Conclusions and recommendations from the Helene Harris Memorial Trust Fourth Biennial International Forum on Ovarian Cancer 11–14 May 1993, Toronto, Canada

1994 ◽  
Vol 4 (2) ◽  
pp. 135-143 ◽  
Author(s):  
T. Blackett ◽  
F. Sharp
Keyword(s):  
Ovarian Cancer ◽  
Tumor Suppressor Genes ◽  
Malignant Tumors ◽  
Full Range ◽  
Brca1 Gene ◽  
Future Research ◽  
Relationship Of ◽  
The Relationship

The Helene Harris Memorial Trust organizes biennial international meetings of leading clinicians and scientists to discuss progress in the understanding and treatment of ovarian cancer. The conclusions of this meeting, together with recommendations for future research are published as a guide to others working in this field.The 107 conclusions and recommendations presented cover the full range of current topics in ovarian cancer research including the biology of early and borderline tumors, the relationship of benign to malignant tumors,in vitromodels, the role of cytokines, genetic epidemiology, oncogenes and tumor suppressor genes, allele loss, localization of the BRCA1 gene, DNA ploidy in prognosis, the therapeutic use of interferon, platinum and taxoid drugs, screening with panels of tumor antigensm immunotherapy and potenial for gene therapy.

scholarly journals The Moderating Role of Intellectual Capital between Relationship of Bank Specific Factors and Credit Risk of Islamic Banks

2019 ◽  
Vol 2 (4) ◽  
pp. 79-87
Author(s):  
Muhammad Nawaz ◽  
Alias Mat Nor ◽  
Habibah Tolos
Keyword(s):  
Credit Risk ◽  
Intellectual Capital ◽  
Management Policy ◽  
Annual Reports ◽  
Future Research ◽  
Islamic Banks ◽  
Relationship Of ◽  
The Relationship ◽  
Moderating Role

Purpose-The Objective of this study is to investigate the moderating role of Intellectual Capital between the relationship of Bank internal factor and Credit Risk in Islamic banks of Pakistan. Design/Methodology-Panel data are obtained from annual reports of 4 Islamic banks of Pakistan from the period 2006 to 2017. These are analyzed using hierarchical regression techniques, via Eviews 9 software. Findings-The results showed that intellectual capital significantly moderates the relationship of bank internal variable and credit risk in Islamic banks in Pakistan. Practical Implications-The study found that Intellectual Capital is a very important driver for credit risk. The investment in Intellectual Capital may lower the credit risk which will further help in the growth and sustainability of the bank and hence the growth in the economy. The results of the study will be useful for bank management, policy maker, and regulator and academia for future research.

Theoretical Perspectives on Listening

1998 ◽  
Vol 18 ◽  
pp. 3-19 ◽  
Author(s):  
Tony Lynch
Keyword(s):  
Language Skills ◽  
Future Research ◽  
Discourse Comprehension ◽  
Complex Dynamic ◽  
The Past ◽  
Factors Influencing ◽  
Theoretical Perspectives ◽  
Relationship Of ◽  
The Relationship

Research into listening over the past three decades has, above all, highlighted the fundamental intricacy of the processes involved. In order to make sense of spoken messages, listeners may need to integrate information from a range of sources: phonetic, phonological, prosodic, lexical, syntactic, semantic, and pragmatic. The fact that we achieve all this in real time as the message unfolds makes listening “complex, dynamic, and fragile” (Celce-Murcia 1995:366). In this review I consider research into four aspects of these complexities: processes (e.g., speech recognition, discourse comprehension, and memory); the role of context; factors influencing listening; and the relationship of listening with other language skills. Finally I suggest likely directions for future research into listening.

scholarly journals HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Ellen M. Tedaldi ◽  
Nancy L. Minniti ◽  
Tracy Fischer
Keyword(s):  
Hiv Infection ◽  
Research Priorities ◽  
Neurocognitive Disorders ◽  
Current Status ◽  
Future Research ◽  
Diagnostic Strategies ◽  
Immunodeficiency Virus ◽  
Relationship Of ◽  
The Relationship

The prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and neurologic complications. These comorbidities confound the diagnosis, assessment, and interventions for neurocognitive disorders. In this review, we discuss the role of several key comorbid factors that may contribute significantly to the development and progression of HIV-related neurocognitive impairment, as well as the current status of diagnostic strategies aimed at identifying HIV-infected individuals with impaired cognition and future research priorities and challenges.

scholarly journals Relationship of Personality Traits and Gender Role Attitudes: A Comparison of Traditional and non- Traditional Professionals

2012 ◽  
Vol 3 (8) ◽  
pp. 271-279
Author(s):  
Khaizran Zahra ◽  
Rubina Hanif .
Keyword(s):  
Gender Role ◽  
Personality Traits ◽  
Linear Regression Analysis ◽  
Gender Role Attitudes ◽  
Self Control ◽  
Future Research ◽  
And Gender ◽  
Relationship Of ◽  
The Relationship

This study was conducted to examine the relationship of personality traits (i.e., dominance, self-acceptance, self-control, flexibility, sociability, capacity for status and communality) and Gender Role attitudes among professionals of traditional and non-traditional occupations using selected scales from Urdu Version of California Personality Inventory (CPI) and Gender Role Attitudes Scale. A sample of 152 professionals from traditional and non-traditional occupations (criteria of defining traditional and nontraditional professions were based on literature). The findings suggested positive relationship among personality traits and gender role attitudes. The linear Regression analysis showed predicting role of personality traits for gender role attitudes. The significant differences were found on personality traits, gender role attitudes among traditional and non-traditional professionals, and gender as well. In addition, implications and limitations, as well as directions for future research are discussed.

scholarly journals INTENTION TO CONTINUE PARTICIPATING: SYSTEM INTERACTIVITY, VIRTUAL SITES, COMMUNITY COMMITMENT IN ONLINE HIJABS COMMUNITY

2021 ◽  
Vol 19 (1) ◽  
pp. 141-155
Author(s):  
Nindria Untarini ◽  
◽  
Teofilus Teofilus ◽  
Timotius F.C.W Sutrisno ◽  
◽  
...  
Keyword(s):  
Virtual Community ◽  
Structural Equations ◽  
Theory And Practice ◽  
Future Research ◽  
Marketing Theory ◽  
Member Commitment ◽  
Relationship Of ◽  
Intention To Continue ◽  
The Relationship

This study aims to examine system interactivity affecting member commitment and intention to continue participating in the online hijabs community. At the same time, testing how the role of virtual sites in the form of posting in strengthening the relationship (moderate) system interactivity to continue to participate in the online hijabs community. An online hijabs community was researched because the problem observed in the research was relevant to the virtual community. Based on 358 valid responses from students in Surabaya who actively joined the online hijabs community obtained from questionnaires at each university in Surabaya, structural equations modeling (SEM) was used to test the research model. The results show that system interactivity affects commitment to the community, but does not affect the intentions of members to continue their participation in online hijabs communities. Likewise, commitment to the community does not stimulate the intentions of members to remain actively participating in online hijabs communities. Although, an interesting form of posting can strengthen the system’s interactivity relationship of members’ intentions to continue their participation in online communities. Implications for both marketing theory and practice, limitations, and future research on video storytelling in social media are discussed.

scholarly journals Impact of Execution Planning on Agile Project Success with Mediating and Moderating Mechanism

2019 ◽  
Vol 8 (12S) ◽  
pp. 668-672
Keyword(s):  
Information Sharing ◽  
Project Success ◽  
Future Research ◽  
Mediating Role ◽  
Agile Methodology ◽  
Organization Effectiveness ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

The present study investigated the impact of execution planning on agile project success with the mediating role of information sharing and moderating role of organization effectiveness because of the highlighted importance of agile methodology in the project industry due to its interactive customer collaborative approach. For this purpose, data were collected from software industry in Pakistan who utilize agile methodology in their projects. 300 completed questionnaires were received from the distributed and 280 were utilized for data analysis. The results delineated that execution planning has positive and significant relationship with agile project success. Similarly, the results indicated that information sharing mediates the relationship between execution planning and agile project success. Furthermore, the data showed that organization effectiveness moderates the relationship of execution planning and information sharing. Lastly, we conclude with theoretical and practical implications as well as future research directions.

Justice and employee engagement

2015 ◽  
Vol 7 (1) ◽  
pp. 89-103 ◽  
Author(s):  
Manish Gupta ◽  
Yln Kumar
Keyword(s):  
Employee Engagement ◽  
Future Research ◽  
Content Type ◽  
Mediating Role ◽  
Member Exchange ◽  
Challenging Environment ◽  
High Level ◽  
Relationship Of ◽  
The Relationship

Purpose – The purpose of this paper is to examine the mediating role of trust in the relationship of justice and employee engagement (EE) in Indian B-schools. Design/methodology/approach – Multiple regression was carried out on the responses obtained from 320 academics working in different Indian B-schools. Findings – The results showed that vertical trust (VT) partially mediates the procedural justice (PJ) and the EE relationship. Distributive justice, PJ, VT and EE were found to be significantly correlated with each other. Research limitations/implications – A very important implication from the findings is that the research will help the Indian B-schools engage their employees in a better manner and face the challenging environment. Future research can be carried out on finding the mediating effects of leader member exchange on VT-EE relationships with other levels of higher education. Originality/value – The current study empirically proved that a good level of PJ leads to a high level of VT and which ultimately results in engaged academics in Indian B-schools.

scholarly journals Potential Role of Laccases in the Relationship of the Maize Late Wilt Causal Agent, Magnaporthiopsis maydis, and Its Host

2020 ◽  
Vol 6 (2) ◽  
pp. 63
Author(s):  
Ofir Degani ◽  
Yuval Goldblat
Keyword(s):  
Potential Role ◽  
Dry Weight ◽  
Maize Cultivars ◽  
Maize Plants ◽  
Relationship Of ◽  
The Relationship ◽  
Host Tissues ◽  
Adult Plants

Late wilt is a vascular disease of maize (Zea mays L.) caused by the soil-borne and seed-borne fungus Magnaporthiopsis maydis. The pathogen penetrates the roots of maize plants at the seedling stage, grows into the xylem vessels, and gradually spreads upwards. From the flowering stage to the kernel ripening, the fungal hyphae and secreted materials block the water supply in susceptible maize cultivars, leading to rapid dehydration and death. Laccase is an enzyme secreted by fungus for diverse purposes. The M. maydis laccase gene was identified in our laboratory, but under what conditions it is expressed and to what functions remain unknown. In the current study, we tested the influence of plant age and tissue source (roots or leaves) on M. maydis laccase secretion. The results show increasing laccase secretion as corn parts (as ground tissue) were added to the minimal medium (MM). Furthermore, roots stimulated laccase secretion more than leaves, and adult plants enhanced laccase secretion more than young plants. This implies the possibility that the richer lignin tissue of adult plants may cause increased secretion of the enzyme. In vitro pathogenicity assay proved the ability of M. maydis to develop inside detached roots of maize, barley, watermelon, and cotton but not peanut. Testing root powder from those plants in MM revealed a negative correlation between M. maydis growth (expressed as biomass) and laccase secretion. For example, while the addition of maize, barley, or cotton root powder led to increasing fungal dry weight, it also resulted in relatively lower laccase activity. Watermelon and peanut root powder led to opposite responses. These findings suggest a pivotal role of laccase in the ability of M. maydis to exploit and grow on different host tissues. The results encourage further examination and a deeper understanding of the laccase role in these interesting host–pathogen interactions.

scholarly journals Relationship of possible biomarkers with malignancy of thymic tumors: a meta-analysis

2019 ◽  
Author(s):  
Huilan Zeng ◽  
Weilin Yang ◽  
Bo Xu ◽  
Jianyong Zou ◽  
Chunhua Su ◽  
...  
Keyword(s):  
Thymic Carcinoma ◽  
Malignant Tumors ◽  
Meta Analysis ◽  
Stage I ◽  
Stage Iii ◽  
Masaoka Stage ◽  
Degree Of Malignancy ◽  
Relationship Of ◽  
The Relationship

Abstract Introduction Role of biomarkers for promotion of tumor proliferation (BPTPs) and for promotion of apoptosis (BPAs) in thymic malignant tumors is still unclear. The purpose of this study was to evaluate the relationship between BPTPs and/or BPAs and malignancy of thymic malignant tumors. Materials and Methods Studies on thymic malignant tumors and biomarkers were searched in PubMed, ISI Web of Knowledge, and Embase databases, and all statistical analyses were conducted using Review Manager. Results Twelve articles related to biomarkers and thymic malignant tumors were selected and analyzed. A relationship between BPAs and Masaoka stage was demonstrated for four markers, included 138 stage I/II patients and 74 stage III/IV patients, and BPAs were significantly correlated with high Masaoka staging (P = 0.005). We further found a relationship between BPAs and degree of malignancy for four markers, included 176 thymoma patients and 36 thymic carcinoma patients, and BPAs were significantly correlated with thymic carcinoma (P = 0.010). In addition, a relationship between BPTP and Masaoka staging was demonstrated for eight markers, included 374 patients with stage I/II and 282 patients with stage III/IV, and BPTPs were significantly correlated with high Masaoka staging (P < 0.001). We also found BPTPs were significantly correlated with thymic carcinoma (P < 0.001). Conclusion These findings show that high levels of BPTPs or BPAs are more closely related to thymic carcinoma and Masaoka stage III/IV, suggesting that BPTPs and BPAs may play an important role in the occurrence and development of thymic malignant tumors.

scholarly journals The release of an endogenous pyrogen from guinea pig leukocytes in vitro: a new model for investigating the role of lymphocytes in fevers induced by antigen in hosts with delayed hypersensitivity.

1977 ◽  
Vol 145 (5) ◽  
pp. 1288-1298 ◽  
Author(s):  
P Chao ◽  
L Francis ◽  
E Atkins
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Polymorphonuclear Leukocytes ◽  
Delayed Hypersensitivity ◽  
Endogenous Pyrogen ◽  
Phagocytic Cells ◽  
Relationship Of ◽  
The Relationship

Guinea pig periotoneal exudate (PE) cells incubated overnight in vitro with heat-killed Staphylococci released an endogenous pyrogen (EP) that could be assayed by intravenous injection in rabbits. The febrile responses were linearly related to the dosage of EP over an eightfold range. PE cells derived from guinea pigs with delayed hypersensitivity (DH) to bovine gamma globulin (BGG), also released EP when incubated with antigen in vitro. This reaction was specific and did not occur withe PE cells from normal or complete Freund's adjuvant-sensitized guinea pigs. Studies indicated that monos and/or polymorphonuclear leukocytes rather than lymphocytes were the source of EP. However, when incubated with BGG and sufficient dosages of BGG-sensitized lymphocytes, normal PE cells released EP over a 42 h period. These results suggest that antigen stimulates specifically sensitized lymphocytes to release an agent (perhaps a lymphokine) that activates phagocytic cells to release EP. This model offers unique advantages for investigating in vitro the role of the lymphocyte in antigen-induced fever in DH as well as the relationship of this lymphocyte-induced activity to other known biologic activities mediated by antigen stimulated lymphocytes.

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