Roles of p38 MAPKs in invasion and metastasis
2012 ◽
Vol 40
(1)
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pp. 79-84
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Keyword(s):
P38 Mapk
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Cells from primary tumours need to go through several steps to become fully metastatic. During this process, cancer cells acquire the ability to invade, migrate across the surrounding tissue, enter into the circulation and colonize distant organs. In the present paper, we review recent progress in understanding how the p38 MAPK (mitogen-activated protein kinase) signalling pathway participates in the different steps of metastasis. Experimental evidence suggests that tumour cells need to modulate p38 MAPK activity levels to successfully metastasize.
2001 ◽
Vol 280
(5)
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pp. H1970-H1981
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2014 ◽
Vol 2014
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pp. 1-12
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2001 ◽
Vol 276
(50)
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pp. 46792-46797
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Thymocyte development past the CD4+CD8+stage requires an active p38 mitogen-activated protein kinase
2015 ◽
Vol 67
(10)
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pp. 1380-1392
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