Identification of signalling cascades involved in red blood cell shrinkage and vesiculation
Keyword(s):
After screening two libraries of small bioactive molecules and kinase inhibitors, we identified several signalling pathways to be involved in red blood cell (RBC) shrinkage and vesiculation. These include the Jak (Janus kinase)–STAT (signal transducer and activator of transcription) pathway, phosphoinositide 3-kinase (PI3K)–Akt pathway, the Raf–MEK (mitogen-activated protein kinase kinase)–ERK (extracellular signal-regulated kinase) pathway and GPCR (G protein-coupled receptor) signalling.
2014 ◽
Vol 42
(1)
◽
pp. 59-62
◽
2006 ◽
Vol 97
(4)
◽
pp. 957-967
◽
2009 ◽
Vol 29
(15)
◽
pp. 4250-4261
◽
2002 ◽
Vol 185
(7)
◽
pp. 921-926
◽
2008 ◽
Vol 40
(12)
◽
pp. 2815-2825
◽