (WSCPs) with dual capability of two-photon imaging and singlet oxygen (1O2) production have become one type of the most promising agents in noninvasive imaging guided photodynamic therapy...

Design and synthesis of water-soluble polyaminated chlorins and bacteriochlorins – With near-infrared absorption

2013 ◽  
Vol 98 (3) ◽  
pp. 609-614 ◽  
Author(s):  
Nicolas Drogat ◽  
Christelle Gady ◽  
Robert Granet ◽  
Vincent Sol
Keyword(s):  
Infrared Absorption ◽  
Near Infrared ◽  
Water Soluble ◽  
Design And Synthesis

scholarly journals SHG-enhanced NIR-excited in vitro photodynamic therapy using composite nanoparticles of barium titanate and rose Bengal

RSC Advances ◽  
2019 ◽  
Vol 9 (14) ◽  
pp. 8056-8064 ◽  
Author(s):  
Xianhe Sun ◽  
Zhang Ji ◽  
Sailing He
Keyword(s):  
Photodynamic Therapy ◽  
Barium Titanate ◽  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Rose Bengal ◽  
Near Infrared ◽  
Second Harmonic ◽  
Composite Nanoparticles ◽  
Nir Light

Composite nanoparticles of barium titanate and rose Bengal are used to achieve second harmonic generation (SHG) enhanced photodynamic therapy excited by near infrared (NIR) light.

scholarly journals Effect of Top Channel Thickness in Near Infrared Organic Phototransistors with Conjugated Polymer Gate-Sensing Layers

Electronics ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 1493 ◽  
Author(s):  
Jisu Park ◽  
Hwajeong Kim ◽  
Taehoon Kim ◽  
Chulyeon Lee ◽  
Dong-Ik Song ◽  
...  
Keyword(s):  
Light Intensity ◽  
Conjugated Polymer ◽  
Near Infrared ◽  
Drain Current ◽  
Thickness Effect ◽  
Theoretical Maximum ◽  
Nir Light ◽  
Channel Thickness

Here, we report the thickness effect of top channel layers (CLs) on the performance of near infrared (NIR)-detecting organic phototransistors (OPTRs) with conjugated polymer gate-sensing layers (GSLs). Poly(3-hexylthiophene) (P3HT) was employed as a top CL, while poly[{2,5-bis-(2-octyldodecyl)-3,6-bis-(thien-2-yl)-pyrrolo[3,4-c]pyrrole-1,4-diyl}-co-{2,2′-(2,1,3-benzothiadiazole)-5,5′-diyl}] (PODTPPD-BT) was used as a GSL. The thickness of P3HT CLs was varied from 10 to 70 nm. Three different wavelengths of NIR light (λ = 780, 905, and 1000 nm) were introduced and their light intensity was fixed to 0.27 mW cm−2. Results showed that all fabricated devices exhibited typical p-channel transistor behaviors and the highest drain current in the dark was obtained at the P3HT thickness (t) of 50 nm. The NIR illumination test revealed that the NIR photoresponsivity (RC) of GSL-OPTRs could be achieved at t = 50 nm irrespective of the NIR wavelength. The maximum RC of the optimized devices (t = 50 nm) reached ca. 61% at λ = 780 nm and ca. 47% at λ = 1000 nm compared to the theoretical maximum photoresponsivity.

An upconversion nanoplatform with extracellular pH-driven tumor-targeting ability for improved photodynamic therapy

Nanoscale ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 4432-4441 ◽  
Author(s):  
Fujin Ai ◽  
Na Wang ◽  
Xiaoman Zhang ◽  
Tianying Sun ◽  
Qi Zhu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Extracellular Ph ◽  
Upconversion Nanoparticles ◽  
Nir Light ◽  
Targeting Ability

Upconversion nanoparticles (UCNPs) are widely utilized for photodynamic therapy (PDT) due to their specific upconverting luminescence that utilizes near infrared (NIR) light to excite photosensitizers (PSs) for PDT.

Sign in / Sign up

Export Citation Format

Share Document