scholarly journals A non-invasive photoacoustic and ultrasonic method for the measurement of glucose solution concentration

AIP Advances ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 035313 ◽  
Author(s):  
Siwei Zhao ◽  
Wei Tao ◽  
Qiaozhi He ◽  
Hui Zhao ◽  
Wenwu Cao
2013 ◽  
Vol 456 ◽  
pp. 652-655
Author(s):  
Guo Dong Liu ◽  
Jian Dong ◽  
Zhong Ren ◽  
Lv Ming Zeng ◽  
Hao Xu

In the near-infrared region, we can test the blood glucose by non-invasive method. Based on this theory, combined photoacoustic principle, we had research about the simulated samples of blood glucose, measured the concentration of glucose solution. We have discussed the optimal wavelength in the near-infrared region (780-2400nm), and did the experiment repeatedly, and then analyzed data through the linear, polynomial and exponential fitting of the Generalized Least Squares, the measuring accuracy of the glucose solution had improved. These research results provide the guidance on the practice and experimental evidence for the further research of measuring.


2011 ◽  
Vol 301-303 ◽  
pp. 1139-1144
Author(s):  
Li Ying Jiang ◽  
Li Jie Ren ◽  
Qing Hua Chen ◽  
Guang Zhao Cui

According to the relationship of glucose content in diabetes saliva and blood, the biosensor for detecting saliva glucose was introduced based on electrochemical detecting principle, glucose oxidase was immobilized onto the surface of electrode by glutaraldehyde cross-linking. The measuring system was designed by using potentiostat for amperometric chemical sensors. The characters of the microsystem has been demonstrated with the detection of standard glucose solution concentration of saliva parameter. Compared with the data obtained from the instrument CHI660A, it showed that has a good linear relation in the linear range of 0-2200µmol/L, with the correlation coefficient of 0.9531.


2021 ◽  
Vol 13 (2) ◽  
pp. 110-116
Author(s):  
Kemal Thoriq Al-Azis ◽  
Alfian Ma'arif ◽  
Sunardi Sunardi ◽  
Fatma Nuraisyah ◽  
Apik Rusdiarna Indrapraja

Early and routine examination of glucose levels plays an important role in preventing and controlling diabetes mellitus and maintaining the quality of life. Checking blood sugar levels by hurting the body (invasive) can lead to infections caused by needles. As an alternative, the examination is carried out in a non-invasive way using excretory fluid in the form of urine, which is reacted with Benedict's solution that create a color change. Experts in the laboratory only carry out an examination using non-invasive methods because in determining glucose levels, it requires accuracy and eye health factors. Therefore, a glucose level detection system was created using a sample of glucose solution to determine the system's parameters using the if-else method. The glucose level detection system is conducted by mixing the glucose solution with Benedict's solution to produce a color change. Then the reaction results are read by the TCS3200 sensor and processed by Arduino to be classified, according to predetermined parameters. The decision results based on the classification of the glucose level parameters that have been determined are displayed on a 16x2 LCD. The results achieved in this study on 10 samples of glucose solution that were tested and processed by the if-else method were successfully read and classified based on predetermined parameters.


2013 ◽  
Vol 284-287 ◽  
pp. 2885-2889
Author(s):  
Yun Dong Zhang ◽  
Jing Zhang ◽  
He Tian ◽  
Ping Yuan

We present the microsphere coupled Mach–Zehnder interference structure. We theoretically calculate that spectral responses of this structure vary with the glucose solution concentrations. It can produce the sharply asymmetric Fano resonance line shape related to the slope between zero and unity transmission. The variation of the normalized transmission is linearly related to the solution concentration. This structure is the promising highly sensitive biochemical sensor due to high quality factor resonance and steep slope over a very narrow frequency range


2017 ◽  
Vol 24 (02) ◽  
pp. 1750017 ◽  
Author(s):  
XUEYE CHEN ◽  
TIECHUAN LI ◽  
BAODING FU

A novel method named soak sacrificial layer ultrasonic method (SSLUM) has been presented for optimizing the surface roughness of the microchannels of polymethyl methacrylate (PMMA)-based microfluidic chips. CO2 laser was used for ablative microchannels on the PMMA sheet, and the effects of key parameters including laser power, laser ablation speed and solution concentration on the surface roughness of microchannels were estimated and optimized by SSLUM. The experimental observation demonstrates that the surface roughness results mainly from the residues on the channel wall, which are produced by the bubbles movement and bursting. The research results show that the surface roughness can be improved effectively by using SSLUM. In our experiment, the best value was Ra [Formula: see text] 110[Formula: see text]nm with laser power 12[Formula: see text]W, laser ablation speed 10[Formula: see text]mm/s, the solution concentration 75%, and the time of ultrasonic vibration 25[Formula: see text]min. SSLUM is proven to be an effective, simple and rapid method for optimizing the surface roughness of microchannels of microfluidic chips.


2010 ◽  
Vol 30 (1) ◽  
pp. 276-281 ◽  
Author(s):  
Alda Jusceline Leonel ◽  
Hulda Noemi Mamani Chambi ◽  
Daniel Barrera-Arellano ◽  
Heloise Oliveira Pastore ◽  
Carlos Raimundo Ferreira Grosso

The objective of this research was to produce and characterize lipid particles (MpLs) that may be used as carriers of high amounts of hydrophilic core and evaluate the influence of the core amount on the performance of lipid microparticles. The MpLs were produced by spray cooling from solid and liquid lipid mixtures (stearic and oleic fatty acids and partly hydrogenated vegetable fat) containing glucose solution as core and soy lecithin as surfactant. The performance of MpLs was evaluated by means of the effective amount of encapsulated core, the core amount present on the surface of MpLs (superficial glucose) and the core release profile in aqueous solution. Morphological observations showed that MpLs presented spherical shape and a rugged and continuous surface, and an average diameter between 25 and 32 µm. The effective amount of encapsulated core was greater than 78% for all formulations evaluated. Larger amounts of superficial glucose were found in formulations in which more concentrated glucose solutions were used, regardless of the glucose lipid-solution ratio. The release results showed that core retention was significantly influenced by the glucose solution concentration, whereas release modulation was influenced by the glucose lipid-solution ratio.


Author(s):  
T.G. Hertz ◽  
S.O. Dymling ◽  
H.W. Persson ◽  
K. Lindstrom

2012 ◽  
Vol 32 (4) ◽  
pp. 323-329 ◽  
Author(s):  
Lili Niu ◽  
Ming Qian ◽  
Ruibo Song ◽  
Long Meng ◽  
Xin Liu ◽  
...  

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