scholarly journals Predicting aromatic exciplex fluorescence emission energies

2019 ◽  
Vol 21 (20) ◽  
pp. 10325-10335 ◽  
Author(s):  
Rachel A. Krueger ◽  
Guillaume Blanquart

Analysis of PAH exciplex TDDFT fluorescence energies shows a linear relationship between the mean monomer HOMO–LUMO gap and complex fluorescence.

PEDIATRICS ◽  
1996 ◽  
Vol 98 (6) ◽  
pp. 1149-1153
Author(s):  
Ernest Z. Phillipos ◽  
Murray A. Robertson ◽  
Paul J. Byrne

Objectives. To assess the efficacy of Doppler echocardiography (DE) in the quantification of patent ductus arteriosus (PDA) shunt volume and to correlate PDA shunt volume with clinical outcome in infants with hyaline membrane disease. Methods. Ninety-eight DE studies were performed in 30 preterm ventilated infants with hyaline membrane disease within the first 24 hours of age and then at 48-hour intervals to a maximum of three studies while ventilated with a final study after extubation. Right and left ventricular outputs (QRV and QLV, respectively) and PDA flow were calculated using cross-sectional area and flow velocity integrals. Left atrial-to-aortic root diameter measurements were also taken. Clinical outcomes were correlated with the shunt fraction (QLV/QRV). Results. QLV/QRV demonstrated a linear relationship with the left atrial-to-aortic root diameter ratio (n = 92; r = .79). In the absence of a PDA (n = 33 studies), QRV versus QLV demonstrated a linear relationship (r = .88). In the presence of a PDA (n = 64 studies) the mean QLV (334 ± 133 ml/kg per minute) was significantly greater than the mean QRV (237 ± 84 ml/kg per minute). There was a linear relationship between QLV - QRV (PDA shunt volume) and PDA flow (n = 60; r = .84). In studies with exclusive left-to-right shunting at the PDA (n = 48), the mean QLV - QRV (112 ± 83 ml/kg per minute) was significantly higher than in those with bidirectional shunting (n = 16; mean QLV - QRV = 50 ± 27 ml/kg per minute). Two infants with severe intraventricular hemorrhage (IVH grade 3) and two infants with periventricular leukomalacia (PVL) had significantly higher QLV/QRV (2.09 ± 0.36 and 1.67 ± 0.02 respectively) than those with no IVH (n = 6; QLV/QRV = 1.31 ± 0.18) or those with IVH grades 1 and 2 (n = 8; QLV/QRV = 1.48 ± 0.27). There was no difference in QLV/QRV in infants with or without bronchopulmonary dysplasia retinopathy of prematurity. Necrotizing enterocolitis did not develop in any of the 30 infants. Conclusion. PDA shunt volume can be quantified by DE. Larger studies are needed to correlate clinical outcome with QLV/QRV.


1982 ◽  
Vol 62 (1) ◽  
pp. 183-188 ◽  
Author(s):  
R. RIOUX

Barley (Hordeum vulgare L. ’Champlain’) was grown with quackgrass (Agropyron repens (L.) Beauv.) at various densities for 3 yr. According to the regression analysis, a linear relation is appropriate to describe the relationship between yield of barley and biomass or density of quackgrass. A greater proportion of yield variability was explained by density (64%) than by biomass (40%). Density is then a better criterion than biomass to predict yield lost in barley. The linear relationship between barley yield and the shoot density of quackgrass is estimated by the following equation: yield barley = 345.3–0.5682 dens, quackgrass. An increase of 10 shoots/m2 in the mean density of quackgrass resulted in a mean loss of 6 g/m2 in the yield of barley.


2021 ◽  
Author(s):  
Solange Suli ◽  
Matilde Rusticucci ◽  
Soledad Collazo

<p>Small variations in the mean state of the atmosphere can cause large changes in the frequency of extreme events. In order to deepen and extend previous results in time, in this work we analyzed the linear relationship between extreme and mean temperature (Τ) on a climate change scale in Argentina. Two monthly extreme indices, cold nights (TN10) and warm days (TX90), were calculated based on the quality-controlled daily minimum and maximum temperature data provided by the Argentine National Meteorological Service from 58 conventional weather stations located over Argentina in the 1977–2017 period. Subsequently, we evaluated the relationship between the linear trends of extremes and mean temperature on a seasonal basis (JFM, AMJ, JAS, and OND). Student's T-test was performed to analyze their statistical significance at 5%. Firstly, positive (negative) and significant linear regressions were found between TX90 (TN10) trends and mean temperature trends for the four studied seasons. Therefore, an increase in the Τ-trend maintains a linear relationship with significant increase (decrease) of warm days (cold nights). Moreover, we found that JFM was the one with the highest coefficient of determination (0.602 for hot extremes and 0.511 for cold extremes), implying that 60.2% (51.1%) of the TX90 (TN10) trend could be explained as a function of the Τ-trend by a linear regression. In addition, in the JFM (OND) quarter, the TX90 index increased by 7.02 (6.02) % of days each with a 1 ºC increase in the mean temperature. Likewise, the TN10 index decreased by 4.94 (and 4.99) % of days from a 1ºC increase in the mean temperature for the JFM (AMJ) quarter. Finally, it is worthwhile to highlight the uneven behavior between hot and cold extremes and the mean temperature. Specifically, it was observed that the slopes of the linear regression calculated for the TX90 index and Τ presented a higher absolute value than those registered for the TN10 index and Τ. Therefore, a change in the mean temperature affects hot extremes to a greater extent than cold ones in Argentina.</p>


2019 ◽  
Vol 30 (11) ◽  
pp. 1950096
Author(s):  
Yuanchun Ding ◽  
Falu Weng ◽  
Lizhong Yang

Based on simulation, the influence of the doors’ opening degree (DOD) on crowd evacuation is investigated in this paper. First of all, an evacuation model, which has one exit with two doors, is established by utilizing the software Pathfinder. Then, based on the obtained model, some evacuation scenarios are considered. The simulation results indicate, when the DOD is within 115∘–135∘, the time saving rate is more than 13%, and the maximum time saving rate is achieved when the DOD is 125∘. Furthermore, there is a linear relationship between the mean square error and the number of the evacuees. For a small number of evacuees, the total evacuation time is mainly influenced by the distributions of the evacuees, however, as the number of the evacuees increases, it is mainly influenced by the number of the evacuees. Moreover, when the DOD is 125∘, the mean flow rate per unit width (MFRPUW) decreases along with the increasing of exit’s width, however, it increases along with the increasing of exit’s width while the DOD is 180∘. Compared with the 180∘ DOD, the 125∘ DOD can always achieve a higher MFRPUW, and the narrower the exit is, the higher MFRPUW the 125∘ DOD achieves.


2013 ◽  
Vol 37 (3) ◽  
pp. 309-313 ◽  
Author(s):  
S Joshi ◽  
AM Hegde ◽  
K Rai ◽  
S Shetty

Aim- The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience. Method- A total of 120 children aged 4-10yrs were divided into 4 groups of 30 each. Dental caries experience was recorded followed by un-stimulated saliva collection. Results- The mean salivary sialic acid levels of the study group were much higher when compared with the control group, which was statistically significant. A linear relationship between salivary sialic acid levels and dental caries in leukemic children was observed. Conclusion - The findings of our study conclude that salivary sialic acid levels may have a potent activity in dental caries process and can be used as a useful marker in cancer.


1988 ◽  
Vol 24 (3) ◽  
pp. 367-373 ◽  
Author(s):  
Eric Ayeh

SUMMARYYield stability in beans from diverse sources in Malawi was estimated using the statistical parameters of genotype X environment variance, slope and standard error from regression. The heterozygous F2 and the most complex synthetic mixture were very stable, although not significantly different from some pure genotypes. The mean yields of most mixtures were marginally higher than the average of their components. There was a linear relationship between magnitude of diversity and stability. Evidence for heterozygote advantage was demonstrated.


Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 5826-5826
Author(s):  
Cristina Pascual ◽  
Mari­a Jose Penalva ◽  
Ana Pérez-Corral ◽  
Laura Solán ◽  
Sara Redondo ◽  
...  

Abstract Introduction: Extracorporeal photopheresis (ECP) is a treatment modality that entails leukapheresis followed by mixing the buffy coat with 8-methoxypsoralen (8-MOP) and exposing it to UVA light. The buffy coat is then returned to the patient. ECP may be performed employing two different techniques: an on-line and off-line procedure. The off-line system includes two steps: a processing of buffy coat before reinfused to the patient. The treatment is thought to have an immunomodulatory effect and is most commonly used to treat cutaneous T cell lymphoma, acute and chronic graft-versus-host disease (GVHD), and heart and lung allograft rejection. The exact mechanism and optimal cells dose to be treated is unknown. At the present time, a standard protocol is used generally without considering peripheral blood (PB) leukocytes counts or lymphocyte subpopulations (LP) of the patient. With the off-line system, PB leukocytes counts and LP analysis may be useful to choose the amount and distribution of cells to be infused. The first objective of this study is to examine the quantitative correlation between PB LP and the buffy-coat in order to set individualized guidelines of treatment. Once this relationship is understood, the PB LP may serve as a surrogate marker for cell dose treated and help predicting the efficiency of ECP. The second objetive of this study is to examine the mean performance of the buffy coat LP categorized according to PB leukocytes counts (<1.5 x 109/L and >1.5x 109/L). Patients and methods: Twenty two consecutive patients with refractory GVHD were prospectively studied, from november 2009 to may 2014. Apheresis procedures were perfomed with COBE Spectra system (Terumo BCT®, Lakewood, CO, USA; version 7.0) by processing 1.5-2 times the patient blood volume. The product was transferred to a UVA-permeable bag (UVA, Macopharma, France), added 5 mL (0.1 mg) of 8-methoxypsoralen (8-MOP) aqueous solution (S.A.L.F.®, Cenate Sotto, Italy), exposed to UVA irradiation (Macogenic G2, Macopharma®), and then reinfused. Peripheral blood sample was drawn before ECP. Just before reinfused, buffy coat sample was drawn. Spearman correlation analysis was performed between the LP CD3+CD4+, CD3+CD8+, CD19+, NK of the preapheresis peripheral blood patient and the buffy coat infused analyzed by multiparameter flow cytometry 5 colors (FC500-Beckman Coulter®) in the total sample and in three groups according to preapheresis leukocytes counts (<2.5, 2.5-7.5, >7.5x 109/L). The mean performance was calculated: CD3+CD4+, CD3+CD8+, CD19+, NK+ LP count in buffy coat/ CD3+CD4+, CD3+CD8+, CD19+, NK+ PB /ml x treatment volume (ml) x 100. The mean performance of the buffy coat LP categorized according to preapheresis leukocytes counts (<1.5x 109/L and >1.5 109/L) were compared by Mann-Whitney test. Results: A total of 22 patients and 136 procedures were included in the final analysis. CD3+CD4+, CD3+CD8+, CD19+, NK LP in peripheral blood significantly correlated with those in buffy coat collected by COBE Spectra system, r= 0,74, 0.78, 0,92, 0,39 respectively (table 1). The LP mean doses and mean performance in buffy coat infused are specified in Table 1. The correlations was stronger in all LP with PB leukocytes counts <2.5 x 109/L (table2). We have not found any statistical correlation between the performance of the LP CD3+CD4+, CD3+CD8+, CD19+, NK according to PB leukocytes counts (<1.5x109/L and >1.5x109/L). Conclusions: The buffy coat contains great variability in lymphocyte subpopulations with predominant levels of CD3+CD8+. There is a robust linear relationship between all PB and buffy coat LP. The mean performance LP was around 40% and it was not related to very low PB leukocyte count (<1.5x109/L). The correlation was stronger with lower leukocytes counts in PB. If we could demonstrate a relationship between cell doses infused and clinical response, we could plan the necessary dose for each patient according to the PB leukocyte count and LP preapheresis. Figure 1 Figure 1. Figure 2 Figure 2. Disclosures No relevant conflicts of interest to declare.


2021 ◽  
Author(s):  
Ferehiwot Bekele Getaneh ◽  
Yewondwossen Tadesse Mengistu ◽  
Daphne H. Knicely

Abstract Background: The typical pattern of diabetic kidney disease (DKD) which follows glomerular hyperfiltration progressing to persistent albuminuria associated with hypertension and declining glomerular filtration rate (GFR) has changed over the years. The aim of the study is to examine the potential role of Doppler ultrasound in early identification of DKD. Methods: A 137 patients with type 1 or type 2 diabetes mellitus (DM) patients in Ethiopia participated in the study. We analyzed the correlation between resistive index (RI) of intrarenal arteries and clinical characteristics, eGFR and 24-hr urine. We evaluated the linear relationship of RI with multiple variables using multiple regression analysis. Sensitivity, specificity and area under curve (AUC) of the receiver operating curve (ROC) were assessed.Results: Among the 137 participants, 48.9% were patients with type 1 DM and 51.1% with type 2 DM. Mean age ± SD was 42±15 years. The median 24-hr urine protein was 156 (IQR=149.5) mg/24hr. Mean eGFR was 104.26±17.25 (mL/min/1.73 m2). The mean RI was 0.7±0.06. The mean RI was significantly correlated with age and eGFR (r=0.64 & -0.56, P<0.001 respectively). Our multiple regression model relating mean RI to age, eGFR, systolic blood pressure (SBP), diastolic blood pressure (DBP), duration of diabetes and body mass index (BMI) was significant (overall F-test P-value<0.001). The AUC of the ROC curve of mean RI to identify a low eGFR was 0.82 (95% CI, 0.6 to 1). Sensitivity and specificity of 80% and 53% was calculated respectively.Conclusion: A significant linear relationship has been observed between RI and eGFR. This indicates RI values can determine the level of renal function loss with high accuracy.


2020 ◽  
Author(s):  
Mingyang Yu ◽  
Xiaoming Zhu ◽  
Shilong Zhao ◽  
Ailing De ◽  
Yao Zhang ◽  
...  

Abstract Background Previous clinical studies have reported associations between the acromion index (AI), lateral acromion angle (LAA), and critical shoulder angle (CSA) and the occurrence of rotator cuff tears. The objective of this study was to analyze the correlations of these different anatomic parameters. Materials and Methods Healthy Chinese participants ( n = 66) and Chinese patients with rotator cuff tears ( n = 70) identified between January 2014 and October 2015 were included in this study. Standardized true anteroposterior radiographs were used to measure the AI, LAA, and CSA in each study participant. Results The mean AI was significantly larger (0.71 standard deviation [SD], 0.05; range 0.58–0.89 vs. 0.64 SD, 0.06; range 0.55–0.78; P < 0.001), the mean LAA was significantly smaller (77.0° SD, 5.73; range 61.0°–94.5° vs. 82.0° SD, 7.33; range 67.6°–98.3°; P < 0.001), and the mean CSA was significantly larger (36.1° SD, 5.29; range 21.3°–42.4° vs. 31.6° SD, 5.29; range 21.4°–45.8°; P < 0.001) in patients with full-thickness rotator cuff tears compared with healthy participants. Conclusions There were a negative linear relationship between the AI and LAA (rotator cuff tears: R = −0.759, P < 0.01; healthy participants: R = −0.813, P < 0.01) and a positive linear relationship between the AI and CSA (rotator cuff tears: R = 0.854, P < 0.01; healthy participants: R = 0.912, P < 0.01) in patients with rotator cuff tear and healthy participants; we termed this phenomenon “The Acromion Rule.” The AI, LAA, and CSA are independent predictors of rotator cuff tears in a Chinese population.


1986 ◽  
Vol 250 (6) ◽  
pp. C828-C833 ◽  
Author(s):  
C. Cote ◽  
J. A. Faulkner

Extensor digitorum longus (EDL) muscles of rats were grafted with the nerves intact. Sixty days after grafting, single motor units were isolated and characterized in terms of fatigability and morphology. The distribution of fatigue indexes for motor units in control muscles revealed two main peaks, whereas in grafts no clear peaks were observed, fatigue indexes being distributed more evenly over the entire range. This difference in the distribution of fatigue indexes of motor units may explain the increased resistance to fatigue observed for whole grafts compared with whole EDL muscles. An inverse linear relationship was found between maximum tetanic tensions and the fatigue indexes of motor units from control and grafted EDL muscles. The distribution of fiber areas for single motor units was broader in grafts than in control EDL muscles, but the mean innervation ratio was not different. In approximately 20% of the units mapped in grafts, fibers were clustered tightly within a small portion of the total cross section, suggesting axonal sprouting during regeneration.


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