Analysis of the body gas exchange indicators in high-altitude flight on the basis of the static model of the respiratory system

2021 ◽  
Author(s):  
T. V. Matyushev ◽  
M. V. Dvornikov ◽  
S. P. Ryzhenkov ◽  
M. A. Petrov
Author(s):  
T.V. Matyushev ◽  
M.V. Dvornikov ◽  
S.P. Ryzhenkov ◽  
M.A. Petrov

The purpose of the research was to analyze the dynamics of indicators of human gas exchange in high-altitude flight on the basis of a static model of the respiratory system of the body. First, we developed the structure of this model and an algorithm for calculating the gas exchange of the body. Next, we analyzed changes in indicators of the function of external respiration and gas exchange, and clarified the quantitative parameters that determine the nature of the relationships between the components of gas exchange. Finally, we carried out a computational experiment to simulate ascent to a height. The results of the analysis of the calculations showed that when a person rises to a height with a drop in pressure, tidal volumes change the volume of the alveolar space decreases and the dead space increases in the ratio from 4.7 to 0.7. An uncompensated respiratory alkalosis develops, leading to a violation of the acid-base reactions of the body.


2021 ◽  
Author(s):  
N.V. Balioz ◽  
S.G. Krivoshshekov

An exploration of 110 healthy men (not involved in sports and athletes) with the use of hypoxic loads was carried out. It is established that the specifics of the regulation of gas exchange depend on the nature of training loads (aerobic or mixed), which are manifested in the parameters of chemoreflector reactivity, the pattern of external respiration, gas exchange and activity of the autonomic nervous system under hypoxic load. As sports qualifications grow, the mechanisms of intersystem integration of the functions of the cardio-respiratory system are improved, which is manifested in an increase in cardiorespiratory coherence. Key words: athletes, hypoxia, cardiorespiratory system, gas exchange of the body, chemoreceptor reactivity.


2016 ◽  
Vol 121 (2) ◽  
pp. 512-517 ◽  
Author(s):  
Andrew T. Lovering ◽  
Jonathan E. Elliott ◽  
James T. Davis

The foramen ovale, which is part of the normal fetal cardiopulmonary circulation, fails to close after birth in ∼35% of the population and represents a potential source of right-to-left shunt. Despite the prevalence of patent foramen ovale (PFO) in the general population, cardiopulmonary, exercise, thermoregulatory, and altitude physiologists may have underestimated the potential effect of this shunted blood flow on normal physiological processes in otherwise healthy humans. Because this shunted blood bypasses the respiratory system, it would not participate in either gas exchange or respiratory system cooling and may have impacts on other physiological processes that remain undetermined. The consequences of this shunted blood flow in PFO-positive (PFO+) subjects can potentially have a significant, and negative, impact on the alveolar-to-arterial oxygen difference (AaDO2), ventilatory acclimatization to high altitude and respiratory system cooling with PFO+ subjects having a wider AaDO2 at rest, during exercise after acclimatization, blunted ventilatory acclimatization, and a higher core body temperature (∼0.4°C) at rest and during exercise. There is also an association of PFO with high-altitude pulmonary edema and acute mountain sickness. These effects on physiological processes are likely dependent on both the presence and size of the PFO, with small PFOs not likely to have significant/measureable effects. The PFO can be an important determinant of normal physiological processes and should be considered a potential confounder to the interpretation of former and future data, particularly in small data sets where a significant number of PFO+ subjects could be present and significantly impact the measured outcomes.


1998 ◽  
Vol 201 (18) ◽  
pp. 2665-2668 ◽  
Author(s):  
D F Boggs ◽  
P J Butler ◽  
S E Wallace

The air in the respiratory system of diving birds contains a large proportion of the body oxygen stores, but it must be in the lungs for gas exchange with blood to occur. To test the hypothesis that locomotion induces mixing of air sac air with lung air during dives, we measured differential pressures between the interclavicular and posterior thoracic air sacs in five diving tufted ducks Aythya fuligula. The peak differential pressure between posterior thoracic and interclavicular air sacs, 0.49+/-0.13 kPa (mean +/- s.d.), varied substantially during underwater paddling as indicated by gastrocnemius muscle activity. These data support the hypothesis that locomotion, perhaps through associated abdominal muscle activity, intermittently compresses the posterior air sacs more than the anterior ones. The result is differential pressure fluctuations that might induce the movement of air between air sacs and through the lungs during dives.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.


Author(s):  
Divya Venkat ◽  
Kurwandeep Dhillon ◽  
James A. Rowley

2019 ◽  
Vol 96 (8) ◽  
pp. 766-769 ◽  
Author(s):  
Inessa V. Averyanova ◽  
S. I. Vdovenko ◽  
A. L. Maksimov

Natural and climatic conditions of the environment of Northeast Russia and particularly Magadan region are the very factor mostly influencing adaptive responses by individuals inhabiting the region. Compensatory and adaptive responses in indigenes and newcomers of the region can be assumed to have their specific features. In 2009 there was executed the examination of the cardiovascular and respiratory systems and gas exchange in 392 cases aged of 17-19 years, including Europeans (Caucasians) born in the North in the 1st-2nd generation and indigenes. The methodologically similar study was carried out in 2014 in 265 persons, referred to the same cohorts of North-born Caucasians and Indigenes from the Magadan region. The results of the study executed in 2009 testified to a small number of physiological parameters that were reliably different in Caucasians vs. Indigene subjects. In 2014 no difference was found between the two examined cohorts throughout the observed parameters. The revealed changes in gas exchange, external respiration and cardiovascular systems demonstrated by modern young Indigenes of Northeast Russia testified to the fall in the effectiveness of their breathing. All that makes them farther from the classic “polar metabolic type” and their morphofunctional status becomes closer to European male subjects of Northeast Russia. Thus, we can observe a clear tendency towards “convergence in programs” of the adaptive changes between populations of the North residents undergoing similar natural, environmental and social factors.


Author(s):  
Irina Masliak ◽  
Krivoruchko Natalia ◽  
Yuliia Slobodianiuk

The article provides the results of determining the level of physical development of the 1th-2nd course students of design specialties of the College of Construction, Architecture and Design. The physical development of students was determined by indicators of harmony of the bodybuilding (Kettle index 2), functional state of the cardiovascular system (Ruffier index), and respiratory system (Stange test). Length and weight of the body, heart rate, breathing delay time were measured. As a result of the researches, the “average” level of the physical development is determined in the 1th-2nd course girls and “sufficient” - in boys. Thus, mass-growth indicators of students according to the calculation of Kettle 2 index, both boys and girls correspond to the assessment of 5 points, which indicates a harmonious physique of students; indicators of the functioning of the cardiovascular system (Ruffier Index) of 1st year boys and the 2nd year students make 2 points, which corresponds to the ”below average” level, and the results of the 1st year girls equal to the assessment of 3 points, “average” level; indicators of the functional state of the respiratory system (Stange test) of boys of the 1th-2nd  course correspond to the assessment of 4 points (“above the average” level), and girls of both courses - 3 points (“average” level). In the age and gender aspects, physical development indicators, in general, don’t significantly differ with the general tendency to increase results with age and the dominance of boys over such in girls. The exception is the Ruffier index, where there is an opposite trend - the results decrease with age in girls and they are higher than in boys. Thus, the results of the research indicate the feasibility of introducing the 1th-2nd course students of professional pre-high education of special physical exercises into the process of physical education to improve the functional state of the cardiovascular and respiratory systems.


2019 ◽  
Author(s):  
John Yerxa ◽  
Cory J Vatsaas ◽  
Suresh Agarwal

Respiratory system uses an elegant physiologic mechanism to support the metabolic demands of the body through oxygenation and ventilation. Oxygen must be absorbed and delivered to the tissues to sustain oxidative metabolism, whereas carbon dioxide must be expelled in a delicate balance to maintain an acid-base equilibrium. Complete understanding of oxygen content, delivery, consumption, and carbon dioxide elimination is essential as a provider caring for the critically ill patient. This review contains 13 figures and 25 references. Key Words: oxygenation, respiratory system, ventilation, gas exchange, haemoglobin, respiratory physiology, respiratory anatomy, oxidative metabolism, dead space.


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