Serum vitamin D levels in children with newly diagnosed and chronic immune thrombocytopenia

2016 ◽  
Vol 53 ◽  
pp. S67-S69 ◽  
Author(s):  
Srđana Čulić ◽  
Joško Markić ◽  
Davor Petrović ◽  
Paško Konjevoda ◽  
Jasminka Pavelić
Keyword(s):  
Vitamin D ◽  
Immune Thrombocytopenia ◽  
Serum Vitamin ◽  
Newly Diagnosed ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Chronic Immune Thrombocytopenia

Serum Vitamin D Levels in Children with Immune Thrombocytopenia

2020 ◽  
Vol 20 (2) ◽  
pp. 221-226 ◽  
Author(s):  
Giuseppe Lassandro ◽  
Francesco Carriero ◽  
Viviana Palmieri ◽  
Valentina Palladino ◽  
Anna Amoruso ◽  
...  
Keyword(s):  
Vitamin D ◽  
Immune Thrombocytopenia ◽  
Serum Vitamin ◽  
Newly Diagnosed ◽  
Serum Vitamin D ◽  
Chronic Itp ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Newly Diagnosis

Objective: Immune thrombocytopenia (ITP) is an acquired immuno-mediated disorder characterized by thrombocytopenia with an increased risk of bleeding. In recent years 1,25[OH]2D3 has been rediscovered as an immune modulator. We decided to evaluate serum Vitamin D levels in a cohort of children with immune thrombocytopenia in order to discover if Vitamin D concentrations may predict ITP duration. Methods: Thirty children were enrolled in this study (sixteen with chronic ITP and fourteen with newly diagnosed ITP) to assess serum Vitamin D levels. Results:: The results showed that 80% of the enrolled children presented a D hypovitaminosis status. Children with newly diagnosis ITP showed no statistically significantly higher median values of Vitamin D compared to chronic ITP. Conclusions:: This study may suggest that Vitamin D deficiency does not represent a chronicity factor for ITP. However, further studies are needed to understand the role of Vitamin D in ITP pathogenesis.

Prognostic characteristics of 492 newly diagnosed breast cancer patients by serum vitamin D levels.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e12619-e12619 ◽  
Author(s):  
Luke Joseph Peppone ◽  
Mohamedtaki Abdulaziz Tejani ◽  
Karen Michelle Mustian ◽  
Michelle Christine Janelsins ◽  
Charles Stewart Kamen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Patients ◽  
Serum Vitamin ◽  
Newly Diagnosed ◽  
Breast Cancer Patients ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Serum Levels of Vitamin D in Patients with Multiple Myeloma

Folia Medica ◽  
2020 ◽  
Vol 62 (4) ◽  
pp. 730-735
Author(s):  
Vasko Graklanov ◽  
Veselin Popov ◽  
Ralitsa Raycheva
Keyword(s):  
Multiple Myeloma ◽  
Vitamin D ◽  
Serum Vitamin ◽  
Reference Value ◽  
Serum Levels ◽  
Newly Diagnosed ◽  
Serum Vitamin D ◽  
Maximum Value ◽  
Vitamin D Levels ◽  
International Myeloma Working Group

Aim: &#1058;&#1086; investigate the serum levels of vitamin D in newly diagnosed patients with multiple myeloma. Patients and methods: In this study we measured the serum levels of vitamin D in 37 patients (19 women, 18 men) at a median age of 68 years and a diagnosis of MM according to the International Myeloma Working Group (IMWG) criteria. The immunoassay tests used for the quantification of 25 (OH) &ndash; Vitamin D were original ELISA kits Immundiagnostic and the measurement was done before starting the treatment. Results: Serum levels below the optimum (<30 ng/ml) were recorded in all 37 patients. The median value of vitamin D was 4.3&plusmn;6.5 mg/ml, the maximum value measured was 24.7 mg/ml, which is below the lower limit of the reference value for deficiency. Conclusions: In this study, we found extremely low serum vitamin D levels in most of the newly diagnosed MM patients.

STUDY THE SERUM VITAMIN D LEVELS IN PATIENTS OF CHRONIC KIDNEY DISEASE

2021 ◽  
pp. 1-3
Author(s):  
Brahmarshi Das ◽  
Narendranath Hait ◽  
Jayanta Kumar Rout ◽  
Debarshi Jana
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Kidney Diseases ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Newly Diagnosed ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Mean

INTRODUCTION: Chronic Kidney Disease (CKD) is dened as a disease characterized by alterations in either kidney structure or function or both for a minimum of 3 months duration. Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney 1 function over a period of months or years. Early on there are typically no symptoms. Later, leg swelling, feeling tired, vomiting, loss of appetite, or 1 confusion may develop. Complications may include heart disease, high blood pressure, bone disease, or anemia. AIM AND OBJECTIVES: Study of Prevalence of hypovitaminosis D in patients of chronic kidney diseases. Search for commonest etiology of hypovitaminosis D in CKD. MATERIALAND METHOD: A Cross-sectional study on 100 cases of newly diagnosed Chronic Kidney Disease patients and matched control subjects is undertaken to study the prevalence of Vitamin D deciency in CKD population and correlation between their serum 25-OH-vitamin D level. 100 Patients who are newly diagnosed as CKD are selected after proper initial screening at Midnapore Medical College, Paschim Medinipur. RESULT AND ANALYSIS: Our study showed that in non-dialysis Syndrome the mean VitD (mean± s.d.) of patients was 25.6620 ± 8.5476. In dialysis the mean VitD (mean± s.d.) of patients was 10.9476 ± 2.6508. Difference of mean VitD in Dialysis vs Non-Dialysis was statistically signicant (p<0.0001). In eGFR 1 (<15) the mean VitD (mean± s.d.) of patients was 11.1130 ± 2.9562. In eGFR2 (15-30) the mean VitD (mean± s.d.) of patients was 24.0750 ± 8.2995. In eGFR3 (31-45) the mean VitD (mean± s.d.) of patients was 26.8296 ± 7.3646. In eGFR4 (>45) the mean VitD (mean± s.d.) of patients was 36.3167 ± 4.9898. Difference of mean VitDin eGFR was statistically signicant (p<0.0001). SUMMARYAND CONCLUSION: Vitamin-D deciency more pronounced in advanced stages of CKD. Vitamin-D deciency was most prevalent in female gender, younger age group and connective tissue disorder. Vitamin-D deciency was more marked in hemodialysis patients compared to non-dialysis CKD patients.

scholarly journals Vitamin D levels in patients with non-Hodgkin lymphoma/diffuse large B-cell lymphoma, chronic lymphocytic leukemia and multiple myeloma

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052094342
Author(s):  
Vasko Graklanov ◽  
Veselin Popov
Keyword(s):  
Vitamin D ◽  
Cell Lymphoma ◽  
Serum Vitamin ◽  
B Cell Lymphoma ◽  
Lymphocytic Leukemia ◽  
Newly Diagnosed ◽  
Serum Vitamin D ◽  
Non Hodgkin Lymphoma ◽  
Large B Cell Lymphoma ◽  
Vitamin D Levels

Purpose To investigate serum vitamin D levels in patients newly diagnosed with non-Hodgkin lymphoma/diffuse large B-cell lymphoma (NHL-DLBCL), multiple myeloma (MM) and chronic lymphocytic leukemia (CLL). Patients and methods We measured serum levels of vitamin D by ELISA in 103 patients prior to initiation of treatment, of whom 37 were diagnosed with MM, 32 with CLL and 34 with NHL-DLBCL. Results Suboptimal serum vitamin D levels (<30 ng/mL) were observed in all 103 patients. In 14 patients, serum vitamin D levels were between 20 and 30 ng/mL, while all other patients had vitamin D deficiency (<20 ng/mL). Severe vitamin D deficiency (<10 ng/mL) was observed in 32.3% of NHL-DLBCL patients, 28.1% of CLL patients and 81% of MM patients. Conclusion We observed low serum vitamin D levels in the majority of patients newly diagnosed with NHL-DLBCL, CLL and MM.

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Female Sex ◽  
Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

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