scholarly journals Evaluation of Systemic Markers Related To Anemia of Chronic Disease in the Peripheral Blood of Smokers and Non-Smokers with Chronic Periodontitis

2008 ◽  
Vol 02 (02) ◽  
pp. 102-109 ◽  
Author(s):  
Ebru Olgun Erdemir ◽  
Rana Nalcaci ◽  
Osman Caglayan
Keyword(s):  
Chronic Disease ◽  
Cigarette Smoking ◽  
Chronic Periodontitis ◽  
Peripheral Blood ◽  
Clinical Parameters ◽  
Clinical Attachment Loss ◽  
Anemia Of Chronic Disease ◽  
Cell Parameters ◽  
Probing Depth ◽  
Age Range

ABSTRACTObjectives: The aim of this study was to investigate the effect of cigarette smoking on clinical parameters and signs anemia of chronic disease in chronic periodontitis patients.Methods: The study base consisted of 88 patients with chronic periodontitis including 45 volunteer current smokers with age range of 30-69 (45.5±8.5) and 43 volunteer non-smokers with age range of 32-61 years (45.8±7.9). The clinical parameters including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) were recorded and several red blood cell parameters were determined from peripheral blood samples.Results: In smokers, PI, PD and CAL were significantly higher than non-smokers (P<.05). The number of erythrocytes and the levels of hemoglobin, hematocrit and iron were lower in smokers compared to non-smokers (P<.05).Conclusions: In the present study, it is concluded that cigarette smoking may be effective on the signs of anemia of chronic disease in patients with chronic periodontitis. (Eur J Dent 2008;2:102-109)

Optimization of the terms of supportive periodontal therapy using photoactivated disinfection

2019 ◽  
Vol 24 (2) ◽  
pp. 121-126 ◽  
Author(s):  
V. G. Atrushkevich ◽  
L. Yu. Orekhova ◽  
O. O. Yanushevich ◽  
E. Yu. Sokolova ◽  
E. S. Loboda
Keyword(s):  
Chronic Periodontitis ◽  
Adjunctive Treatment ◽  
Control Group ◽  
Clinical Parameters ◽  
Ozone Therapy ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Supportive Periodontal Therapy ◽  
Tannerella Forsythensis ◽  
Observation Period

Relevance: to indentify if periodontal treatment which is presented by photoactivated disinfection (PAD) adjunctively to scaling and root planing (SRP) yield better outcomes than ozone therapy as an adjunct to SRP in periodontitis.Materials and methods: we examined 57 (mean age 49,3 ± 1,02) patients with chronic periodontitis, divided into groups, SRP + PAD, SRP + ozone therapy and SRP alone. Subgingival plaque samples were subjected to DNA extraction and real time PCR amplifcation for detection Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Tannerella forsythensis (Tf), Treponema denticola (Td), Aggregatibacter actinomycetemcomitans (Aa). The amount of periodontopathogens and clinical parameters including plaque index, clinical attachment loss, pocket depth, bleeding on probing were measured at baseline, after 40, 90 and 180 days.Results: the results in groups of PAD+SRP and ozone therapy+SRP showed an improvement in all clinical parameters PI, BOP, PD, CAL and the quantity of Pg, Td and Tf compared to the control group during an observation period.Conclusion: the results showed additional benefts from PAD and ozone therapy as an adjunctive treatment to SRP for patients of chronic periodontitis.

scholarly journals Lymphotoxin-Alpha Gene Polymorphism +252A/G (rs909253, A/G) Is Associated with Susceptibility to Chronic Periodontitis: A Pilot Study

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Daniel Fernando Pereira Vasconcelos ◽  
Marco Antônio Dias da Silva ◽  
Marcelo Rocha Marques ◽  
Rui Barbosa de Brito Júnior ◽  
Any Carolina Cardoso Guimarães Vasconcelos ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Dna Analysis ◽  
Clinical Findings ◽  
Risk Indicator ◽  
Clinical Attachment Loss ◽  
Probing Depth ◽  
Chronic Periodontal Disease ◽  
Length Polymorphisms ◽  
Lymphotoxin Alpha

Background. Periodontal disease leading to clinical findings such as increased periodontal probing depth involves a complex interaction between invading pathogenic microorganisms and the patient's immune system. Lymphotoxin alpha (LT-α) is a potent multifunctional immune modulator that contributes toward susceptibility to immune regulation disorders, including periodontal disease. Objective. In this study, we tested the hypothesis that chronic periodontitis (CP) is associated with polymorphisms of the LT-α gene. Materials and Methods. A total of 126 subjects, 44 healthy subjects, and 82 subjects with CP, were evaluated for periodontal disease by measuring clinical attachment loss and separation. Samples of epithelial cells were obtained for DNA analysis by scraping of the buccal mucosa. The LT-α gene was analyzed by polymerase chain reaction followed by endonuclease digestion with NcoI to analyze restriction fragment length polymorphisms. Results. The LT-α gene (+252A/G) polymorphism was associated with CP. LT-α allele frequencies were significantly different (P=0.0019) between patients with CP and healthy individuals, with an odds ratio of 2.67 for patients with CP with the G allele. Conclusions. These findings suggest the LT-α gene genotype is a risk indicator for susceptibility to chronic periodontal disease in the Brazilian population studied.

scholarly journals Clinical Evaluation of Gutkha chewing and Pattern of Bone Loss in Periodontitis

2014 ◽  
Vol 5 (4) ◽  
pp. 199-203
Author(s):  
Harshal Liladhar Chaudhari ◽  
Nipun Ashok ◽  
Veena Kalburgi ◽  
Haziel Dina Jenifer
Keyword(s):  
Bone Loss ◽  
Clinical Evaluation ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Probing Depth ◽  
Proximal Site ◽  
Almost All ◽  
Age Range ◽  
Maxillary Arch

ABSTRACT Introduction Tobacco in the form of Gutkha is commonly used in India. The present study was done to analyze the extent and pattern of alveolar bone loss (ABL) among gutkha chewers who were having chronic periodontitis. Materials and methods A total of 55 habitual gutkha chewers within the age range of 18 to 35 years with chronic periodontitis, who were otherwise healthy were recruited for the study. Fourteen full mouth intraoral periapical (IOPA) radiographs were taken for each individual (a total of 770 radiographs) with the help of radiovisiography. Kodak dental software was used to analyze and measure the alveolar bone loss at each proximal site and data were computed as percentage alveolar bone loss. Results Almost all the subjects had poor oral hygiene status. Clinical parameters of periodontal examination represented by clinical attachment level, probing depth, gingival bleeding index had positive correlation with frequency and duration of gutkha chewing. The study population had a mean alveolar bone loss of 17%. Mean bone loss was more severe in mandible 18.3% ± 2.6, when compared with maxillary arch 15.7% ± 3.7. Conclusion Maximum bone loss was observed with molars and incisors. Alveolar bone loss was more frequently found in mandibular arch as compared to maxillary arch. How to cite this article Warad S, Chaudhari HL, Ashok N, Kalburgi V, Kalburgi NB, Jenifer HD. Clinical Evaluation of Gutkha chewing and Pattern of Bone Loss in Periodontitis. World J Dent 2014;5(4):199-203.

scholarly journals Effectiveness of the adjunctive use of ozone and chlorhexidine in patients with chronic periodontitis

BDJ Open ◽  
2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Kaveri Kranti Gandhi ◽  
Emil G. Cappetta ◽  
Rajdeep Pavaskar
Keyword(s):  
Chronic Periodontitis ◽  
Gold Standard ◽  
Gingival Index ◽  
Periodontal Pathogens ◽  
Ozone Therapy ◽  
Clinical Attachment Loss ◽  
Probing Depth ◽  
Root Planning ◽  
Scaling And Root Planning

Abstract Background Scaling and root planning (SRP) is the gold standard approach for treatment of chronic periodontitis but used alone it may not be effective in removing periodontal pathogens from sites where access is poor. Objective To evaluate and compare the clinical and microbiological efficacy of ozone and chlorhexidine (CHX) as an adjunct to SRP in patients with chronic periodontitis. Methods Twenty-five patients with generalized moderate to severe chronic periodontitis with presence of at least one site in each quadrant with a probing depth ≥5 mm were recruited. In a split mouth study design, two quadrants were randomly allocated to the SRP and ozone therapy and the remaining two quadrants to SRP and CHX therapy. Plaque index (PI), Gingival index (GI), probing depth (PD), clinical attachment loss (CAL) were assessed. Subgingival plaque samples were obtained for assessment of Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg). Results Both groups demonstrated significant intragroup reduction in PI, GI, PD, CAL, Pg count and Aa count from baseline to 3 months follow-up. There were no significant differences between two groups for any of the parameters. Conclusion Ozonated olive oil can be used as an adjunctive subgingival irrigant in patients with chronic periodontitis.

Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis

2015 ◽  
Vol 16 (11) ◽  
pp. 915-920 ◽  
Author(s):  
Vinayak Mahableshwar Joshi ◽  
Kishore Gajanan Bhat ◽  
Sandeep Suresh Katti ◽  
Manohar Suresh Kugaji ◽  
Preeti Shivaji Ingalgi
Keyword(s):  
Human Cytomegalovirus ◽  
Chronic Periodontitis ◽  
Cross Sectional Study ◽  
Clinical Parameters ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Cross Sectional ◽  
Exact Test ◽  
Healthy Group ◽  
Periodontal Infection

ABSTRACT Objective The identification of new uncultured species and viruses supports the possibility of combination of the herpesvirus- bacterial periodontal infection for periodontitis. The paucity of data and studies with larger sample size in Indian subjects provides an unclear picture of the presence of the herpesvirus in this population. Materials and methods This was a cross-sectional study consisting of 100 each in the healthy group and chronic periodontitis (CP) group. The subgingival plaque was collected and polymerase chain reaction was performed post deoxyribonucleic acid (DNA) extraction by using specific primers for human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV). The data were analyzed using Fisher's exact test, Mann-Whitney U test and Spearman's coefficient correlation. Results Human cytomegalovirus and EBV viruses were significantly higher in the CP group as compare to the healthy group. A higher percentage of those with CMV positive had EBV also positive (28.3%) compared to only 9.1% of CMV negative being EBV positive in the CP group. When both the healthy and CP group in total was compared, there was a significant correlation with all clinical parameters. Conclusion Both the viruses dominated in disease as compared to health were similar to the earlier findings. The CP group had higher pocket depth and clinical attachment loss in the virus positive subjects. These findings could suggest that virus serves as a prelude to the disease and the combination of the two viruses could play a role in the pathogenesis. How to cite this article Joshi VM, Bhat KG, Katti SS, Kugaji MS, Ingalgi PS. Prevalence of Herpesvirus and Correlation with Clinical Parameters in Indian Subjects with Chronic Periodontitis. J Contemp Dent Pract 2015;16(11):915-920.

scholarly journals Arginine and glutamate levels in the gingival crevicular fluid from patients with chronic periodontitis

2008 ◽  
Vol 19 (4) ◽  
pp. 318-322 ◽  
Author(s):  
Narda Téllez ◽  
Natalia Aguilera ◽  
Belkis Quiñónez ◽  
Elizabeth Silva ◽  
Luis Enrique González ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Healthy Controls ◽  
Clinical Attachment Loss ◽  
Measure Concentration ◽  
Periodontal Tissues ◽  
Glutamate Concentration ◽  
Probing Depth ◽  
Crevicular Fluid ◽  
Post Hoc

The objectives of this study were to determine arginine and glutamate levels in the gingival crevicular fluid (GCF) of adult chronic periodontitis patients versus periodontally healthy controls, and to compare two kinds of microdialysis probes: normal and U-shaped probes. The analysis of GCF components was developed to improve the diagnosis of periodontal disease (PD). Proteolysis in the periodontal tissues increases the concentration of amino acids (aa) in the GCF and the levels of these aa may reveal PD features and stages. GCF samples were collected by microdialysis in situ from 5 periodontally affected sites (probing depth >5 mm, clinical attachment loss >3 mm) in 14 adult chronic periodontitis patients and from 14 adult periodontally healthy controls. Capillary zone electrophoresis coupled to laser induced fluorescence detection was used to measure concentration of arginine and glutamate in the GCF. Data were analyzed statistically by ANOVA and Tukey's post-hoc tests (?=0.05). Arginine concentration was increased (p<0.001) and glutamate concentration was decreased (p<0.001) in chronic periodontitis patients as compared to controls. There were no significant differences (p=0.069) between the normal and U-shaped probes. In conclusion, the increase of arginine and decrease of glutamate concentration in GCF were associated to the presence of periodontitis, and might be used as markers to recognize periodontally susceptible subjects as well as to evaluate the treatment course.

PHOTODYNAMIC THERAPY AS AN EFFICIENT ADJUNCT TO NON SURGICAL TREATMENT OF PERIODONTITIS: A CASE SERIES

2021 ◽  
pp. 76-77
Author(s):  
Nisha Jain ◽  
Rudrax Jindal
Keyword(s):  
Photodynamic Therapy ◽  
Surgical Treatment ◽  
Chronic Periodontitis ◽  
Case Series ◽  
Antimicrobial Photodynamic Therapy ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Bleeding On Probing ◽  
Probing Depth ◽  
Non Surgical Treatment

The aim of this case series was to assess the efcacy of antimicrobial photodynamic therapy in the treatment of chronic periodontitis. This case series included two subjects with Presence of pocket depth 6 mm or more with clinical attachment loss(CAL) and bleeding on probing (BOP) in minimum of 1 tooth in atleast two quadrants. After full mouth mechanical debridement (SRP), rst site received no further treatment, whereas, second site was subjected to photodynamic therapy. SRP+PDT group showed signicant improvement in (CAL) and reduction in probing depth as compared to SRP group. Therefore, it can be concluded that Photodynamic therapy has its own advantage as an adjunct to SRP in the non surgical treatment of chronic periodontitis,further research for which may be advocated

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