Helicobacter pylori siedelt gerne auf Mandel-Gewebe

2017 ◽  
Vol 96 (12) ◽  
pp. 822-823
Author(s):  
Kai J. Lorenz
Keyword(s):  
Helicobacter Pylori ◽  
Laryngopharyngeal Reflux ◽  
Chronic Tonsillitis ◽  
Tonsillar Tissue ◽  
H Pylori

Siupsinskiene N et al. Helicobacter pylori in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux. J Laryngol Otol 2017; 131: 549–55 Wie häufig finden sich Helicobacter pylori Infektionen in den Gaumenmandeln und welcher Zusammenhang besteht zwischen H. pylori, den soziodemografischen Patientendaten und dem laryngopharyngealen Reflux?

Helicobacter pylori in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux

2017 ◽  
Vol 131 (6) ◽  
pp. 549-556 ◽  
Author(s):  
N Siupsinskiene ◽  
I Katutiene ◽  
V Jonikiene ◽  
D Janciauskas ◽  
S Vaitkus
Keyword(s):  
Helicobacter Pylori ◽  
Laryngopharyngeal Reflux ◽  
Chronic Tonsillitis ◽  
Control Group ◽  
Tonsillar Hypertrophy ◽  
Posterior Commissure ◽  
Tissue Samples ◽  
Tonsillar Tissue ◽  
Significant Relationships ◽  
H Pylori

AbstractObjective:To identify Helicobacter pylori infection in tonsillar tissue samples from patients undergoing tonsillectomy for chronic tonsillitis versus tonsillar hypertrophy, and to assess the possible relationships between H pylori and patients’ sociodemographic data and laryngopharyngeal reflux.Methods:In this prospective study, 97 patients who underwent tonsillectomy were divided into the following 2 groups: patients with chronic tonsillitis (n = 62) and patients with tonsillar hypertrophy (control group; n = 35). H pylori infection in the tonsillar biopsy samples was identified using histochemical and rapid urease tests.Results:The incidence of H pylori infection was significantly higher in the chronic tonsillitis group (56.5 per cent) compared to the control group (31.4 per cent). Similar findings were obtained for both subgroups of adults (68.6 vs 42.3 per cent) and children (40.7 vs 0.0 per cent). Significant relationships between a positive H pylori finding and laryngopharyngeal reflux related signs of vocal fold oedema, diffuse laryngeal oedema and hypertrophy of the posterior commissure were revealed.Conclusion:H pylori infection may be related to chronic tonsillitis and laryngopharyngeal reflux.

scholarly journals Overview of Helicobacter pylori Detection Using Rapid Urease Test and Giemsa Modification Staining in Chronic Tonsillitis Patients

2020 ◽  
Vol 8 (B) ◽  
pp. 1105-1109
Author(s):  
Ade Asyari ◽  
Ferdy Azman ◽  
Novialdi Novialdi ◽  
Aziz Djamal ◽  
Hafni Bachtiar ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Descriptive Study ◽  
Chronic Tonsillitis ◽  
Rapid Urease Test ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Tonsillar Tissue ◽  
Urease Test ◽  
Tonsil Tissue ◽  
H Pylori

BACKGROUND: Helicobacter pylori (H. pylori) is a Gram-negative bacteria and has been known for its role in causing gastric infection aused diseases such as gastric ulcer. H. pylori also implied to play a role in chronic tonsillitis, but this theory remains controversial. Many researches have different and contradictory results due to difficulty to accurately detect H. pylori in tonsillar tissue. There is still no appropriate method that able to detect H. pylori in tonsil tissue. AIM: The aim of the study was to detect H. pylori colonization in chronic tonsillitis and understand some of the methods of examination that can be done to detect H. pylori in tonsillar tissue. METHODS: This study is a descriptive study conducted on 25 respondents. Each sample was taken from patients with chronic tonsillitis who underwent tonsillectomy. Then, the rapid urease test (RUT) and the Giemsa modification staining were carried out to determine the presence of H. pylori. RESULTS: There were 19 people (76%) positive and 6 people (24%) negative for H. pylori using RUT. On examination with Giemsa modification staining obtained 19 people (76%) positive and 6 people (24%) negative for H. pylori. CONCLUSION: H. pylori can be found in most of chronic tonsillitis. Combination RUT and Giemsa modification staining examination can be a good option in detecting H. pylori in chronic tonsillitis.

scholarly journals A Correlative Study between Chronic Tonsillitis and Helicobacter Pylori

2019 ◽  
Vol 27 (1) ◽  
pp. 60-64
Author(s):  
Abhishek Singh ◽  
Santosh Uttarkar Pandurangarao ◽  
Aravind Darga Ramchandra ◽  
Sridurga Janarthanan
Keyword(s):  
Helicobacter Pylori ◽  
Acute Infection ◽  
Chronic Tonsillitis ◽  
Common Finding ◽  
Rapid Urease Test ◽  
Palatine Tonsils ◽  
Regular Treatment ◽  
Tonsillar Tissue ◽  
Urease Test ◽  
H Pylori

Introduction : Chronic tonsillitis is characterized by persistent inflammation of the palatine tonsils and seen commonly in patients attending ENT OPD. Bacterial infection is usually the cause but anaerobes and viruses may also be implicated. The possibility that tonsillar tissue possesses Helicobacter pylori or that H. pylori can colonize the palatine tonsils is explored. Materials and Methods : Hundred patients aged between 5-50 years of either sex diagnosed with chronic tonsillitis undergoing elective tonsillectomy and willing to participate in the study were selected. Informed and written consent was taken from all the patients (in case of minor patients, consent was taken from parents). Specimen (tonsillar tissue) was harvested from the surgically removed tonsils  and put through Rapid urease test. The results were analysed statistically using Chi square test and Unpaired t test and inference was drawn. Results : Amongst 100 patients, 61 (61%) patients were females and 39 (39%) patients were males. Helicobacter pylori could be detected in Chronic Tonsillitis in 64 (64%) patients. Conclusion : According to our study, Helicobacter pylori was found to be a common finding in cases of chronic tonsillitis. Even after regular treatment with antibiotics, the chances of getting acute  infection in chronic tonsillitis still persist. We can try treatment for H. pylori and look for changes in recurrence of tonsillitis and also it can be tried in patients who are not willing/fit to undergo tonsillectomy.

scholarly journals Prevalence of Helicobacter pylori colonisation in tonsillar tissue in cases of chronic tonsillitis: a prospective study

2018 ◽  
Vol 4 (3) ◽  
pp. 738
Author(s):  
Vellamparambil Sreejaraj ◽  
Paul Vazhapilly Sumam ◽  
Verghese Nevil ◽  
Karuthedath Sridevi ◽  
Ariyamparampil Rajagopalan Vinayakumar
Keyword(s):  
Helicobacter Pylori ◽  
Tertiary Hospital ◽  
Chronic Tonsillitis ◽  
Rapid Urease Test ◽  
Recurrent Tonsillitis ◽  
Cross Sectional ◽  
Female Ratio ◽  
Tonsillar Tissue ◽  
Urease Test ◽  
H Pylori

<p class="abstract"><strong>Background:</strong> Human stomach is not the only reservoir of <em>Helicobacter pylori</em> but it has been detected in dental plaques, oral lesions and saliva. It could play role in the pathogenesis of various otorhinolaryngologic problems and remains debatable. This study was aimed to find out the prevalence of <em>H. pylori</em> in tonsillar tissue of patients with chronic tonsillitis by rapid urease test in a tertiary hospital in Kerala.</p><p class="abstract"><strong>Methods:</strong> Prospective cross sectional study was done in patients who attended the outpatient department of ENT with a history suggestive of chronic tonsillitis. The patient satisfied the criteria for chronic recurrent tonsillitis were subsequently posted for tonsillectomy. Each specimen was subjected to rapid urease test.  </p><p class="abstract"><strong>Results:</strong> Total 228 patients were included in this study with age ranging between 3 and 31 years (10.0±7.1), with most common age being &lt;10 years in 159 patients (69.7%). Male to female ratio was 1.4:1. Among these, the presence of <em>H. pylori</em> was seen in only 6/228 patients.</p><p class="abstract"><strong>Conclusions:</strong> The possibility of tonsillar tissue acting as a reservoir for <em>H. pylori </em>infection is very low.</p>

scholarly journals The Effect of Gastric Helicobacter pylori Colonization on Nasal Functions

2019 ◽  
Vol 98 (6) ◽  
pp. 346-350 ◽  
Author(s):  
Tolgar Lütfi Kumral ◽  
Yasemin Gökden ◽  
Ziya Saltürk ◽  
Güler Berkiten ◽  
Güven Yıldırım ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Laryngopharyngeal Reflux ◽  
Test Results ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Olfactory Test ◽  
Sinonasal Outcome Test ◽  
H Pylori ◽  
Nasal Function ◽  
Snot 22

The aim of this study is to investigate the effect of gastric Helicobacter pylori colonization on nasal functions. The study enrolled patients (n = 100) who underwent endoscopy for gastroesophageal reflux disease. Patients with laryngopharyngeal reflux (LPR) were identified by Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). Patients were divided into 2 groups: LPR (+) (n = 64) H pylori (+), RSI > 13, RFS > 7; LPR (−) (n = 36) H pylori (+), RSI < 13, RFS < 7. Visual analog scale (VAS), sinonasal outcome test-22 (SNOT-22), peak nasal inspiratory flowmeter (PNIF), mucociliary clearance (MCC), and olfactory tests were used to evaluate the nasal functions. The average VAS for nasal obstruction, PNIF, and MCC did not differ significantly between the LPR (+) and LPR (−) groups ( P > .05). However, the average olfactory test scores were lower in the LPR (+) patients than the LPR (−) patients ( P < .05). Also, the SNOT-22 scores were significantly higher in LPR (+) patients than in LPR (−) ( P < .01). Nasal functions and symptom scores were also evaluated according to the H pylori grading. The PNIF, MCC, SNOT-22, and olfactory test results deteriorated as the gastric mucosal H pylori colonization increased ( P < .05). In conclusion, nasal functions differed between LPR disease and GERD only, while the density of H pylori colonization in the gastric mucosa had an effect on nasal function.

Intranasal Helicobacter pylori infection in patients with chronic rhinosinusitis with polyposis

2018 ◽  
Vol 132 (9) ◽  
pp. 816-821 ◽  
Author(s):  
N Siupsinskiene ◽  
I Katutiene ◽  
V Jonikiene ◽  
D Janciauskas ◽  
S Vaitkus
Keyword(s):  
Helicobacter Pylori ◽  
Chronic Rhinosinusitis ◽  
Laryngopharyngeal Reflux ◽  
Statistical Significance ◽  
Control Group ◽  
Clinical Group ◽  
Posterior Commissure ◽  
Nasal Tissue ◽  
H Pylori ◽  
Nasal Biopsy

AbstractObjectiveTo determine the prevalence of Helicobacter pylori infection in nasal biopsy specimens from patients with chronic rhinosinusitis with polyposis versus control patients, and to assess the correlations between H pylori infection identified in the nasal tissue and patients’ sociodemographic data and reflux-related symptoms and signs.MethodsNasal biopsy samples were taken from 75 adult patients who underwent nasal surgery for chronic rhinosinusitis with polyposis (clinical group, n = 45) and a deviated septum (control group, n = 30). H pylori infection was identified using histochemical and rapid urease tests.ResultsThe prevalence of intranasal H pylori infection was significantly higher in the clinical group (28.9 per cent) compared to the control group (3.3 per cent) (p = 0.005). A significant yet weak association was found between positive H pylori status and laryngopharyngeal reflux related hypertrophy of the posterior commissure of the larynx. No other correlations reached statistical significance.ConclusionH pylori infection is potentially related to chronic rhinosinusitis with polyposis. Further research is needed to clarify the role of H pylori as a risk factor for the development of sinonasal diseases and to examine its link with laryngopharyngeal reflux.

scholarly journals The role of environmental tobacco exposure and Helicobacter pylori infection in the risk of chronic tonsillitis in children

2017 ◽  
Vol 135 (1) ◽  
pp. 29-33
Author(s):  
Chen Li’e ◽  
Che Juan ◽  
Jiang Dongying ◽  
Feng Guiling ◽  
Zheng Tihua ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Chronic Tonsillitis ◽  
Tobacco Exposure ◽  
Serum Cotinine ◽  
Cross Sectional ◽  
Significant Difference ◽  
H Pylori ◽  
And Control

ABSTRACT CONTEXT AND OBJECTIVE: Helicobacter pylori (H. pylori) is a chronic infectious pathogen with high prevalence. This study investigated the interaction between environmental tobacco exposure and H. pylori infection on the incidence of chronic tonsillitis in Chinese children. DESIGN AND SETTING: Cross-sectional study performed in an outpatient clinic in China. METHODS: Pediatric patients with chronic tonsillitis were enrolled. H. pylori infection was determined according to the presence of H. pylori CagA IgG antibodies. Serum cotinine levels and environmental tobacco smoke (ETS) exposure were determined for all participants. RESULTS: There was no significant difference in H. pylori infection between the children with chronic tonsillitis and children free of disease, but there was a significant difference in ETS between the two groups (P = 0.011). We next studied the association between ETS and chronic tonsillitis based on H. pylori infection status. In the patients with H. pylori infection, there was a significant difference in ETS distribution between the chronic tonsillitis and control groups (P = 0.022). Taking the participants without ETS as the reference, multivariate logistic regression analysis showed that those with high ETS had higher susceptibility to chronic tonsillitis (adjusted OR = 2.33; 95% CI: 1.67-3.25; adjusted P < 0.001). However, among those without H. pylori infection, ETS did not predispose towards chronic tonsillitis. CONCLUSION: Our findings suggest that tobacco exposure should be a putative mediator risk factor to chronic tonsillitis among children with H. pylori infection.

scholarly journals The Association between Helicobacter Pylori and Laryngopharyngeal Reflux in Laryngeal Pathologies

2012 ◽  
Vol 91 (3) ◽  
pp. E6-E9 ◽  
Author(s):  
Engin Çekin ◽  
Mustafa Ozyurt ◽  
Evren Erkul ◽  
Koray Ergunay ◽  
Hakan Cincik ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Laryngopharyngeal Reflux ◽  
Endoscopic Examination ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Significant Difference ◽  
Laryngeal Lesions ◽  
Polymerase Chain ◽  
The Difference ◽  
H Pylori

We conducted a study to determine the presence or absence of Helicobacter pylori and laryngopharyngeal reflux (LPR) in 43 previously untreated patients who had presented with a laryngeal lesion. Our aim was to determine if there was any association among H pylori, LPR, and laryngeal lesions. H pylori status was determined by real-time polymerase chain reaction (PCR) assays of biopsy tissue obtained during direct laryngoscopy. The presence or absence of LPR was determined on the basis of patients’ reflux symptom index (RSI) and reflux finding score (RFS), which were based on their questionnaire responses and findings on endoscopic examination of the larynx, respectively. Patients with an RSI of 14 or more and/or an RFS of 8 or more were considered to have LPR. H pylori was present in 24 patients (55.8%) and absent in 19 (44.2%)—not a statistically significant difference. The prevalence of LPR was higher than the prevalence of H pylori; it was present in 30 patients (69.8%) and absent in 13 (30.2%). The difference was statistically significant (p = 0.01). We found no association between H pylori status and LPR status. Additionally, we analyzed two subgroups based on whether their lesions were benign or malignant/premalignant and found a significant relationship between LPR positivity and the presence of malignant/premalignant laryngeal lesions (p = 0.03). We found no association between H pylori status and either of the two subgroup categories.

scholarly journals Laryngeal Helicobacter pylori Infection and Laryngeal Cancer-Case Series and a Systematic Review

2021 ◽  
Vol 9 (6) ◽  
pp. 1129
Author(s):  
Li-Jen Hsin ◽  
Hai-Hua Chuang ◽  
Mu-Yun Lin ◽  
Tuan-Jen Fang ◽  
Hsueh-Yu Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Helicobacter Pylori ◽  
Laryngeal Cancer ◽  
Laryngopharyngeal Reflux ◽  
Case Series ◽  
Current Evidence ◽  
Cancer Case ◽  
Digital Literature ◽  
Laryngeal Lesions ◽  
H Pylori

Helicobacter pylori (H. pylori) infection involves the development of gastric cancer and may be associated with laryngeal cancer. However, laryngeal H. pylori infection in Taiwanese patients with newly diagnosed laryngeal cancer has not been reported. This study was aimed to investigate the possible association between laryngeal H. pylori infection and laryngeal cancer in Taiwan and perform a systematic review of previous reports in other countries. An analysis of 105 patients with laryngeal lesions found the positive rates of H. pylori DNA (determined by polymerase chain reaction) and antigen (determined by immunohistochemistry) of the laryngeal lesions were relatively low (vocal polyps: 3% and 3%; vocal fold leukoplakia: 0% and 0%; laryngeal cancers: 0% and 2%). Furthermore, H. pylori-associated laryngopharyngeal reflux and the expression of E-cadherin and CD1d (determined by immunohistochemistry) were comparable among the three subgroups. Fifteen studies were involved in the systematic review of the digital literature database, distributed to February 2021. The data of patients with laryngeal cancer and controls showed that the laryngeal H. pylori infection rates were 29.4% and 16.7%, respectively. Although current evidence supported that laryngeal H. pylori infection was associated with laryngeal cancer globally, it might not play a role in the development of laryngeal cancer in Taiwan.

The rod-to-coccoid body transformation in cultures of Helicobacter pylori

1990 ◽  
Vol 48 (3) ◽  
pp. 626-627
Author(s):  
A. R. Crooker ◽  
W. G. Kraft ◽  
T. L. Beard ◽  
M. C. Myers
Keyword(s):  
Helicobacter Pylori ◽  
Growth Cycle ◽  
Negative Bacterium ◽  
Body Formation ◽  
Coccoid Form ◽  
Spiral Form ◽  
Prolonged Culture ◽  
H Pylori ◽  
Upper Gastrointestinal

Helicobacter pylori is a microaerophilic, gram-negative bacterium found in the upper gastrointestinal tract of humans. There is strong evidence that H. pylori is important in the etiology of gastritis; the bacterium may also be a major predisposing cause of peptic ulceration. On the gastric mucosa, the organism exists as a spiral form with one to seven sheathed flagella at one (usually) or both poles. Short spirals were seen in the first successful culture of the organism in 1983. In 1984, Marshall and Warren reported a coccoid form in older cultures. Since that time, other workers have observed rod and coccal forms in vitro; coccoid forms predominate in cultures 3-7 days old. We sought to examine the growth cycle of H. pylori in prolonged culture and the mode of coccoid body formation.

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