scholarly journals Assessment of Hearing Loss in Patients Receiving Chemoradiotherapy in Adjuvant Setting for Head and Neck Malignancy

2020 ◽  
Vol 3 (01) ◽  
pp. 16-22
Author(s):  
Vani Krishana Gupta ◽  
Mahesh Bhat ◽  
Vinay Vaidyanathan Rao ◽  
Vishak Surendra
Keyword(s):  
Hearing Loss ◽  
Head And Neck ◽  
Hearing Aids ◽  
Otitis Media With Effusion ◽  
Care Center ◽  
Tertiary Care ◽  
Intensity Modulated Radiotherapy ◽  
Pure Tone Audiometry ◽  
Average Dose ◽  
Head And Neck Malignancies

Abstract Introduction The aim of the study is to assess the hearing loss in patients who receive chemoradiation (chemoradiotherapy or CTRT) for head and neck malignancies. Materials and Methods Prospective study was conducted in the Department of ENT of a tertiary care center from September 2013 to August 2014. Forty patients suffering from head and neck malignancies (histologically proven) were included in the study. Patients with pre-existing hearing loss were excluded. All patients received radiotherapy dose of 66 to 70 Gy given as 2 Gy/d, 5 d/wk and chemotherapy dose of cisplatin 35 mg/m2 once a week for 6 weeks. Hearing was assessed by pure tone audiometry (PTA) and impedance audiometry conducted at regular intervals. Mcnemars chi-square test was used to compare the impedance and paired t-test and Pearson’s correlation were used to compare PTA at various stages. Results Predominantly male patients (28) falling in the age group of 40 to 60 years, suffered from various head and neck cancer, most common being oropharynx (14). Twenty patients developed sensorineural hearing loss (SNHL)—11(55%) had mild, seven (35%) had moderate, and two (10%) had severe grade of SNHL. Majority of these patients, 12 (60%) started developing SNHL mid-therapy, five (25%) at the completion of therapy and three (15%) 3 months post-therapy. Hearing loss was found to be more with two-dimensional radiotherapy (2DRT) and three-dimensional radiotherapy (3DRT) than with intensity-modulated radiotherapy (IMRT) as assessed by serial PTA. The average dose of radiation to right and left ears, respectively were 27.10 and 24.66 Gy. The incidence of otitis media with effusion increased during the treatment accounting for the conductive hearing loss irrespective of the modality of radiation used. Conclusion CTRT causes significant hearing loss in patients suffering from head and neck malignancies leading to further increase in the morbidity. Screening audiological assessment would be helpful to know the pretherapy status of the ear. Using newer modalities like IMRT can reduce hearing loss. Regular audiological screening can catch it at its onset and help in early use of hearing aids.

scholarly journals Primary Care Approach to Hearing Loss: The Hidden Disability

2005 ◽  
Vol 84 (1) ◽  
pp. 26-44 ◽  
Author(s):  
Seth M. Cohen ◽  
Robert F. Labadie ◽  
David S. Haynes
Keyword(s):  
Primary Care ◽  
Hearing Loss ◽  
Cochlear Implants ◽  
Hearing Aids ◽  
Primary Care Physicians ◽  
Care Center ◽  
Tertiary Care ◽  
Local Resources ◽  
Academic Center ◽  
Care Approach

We report the results of a survey designed to investigate audiologic referral patterns of primary care physicians and, more specifically, their referral of patients for hearing aids and cochlear implants. Three hundred internal medicine and family medicine physicians were identified from a referral basin of a tertiary care center and chosen randomly to be faxed questionnaires concerning their views about patients with hearing loss, hearing loss screening and referral practices, and availability of local resources. Of the 260 physicians who received a questionnaire, 85 (32.7%) responded. Of their communities (60% of which had populations of fewer than 50,000), 82.4% had an otolaryngologist and 40% had access to an academic center. Although 97.6% of the responding physicians indicated that hearing loss affected patients’ quality of life, only 60% assessed patients for hearing loss. “Lack of time” and “more pressing issues” were the most common reasons given for not evaluating patients for hearing loss. Although 76 physicians (89.4%) said they were aware of cochlear implants, only 22 (25.9%) had referred patients for implant evaluation. Lack of referral most commonly resulted from uncertainties about “where to refer” and “which patients were potential candidates.” The results of this survey suggest that a large percentage of primary care physicians do not routinely test for hearing impairment in adults.

scholarly journals Prevalence of hearing impairment in patients with diabetes mellitus at tertiary care center of Nepal

2021 ◽  
Vol 8 (2) ◽  
pp. 60-63
Author(s):  
Neeti Bhat ◽  
Narayan Bahadur Mahotra ◽  
Lava Shrestha ◽  
Tirtha Man Shrestha ◽  
Prashant Tripathi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hearing Loss ◽  
Hearing Impairment ◽  
Care Center ◽  
Tertiary Care ◽  
Hearing Threshold ◽  
Pure Tone Audiometry ◽  
University Teaching ◽  
Public Health Issue ◽  
Diabetic Patients

Background: Diabetes mellitus is a chronic, systemic and metabolic disorder known to affect almost every organ due to its unequivocal complications. The auditory organ is often affected but usually ignored complications of diabetes mellitus. With the rise in the prevalence of diabetes mellitus and hearing impairment in developing countries, it becomes a crucial public health issue if both of them are found to be associated. Objective: To find the prevalence of hearing impairment in diabetic patients. Materials and Methods: This was a cross-sectional study conducted at the Department of Clinical Physiology in collaboration with the Department of General Practice and Emergency Medicine and the Department of Otorhinolaryngology- Head and Neck Surgery, Tribhuvan University Teaching Hospital. After applying exclusion criteria, 55 subjects were recruited for the study. Pure Tone Audiometry, a non-invasive test was used to assess hearing threshold in this study. Audiogram findings of diabetics were then analyzed. Results: Outcomes of the tests revealed that 17 (30%) of subjects with diabetes mellitus had hearing loss, out of which 13 had mild hearing loss. A significantly positive correlation was found between age and hearing threshold at every frequency. Higher frequencies were found to be more affected. The best cut-off age for onset of hearing loss in diabetics was found to be 51.50 years. Conclusion: Current study suggests a 30% prevalence of hearing loss in diabetes mellitus. We observed hearing loss more among the elderly at higher frequencies

AGE-RELATED ISSUES OF THE QUALITY OF LIFE IN HEARING IMPAIRED PATIENTS

2021 ◽  
pp. 885-892
Author(s):  
Л. Е. Голованова ◽  
Е. А. Огородникова ◽  
Е. С. Лаптева ◽  
М. Ю. Бобошко
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Hearing Aids ◽  
Pure Tone Audiometry ◽  
Hearing Impaired ◽  
Hearing Disorders ◽  
Age Related ◽  
Sf 36 ◽  
Significant Difference

Целью исследования было изучение качества жизни лиц с нарушениями слуха в разных возрастных группах. Обследованы 100 пациентов, обратившихся в городской сурдологический центр для взрослых в связи с нарушением слуха: 50 человек - 34-59 лет, 50 - 60 лет и старше, из которых 32 человека были пожилого возраста (60-74 года)и 18 - старческого (75-86 лет). Степень тугоухости оценивали на основании результатов тональной пороговой аудиометрии. Для исследования качества жизни все пациенты заполняли общий опросник MOS SF-36, отражающий физический и психологический компоненты здоровья, а также специальный опросник HHIА(E)-S для лиц с нарушениями слуха. Установлено, что шкала HHIА(E)-S демонстрирует высокую корреляцию со степенью тугоухости у пациентов моложе 60 лет ( R =0,98; достоверность различий на уровне p <0,05), которая снижается у пациентов 60 лет и старше ( R =0,94; различия в оценках при разной степени тугоухости недостоверны). Значительные трудности в старшей возрастной группе могут быть связаны с тем, что людям пожилого и, особенно, старческого возраста сложно пользоваться слуховыми аппаратами (или они для них неэффективны) и оценивать свои затруднения по шкалам опросника. Целесообразно использовать шкалу HHIА(Е)-S в качестве скринингового инструмента для раннего выявления тугоухости, направления пациентов к сурдологу и своевременного слухопротезирования. The aim of the research was to study the quality of life in hearing impaired patients of different age. 100 patients referred to the city audiology centre because of their hearing disorders were examined: 50 patients from 34 to 59 years old and 50 patients from 60 years and older, from which 32 patients were of older age (60 to 74 years old) and 18 of oldest age (75 to 86 years old). A degree of hearing loss was assessed according to results of pure tone audiometry. To study the quality of life all patients filled in the questionnaire MOS SF-36, which evaluates physical and psychological components of health, and the questionnaire HHIA(E)-S, designed specifically for patients with hearing disorders. The HHIA(E)-S scale was found to show high correlation with hearing loss degree in patients younger than 60 years old ( R =0,98 with statistically significant difference, p <0,05), with decreasing correlation in patients from 60 years and older ( R =0,98; no significant difference while assessing various hearing loss degrees). Considerable difficulties in this age group may be explained by the fact, that older and especially oldest patients have a challenge with hearing aids usage (or they are of low efficiency for them) and with assessing theirs difficulties on the questionnaire scales. The HHIA(E)-S scale is useful as a screening tool for early detection of hearing loss, referral of patients to an audiologist and prompt hearing aid fitting.

scholarly journals A study on chronic otitis media in tertiary care center

2018 ◽  
Vol 4 (2) ◽  
pp. 455
Author(s):  
Leena Rajam K. ◽  
Vikram V. J. ◽  
Priyanka C. ◽  
Indumathi R.
Keyword(s):  
Hearing Loss ◽  
Temporal Bone ◽  
Otitis Media ◽  
Care Center ◽  
Tertiary Care ◽  
Disease Process ◽  
Chronic Otitis Media ◽  
Common Finding ◽  
Duration Of Symptoms ◽  
Female Patients

<p class="abstract"><strong>Background:</strong> Chronic otitis media (COM) is a serious healthcare concern worldwide, because of the distress and economic burden to the patient and their family. Temporal bone pneumatization plays an important role in etiology, behaviour, course and outcome of COM. Pneumatisation gets poorer with growing chronicity of the disease<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted between March 2015-March 2017 on female patients visiting with COM, at ENT department Kasturba Gandhi Hospital, Madras Medical College. The records were analysed of the age, duration of symptoms, associated complaints, pure tone audiogram, computerised tomography of temporal bone, mastoid surgery done according to the disease process affecting the ear<span lang="EN-IN">.  </span></p><p class="abstract"><strong>Results:</strong> 35 female COM patients were analysed, most common age group is between 31-40 years in 14 patients. There hearing loss was mild category in 27. There were 27 cases of mucosal type of chronic otitis media and 8 cases of squamous type. The CT scan with sclerosis of mastoid was the common finding<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> In exclusive study on female patients with COM, the mucosal type of COM is common with mild hearing loss and sclerosed mastoid indicating the chronicity<span lang="EN-IN">.</span></p><p class="abstract"> </p>

Head and Neck Cancer—A Clinicopathological Study in a Tertiary Care Center

2008 ◽  
Vol 100 (6) ◽  
pp. 690-697 ◽  
Author(s):  
Bukola F Adeyemi ◽  
Lola V Adekunle ◽  
Bamidele M Kolude ◽  
Effiong E.U. Akang ◽  
Jonathan O. Lawoyin
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Clinicopathological Study

Exposure of weak magnetic fields on auditory nerve of patients with moderate to severe sensorineural hearing loss

2021 ◽  
Vol 20 (5) ◽  
pp. 63-67
Author(s):  
S. V. Surma ◽  
◽  
D. S. Klyachko ◽  
B. F. Shchegolev ◽  
E. A. Ogorodnikova ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Magnetic Fields ◽  
Sensorineural Hearing Loss ◽  
Hearing Aids ◽  
Auditory Nerve ◽  
Health Hazard ◽  
Sensorineural Deafness ◽  
Pure Tone Audiometry ◽  
Sensorineural Hearing ◽  
Alternative Methods

The article shows that one of the alternative methods of treating moderate to severe sensorineural hearing loss can be the use of an external weak magnetic field. The proposed method is based on the coincidence of the effects caused by the exposure of an external electromagnetic field of certain parameters on the auditory nerve, and natural acoustic exposure. The similarity of reaction allows using of external magnetic fields as an artificial stimulator of the auditory system’s neural part. Induction of applied magnetic fields does not exceed 300 µT, which means that under the current legislation such fields are classified as posing no health hazard. This method was tested at Saint Petersburg Research Institute of Ear, Throat, Nose, and Speech based on relevant Ethics Committee approval and complied with informed consent standards of volunteers. 15 patients aged 18 to 45 with III and IV levels of sensorineural deafness without concomitant pathologies were tested. Threshold pure-tone audiometry was performed on each patient at 500, 1000, 2000, 3000, and 4000 Hz before and after the procedure. The results of the experiments showed that electromagnetic stimulation of auditory neurons allows increasing hearing sensitivity. The proposed procedure may not yield a tangible result in patients with auditory deprivation. Patients with hearing aids showed the most significant results. At the same time, the measurements have shown that the sound thresholds among them became 10 dB lower on the average. The non-invasiveness of the exposure provided additional comfort for the patient.

scholarly journals Hearing Rehabilitation through Bone-Conducted Sound Stimulation: Preliminary Results

2018 ◽  
Vol 23 (01) ◽  
pp. 012-017 ◽  
Author(s):  
Fayez Bahmad Jr ◽  
Carolina Cardoso ◽  
Fernanda Caldas ◽  
Monique Barreto ◽  
Anacléia Hilgenberg ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Speech Perception ◽  
Hearing Aids ◽  
Subcutaneous Tissue ◽  
Bone Conduction ◽  
Free Field ◽  
Pure Tone Audiometry ◽  
Skin Impedance ◽  
Significant Difference ◽  
Before And After

Introduction The bone-anchored hearing aid (BAHA) is a bone conduction system that transmits the sound directly to the inner ear by surpassing the skin impedance and the subcutaneous tissue. It is indicated for patients with mixed, conductive and unilateral sensorineural hearing loss who did not benefit from conventional hearing aids (HAs). Although the benefits from BAHA are well demonstrated internationally, this field still lacks studies in Brazil. Objective To assess the auditory rehabilitation process in BAHA users through audiological, speech perception and tinnitus aspects. Methods Individuals with hearing loss were assessed before and after the implantation. The participants were subjected to pure tone audiometry in free field, functional gain audiometry, speech perception tests, tinnitus handicap inventory (THI) in open format, and to the visual analog scale (VAS). Results It was found that the participants benefited from the use of BAHA. The difference in the performance of the participants before and after the BAHA surgery was significant in terms of hearing acuity. There was no statistically significant difference in the speech perception tests. The tinnitus assessment showed that 80% of the participants scored slight tinnitus severity in THI after using a BAHA. Eighty percent of the participants classified their tinnitus as absent to mild in the VAS after the surgery. Conclusion Based on the results of the current study, we can conclude that the participants improved both the auditory perception and the tinnitus handicap.

Outcomes after Application of Active Bone Conducting Implants

2019 ◽  
Vol 24 (4) ◽  
pp. 197-205 ◽  
Author(s):  
Eleonor Koro ◽  
Mimmi Werner
Keyword(s):  
Hearing Aids ◽  
Pure Tone ◽  
Care Center ◽  
Pure Tone Audiometry ◽  
Sound Field ◽  
Hearing Gain ◽  
Mixed Hearing Loss ◽  
Glasgow Benefit Inventory ◽  
The Mean ◽  
Single Sided Deafness

Background: A bone conducting implant is a treatment option for individuals with conductive or mixed hearing loss (CHL, MHL) who do not tolerate regular hearing aids, and for individuals with single-sided deafness (SSD). An active bone conducting implant (ABCI) was introduced in 2012 with indication in CHL, MHL, and SSD, and it is still the only ABCI available. With complete implantation of the active transducer and consequent intact skin, a decrease in infections, skin overgrowth, and implant losses, all common disadvantages with earlier passive bone conducting implants, could be expected. Our Ear, Nose and Throat Department, a secondary care center for otosurgery that covers a population of approximately 365,000 inhabitants, was approved to implant ABCIs in 2012. Objectives: Our aim was to conduct an evaluation of audiological and subjective outcomes after ABCIs. Method: A cohort study with retrospective and prospective data collection was performed.The first 20 consecutive patients operated with an ABCI were asked for informed consent. The main outcome measures werepure tone and speech audiometry and the Glasgow Benefit Inventory (GBI). Results: Seventeen patients accepted to participate and 15 were able to complete all parts. Six patients had CHL or MHL. In this group the pure tone audiometry tests are comparable with an average functional hearing gain of 29.8 dB HL. With bilateral hearing, the mean Word Recognition Score (WRS) in noise was 35.7% unaided and 62.7% aided. Ten patients had the indication SSD. With the hearing ear blocked, the pure tone average was >101 dB HL, compared to 29.3 dB HL in sound field aided. With bilateral hearing, the mean WRS in noise was 59.7% unaided and 72.8% aided. The mean of the total GBI score was 42.1 in the group with CHL or MHL and 20.6 in the group with SSD. Conclusions: The patients benefit from their implants in terms of quality of life, and there is a substantial hearing gain from the implant for patients with conductive or MHL. Patients with SSD benefit less from the implant than other diagnoses but the positive outcomes are comparable to other options for this group.

Risk Factors for Hearing Loss in Patients Treated With Intensity-Modulated Radiotherapy for Head-and-Neck Tumors

2009 ◽  
Vol 74 (2) ◽  
pp. 490-496 ◽  
Author(s):  
Charlotte L. Zuur ◽  
Yvonne J. Simis ◽  
Emmy A. Lamers ◽  
Augustinus A. Hart ◽  
Wouter A. Dreschler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Head And Neck ◽  
Intensity Modulated Radiotherapy ◽  
Head And Neck Tumors ◽  
Intensity Modulated ◽  
Neck Tumors

MicroRNA Expression Profiling of Cutaneous Squamous Cell Carcinomas Arising in Different Sites

2020 ◽  
Vol 163 (3) ◽  
pp. 538-545
Author(s):  
Alexander N. Rock ◽  
Mason D. Fisher ◽  
Gwenyth Amborski ◽  
Dawn C. Allain ◽  
Victoria Klee ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Mirna Expression ◽  
Statistical Significance ◽  
Care Center ◽  
Normal Skin ◽  
Tertiary Care ◽  
Tissue Samples ◽  
Qrt Pcr ◽  
Candidate Mirnas

Objective To examine the microRNA (miRNA) expression profile of cutaneous squamous cell carcinoma (cSCC) tumors from aggressive head and neck locations compared with nonaggressive anatomic sites and normal controls. Study Design Retrospective analysis of miRNA expression. Setting Tertiary care center. Subjects and Methods Tissue samples were collected from 3 anatomic regions: aggressive head and neck sites (ie, ears/lip), nonaggressive locations (ie, extremities/trunk), and adjacent normal skin. RNA was isolated from tissue cores of 45 samples (18 aggressive sites, 15 nonaggressive sites, and 12 normal-adjacent skin). miRNA expression analysis was completed for approximately 800 miRNAs using the NanoString nCounter panel. Five candidate miRNAs were selected for validation. Quantitative real-time polymerase chain reaction (qRT-PCR) was performed on the original samples plus 30 additional tissue samples (7 aggressive sites, 14 nonaggressive sites, and 9 normal-adjacent skin). Results Five candidate miRNAs with significant differences in miRNA expression ( P < 0 ≤ .001) from discovery samples were selected: miR-21, miR-31, let-7g, miR-93, and miR-22. Relative expression for these miRNAs using qRT-PCR in the new sample set did not reveal any significant differences using 1-way analysis of variance. When sets were combined, miR-21 showed increased expression in aggressive tumors relative to nonaggressive tumors ( P = .009), but no others reached statistical significance. Conclusion cSCC behaves more aggressively when originating from specific anatomical subsites of the head and neck. Of 5 miRNAs evaluated, only miR-21 showed significantly higher expression in tumors from aggressive sites relative to nonaggressive sites. Larger sample sizes are needed to evaluate other miRNAs.

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