scholarly journals TO STUDY THE PREVALENCE AND CLINICAL PROFILE OF CHRONIC ATRIAL FIBRILLATION IN HOSPITALIZED PATIENTS

2014 ◽  
Vol 04 (02) ◽  
pp. 017-020
Author(s):  
Dharma Rao V. ◽  
Rajaneesh Reddy M. ◽  
Srikanth K. ◽  
Raj Kumar Prakash B. ◽  
Satya Prasad A. ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Heart Disease ◽  
Care Center ◽  
Tertiary Care ◽  
Chronic Atrial Fibrillation ◽  
Hospitalized Patients ◽  
Clinical Profile ◽  
Female Dominance ◽  
Elderly Age ◽  
Female Ratio

Abstract: Objective: To determine the prevalence of chronic atrial fibrillation (AF) in a tertiary care center and to identify the clinical profile of chronic AF in hospitalized patients. Methods: All patients admitted to Mamata General Hospital in medicine/cardiology wards with chronic AF (persistent and permanent) during the period January 2012 to December 2012 were included into the study. The principal exclusion criteria were new onset AF and acute AF. Results: During the study period, 49 patients were admitted with chronic AF with an average of 45.44 years. A slight female dominance was seen with male: female ratio of 1:1.2. Half of the patients (51%) were below the age 50 years. The elderly age group comprised of only 16.3% of cases. The commonest presenting complaint was dyspnea followed by palpitation. Rheumatic valvular heart disease was seen more commonly in people below the age of 50 years whereas hypertension and ischemic heart disease after 50 years. Heart failure was the commonest condition associated with the chronic AF and was the cause of hospitalization in almost fifty percent of cases Conclusion: Chronic AF is still a cause of concern in India in people below the age of 50 years due to high prevalence of rheumatic fever inspite of advances in the medical field.

scholarly journals Descriptive study of clinical profile and outcome in patients of acute on chronic liver failure, at a tertiary care center in Northern India

2020 ◽  
Vol 7 (11) ◽  
pp. 1687
Author(s):  
Rakesh Kumar ◽  
Vandana Rana ◽  
Varghese Koshy ◽  
Vandana Gangadharan ◽  
George Koshy
Keyword(s):  
Liver Failure ◽  
Care Center ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Chronic Liver Failure ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Common Cause

Background: Acute-on-chronic liver failure (ACLF) is a recently described syndrome that is characterized by abrupt deterioration in patients with chronic liver disease (CLD) and has high short-term mortality. The aim of this study was to describe the clinical profile, causes and outcomes of ACLF at a tertiary care centre in Northern India.Methods: In this descriptive study of 50 consecutive patients, were included, between August 2015 to January 2018, who were admitted and diagnosed as ACLF as defined by APASL. Causes of acute precipitating event and CLD and outcomes were assessed.Occurrence and severity of organ failure was also assessed.Results: 48 (96 %) were males and 2 (4%) were females with male to female ratio was 24:1. The mean age of male and female subjects was similar, 40.7±9.9 years and 39.2±9.4 years respectively. The most common cause of CLD was alcohol in 50% cases and next most common cause was hepato-tropic viruses HBV infection in 20%, HCV in 6% cases and there was unknown cause in 12 % cases. The most common precipitating factor of acute decompensation was alcohol in 50% cases, hepatotropic viruses in 30% cases. Excluded sepsis and GI bleed as precipitating events. The combined mortality at the end of 1-month and 3-months, in our study was 60%. CLIF-SOFA score was found to be the most reliable scoring system to discriminate between survivors and non survivors. Conclusions: Alcohol was the commonest precipitating cause of ACLF. Organ failures (OFs) are independently predictive of mortality.

scholarly journals Surgical Management and Early Outcome of Encephalocele

2021 ◽  
Vol 10 (1) ◽  
pp. 42-45
Author(s):  
Prakash Kafle ◽  
Mohan Raj Sharma ◽  
Sushil Krishna Shilpakar ◽  
Gopal Sedain ◽  
Amit Pradhanang ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Care Center ◽  
Tertiary Care ◽  
Surgical Excision ◽  
Clinical Profile ◽  
Bony Defect ◽  
Female Ratio ◽  
Early Outcome ◽  
Good Outcome ◽  
Occipital Encephalocele

Background: There are limited studies pertaining to management of encephalocele in Nepal. So the present study seems justifiable to bridge the gap in the literature on encephalocele from Nepal on its clinical profile and early outcome. This study aims to characterize the clinical profile, management and outcome of largest series of encephalocele at tertiary care center in Nepal. Materials and Methods: A retrospective analysis of encephalocele, managed surgically at two tertiary care centers between 2015 and 2020, was performed. Results: Total of 25 cases was surgically managed in the present study. The median age of study population was 2.5 months. There were 11 male and 14 female with male to female ratio of 1:1.26. Occipital encephalocele was the most common variant. Lump in the head (n=11) was the commonest clinical presentation followed by hyperteliorism (n=10). One patient presented with cleft lip and one had CSF discharge in a case of occipital encephalocele. Bony defect was the common radiological findings. Excision and repair was the most common mode of surgery leading to good outcome. Mortality rate was 4% with morbidity of 20%. Conclusion: Early surgical excision and tight dural closure with repair of bony defect is the standard treatment with relatively good outcome.

scholarly journals Co-existence of ischemic stroke in Rheumatic and non-rheumatic atrial Fibrillation in a tertiary care teaching hospital of Western Nepal

2017 ◽  
Vol 13 (4) ◽  
pp. 388-391
Author(s):  
Ram Chandra Kafle ◽  
Girija Shankar Jha ◽  
Navaraj Paudel ◽  
Vijay Madhav Alurkar
Keyword(s):  
Atrial Fibrillation ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Rheumatic Heart Disease ◽  
Tertiary Care ◽  
Age Distribution ◽  
Female Ratio ◽  
Common Cause ◽  
Screening Programs ◽  
Rheumatic Heart

Background & Objectives: Stroke is a major public health burden worldwide leading to long-term morbidity and even mortality. Atrial fibrillation (AF) is the most common sustained arrhythmia and is an independent factor to increase risk of ischemic stroke. The risk of stroke further enhanced in rheumatic atrial fibrillation and affects younger population of developing countries.  The study has aimed to find out frequency of co-existence of stroke in AF and secondarily to look for age distribution of stroke and risk factors of AF.Materials & Methods: A retrospective analysis of trans-thoracic echocardiographic records of patients from 1st June 2009 to 31st June 2016 was done. Data were collected in a pre-structured proforma and analyzed.Results: Among 15767 echocardiographies, 577 (3.65%) cases were recorded to have atrial fibrillation. Mean age 65(±15) years ranging from 14 to 100 years. Rheumatic heart disease was the second most common cause of atrial fibrillation after hypertension. The co-existence of ischemic stroke was seen in 87(15.07%) cases with male to female ratio of 1:1.3. The proportion of stroke in rheumatic Atrial fibrillation was 21(18.75%) which was higher than in non-Rheumatic atrial fibrillation 66(14.2%).Conclusion: Rheumatic heart disease is contributing as second most common cause of atrial fibrillation after hypertension, nearly one fourth of total stroke and most common (93%) cause of stroke below the age of 45 years. Preventive strategies aimed at health awareness about rheumatic fever, screening programs at community level, early detection and treatment for hypertension and Rheumatic heart disease can contribute in reduction of stroke burden. 

scholarly journals STUDY OF CLINICAL PROFILE OF WILSON DISEASE IN A TERTIARY CARE CENTER

2020 ◽  
pp. 1-2
Author(s):  
M S Revathy ◽  
Jacob Joseph ◽  
Chitra S ◽  
Sathya G
Keyword(s):  
Early Diagnosis ◽  
Wilson Disease ◽  
Large Scale ◽  
Care Center ◽  
Tertiary Care ◽  
Young Patients ◽  
Clinical Manifestations ◽  
Clinical Profile ◽  
Female Ratio ◽  
Family Screening

Introduction and Aim: Wilson disease is one of the common metabolic liver diseases of the liver due to inborn error of copper metabolism with varied clinical manifestations. We conducted this study to analyze clinical profile of this disease which will help in early diagnosis and management. Materials and Methods: The study was conducted in the Department of Medical Gastroenterology, Govt. Stanley medical college Chennai, from October 2017 to December 2018. 24 Patients diagnosed to have Wilson disease were taken into the study. Wilson disease was diagnosed based on modified Leipzig score. Patients were analysed based on their clinical features at the time of presentation. Results: Majority of the patients were in the age group 15-30 years (56%). Male to female ratio was 15:9. Majority of the patients presented with hepatic manifestations (54%), jaundice was found in 50% patients and 41% patients had ascites. 16% patients had neurologic manifestations and 12.5% patients had both hepato-neurologic features. 16% patients were presymptomatic and was diagnosed on family screening. KF ring was present in 66% patients. 58% of patients were born out of consanguineous marriage. Conclusion: Consanguinity plays an important role in high frequency of disease. Family screening is important for early diagnosis. Hepatic manifestations were found to be more common. Wide variety of clinical presentations emphasize the high index of clinical suspicion especially in young patients with hepatic manifestations. Further large scale follow up studies warranted in view of high degree of consanguinity in India.

scholarly journals A cross sectional study of clinical profile of deaf mute children at tertiary care center

2017 ◽  
Vol 3 (4) ◽  
pp. 826 ◽  
Author(s):  
Apurva Pawde ◽  
Rajeshree Chaurpagar ◽  
Sumit Aggarwal ◽  
Arpana Agrawal ◽  
Sandeep Dabhekar
Keyword(s):  
Hearing Loss ◽  
Cognitive Skills ◽  
Care Center ◽  
Tertiary Care ◽  
Delayed Diagnosis ◽  
Cross Sectional Study ◽  
Branchial Arch ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Female Ratio

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Hearing is necessary to learn language, speech and to develop cognitive skills. Hearing helps in developing child to learn, recognize sounds, identify objects, events and internalize concepts. Effects of hearing loss on the development of child’s ability to learn, to communicate and to socialize can be devastating. The study is planned with the aim to study clinical profile of deaf mute children and to identify ‘socio-demographic’ and ‘health’ profile of deaf mute children. This study shows distribution of various socio-demographic factors in deaf mute children and to study their clinical profile. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The present cross sectional descriptive study was conducted at OPD of ENT department, Government Medical College and Hospital, Akola, Maharashtra. Study was carried out for a period of two months, it’s included Deaf mute children from 2-12 years of age. 50 subjects were reported over the study of 2 months. For data collection demographic parameters, complete birth history including prenatal, perinatal and postnatal history was noted. Thorough clinical examination was carried out with special attention to branchial arch system.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">There were 70% males compared to 30% females. Male: female ratio was 2.33: 1. Pneumonia (10%) and hyperbilirubinemia (10%) was the commonest health problem. In the study deafness were attributed to 38% genetic causes, 28% Non-genetic and idiopathic in 34% of children. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The age at detection of hearing loss is 0-2 yrs age at which if rehabilitation is done can benefit the child to the maximum. Delayed diagnosis of hearing loss can be explained on basis of community practices of neglecting delayed speech, lack of social awareness and partly due to absence of any active health surveillance in this aspect. Multistep protocol for hearing assessment and parental awareness about facilities of rehabilitation and accessibility of services should be emphasized.</span></p>

scholarly journals Clinical profile of thyrotoxicosis and related cardiovascular morbidities among patients attending endocrine outpatient department in a tertiary care centre

2019 ◽  
Vol 7 (10) ◽  
pp. 3666
Author(s):  
Harshwardhan V. Khandait ◽  
Sunil G. Ambulkar ◽  
Parimal S. Tayde
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Tachycardia ◽  
Complete Blood Count ◽  
Care Center ◽  
Tertiary Care ◽  
Central India ◽  
Clinical Profile ◽  
Thyroid Disorders ◽  
Tertiary Care Centre ◽  
Cross Sectional

Background: Thyroid disorders are common in India. Symptoms and signs of thyrotoxicosis are nonspecific. Graves disease is an autoimmune condition and is the most common cause of thyrotoxicosis. Cardiovascular system is frequently affected in thyroid disorders but there is not much data on prevalence of thyrotoxicosis and related cardiovascular morbidities in central India. Objectives of study the clinical profile of patients with thyrotoxicosis and outline the related cardiovascular manifestations in a tertiary care center. Design-over a period of nine months a descriptive cross sectional study was conducted in a tertiary health care center.Methods: A total of 150 patients with thyrotoxicosis were studied. Patients with known diagnosis of thyrotoxicosis and newly diagnosed cases were included. The participants were investigated for thyroid profile, Electrocardiogram, Complete blood count, serum electrolytes and kidney function test.Results: Out of 150 patients of thyrotoxicosis, 87 (58 %) were diagnosed with Graves’s disease. Hypertension was observed in 78 (52 %) of participants. Atrial fibrillation was found in 18 (12%) and sinus tachycardia in 53 (35.33 %) of the participants.Conclusion: Grave’s disease is the commonest cause of thyrotoxicosis. Hypertension, sinus tachycardia and Atrial Fibrillation are the common cardiovascular diseases observed to be associated with thyrotoxicosis.

scholarly journals Clinicomicrobiological profile of infective endocarditis in a tertiary care center of Nepal

2013 ◽  
Vol 8 (4) ◽  
pp. 34-41
Author(s):  
M Ghimire ◽  
P Karki ◽  
B Khanal ◽  
P Acharya ◽  
SK Sharma ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Heart Disease ◽  
Infective Endocarditis ◽  
Care Center ◽  
Tertiary Care ◽  
Health Sciences ◽  
Cross Sectional ◽  
Acinetobacter Species ◽  
Female Ratio ◽  
History Of

Background Infective endocarditis is a common problem and data regarding its clinical and microbiological pattern from developing countries are sparse. We studied clinical features and the microbiological pathogens in patients with Infective Endocarditis in our Hospital. Objective To study the clinical profile and microbiological pathogens involved in patients with Infective Endocarditis, admitted under Department of Internal Medicine of B.P Koirala Institute of Health Sciences. Materials and methods A total of 54 patients with history of fever and underlying heart disease were studied. It was a hospital based cross sectional descriptive study done in patients with infective endocarditis presented to us from March 2007 to February 2008 in B.P Koirala Institute of Health Sciences. Results Out of 54 patients, 11 (20.4%) had Dukes definite IE. The male: female ratio was 1.2:1. The mean age of the study group was 27.3 years (range=16-55). In IE group, fever was present in 100% cases (n=11) as it was the inclusion criteria of the study, followed by SOB 81.8% (n=9). History of antibiotic therapy prior to the presentation was present in 36.7 % (n=4) patients. Pallor was the most common sign 63.6% (n=7). Splenomegaly was seen in 18.2% (n=2). Anaemia (Hb<10gm %) in 36.4% (n=4) and microscopic haematuria in 72.3% (n=8) cases. Blood culture positivity was seen in 36.4 %. The most common pathogens were Staphylococcus aureus in 27.3% (n=3) and Acinetobacter species in 9.1% (n=1). Conclusion In our study we found that the clinical spectrum of IE was different from the west in that the majority of patients being young in our study. However, RHD still is the commonest underlying heart disease and Staphylococcus aureus being the commonest isolate. Journal of College of Medical Sciences-Nepal, 2012, Vol-8, No-4, 34-41 DOI: http://dx.doi.org/10.3126/jcmsn.v8i4.8698  

scholarly journals Head Injury in Nepal: An Institutional Based Prospective Study on Clinical Profile, Management and Early Outcome of Traumatic Brain Injury in Eastern Part of Nepal

2019 ◽  
Vol 4 (2) ◽  
pp. 750-754
Author(s):  
Prakash Kafle ◽  
Babita Khanal ◽  
Dipak Kumar Yadav ◽  
Deepak Poudel ◽  
Tejendra Karki ◽  
...  
Keyword(s):  
Brain Injuries ◽  
Road Traffic ◽  
Care Center ◽  
Tertiary Care ◽  
College Teaching ◽  
Clinical Profile ◽  
Tertiary Care Center ◽  
Cross Sectional ◽  
Female Ratio ◽  
Early Outcome

Introduction: Traumatic brain injuries (TBI) are among the worst consequences and are the major causes of death and disability worldwide. It is considered as silent epidemics affecting individuals of all the ages and one of the major burden of neorological disease. Hence, TBIs are often overlooked and are sometimes called “the neglected disease of modern society”. Presenting GCS is the best predictor of outcome. Objective: The present study aims to portray the epidemiology, clinical profile, its management, early outcome and to evaluate the outcome predictors in a tertiary care center in eastern part of Nepal. Methodology: This is a prospective cross-sectional study conducted at the Department of Neurosurgery, Nobel Medical College Teaching Hospital, Biratnagar, Nepal over the period of 1 year (October, 2016 - December 2017). The primary objective of this study was to review the etiology, clinical profile and early outcome of patients with TBI. Results: During the study period, 1056 patients with head injuries were studied. Of these 202 cases required surgical intervention and 32 were excluded. Mean age of the study population was 38.7 years with the male to female ratio of 3.49:1. Road traffic accident was the most common cause of TBI (76%). Overall mortality rate was 11.17%. Unfavorable GOS at discharge was 43.5% and 26.1% at three months follow-up. Conclusion: TBI continues to be a significant burden of neurosurgical care in major neurosurgical centers in Nepal. This study contributes data on the etiology and clinical profile of patients with TBI from tertiary care center of Nepal.

Clinical profile and outcome of critically sick patients of dengue, admitted in PICU of a tertiary care center

2016 ◽  
Vol 3 (4) ◽  
pp. 20
Author(s):  
Vikram Bhaskar ◽  
Jeedan Hemrom ◽  
Virender Kumar ◽  
Sandeep Kumar ◽  
Viswas Chhapola
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Tertiary Care Center

GASTRIC CANCER: A 5 YEAR RETROSPECTIVE ANALYSIS OF CLINICAL, PATHOLOGICAL AND TREATMENT ASPECTS FROM A TERTIARY CARE CENTER IN SOUTH INDIA.

2021 ◽  
pp. 129-132
Author(s):  
B. Ramkumar ◽  
J. Kannan ◽  
Ingersal. N ◽  
Srigopal mohanty ◽  
Amit saklani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
South India ◽  
Care Center ◽  
Tertiary Care ◽  
Tumor Location ◽  
Advanced Stage ◽  
Tertiary Care Center ◽  
Nodal Disease ◽  
Female Ratio

Context: Gastric cancer(GC) is fth most common cancer worldwide. Mostly presents with advanced stage and poor overall survival. Methods: Retrospective study on clinical, pathological, pattern of distant metastasis(DM) , treatment aspect of GC treated between January 2014 to December 2018 in a tertiary care center in south India. Statistical analysis : Chi square test and multivariate analysis (MVA) were used for analysis. P <0.05 was considered signicant. Results: Median age at diagnosis is 57 years. Higher male : female ratio. Most common presentation was abdominal pain followed vomiting. Malignant Gastric outlet obstruction(MGOO) was present in 22.7%. Histologically , all patients had adenocarcinoma with predominantly moderate differentiation (51.1%). Liver (19.1%)was most common site of metastasis . Curative surgery was done in 35.5% of patients. D2 lymph node dissection was performed in 12.4% of patient. Patients were given perioperative /preoperative/ adjuvant / palliative chemotherapy. MVA revealed history of tobacco use, body of stomach tumor location, nodal disease were risk factors for DM. Conclusion : The present analysis revealed use of tobacco, alcohol intake were main risk factors for GC. Most of the patients present in advanced stage , so prevention by avoiding risk factors and early detection by signs , symptoms and endoscopy are necessary. Use of tobacco,site of tumor location, nodal disease were factors associated with DM. Aggressive management with both surgery and chemotherapy is warranted for locally advanced disease.

Sign in / Sign up

Export Citation Format

Share Document