scholarly journals A safe lithium mimetic?: The inositol depletion hypothesis rescues an experimental drug for bipolar disorder

2013 ◽  
Vol 35 (3) ◽  
pp. 16-19
Author(s):  
Grant C. Churchill ◽  
Nisha Singh ◽  
Sridhar Vasudevan
Keyword(s):  
Bipolar Disorder ◽  
Substance Abuse ◽  
Side Effects ◽  
Personal Life ◽  
Van Gogh ◽  
Vincent Van Gogh ◽  
Works Of Art ◽  
Experimental Drug ◽  
The One ◽  
Insight Into

Vincent Van Gogh painted for just 10 years, but produced over 2000 works of art in periods of intense productivity and creativity. However, during these creative periods, his personal life was one of chaos with poor and impulsive decisions relating to finance, career, business, substance abuse, sexuality and romance (sending his severed ear to the object of his affection), and between these periods he was institutionalized with crushing depressions and he eventually took his own life. It is likely that he suffered from what we now know as bipolar disorder1. Insight into mood is not easily conveyed, but we can get a sense of Van Gogh's mood extremes from two of his paintings, both with the theme of a starry night, but one suggesting exuberant mania and one gloomy depression. Surprisingly, the best treatment for bipolar disorder still remains the one first discovered over 60 years ago: the cation lithium2. Nevertheless, lithium's side effects and toxicity have spurred the search for a replacement2,3.

Doctor Gachet, in the kitchen, with the foxglove

2020 ◽  
Vol 30 (12) ◽  
pp. 1856-1865
Author(s):  
Richard D. Mainwaring ◽  
Stephanie Mainwaring
Keyword(s):  
Mental Illness ◽  
Mental Hospital ◽  
Potassium Bromide ◽  
Van Gogh ◽  
Vincent Van Gogh ◽  
Works Of Art ◽  
The World ◽  
Underlying Illness ◽  
The 19Th Century ◽  
Century Science

AbstractVincent van Gogh (1853–1890) is one of the most famous artists in the world. During his 10-year career as an artist, he created more than 850 paintings. These works of art are now displayed in museums around the globe. It is therefore even more surprising that van Gogh sold just one painting during his lifetime. Van Gogh is also well-known for his mental illness. In 1888, at the age of 35, he famously sliced off his left ear. This was followed by multiple mental collapses in early 1889, leading to his admission to a mental hospital. Despite living in the asylum, van Gogh continued to paint and created some of his most beautiful works of art during the year at Saint-Rémy. Tragically, he committed suicide in 1890 at the age of 37. Over the 130 years since his death, there has been much speculation about the underlying illness of Vincent van Gogh. Many of his contemporary physicians felt that he had a form of epilepsy as the cause of his sudden “attacks”. By the last quarter of the 19th century, science and medicine were moving rapidly forward, and there were many medical conditions that had effective treatments. One example is the use of digoxin for the treatment of heart failure, and another is the discovery of potassium bromide for seizures. This paper provides an overview of van Gogh’s mental illness, the treatments that were offered by his contemporaneous physicians, and the role that these factors may have influenced his paintings.

scholarly journals Visual hybridizations in two audiovisual productions

Novos Olhares ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 142-154
Author(s):  
César Biégas Faquin ◽  
Denize Araujo
Keyword(s):  
Frame Of Reference ◽  
Van Gogh ◽  
Vincent Van Gogh ◽  
Works Of Art ◽  
Epic Theatre ◽  
Theoretical Frame

This paper aims to analyze and discuss two films that present hybrid aesthetics: Lars von Trier’s Dogville (2003) and Welchman´s and Kobiela´s Loving Vincent ( 2017). Dogville evokes the theatre language in its construction and develops an intertextual relationship by using Brecht’s epic theatre, while Loving Vincent is a tribute film to Vincent van Gogh, essentially intertextual because it is based on letters that van Gogh once wrote, as well as his own works of art. The theoretical frame of reference on the processes of dialogism, polyphony, hybridization, intermediality and intertextuality is provided by Araujo, Bazin, Bakhtin, Brecht, Kristeva, Metz, Muller, Nagib e Rajewski.

scholarly journals Aristotle and DSM on ‘Bipolar’ Melancholy: Symptoms, Medication, Link to Creativity.

2021 ◽  
Vol 9 (5) ◽  
Author(s):  
Marlies borg
Keyword(s):  
Mental Health ◽  
Bipolar Disorder ◽  
Diagnostic Criteria ◽  
20Th Century ◽  
Sense Of Belonging ◽  
Work Characteristics ◽  
Van Gogh ◽  
Vincent Van Gogh ◽  
Opposite Extreme

That Aristotle connected excellence, creativity to (bipolar) melancholy is known. This article adds depth and detail by distilling from his work characteristics of hot and cold melancholy, placing them in pairs of opposites, and comparing them with the diagnostic criteria for bipolar disorder in DSM. The Greek warned against extreme mood. He named two examples of mythical persons who suffered the tragic consequences; Ajax’ suicide and Hercules’ manic destruction of his wife and children. More recent examples are Vincent van Gogh, who committed suicide and his brother Theo who attacked his wife and child, was interned and finally succumbed from the consequences of extreme mania. Aristotle urged melancholics to temper their mood. For it was only from mild melancholy that sustained creativity could be expected. He advocated hellebore as medicine. His general ethical advice to strive towards the opposite extreme is especially relevant for melancholics. Aristotle’s work on excellence and bipolar melancholy can inspire those confronted with bipolar disorder today to temper their mood. The examples of famous melancholics throughout the ages bring comfort and a sense of belonging. The author, who is stabilized on lithium, holds up the example of the van Gogh family who, lacking the effective the medicine available today, communicated openly with each other about their disorder. With the new 20th century medication, perfected in our own time, it is from increased openness that the major advances in mental health are now to be expected.

Schliemann's discovery of ‘Priam's treasure’: a re-examination of the evidence

1984 ◽  
Vol 104 ◽  
pp. 96-115 ◽  
Author(s):  
David A. Traill
Keyword(s):  
Present Article ◽  
Fiftieth Anniversary ◽  
Personal Life ◽  
Scholarly Work ◽  
Complex Character ◽  
Subsequent Research ◽  
The One ◽  
Fresh Insight ◽  
Insight Into ◽  
New View

The importance of Schliemann's excavations at Troy, Mycenae and elsewhere is beyond dispute. Yet the aura of greatness which his remarkable achievements have rightly conferred on his name has tended to blur our perception of the man himself. Psychoanalytic studies by W. G. Niederland have offered fresh insight into his complex character, but it is the paper given by W. M. Calder III on the one hundred and fiftieth anniversary of his birth that marks the beginning of the new sceptical attitude to Schliemann. Calder pointed out that Schliemann's autobiographical writings contain many false claims and purely fictitious episodes which biographers have uncritically accepted as fact. This new view of Schliemann as an unreliable witness, which, incidentally, was held by many of his contemporaries, has now been confirmed and expanded by subsequent research.It is principally in matters of his personal life that recent studies have exposed Schliemann's propensity for lies and fraud. However, G. Korres has shown that in his scholarly work too Schliemann did not shrink from seriously misrepresenting the truth. It is the purpose of the present article to demonstrate that even Schliemann's archaeological reports are vitiated by this kind of behaviour. We are not here concerned with Schliemann's interpretations of his discoveries.

scholarly journals Discourse Study of Genre: Autobiography

2015 ◽  
Vol 5 (4) ◽  
pp. 154
Author(s):  
Mohammed Osman
Keyword(s):  
Personal Life ◽  
Personal Account ◽  
The Real ◽  
Personal Story ◽  
Works Of Art ◽  
Insight Into

<p>What arouses our interest is curiosity to know about others. What is an autobiography? The dictionary says: “A personal account of one’s own life especially for publication”. Autobiographies offer insight into the mode of consciousness of others especially in the case of men of notable achievement to know the personal story of well-known events, of motives and intentions that are hidden behind them. This type of knowledge is interesting and instructive.</p><p>Unlike novel we are won over by the hero, in the case of the real hero of the autobiography he is won over by his achievements. We admire him by knowing him intimately and by peeping into his privacy. Autobiographies are works of art that keep us spellbound and fascinating. Autobiography is a form in which a writer speaks of himself and events of his personal life which he had experienced.</p>

scholarly journals Loving Vincent: Online Exhibition as an Innovative Form of Presenting Visual Art in Ukraine

2021 ◽  
pp. 145-152
Author(s):  
Iryna Chmelyk
Keyword(s):  
Visual Art ◽  
Main Idea ◽  
Van Gogh ◽  
Feature Film ◽  
Vincent Van Gogh ◽  
Animated Films ◽  
Art Works ◽  
Art Research ◽  
Insight Into

The article considers the online exhibition and art events Loving Vincent as the relevant forms of exhibition of art works, the main idea of which is to promote the work of Vincent van Gogh and the art of the animated films in Ukraine. The aim of the paper isto highlight the importance of the latest forms of visual art representation in Ukraine on the example of the online exhibition Loving Vincent and a number ofrelated events dedicated to the world’s first full-length eponymous animated feature film about the life of Vincent van Gogh. The role of Ukrainian artists in the process of working on the film is also highlighted. The methodology of work includes a set of culturological and art research methods and approaches. In particular, empirical observations, analysis of the source base and video materials contribute to the comprehensive coverage of the process of organization and realization of the Loving Vincent exhibition. The interviews with the organizers, screenwriters, and artists helped to get a deep insight into the specifics of working on the film. Descriptive and analytical methods contributed to the formation of a comprehensive view regarding the innovative forms of representation of visual artworks in Ukraine. On the basis of factual material, a synthetic comprehension of problems and prospects of development ofsuch newest exposition forms as virtual excursions and online exhibitions were formed. Emphasis is also made on the participation of Ukrainian artists in the largescale international art projects that leads to the creation and development of new opportunities of the representation of contemporary art

When Romania met the Cohesion Policy. Regional governance in-between national conventions and European ideals

2018 ◽  
Vol 18 (2) ◽  
pp. 127-148 ◽  
Author(s):  
Alexandru Brad
Keyword(s):  
Regional Policy ◽  
Development Planning ◽  
Regional Governance ◽  
Theoretical Ground ◽  
Cohesion Policy ◽  
Redistributive Policy ◽  
Policy Context ◽  
Core Areas ◽  
The One ◽  
Insight Into

This article is about the practice of territorial governance emerging at the junction of European Union-sanctioned ideals and Romanian development-planning traditions. On the one hand, the European agenda emphasises a smart, inclusive, sustainable model of economic growth. However, the persisting centralised workings of the Romanian state significantly alters the scope of regional interventions. As such, while core cities grew their economies swiftly, peripheral places were left in an unrelenting stagnation. My first aim is to provide a theoretical ground for a practicecentred approach to understanding territorial governance. Second, by drawing on Romania’s regional policy context as an example, I give an insight into how practices of partnership and competition fare in a context of ongoing territorial polarisation. I conclude by emphasising the need for a regional redistributive policy mechanism, one which should enable and assist non-core areas to access capacities for defining and implementing development projects.

Costumes and Choreography from Bodenwieser's Trunk: The Coat as Affective Memory

2019 ◽  
Vol 37 (1) ◽  
pp. 89-110
Author(s):  
Rachel Fensham
Keyword(s):  
Modern Dance ◽  
Human Condition ◽  
Personal Life ◽  
Creative Thought ◽  
Cain And Abel ◽  
Embodied Research ◽  
The Many ◽  
The One ◽  
Material Evidence ◽  
Selection Of

The Viennese modern choreographer Gertrud Bodenwieser's black coat leads to an analysis of her choreography in four main phases – the early European career; the rise of Nazism; war's brutality; and postwar attempts at reconciliation. Utilising archival and embodied research, the article focuses on a selection of Bodenwieser costumes that survived her journey from Vienna, or were remade in Australia, and their role in the dramaturgy of works such as Swinging Bells (1926), The Masks of Lucifer (1936, 1944), Cain and Abel (1940) and The One and the Many (1946). In addition to dance history, costume studies provides a distinctive way to engage with the question of what remains of performance, and what survives of the historical conditions and experience of modern dance-drama. Throughout, Hannah Arendt's book The Human Condition (1958) provides a critical guide to the acts of reconstruction undertaken by Bodenwieser as an émigré choreographer in the practice of her craft, and its ‘materializing reification’ of creative thought. As a study in affective memory, information regarding Bodenwieser's personal life becomes interwoven with the author's response to the material evidence of costumes, oral histories and documents located in various Australian archives. By resurrecting the ‘dead letters’ of this choreography, the article therefore considers how dance costumes offer the trace of an artistic resistance to totalitarianism.

Marx, Silk Poems, and the Pretext of Qualities

2020 ◽  
Vol 151 (1) ◽  
pp. 96-126
Author(s):  
Kathryn Crim
Keyword(s):  
The Other ◽  
Use Value ◽  
Working Day ◽  
The One ◽  
Insight Into

Karl Marx’s comments on silk manufacture in “The Working Day” chapter of Capital, volume 1, demonstrate how “quality”—usually associated with “use value”—has been mobilized by capital to naturalize industrialized labor. Putting his insight into conversation with a recent multimedia poetic project, Jen Bervin’s Silk Poems (2016–17), this essay examines the homology between, on the one hand, poetry’s avowed task of fitting form to content and, on the other, the ideology of labor that fits specific bodies to certain materials and tasks.

Metamorphosen des Autors im Internet

2018 ◽  
Vol 2018 (1) ◽  
pp. 73-82
Author(s):  
Julia Genz
Keyword(s):  
Web 2.0 ◽  
Digital Media ◽  
Intrinsic Value ◽  
The Other ◽  
Cultural Conditions ◽  
Works Of Art ◽  
Periodic Schedule ◽  
Literary Authorship ◽  
The One ◽  
Death Of The Author

Digital media transform social options of access with regard to producers, recipients, and literary works of art themselves. New labels for new roles such as »prosumers « and »wreaders« attest to this. The »blogger« provides another interesting new social figure of literary authorship. Here, some old desiderata of Dadaism appear to find a belated realization. On the one hand, many web 2.0 formats of authorship amplify and widen the freedom of literary productivity while at the same time subjecting such production to a periodic schedule. In comparison to the received practices of authors and recipients many digital-cultural forms of narrating engender innovative metalepses (and also their sublation). Writing in the net for internet-publics enables the deliberate dissolution of the received autobiographical pact with the reader according to which the author’s genuine name authenticates the author’s writing. On the other hand, the digital-cultural potential of dissolving the autobiographical pact stimulates scandals of debunking and unmasking and makes questions of author-identity an issue of permanent contestation. Digital-cultural conditions of communication amplify both: the hideand- seek of authorship as well as the thwarting of this game by recipients who delight in playing detective. In effect, pace Foucault’s and Barthes’ postulates of the death of the author, the personality and biography of the author once again tend to become objects of high intrinsic value

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