scholarly journals Indicator displacement assays (IDAs): the past, present and future

Author(s):  
Adam C. Sedgwick ◽  
James T. Brewster ◽  
Tianhong Wu ◽  
Xing Feng ◽  
Steven D. Bull ◽  
...  

Indicator displacement assays (IDAs) offer a unique and innovative approach to molecular sensing. This Tutorial review discusses the basic concepts of each IDA strategy and illustrates their use in sensing applications.

2021 ◽  
Author(s):  
Yushu Shi ◽  
Huiyan Xu ◽  
Tongyao Liu ◽  
Shah Zeb ◽  
Yong Nie ◽  
...  

The scheme of the structure of this review includes an introduction from the metal oxide nanomaterials’ synthesis to application in H2 gas sensors—a vision from the past to the future.


Author(s):  
Yijing Tang ◽  
Dong Zhang ◽  
Yanxian Zhang ◽  
Yonglan Liu ◽  
Lirong Cai ◽  
...  

The past decade has witnessed the growing interest and advances in aggregation-induced emission (AIE) molecules as driven by their unique fluorescence/optical properties in particular sensing applications including biomolecule sensing/detection, environmental/health...


Author(s):  
Augustín Görög ◽  
Ingrid Görögová

Abstract Within the solving VEGA 1/0615/12 research project "Influence of 5-axis grinding parameters on the shank cutter´s geometric accuracy", the research team will measure and evaluate geometrical accuracy of the produced parts. They will use the contemporary measurement technology (for example the optical 3D scanners). During the past few years, significant changes have occurred in the field of geometrical accuracy. The objective of this contribution is to analyse the current standards in the field of geometric tolerance. It is necessary to bring an overview of the basic concepts and definitions in the field. It will prevent the use of outdated and invalidated terms and definitions in the field. The knowledge presented in the contribution will provide the new perspective of the measurement that will be evaluated according to the current standards.


Author(s):  
А.А. Эргашев ◽  
Ш.А. Толибжонова

Приведены различные подходы к выявлению основных понятий, связанных с профессиональным педагогическим образованием. Показаны пути повышения профессионализма педагогических кадров. Материалы статьи можно применять при подготовке будущего учителя математики на основе инновационного подхода к обучению. Various approaches to the identification of basic concepts related to professional teacher education are presented. Shown are ways to develop the professionalism of teaching staff. The materials of the article can be used in preparing the future mathematics teacher based on an innovative approach to teach them.


2003 ◽  
Vol 56 (3) ◽  
pp. 309-329 ◽  
Author(s):  
Jianjun Wang ◽  
Runfang Li and ◽  
Xianghe Peng

In this paper, the progress in nonlinear dynamics of gear driven systems in the past twenty years is reviewed, especially the gear dynamic behavior, by considering the backlash and time-varying mesh stiffness of teeth. The basic concepts, the mathematical models and the solving methods for the non-linear dynamics of geared systems are then reviewed. The critical issues for further research on the nonlinear vibration in gear transmission systems are also discussed. There are 204 references cited in this review article.


Author(s):  
Hessah Albanwan ◽  
Rongjun Qin

Remote sensing images and techniques are powerful tools to investigate earth’s surface. Data quality is the key to enhance remote sensing applications and obtaining clear and noise-free set of data is very difficult in most situations due to the varying acquisition (e.g., atmosphere and season), sensor and platform (e.g., satellite angles and sensor characteristics) conditions. With the increasing development of satellites, nowadays Terabytes of remote sensing images can be acquired every day. Therefore, information and data fusion can be particularly important in the remote sensing community. The fusion integrates data from various sources acquired asynchronously for information extraction, analysis, and quality improvement. In this chapter, we aim to discuss the theory of spatiotemporal fusion by investigating previous works, in addition to describing the basic concepts and some of its applications by summarizing our prior and ongoing works.


Antiquity ◽  
1947 ◽  
Vol 21 (83) ◽  
pp. 116-121
Author(s):  
M. E. L. Mallowan

IT is a pity that Hume, who carried the Cartesian system of philosophy to its logical conclusion, lived too early to contemplate the discoveries of the past century in Egypt and Babylonia, for he would readily have understood and assimilated the ancient processes of thought which arose at the dawn of history in Western Asia--‘ And no truth appears to me more evident ’, he said, ‘ than that beasts are endowed with thought and reason as well as man ’. The arguments are developed in section XVI of ‘ The Understanding ’, where there are many delightful passages of special relevance to the ancient concepts about life. Again, he said that a bird, that ‘chooses with such care and nicety the place and materials of the nest, and sits upon her eggs for a due time, and in a suitable season, with all the precaution that a chymist is capable of in the most delicate projection, furnishes us with a lively instance of animal sagacity’. Locke, on the other hand, in his discussion of animal rationale, had refused to be drawn so far. ‘ And if Balaam’s ass had, all his life, discussed as rationally as he did once with his master, I doubt yet whether any one would have thought him worthy the name ‘man’, or allowed him to be of the same species with himself ’. Of these two statements Hume’s approximates more closely to the earliest Asiatic view of life, and it is on these lines that Messrs. Frankfort, Wilson, and Jacobsen have approached their problem, which, briefly put is-how did the early thinkers of the Near East come to say what they did about creation, the state, and man ? Professor and Mrs Frankfort define the earliest mode of thought as an ‘ I-thou ’ relation-ship, by which they mean that the primitive Asiatic conceived of all creation in a reciprocal nexus wherein the material world was percipient as well as perceived, and Professor Wilson elaborates the same theme by saying that for the Egyptians the world was consubstantial, and that their view of life might be defined as monophysite. Pro-fessor Jacobsen’s contribution illustrates to what extent the Mesopotamian view of life conformed with this outlook, for example how salt and grain were conceived of as animate beings in a close relationship with man, responsible and responsive to him. Other ideas peculiar to the Mesopotamian mind are no less clearly stressed, and herein lies the fascination of the book, that we have a comparative examination of the Egyptian, Mesopotamian and Israelite approach to life, for Hebrew theology was cast out of a similar matrix. In a concluding chapter by the Frankforts, we see the dawn of a new intellectual era. The Greek physical philosophers, regardless of the data of experience, carried the old basic concepts of the Egyptians and Mesopotamians from a concrete to an abstract frame and worked them to a reductio ad absurdurn, much as Hume did for the concepts of Cartesian philosophy. Their prescience gave birth to science. Nor should we forget that Thales of Miletus prophesied an eclipse, thereby following in the wake of the Babylonian astronomers, who had made similar observations and recorded them centuries earlier.


2015 ◽  
Vol 9 (2) ◽  
pp. 306-326 ◽  
Author(s):  
Allan Megill

In recent years David Christian and others have promoted “Big History” as an innovative approach to the study of the past. The present paper juxtaposes to Big History an old Big History, namely, the tradition of “universal history” that flourished in Europe from the mid-sixteenth century until well into the nineteenth century. The claim to universality of works in that tradition depended on the assumed truth of Christianity, a fact that was fully acknowledged by the tradition’s adherents. The claim of the new Big History to universality likewise depends on prior assumptions. Simply stated, in its various manifestations the “new” Big History is rooted either in a continuing theology, or in a form of materialism that is assumed to be determinative of human history, or in a somewhat contradictory amalgam of the two. The present paper suggests that “largest-scale history” as exemplified in the old and new Big Histories is less a contribution to historical knowledge than it is a narrativization of one or another worldview. Distinguishing between largest-scale history and history that is “merely” large-scale, the paper also suggests that a better approach to meeting the desire for large scale in historical writing is through more modest endeavors, such as large-scale comparative history, network and exchange history, thematic history, and history of modernization.


Author(s):  
Jukka Tyrkkö

This chapter outlines the state of the art in corpus-based language teaching and digital pedagogy, focusing on the differences between using corpora with present-day and historical data. The basic concepts of corpus-based research such as representativeness, frequency, and statistical significance can be introduced to students who are new to corpus methods, and the application of these concepts to the history of English can deepen students’ understanding of how historical varieties of the language are researched. This chapter will also address some of the key challenges particular to teaching the history of English using corpora, such as dealing with the seemingly counterintuitive findings, non-standard features, and small datasets. Finally, following an overview of available historical corpora and corpus tools, several practical examples of corpus-driven activities will be discussed in detail, with suggestions and ideas on how a teacher might prepare and run corpus-based lessons.


Catalysts ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 236 ◽  
Author(s):  
Taiki Adachi ◽  
Yuki Kitazumi ◽  
Osamu Shirai ◽  
Kenji Kano

Direct electron transfer (DET)-type bioelectrocatalysis, which couples the electrode reactions and catalytic functions of redox enzymes without any redox mediator, is one of the most intriguing subjects that has been studied over the past few decades in the field of bioelectrochemistry. In order to realize the DET-type bioelectrocatalysis and improve the performance, nanostructures of the electrode surface have to be carefully tuned for each enzyme. In addition, enzymes can also be tuned by the protein engineering approach for the DET-type reaction. This review summarizes the recent progresses in this field of the research while considering the importance of nanostructure of electrodes as well as redox enzymes. This review also describes the basic concepts and theoretical aspects of DET-type bioelectrocatalysis, the significance of nanostructures as scaffolds for DET-type reactions, protein engineering approaches for DET-type reactions, and concepts and facts of bidirectional DET-type reactions from a cross-disciplinary viewpoint.


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