Getting the whole story: The role of high-content analysis
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High-content screening (HCS) is the measurement of complex cellular responses in a population of whole cells in parallel. It provides additional knowledge that can be critical when determining which targets to investigate and which lead compounds to pursue. In this article, we highlight the advantages of HCS analysis over traditional biochemical assays, using work on G-protein-coupled receptors (GPCRs) and kinases as examples.
2014 ◽
Vol 19
(7)
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pp. 1079-1089
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2021 ◽
2010 ◽
Vol 30
(5)
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pp. 313-321
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2019 ◽
Vol 20
(20)
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pp. 5139
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2019 ◽
Vol 119
(04)
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pp. 534-541
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